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Volumn 10, Issue 4, 2012, Pages 736-745

Cyclopropane-based stereochemical diversity-oriented conformational restriction strategy: Histamine H 3 and/or H 4 receptor ligands with the 2,3-methanobutane backbone

(10) Watanabe, Mizuki a Kobayashi, Takaaki a Hirokawa, Takatsugu b Yoshida, Akira c Ito, Yoshihiko c Yamada, Shizuo c Orimoto, Naoki d Yamasaki, Yasundo d Arisawa, Mitsuhiro a Shuto, Satoshi a

a HOKKAIDO UNIVERSITY (Japan)

b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST (Japan)

c UNIVERSITY OF SHIZUOKA (Japan)

d TAIHO PHARMACEUTICAL CO LTD (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGONISTIC ACTIVITY; DRUG TARGETS; HYDROPHOBIC GROUPS; PHARMACOLOGICAL PROPERTIES; RECEPTOR ANTAGONISTS; RECEPTOR LIGANDS; SIDE-CHAINS;

BUTANE; FUNCTIONAL GROUPS; LIGANDS;

PROPANE;

CYCLOPROPANE DERIVATIVE; DRUG DERIVATIVE; G PROTEIN COUPLED RECEPTOR; HISTAMINE; HISTAMINE AGONIST; HISTAMINE H3 RECEPTOR; HISTAMINE RECEPTOR; HRH4 PROTEIN, HUMAN; LIGAND;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; HUMAN; METABOLISM; PROTEIN BINDING; STEREOISOMERISM;

CYCLOPROPANES; HISTAMINE; HISTAMINE AGONISTS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; RECEPTORS, HISTAMINE H3; STEREOISOMERISM;

EID: 84555196124 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/c1ob06496g Document Type: Article

Times cited : (15)

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