메뉴 건너뛰기




Volumn 9, Issue 4, 2011, Pages 715-727

cGMP signaling, phosphodiesterases and major depressive disorder

Author keywords

Antidepressants; Cyclases; Cyclic guanosine monophosphate; Major Depression; Neurogenesis; Neuroplasticity; Pharmacology; Phophodiesterases

Indexed keywords

2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL] 5 MORPHOLINO 4,6 PYRIMIDINEDIAMINE; 4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; 7 NITROINDAZOLE; ADENOSINE; AMFEBUTAMONE; AMRINONE; ANAGRELIDE; ARGININE; ATROPINE; BAY 607550; CILOSTAZOL; CINACIGUAT; CITALOPRAM; CYCLIC AMP; CYCLIC GMP; FLUOXETINE; IMIDAZOLE; IMIPRAMINE; METHYLENE BLUE; MILRINONE; N(G) NITROARGININE METHYL ESTER; ND 7001; NITRIC OXIDE SYNTHASE INHIBITOR; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; POSTSYNAPTIC RECEPTOR; RIOCIGUAT; SEROTONIN TRANSPORTER; SILDENAFIL; TADALAFIL; TIANEPTINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VARDENAFIL; VENLAFAXINE;

EID: 82955192554     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/157015911798376271     Document Type: Review
Times cited : (58)

References (130)
  • 1
    • 0031909575 scopus 로고    scopus 로고
    • Epidemiology of recurrent major and minor depression with a seasonal pattern. The National comorbidity survey
    • Blazer, D.G., Kessler, R.C., Swartz, M.S. Epidemiology of recurrent major and minor depression with a seasonal pattern. The National comorbidity survey. Br. J. Psychiatry, 1998, 172, 164-167.
    • (1998) Br. J. Psychiatry , vol.172 , pp. 164-167
    • Blazer, D.G.1    Kessler, R.C.2    Swartz, M.S.3
  • 2
    • 1242263295 scopus 로고    scopus 로고
    • From monoamines to genomic targets: A paradigm shift for drug discovery in depression
    • Discov
    • Wong, M.L., Licinio, J. From monoamines to genomic targets: a paradigm shift for drug discovery in depression. Nat. Rev. Drug, 2004, Discov., 3, 136-151.
    • (2004) Nat. Rev. Drug , vol.3 , pp. 136-151
    • Wong, M.L.1    Licinio, J.2
  • 3
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stressrelated mood disorders
    • Duman, R.S., Monteggia, L.M. A neurotrophic model for stressrelated mood disorders. Biol. Psychiatry, 2006, 59, 1116-1127.
    • (2006) Biol. Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 4
    • 40049093899 scopus 로고    scopus 로고
    • Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice
    • Duman, C.H., Schlesinger, L., Russell, D.S., Duman, R.S. Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice. Brain Res., 2008, 1199, 148-158.
    • (2008) Brain Res. , vol.1199 , pp. 148-158
    • Duman, C.H.1    Schlesinger, L.2    Russell, D.S.3    Duman, R.S.4
  • 5
    • 77952415052 scopus 로고    scopus 로고
    • Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity
    • Chen, C.C., Yang, C.H., Huang, C.C., Hsu, K.S. Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity. Neuropsychopharmacology, 2010, 35, 1605-1617.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1605-1617
    • Chen, C.C.1    Yang, C.H.2    Huang, C.C.3    Hsu, K.S.4
  • 6
    • 0032538271 scopus 로고    scopus 로고
    • CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation
    • Bartsch, D., Casadio, A., Karl, K.A., Serodio, P., Kandel, E.R. CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation. Cell, 1998, 95, 211-223.
    • (1998) Cell , vol.95 , pp. 211-223
    • Bartsch, D.1    Casadio, A.2    Karl, K.A.3    Serodio, P.4    Kandel, E.R.5
  • 7
    • 0037092432 scopus 로고    scopus 로고
    • cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs
    • Conti, A.C., Cryan, J.F., Dalvi, A., Lucki, I., Blendy, J.A. cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs. J. Neurosci., 2002, 22, 3262-3268.
    • (2002) J. Neurosci. , vol.22 , pp. 3262-3268
    • Conti, A.C.1    Cryan, J.F.2    Dalvi, A.3    Lucki, I.4    Blendy, J.A.5
  • 8
    • 35048840777 scopus 로고    scopus 로고
    • Effect of addition of yohimbine (alpha-2 receptor antagonist) to the antidepressant activity of fluoxetine or venlafaxine in the mouse forced swim test
    • Dhir, A., Kulkarni, S.K. Effect of addition of yohimbine (alpha-2 receptor antagonist) to the antidepressant activity of fluoxetine or venlafaxine in the mouse forced swim test. Pharmacology, 2007, 80, 239-243.
    • (2007) Pharmacology , vol.80 , pp. 239-243
    • Dhir, A.1    Kulkarni, S.K.2
  • 9
    • 26044476870 scopus 로고    scopus 로고
    • Distribution of cGMP-dependent protein kinase type I and its isoforms in the mouse brain and retina
    • Feil, S., Zimmermann, P., Knorn, A., Brummer, S., Schlossmann, J., Hofmann, F., Feil, R. Distribution of cGMP-dependent protein kinase type I and its isoforms in the mouse brain and retina. Neuroscience, 2005, 135, 863-868.
