Synthesis and cytotoxic evaluation of thiourea and N-bis-benzothiazole derivatives: A novel class of cytotoxic agents

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 453-455

  Kumbhare, Ravindra M ^a   Dadmal, Tulshiram ^a   Kosurkar, Umesh ^a   Sridhar, V ^a   Rao, J Venkateswara ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

1,3 Di n butylimidazolium tribromide bbim Br 3 ; Benzothiazolyl thiocarbamide; Chemoselective oxidative cyclization; Cytotoxic activity; N Bis benzothiazole

Indexed keywords

1,3 DI N BUTYLIMIDAZOLIUM TRIBROMIDE; 4 DIMETHYLAMINOPYRIDINE; BENZOTHIAZOLE DERIVATIVE; BENZOTHIAZOLYL THIOCARBAMIDE; CYTOTOXIC AGENT; ETOPOSIDE; N BIS BENZOTHIAZOLE DERIVATIVE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYCLIZATION; CYTOTOXICITY; DRUG ACTIVITY; DRUG OXIDATION; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MELANOMA CELL; MONOCYTE;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; CATALYSIS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HUMANS; INHIBITORY CONCENTRATION 50; MELANOMA, EXPERIMENTAL; MICE; MODELS, CHEMICAL; MOLECULAR STRUCTURE; THIOUREA; U937 CELLS;

EID: 84655163397     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.10.106     Document Type: Article

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