Structure and mechanism of a cysteine sulfinate desulfinase engineered on the aspartate aminotransferase scaffold

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1824, Issue 2, 2012, Pages 339-349

  Fernandez, Francisco J ^a   De Vries, Dominique ^b   Peña Soler, Esther ^a,c   Coll, Miquel ^c   Christen, Philipp ^b   Gehring, Heinz ^b   Vega, M Cristina ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

Author keywords

Aspartate aminotransferase; Protein engineering; Pyridoxal 5 phosphate

Indexed keywords

ASPARTATE AMINOTRANSFERASE; ASPARTIC ACID; CARBOXYLIC ACID; CYSTEINE; CYSTEINE SULFINATE DESULFINASE; ENZYME; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAMINE PHOSPHATE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ENGINEERING; CRYSTAL STRUCTURE; DECARBOXYLATION; ENZYME ACTIVITY; ENZYME STRUCTURE; MUTATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTON TRANSPORT; TRANSAMINATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS, DICARBOXYLIC; ASPARTATE AMINOTRANSFERASES; BIOCATALYSIS; CARBON-SULFUR LYASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PYRIDOXAL PHOSPHATE; PYRIDOXAMINE; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI;

EID: 83455235662     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.10.016     Document Type: Article

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