    • (2005) Neuroscience , vol.135 , pp. 863-868
    • Feil, S.1    Zimmermann, P.2    Knorn, A.3    Brummer, S.4    Schlossmann, J.5    Hofmann, F.6    Feil, R.7
  • 11
    • 34247489688 scopus 로고    scopus 로고
    • Involvement of L-arginine-nitric oxidecyclic guanosine monophosphate pathway in the antidepressantlike effect of venlafaxine in mice
    • Dhir, A., Kulkarni, S.K. Involvement of L-arginine-nitric oxidecyclic guanosine monophosphate pathway in the antidepressantlike effect of venlafaxine in mice. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2007, 31, 921-925.
    • (2007) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.31 , pp. 921-925
    • Dhir, A.1    Kulkarni, S.K.2
  • 12
    • 0343046540 scopus 로고
    • Formation of nitric oxide from L-arginine in the central nervous system: A transduction mechanism for stimulation of the soluble guanylate cyclase
    • Knowles, R.G., Palacios, M., Palmer, R.M., Moncada, S. Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. Proc. Natl. Acad. Sci. U. S. A., 1989, 86, 5159-5162.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 5159-5162
    • Knowles, R.G.1    Palacios, M.2    Palmer, R.M.3    Moncada, S.4
  • 13
    • 0024378999 scopus 로고
    • Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum
    • Bredt, D.S., Snyder, S.H. Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc. Natl. Acad. Sci. U. S. A, 1989, 86, 9030-9033.
    • (1989) Proc. Natl. Acad. Sci. U. S. A , vol.86 , pp. 9030-9033
    • Bredt, D.S.1    Snyder, S.H.2
  • 14
    • 0021987760 scopus 로고
    • Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment
    • Fesenko, E.E., Kolesnikov, S.S., Lyubarsky, A.L. Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment. Nature, 1985, 313, 310-313.
    • (1985) Nature , vol.313 , pp. 310-313
    • Fesenko, E.E.1    Kolesnikov, S.S.2    Lyubarsky, A.L.3
  • 15
    • 0023897806 scopus 로고
    • Auditory spatial sensitivity of inferior collicular neurons of echolocating bats
    • Schlegel, P.A., Jen, P.H., Singh, S. Auditory spatial sensitivity of inferior collicular neurons of echolocating bats. Brain Res., 1988, 456, 127-138.
    • (1988) Brain Res. , vol.456 , pp. 127-138
    • Schlegel, P.A.1    Jen, P.H.2    Singh, S.3
  • 19
    • 0033565767 scopus 로고    scopus 로고
    • Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior
    • Yang, R.B., Robinson, S.W., Xiong, W.H., Yau, K.W., Birch, D.G., Garbers, D.L. Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior. J. Neurosci., 1999, 19, 5889-5897.
    • (1999) J. Neurosci. , vol.19 , pp. 5889-5897
    • Yang, R.B.1    Robinson, S.W.2    Xiong, W.H.3    Yau, K.W.4    Birch, D.G.5    Garbers, D.L.6
  • 20
    • 0029010703 scopus 로고
    • The C-type natriuretic peptide receptor is the predominant natriuretic peptide receptor mRNA expressed in rat hypothalamus
    • Langub, M.C., Jr., Dolgas, C.M., Watson, R.E., Jr., Herman, J.P. The C-type natriuretic peptide receptor is the predominant natriuretic peptide receptor mRNA expressed in rat hypothalamus. J. Neuroendocrinol., 1995, 7, 305-309.
    • (1995) J. Neuroendocrinol. , vol.7 , pp. 305-309
    • Langub Jr., M.C.1    Dolgas, C.M.2    Watson Jr., R.E.3    Herman, J.P.4
  • 22
    • 0033975341 scopus 로고    scopus 로고
    • Guanylyl cyclase-B represents the predominant natriuretic peptide receptor expressed at exceptionally high levels in the pineal gland
    • Muller, D., Olcese, J., Mukhopadhyay, A.K., Middendorff, R. Guanylyl cyclase-B represents the predominant natriuretic peptide receptor expressed at exceptionally high levels in the pineal gland. Brain Res. Mol. Brain Res., 2000, 75, 321-329.
    • (2000) Brain Res. Mol. Brain Res. , vol.75 , pp. 321-329
    • Muller, D.1    Olcese, J.2    Mukhopadhyay, A.K.3    Middendorff, R.4
  • 23
    • 41149179530 scopus 로고    scopus 로고
    • Degeneration of the olfactory guanylyl cyclase D gene during primate evolution
    • Young, J.M., Waters, H., Dong, C., Fulle, H.J., Liman, E.R. Degeneration of the olfactory guanylyl cyclase D gene during primate evolution. PLoS One, 2007, 2, e884.
    • (2007) PLoS One , vol.2
    • Young, J.M.1    Waters, H.2    Dong, C.3    Fulle, H.J.4    Liman, E.R.5
  • 24
    • 33846365573 scopus 로고    scopus 로고
    • Species differences in the localization of soluble guanylyl cyclase subunits in monkey and rat brain
    • Pifarre, P., Garcia, A., Mengod, G. Species differences in the localization of soluble guanylyl cyclase subunits in monkey and rat brain. J. Comp. Neurol., 2007, 500, 942-957.
