Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy

Cancer Research

Volumn 65, Issue 10, 2005, Pages 4368-4375

  Daido, Shigeru ^a   Yamamoto, Akitsugu ^b   Fujiwara, Keishi ^a   Sawaya, Raymond ^a   Kondo, Seiji ^a   Kondo, Yasuko ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DNA DEPENDENT PROTEIN KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN P70; S6 KINASE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CELL PROLIFERATION; CELL STRAIN M059J; CELL STRAIN M059K; CELL SURVIVAL; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; DRUG SENSITIVITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; GLIOBLASTOMA; HUMAN; HUMAN CELL; IONIZING RADIATION; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RADIATION DOSE; RADIOSENSITIVITY; SIGNAL TRANSDUCTION;

APOPTOSIS; AUTOPHAGY; CATALYTIC DOMAIN; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; GLIOMA; HUMANS; NUCLEAR PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN SUBUNITS; PROTEIN-SERINE-THREONINE KINASES; RADIATION TOLERANCE;

EID: 20144373772     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-4202     Document Type: Article

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