Antitumor benzothiazoles. 8.1 Synthesis, metabolic formation, and biological properties of the C- and N-oxidation products of antitumor 2-(4- aminophenyl)-benzothiazoles

Journal of Medicinal Chemistry

Volumn 42, Issue 20, 1999, Pages 4172-4184

  Kashiyama, Eiji ^a   Hutchinson, Ian ^b   Chua, Mei Sze ^b   Stinson, Sherman F ^a   Phillips, Lawrence R ^a   Kaur, Gurmeet ^a   Sausville, Edward A ^a   Bradshaw, Tracey D ^b   Westwell, Andrew D ^b   Stevens, Malcolm F G ^b  

^a National Cance Institute   (United States)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 AMINO 3 METHYLPHENYL)BENZOTHIAZOLE; 2 (4 AMINOPHENYL)BENZOTHIAZOLE; BENZOTHIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG SYNTHESIS; GROWTH INHIBITION; OXIDATION;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; CULTURE MEDIA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; OXIDATION-REDUCTION; RADIOLIGAND ASSAY; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0033533836     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990104o     Document Type: Article

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