    • (2007) J. Comp. Neurol. , vol.500 , pp. 942-957
    • Pifarre, P.1    Garcia, A.2    Mengod, G.3
  • 25
    • 0037290712 scopus 로고    scopus 로고
    • Major occurrence of the new alpha2beta1 isoform of NO-sensitive guanylyl cyclase in brain
    • Mergia, E., Russwurm, M., Zoidl, G., Koesling, D. Major occurrence of the new alpha2beta1 isoform of NO-sensitive guanylyl cyclase in brain. Cell Signal., 2003, 15, 189-195.
    • (2003) Cell Signal. , vol.15 , pp. 189-195
    • Mergia, E.1    Russwurm, M.2    Zoidl, G.3    Koesling, D.4
  • 26
    • 67650376194 scopus 로고    scopus 로고
    • Phosphodiesterase genes and antidepressant treatment response: A review
    • Esposito, K., Reierson, G.W., Luo, H.R., Wu, G.S., Licinio, J., Wong, M.L. Phosphodiesterase genes and antidepressant treatment response: a review. Ann. Med., 2009, 41, 177-185.
    • (2009) Ann. Med. , vol.41 , pp. 177-185
    • Esposito, K.1    Reierson, G.W.2    Luo, H.R.3    Wu, G.S.4    Licinio, J.5    Wong, M.L.6
  • 28
    • 33847689816 scopus 로고    scopus 로고
    • Crystal structures of phosphodiesterases and implications on substrate specificity and inhibitor selectivity
    • Ke, H., Wang, H. Crystal structures of phosphodiesterases and implications on substrate specificity and inhibitor selectivity. Curr. Top. Med. Chem., 2007, 7, 391-403.
    • (2007) Curr. Top. Med. Chem. , vol.7 , pp. 391-403
    • Ke, H.1    Wang, H.2
  • 29
    • 19944432457 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic roles of NO, cGK, and RhoA in longlasting potentiation and aggregation of synaptic proteins
    • Wang, H.G., Lu, F.M., Jin, I., Udo, H., Kandel, E.R., de Vente, J., Walter, U., Lohmann, S.M., Hawkins, R.D., Antonova, I. Presynaptic and postsynaptic roles of NO, cGK, and RhoA in longlasting potentiation and aggregation of synaptic proteins. Neuron, 2005, 45, 389-403.
    • (2005) Neuron , vol.45 , pp. 389-403
    • Wang, H.G.1    Lu, F.M.2    Jin, I.3    Udo, H.4    Kandel, E.R.5    de Vente, J.6    Walter, U.7    Lohmann, S.M.8    Hawkins, R.D.9    Antonova, I.10
  • 31
    • 15744369740 scopus 로고    scopus 로고
    • Structural and functional features in human PDE5A1 regulatory domain that provide for allosteric cGMP binding, dimerization, and regulation
    • Zoraghi, R., Bessay, E.P., Corbin, J.D., Francis, S.H. Structural and functional features in human PDE5A1 regulatory domain that provide for allosteric cGMP binding, dimerization, and regulation. J. Biol. Chem., 2005, 280, 12051-12063.
    • (2005) J. Biol. Chem. , vol.280 , pp. 12051-12063
    • Zoraghi, R.1    Bessay, E.P.2    Corbin, J.D.3    Francis, S.H.4
  • 32
    • 0034801310 scopus 로고    scopus 로고
    • First computational evidence for a catalytic bridging hydroxide ion in a phosphodiesterase active site
    • Zhan, C.G., Zheng, F. First computational evidence for a catalytic bridging hydroxide ion in a phosphodiesterase active site. J. Am. Chem. Soc., 2001, 123, 2835-2838.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 2835-2838
    • Zhan, C.G.1    Zheng, F.2
  • 34
    • 36749006297 scopus 로고    scopus 로고
    • Spatiotemporal control of cAMP signalling processes by anchored signalling complexes
    • Jarnaess, E., Tasken, K. Spatiotemporal control of cAMP signalling processes by anchored signalling complexes. Biochem. Soc. Trans., 2007, 35, 931-937.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 931-937
    • Jarnaess, E.1    Tasken, K.2
  • 35
    • 0035889980 scopus 로고    scopus 로고
    • Expression of cGMP-specific phosphodiesterase 9A mRNA in the rat brain
    • Andreeva, S.G., Dikkes, P., Epstein, P.M., Rosenberg, P.A. Expression of cGMP-specific phosphodiesterase 9A mRNA in the rat brain. J. Neurosci., 2001, 21, 9068-9076.
