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Volumn 67, Issue 5, 2002, Pages 1669-1677
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Development of versatile cis- and trans-dicarbon-substituted chiral cyclopropane units: Synthesis of (1S,2R)- and (1R,2R)-2-aminomethyl-1-(1H-imidazol-4-yl)cyclopropanes and their enantiomers as conformationally restricted analogues of histamine
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Author keywords
[No Author keywords available]
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Indexed keywords
KEY INTERMEDIATES;
AMINES;
CARBON;
CONFORMATIONS;
SULFONATION;
SYNTHESIS (CHEMICAL);
PROPANE;
2 (TERT BUTYLDIPHENYLSILYLOXY)METHYL 1 FORMYLCYCLOPROPANE;
2 AMINOMETHYL 1 (1H IMIDAZOL 4 YL)CYCLOPROPANE;
ACETONITRILE DERIVATIVE;
ALCOHOL;
CYCLOPROPANE DERIVATIVE;
EPICHLOROHYDRIN;
HISTAMINE DERIVATIVE;
MAGNESIUM;
METHANOL;
N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;
PHENYLSULFONYLACETONITRILE;
UNCLASSIFIED DRUG;
ARTICLE;
CHIRALITY;
CIS TRANS ISOMERISM;
DRUG CONFORMATION;
DRUG SYNTHESIS;
ENANTIOMER;
GEL CHROMATOGRAPHY;
PROTON NUCLEAR MAGNETIC RESONANCE;
CHROMATOGRAPHY;
CYCLOPROPANES;
HISTAMINE;
IMIDAZOLES;
MAGNETIC RESONANCE SPECTROSCOPY;
MOLECULAR STRUCTURE;
STEREOISOMERISM;
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EID: 0037040657
PISSN: 00223263
EISSN: None
Source Type: Journal
DOI: 10.1021/jo010852x Document Type: Article |
Times cited : (82)
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References (46)
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