Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model

Spine

Volumn 31, Issue 7, 2006, Pages 742-754

  Masuda, Koichi ^a,b   Imai, Yoshiyuki ^a   Okuma, Masahiko ^a   Muehleman, Carol ^a   Nakagawa, Koichi ^a   Akeda, Koji ^a   Thonar, Eugene ^a   Andersson, Gunnar ^a   An, Howard S ^a  

^a RUSH MEDICAL COLLEGE   (United States)

^b Cohn 720 ^*  (United States)

Author keywords

An animal model; Biochemistry; Bone morphogenetic protein; Growth factor; Injection; Intervertebral disc; Osteogenic protein 1

Indexed keywords

LACTOSE; PROTEOGLYCAN; RECOMBINANT OSTEOGENIC PROTEIN 1; WATER;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CELL METABOLISM; CELL STRUCTURE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; EUTHANASIA; HISTOLOGY; IN VIVO STUDY; INJECTION; INTERVERTEBRAL DISK DEGENERATION; NEEDLE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEUS PULPOSUS; OSTEOMETRY; PRIORITY JOURNAL; RABBIT; SCORING SYSTEM; SPINE; SPINE RADIOGRAPHY; TIME SERIES ANALYSIS; TREATMENT DURATION; WATER CONTENT;

ANIMALS; BONE MORPHOGENETIC PROTEINS; DISEASE MODELS, ANIMAL; INJECTIONS, SPINAL; INTERVERTEBRAL DISK; RABBITS; SPINAL DISEASES; TRANSFORMING GROWTH FACTOR BETA;

EID: 33645765778     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/01.brs.0000206358.66412.7b     Document Type: Article

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