    • (2001) J. Neurosci. , vol.21 , pp. 9068-9076
    • Andreeva, S.G.1    Dikkes, P.2    Epstein, P.M.3    Rosenberg, P.A.4
  • 37
    • 2342630520 scopus 로고    scopus 로고
    • Species differences in the localization of cGMP-producing and NO-responsive elements in the mouse and rat hippocampus using cGMP immunocytochemistry
    • van Staveren, W.C., Steinbusch, H.W., Markerink-van Ittersum, M., Behrends, S., de Vente, J. Species differences in the localization of cGMP-producing and NO-responsive elements in the mouse and rat hippocampus using cGMP immunocytochemistry. Eur. J. Neurosci., 2004, 19, 2155-2168.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 2155-2168
    • van Staveren, W.C.1    Steinbusch, H.W.2    Markerink-van Ittersum, M.3    Behrends, S.4    de Vente, J.5
  • 38
    • 34249871389 scopus 로고    scopus 로고
    • Expression of the cGMP-specific phosphodiesterases 2 and 9 in normal and Alzheimer's disease human brains
    • Reyes-Irisarri, E., Markerink-Van Ittersum, M., Mengod, G., de Vente, J. Expression of the cGMP-specific phosphodiesterases 2 and 9 in normal and Alzheimer's disease human brains. Eur. J. Neurosci., 2007, 25, 3332-3338.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 3332-3338
    • Reyes-Irisarri, E.1    Markerink-Van Ittersum, M.2    Mengod, G.3    de Vente, J.4
  • 39
    • 0028196632 scopus 로고
    • Expression of a calmodulin-dependent phosphodiesterase isoform (PDE1B1) correlates with brain regions having extensive dopaminergic innervation
    • Polli, J.W., Kincaid, R.L. Expression of a calmodulin-dependent phosphodiesterase isoform (PDE1B1) correlates with brain regions having extensive dopaminergic innervation. J. Neurosci., 1994, 14, 1251-1261.
    • (1994) J. Neurosci. , vol.14 , pp. 1251-1261
    • Polli, J.W.1    Kincaid, R.L.2
  • 40
    • 0028218265 scopus 로고
    • Differential expression of the 61 kDa and 63 kDa calmodulin-dependent phosphodiesterases in the mouse brain
    • Yan, C., Bentley, J.K., Sonnenburg, W.K., Beavo, J.A. Differential expression of the 61 kDa and 63 kDa calmodulin-dependent phosphodiesterases in the mouse brain. J. Neurosci., 1994, 14, 973 984.
    • (1994) J. Neurosci. , vol.14 , pp. 973-984
    • Yan, C.1    Bentley, J.K.2    Sonnenburg, W.K.3    Beavo, J.A.4
  • 41
    • 0029845929 scopus 로고    scopus 로고
    • The calmodulindependent phosphodiesterase gene PDE1C encodes several functionally different splice variants in a tissue-specific manner
    • Yan, C., Zhao, A.Z., Bentley, J.K., Beavo, J.A. The calmodulindependent phosphodiesterase gene PDE1C encodes several functionally different splice variants in a tissue-specific manner. J. Biol. Chem., 1996, 271, 25699-25706.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25699-25706
    • Yan, C.1    Zhao, A.Z.2    Bentley, J.K.3    Beavo, J.A.4
  • 44
    • 0029876116 scopus 로고    scopus 로고
    • Differential cellular pattern of gene expression for two distinct cGMP-inhibited cyclic nucleotide phosphodiesterases in developing and mature rat brain
    • Reinhardt, R.R., Bondy, C.A. Differential cellular pattern of gene expression for two distinct cGMP-inhibited cyclic nucleotide phosphodiesterases in developing and mature rat brain. Neuroscience, 1996, 72, 567-578.
    • (1996) Neuroscience , vol.72 , pp. 567-578
    • Reinhardt, R.R.1    Bondy, C.A.2
  • 46
    • 1642441418 scopus 로고    scopus 로고
    • Striatal phosphodiesterase mRNA and protein levels are reduced in Huntington's disease transgenic mice prior to the onset of motor symptoms
    • Hebb, A.L., Robertson, H.A., Denovan-Wright, E.M. Striatal phosphodiesterase mRNA and protein levels are reduced in Huntington's disease transgenic mice prior to the onset of motor symptoms. Neuroscience, 2004, 123, 967-981.
    • (2004) Neuroscience , vol.123 , pp. 967-981
    • Hebb, A.L.1    Robertson, H.A.2    Denovan-Wright, E.M.3
  • 48
    • 67649387950 scopus 로고    scopus 로고
    • PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system
    • Kruse, L.S., Moller, M., Tibaek, M., Gammeltoft, S., Olesen, J., Kruuse, C. PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system. Brain Res., 2009, 1281, 25-34.
    • (2009) Brain Res. , vol.1281 , pp. 25-34
    • Kruse, L.S.1    Moller, M.2    Tibaek, M.3    Gammeltoft, S.4    Olesen, J.5    Kruuse, C.6
  • 49
    • 22644440012 scopus 로고    scopus 로고
    • 3', 5'-cyclic nucleotide phosphodiesterase 11A: Localization in human tissues
    • Loughney, K., Taylor, J., Florio, V.A. 3', 5'-cyclic nucleotide phosphodiesterase 11A: localization in human tissues. Int. J. Impot. Res., 2005, 17, 320-325.
    • (2005) Int. J. Impot. Res. , vol.17 , pp. 320-325
    • Loughney, K.1    Taylor, J.2    Florio, V.A.3
  • 50
    • 0034033975 scopus 로고    scopus 로고
    • Rising behind NO: CGMP-dependent protein kinases
    • Hofmann, F., Ammendola, A., Schlossmann, J. Rising behind NO: cGMP-dependent protein kinases. J. Cell Sci., 2000, 113 (Pt 10), 1671-1676.
