Effect of stereochemistry on the anti-HIV activity of chiral thiourea compounds

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 15, 2004, Pages 4275-4284

  Venkatachalam, T K ^a   Mao, C ^a   Uckun, Fatih M ^a  

^a PARKER HUGHES INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N (1 ALPHA METHYLBENZYL) N' [2 (4 METHYLBENZOTHIAZOLYL)]THIOUREA; N (1 ALPHA METHYLBENZYL) N' [2 (4 METHYLPYRIDYL)]THIOUREA; N (1 ALPHA METHYLBENZYL) N' [2 (4 METHYLTHIAZOLYL)]THIOUREA; N (1 ALPHA METHYLBENZYL) N' [2 (5 BROMOPYRIDYL)]THIOUREA; N (1 ALPHA METHYLBENZYL) N' [2 (5 CHLOROPYRIDYL)]THIOUREA; N (1 ALPHA METHYLBENZYL) N' [2 (5 METHYLPYRIDYL)]THIOUREA; N (1 ALPHA METHYLBENZYL) N' [2 (6 METHOXYBENZOTHIAZOLYL)]THIOUREA; N (1 ALPHA METHYLBENZYL) N' [2 (6 METHYLPYRIDYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' (2 PYRIDYL)THIOUREA; N (BETA METHYLPHENYLETHYL) N' (2 THIAZOLYL)THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (4 METHYLBENZOTHIAZOLYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (4 METHYLENECARBOETHOXYTHIAZOLYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (4 METHYLTHIAZOLYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (4,6 DIMETHYLPYRIDYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (5 BROMOPYRIDYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (5 CHLOROPYRIDYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (5 METHYLPYRIDYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (6 METHYLPYRIDYL)]THIOUREA; N (BETA METHYLPHENYLETHYL) N' [2 (BENZOTHIAZOLYL)]THIOUREA; RNA DIRECTED DNA POLYMERASE INHIBITOR; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CHIRALITY; DATA ANALYSIS; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; INHIBITION KINETICS; PERIPHERAL BLOOD MONONUCLEAR CELL; STEREOCHEMISTRY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; VIRUS REPLICATION; VIRUS STRAIN;

ANTI-HIV AGENTS; DRUG EVALUATION, PRECLINICAL; HIV-1; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; REVERSE TRANSCRIPTASE INHIBITORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIOUREA; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 3042836102     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.04.050     Document Type: Article

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