Synthesis of carbon-11 labeled fluorinated 2-arylbenzothiazoles as novel potential PET cancer imaging agents

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 24, 2006, Pages 8599-8607

  Wang, Min ^a   Gao, Mingzhang ^a   Mock, Bruce H ^a   Miller, Kathy D ^a   Sledge, George W ^a   Hutchins, Gary D ^a   Zheng, Qi Huang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer imaging; Carbon 11; Fluorinated 2 arylbenzothiazoles; Positron emission tomography (PET); Tyrosine kinase

Indexed keywords

3 [4 FLUORO 2 (3,4 DIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; 3 [5 FLUORO 2 (3,4 DIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; 3 [6 FLUORO 2 (3,4 DIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; 3 AMINOPHENOL; 4 [5 FLUORO 2 (3,4 DIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; 4 [5 FLUORO 2 (3,4,5 TRIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; 4 [6 FLUORO 2 (3,4 DIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; 4 [6 FLUORO 2 (3,4,5 TRIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; 5 [5 FLUORO 2 (3,4,5 TRIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; 5 [6 FLUORO 2 (3,4,5 TRIMETHOXYPHENYL)BENZOTHIAZOLE] C 11; BENZALDEHYDE; DISULFIDE; HYDROXYL GROUP; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CANCER INHIBITION; CELL CULTURE; CELL LINE; COLON CANCER; CYCLIZATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; ISOTOPE LABELING; LUNG CANCER; METHYLATION; POSITRON EMISSION TOMOGRAPHY; PRECURSOR; RADIOASSAY; SOLID PHASE EXTRACTION;

ANIMALS; BENZOTHIAZOLES; CARBON RADIOISOTOPES; HUMANS; NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 33750507472     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.08.026     Document Type: Article

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