    • (2000) J. Cell Sci. , vol.113 , Issue.PART 10 , pp. 1671-1676
    • Hofmann, F.1    Ammendola, A.2    Schlossmann, J.3
  • 52
    • 0031021491 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase and cellular signaling in the nervous system
    • Wang, X., Robinson, P.J. Cyclic GMP-dependent protein kinase and cellular signaling in the nervous system. J. Neurochem., 1997, 68, 443-456.
    • (1997) J. Neurochem. , vol.68 , pp. 443-456
    • Wang, X.1    Robinson, P.J.2
  • 53
    • 33845575859 scopus 로고    scopus 로고
    • Cyclic GMP metabolism and its role in brain physiology
    • Domek-Lopacinska, K., Strosznajder, J.B. Cyclic GMP metabolism and its role in brain physiology. J. Physiol. Pharmacol., 2005, 56 Suppl 2, 15-34.
    • (2005) J. Physiol. Pharmacol. , Issue.56 SUPPL. 2 , pp. 15-34
    • Domek-Lopacinska, K.1    Strosznajder, J.B.2
  • 54
    • 0029178019 scopus 로고
    • Compartmentalization of cyclic AMP phosphodiesterases, signalling 'crosstalk', desensitization and the phosphorylation of Gi-2 add cell specific personalization to the control of the levels of the second messenger cyclic AMP
    • Houslay, M.D. Compartmentalization of cyclic AMP phosphodiesterases, signalling 'crosstalk', desensitization and the phosphorylation of Gi-2 add cell specific personalization to the control of the levels of the second messenger cyclic AMP. Adv. Enzyme Regul., 1995, 35, 303-338.
    • (1995) Adv. Enzyme Regul. , vol.35 , pp. 303-338
    • Houslay, M.D.1
  • 55
    • 34447265905 scopus 로고    scopus 로고
    • Biochemistry and physiology of cyclic nucleotide phosphodiesterases: Essential components in cyclic nucleotide signaling
    • Conti, M., Beavo, J. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu. Rev. Biochem., 2007, 76, 481-511.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 481-511
    • Conti, M.1    Beavo, J.2
  • 56
    • 0034108626 scopus 로고    scopus 로고
    • Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities
    • Corbin, J.D., Turko, I.V., Beasley, A., Francis, S.H. Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities. Eur. J. Biochem., 2000, 267, 2760-2767.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 2760-2767
    • Corbin, J.D.1    Turko, I.V.2    Beasley, A.3    Francis, S.H.4
  • 57
    • 34250156365 scopus 로고    scopus 로고
    • cAMP and cGMP signaling crosstalk: Role of phosphodiesterases and implications for cardiac pathophysiology
    • Zaccolo, M., Movsesian, M.A. cAMP and cGMP signaling crosstalk: role of phosphodiesterases and implications for cardiac pathophysiology. Circ. Res., 2007, 100, 1569-1578.
    • (2007) Circ. Res. , vol.100 , pp. 1569-1578
    • Zaccolo, M.1    Movsesian, M.A.2
  • 58
    • 0031876627 scopus 로고    scopus 로고
    • Cyclic nucleotide crosstalk and the regulation of cerebral vasodilation
    • Pelligrino, D.A., Wang, Q. Cyclic nucleotide crosstalk and the regulation of cerebral vasodilation. Prog. Neurobiol., 1998, 56, 1-18.
    • (1998) Prog. Neurobiol. , vol.56 , pp. 1-18
    • Pelligrino, D.A.1    Wang, Q.2
  • 59
    • 34249949774 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase and the serotonin transporter get harmonious
    • Garthwaite, J. Neuronal nitric oxide synthase and the serotonin transporter get harmonious. Proc. Natl. Acad. Sci. U. S. A., 2007, 104, 7739-7740.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 7739-7740
    • Garthwaite, J.1
  • 60
    • 33748652508 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterase-mediated integration of cGMP and cAMP signaling in cells of the cardiovascular system
    • Maurice, D.H. Cyclic nucleotide phosphodiesterase-mediated integration of cGMP and cAMP signaling in cells of the cardiovascular system. Front. Biosci., 2005, 10, 1221-1228.
    • (2005) Front. Biosci. , vol.10 , pp. 1221-1228
    • Maurice, D.H.1
  • 61
    • 0035890469 scopus 로고    scopus 로고
    • Activation of phosphodiesterase 5 and inhibition of guanylate cyclase by cGMP-dependent protein kinase in smooth muscle
    • Murthy, K.S. Activation of phosphodiesterase 5 and inhibition of guanylate cyclase by cGMP-dependent protein kinase in smooth muscle. Biochem. J., 2001, 360, 199-208.
    • (2001) Biochem. J. , vol.360 , pp. 199-208
    • Murthy, K.S.1
  • 62
    • 0031565083 scopus 로고    scopus 로고
    • Learning and memory. Never fear, LTP is hear
    • Malenka, R.C., Nicoll, R.A. Learning and memory. Never fear, LTP is hear. Nature, 1997, 390, 552-553.
    • (1997) Nature , vol.390 , pp. 552-553
    • Malenka, R.C.1    Nicoll, R.A.2
  • 63
    • 0024968871 scopus 로고
    • Inescapable versus escapable shock modulates long-term potentiation in the rat hippocampus
    • Shors, T.J., Seib, T.B., Levine, S., Thompson, R.F. Inescapable versus escapable shock modulates long-term potentiation in the rat hippocampus. Science, 1989, 244, 224-226.
    • (1989) Science , vol.244 , pp. 224-226
    • Shors, T.J.1    Seib, T.B.2    Levine, S.3    Thompson, R.F.4
  • 64
    • 10944243551 scopus 로고    scopus 로고
    • Behavioral stress modifies hippocampal synaptic plasticity through corticosterone-induced sustained extracellular signal-regulated kinase/mitogen-activated protein kinase activation
    • Yang, C.H., Huang, C.C., Hsu, K.S. Behavioral stress modifies hippocampal synaptic plasticity through corticosterone-induced sustained extracellular signal-regulated kinase/mitogen-activated protein kinase activation. J. Neurosci., 2004, 24, 11029-11034.
    • (2004) J. Neurosci. , vol.24 , pp. 11029-11034
    • Yang, C.H.1    Huang, C.C.2    Hsu, K.S.3
  • 65
    • 33646095196 scopus 로고    scopus 로고
    • Long-term effects of brief acute stress on cellular signaling and hippocampal LTP
    • Ahmed, T., Frey, J.U., Korz, V. Long-term effects of brief acute stress on cellular signaling and hippocampal LTP. J. Neurosci., 2006, 26, 3951-3958.
    • (2006) J. Neurosci. , vol.26 , pp. 3951-3958
    • Ahmed, T.1    Frey, J.U.2    Korz, V.3
  • 66
    • 0035025194 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation and antidepressive drugs share similar cellular effects in rat hippocampus
    • Levkovitz, Y., Grisaru, N., Segal, M. Transcranial magnetic stimulation and antidepressive drugs share similar cellular effects in rat hippocampus. Neuropsychopharmacology, 2001, 24, 608-616.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 608-616
    • Levkovitz, Y.1    Grisaru, N.2    Segal, M.3
  • 67
    • 0034097163 scopus 로고    scopus 로고
    • Repeated ECS and fluoxetine administration have equivalent effects on hippocampal synaptic plasticity
    • Stewart, C.A., Reid, I.C. Repeated ECS and fluoxetine administration have equivalent effects on hippocampal synaptic plasticity. Psychopharmacology (Berl), 2000, 148, 217-223.
    • (2000) Psychopharmacology (Berl) , vol.148 , pp. 217-223
    • Stewart, C.A.1    Reid, I.C.2
  • 68
    • 33745214865 scopus 로고    scopus 로고
    • Hippocampal neurogenesis: Regulation by stress and antidepressants
    • Dranovsky, A., Hen, R. Hippocampal neurogenesis: regulation by stress and antidepressants. Biol. Psychiatry, 2006, 59, 1136-1143.
    • (2006) Biol. Psychiatry , vol.59 , pp. 1136-1143
    • Dranovsky, A.1    Hen, R.2
  • 69
    • 3242745166 scopus 로고    scopus 로고
    • Depression: A case of neuronal life and death?
    • Duman, R.S. Depression: a case of neuronal life and death? Biol. Psychiatry, 2004, 56, 140-145.
    • (2004) Biol. Psychiatry , vol.56 , pp. 140-145
    • Duman, R.S.1
  • 72
    • 33645109592 scopus 로고    scopus 로고
    • Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment
    • Warner-Schmidt, J.L., Duman, R.S. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus, 2006, 16, 239-249.
    • (2006) Hippocampus , vol.16 , pp. 239-249
    • Warner-Schmidt, J.L.1    Duman, R.S.2
  • 74
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg, J.E., Eisch, A.J., Nestler, E.J., Duman, R.S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci., 2000, 20, 9104-9110.
    • (2000) J. Neurosci. , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 75
    • 79955541008 scopus 로고    scopus 로고
    • Presynaptic nitric oxide/cGMP facilitates glutamate release via hyperpolarization-activated cyclic nucleotide-gated channels in the hippocampus
    • Neitz, A., Mergia, E., Eysel, U.T., Koesling, D., Mittmann, T. Presynaptic nitric oxide/cGMP facilitates glutamate release via hyperpolarization-activated cyclic nucleotide-gated channels in the hippocampus. Eur. J. Neurosci., 2011, 33, 1611-1621.
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 1611-1621
    • Neitz, A.1    Mergia, E.2    Eysel, U.T.3    Koesling, D.4    Mittmann, T.5
  • 76
    • 34447251539 scopus 로고    scopus 로고
    • The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10
    • Wang, H., Robinson, H., Ke, H. The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10. J. Mol. Biol., 2007, 371, 302-307.
    • (2007) J. Mol. Biol. , vol.371 , pp. 302-307
    • Wang, H.1    Robinson, H.2    Ke, H.3
  • 77
    • 55749110026 scopus 로고    scopus 로고
    • A role for cGMP-dependent protein kinase II in AMPA receptor trafficking and synaptic plasticity
    • Serulle, Y., Arancio, O., Ziff, E.B. A role for cGMP-dependent protein kinase II in AMPA receptor trafficking and synaptic plasticity. Channels (Austin), 2008, 2, 230-232.
    • (2008) Channels (Austin) , vol.2 , pp. 230-232
    • Serulle, Y.1    Arancio, O.2    Ziff, E.B.3
  • 79
    • 0037980143 scopus 로고    scopus 로고
    • Synergism between calcium and cyclic GMP in cyclic AMP response element-dependent transcriptional regulation requires cooperation between CREB and C/EBP-beta
    • Chen, Y., Zhuang, S., Cassenaer, S., Casteel, D.E., Gudi, T., Boss, G.R., Pilz, R.B. Synergism between calcium and cyclic GMP in cyclic AMP response element-dependent transcriptional regulation requires cooperation between CREB and C/EBP-beta. Mol. Cell Biol., 2003, 23, 4066-4082.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 4066-4082
    • Chen, Y.1    Zhuang, S.2    Cassenaer, S.3    Casteel, D.E.4    Gudi, T.5    Boss, G.R.6    Pilz, R.B.7
  • 80
    • 0033493229 scopus 로고    scopus 로고
    • Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus
    • Lu, Y.F., Kandel, E.R., Hawkins, R.D. Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus. J. Neurosci., 1999, 19, 10250-10261.
    • (1999) J. Neurosci. , vol.19 , pp. 10250-10261
    • Lu, Y.F.1    Kandel, E.R.2    Hawkins, R.D.3
  • 81
    • 0036715034 scopus 로고    scopus 로고
    • Ryanodine receptors contribute to cGMPinduced late-phase LTP and CREB phosphorylation in the hippocampus
    • Lu, Y.F., Hawkins, R.D. Ryanodine receptors contribute to cGMPinduced late-phase LTP and CREB phosphorylation in the hippocampus. J. Neurophysiol., 2002, 88, 1270-1278.
    • (2002) J. Neurophysiol. , vol.88 , pp. 1270-1278
    • Lu, Y.F.1    Hawkins, R.D.2
  • 82
    • 0036843061 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats
    • Zhang, R., Wang, Y., Zhang, L., Zhang, Z., Tsang, W., Lu, M., Chopp, M. Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke, 2002, 33, 2675 2680.
    • (2002) Stroke , vol.33 , pp. 2675-2680
    • Zhang, R.1    Wang, Y.2    Zhang, L.3    Zhang, Z.4    Tsang, W.5    Lu, M.6    Chopp, M.7
  • 83
    • 0034754052 scopus 로고    scopus 로고
    • A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats
    • Zhang, R., Zhang, L., Zhang, Z., Wang, Y., Lu, M., Lapointe, M., Chopp, M. A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats. Ann. Neurol., 2001, 50, 602-611.
    • (2001) Ann. Neurol. , vol.50 , pp. 602-611
    • Zhang, R.1    Zhang, L.2    Zhang, Z.3    Wang, Y.4    Lu, M.5    Lapointe, M.6    Chopp, M.7
  • 84
    • 24944455102 scopus 로고    scopus 로고
    • Activation of the PI3-K/Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone
    • Wang, L., Gang Zhang, Z., Lan Zhang, R., Chopp, M. Activation of the PI3-K/Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone. J. Cereb. Blood Flow Metab., 2005, 25, 1150-1158.
    • (2005) J. Cereb. Blood Flow Metab. , vol.25 , pp. 1150-1158
    • Wang, L.1    Gang Zhang, Z.2    Lan Zhang, R.3    Chopp, M.4
  • 85
    • 67449135901 scopus 로고    scopus 로고
    • The nitric oxide-cGMP pathway controls the directional polarity of growth cone guidance via modulating cytosolic Ca2+ signals
    • Tojima, T., Itofusa, R., Kamiguchi, H. The nitric oxide-cGMP pathway controls the directional polarity of growth cone guidance via modulating cytosolic Ca2+ signals. J. Neurosci., 2009, 29, 7886-7897.
    • (2009) J. Neurosci. , vol.29 , pp. 7886-7897
    • Tojima, T.1    Itofusa, R.2    Kamiguchi, H.3
  • 87
    • 71849099466 scopus 로고    scopus 로고
    • cAMP-dependent axon guidance is distinctly regulated by Epac and protein kinase A
    • Murray, A.J., Tucker, S.J., Shewan, D.A. cAMP-dependent axon guidance is distinctly regulated by Epac and protein kinase A. J. Neurosci., 2009, 29, 15434-15444.
    • (2009) J. Neurosci. , vol.29 , pp. 15434-15444
    • Murray, A.J.1    Tucker, S.J.2    Shewan, D.A.3
  • 88
    • 75749145003 scopus 로고    scopus 로고
    • Local and long-range reciprocal regulation of cAMP and cGMP in axon/dendrite formation
    • Shelly, M., Lim, B.K., Cancedda, L., Heilshorn, S.C., Gao, H., Poo, M.M. Local and long-range reciprocal regulation of cAMP and cGMP in axon/dendrite formation. Science, 2010, 327, 547-552.
    • (2010) Science , vol.327 , pp. 547-552
    • Shelly, M.1    Lim, B.K.2    Cancedda, L.3    Heilshorn, S.C.4    Gao, H.5    Poo, M.M.6
  • 89
    • 2442650231 scopus 로고    scopus 로고
    • Adenosine receptor, protein kinase G, and p38 mitogenactivated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation
    • Zhu, C.B., Hewlett, W.A., Feoktistov, I., Biaggioni, I., Blakely, R.D. Adenosine receptor, protein kinase G, and p38 mitogenactivated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation. Mol. Pharmacol., 2004, 65, 1462-1474.
    • (2004) Mol. Pharmacol. , vol.65 , pp. 1462-1474
    • Zhu, C.B.1    Hewlett, W.A.2    Feoktistov, I.3    Biaggioni, I.4    Blakely, R.D.5
  • 91
    • 0036024257 scopus 로고    scopus 로고
    • Allelic association of the neuronal nitric oxide synthase (NOS1) gene with schizophrenia
    • Shinkai, T., Ohmori, O., Hori, H., Nakamura, J. Allelic association of the neuronal nitric oxide synthase (NOS1) gene with schizophrenia. Mol. Psychiatry, 2002, 7, 560-563.
    • (2002) Mol. Psychiatry , vol.7 , pp. 560-563
    • Shinkai, T.1    Ohmori, O.2    Hori, H.3    Nakamura, J.4
  • 92
    • 72049121241 scopus 로고    scopus 로고
    • Genetic association analysis of functional polymorphisms in neuronal nitric oxide synthase 1 gene (NOS1) and mood disorders and fluvoxamine response in major depressive disorder in the Japanese population
    • Okumura, T., Kishi, T., Okochi, T., Ikeda, M., Kitajima, T., Yamanouchi, Y., Kinoshita, Y., Kawashima, K., Tsunoka, T., Inada, T., Ozaki, N., Iwata, N. Genetic association analysis of functional polymorphisms in neuronal nitric oxide synthase 1 gene (NOS1) and mood disorders and fluvoxamine response in major depressive disorder in the Japanese population. Neuropsychobiology, 2010, 61, 57-63.
    • (2010) Neuropsychobiology , vol.61 , pp. 57-63
    • Okumura, T.1    Kishi, T.2    Okochi, T.3    Ikeda, M.4    Kitajima, T.5    Yamanouchi, Y.6    Kinoshita, Y.7    Kawashima, K.8    Tsunoka, T.9    Inada, T.10    Ozaki, N.11    Iwata, N.12
  • 95
    • 62349140796 scopus 로고    scopus 로고
    • Association study of phosphodiesterase genes in the Sequenced Treatment Alternatives to Relieve Depression sample
    • Cabanero, M., Laje, G., Detera-Wadleigh, S., McMahon, F.J. Association study of phosphodiesterase genes in the Sequenced Treatment Alternatives to Relieve Depression sample. Pharmacogenet. Genom., 2009, 19, 235-238.
    • (2009) Pharmacogenet. Genom. , vol.19 , pp. 235-238
    • Cabanero, M.1    Laje, G.2    Detera-Wadleigh, S.3    McMahon, F.J.4
  • 96
    • 77952654152 scopus 로고    scopus 로고
    • Phosphodiesterase signaling system is disrupted in the cerebella of subjects with schizophrenia, bipolar disorder, and major depression
    • Fatemi, S.H., Folsom, T.D., Reutiman, T.J., Vazquez, G. Phosphodiesterase signaling system is disrupted in the cerebella of subjects with schizophrenia, bipolar disorder, and major depression. Schizophr. Res., 2010, 119, 266-267.
    • (2010) Schizophr. Res. , vol.119 , pp. 266-267
    • Fatemi, S.H.1    Folsom, T.D.2    Reutiman, T.J.3    Vazquez, G.4
  • 97
    • 77249132263 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase alteration accounts for the role of 5-HT1A receptor in modulating anxiety-related behaviors
    • Zhang, J., Huang, X.Y., Ye, M.L., Luo, C.X., Wu, H.Y., Hu, Y., Zhou, Q.G., Wu, D.L., Zhu, L.J., Zhu, D.Y. Neuronal nitric oxide synthase alteration accounts for the role of 5-HT1A receptor in modulating anxiety-related behaviors. J. Neurosci., 2010, 30, 2433-2441.
    • (2010) J. Neurosci. , vol.30 , pp. 2433-2441
    • Zhang, J.1    Huang, X.Y.2    Ye, M.L.3    Luo, C.X.4    Wu, H.Y.5    Hu, Y.6    Zhou, Q.G.7    Wu, D.L.8    Zhu, L.J.9    Zhu, D.Y.10
  • 99
    • 58749098210 scopus 로고    scopus 로고
    • Development and persistence of long-lasting behavioral sensitization to cocaine in female mice: Role of the nNOS gene
    • Balda, M.A., Anderson, K.L., Itzhak, Y. Development and persistence of long-lasting behavioral sensitization to cocaine in female mice: role of the nNOS gene. Neuropharmacology, 2009, 56, 709-715.
    • (2009) Neuropharmacology , vol.56 , pp. 709-715
    • Balda, M.A.1    Anderson, K.L.2    Itzhak, Y.3
  • 102
    • 33846564027 scopus 로고    scopus 로고
    • Long-term potentiation in the visual cortex requires both nitric oxide receptor guanylyl cyclases
    • Haghikia, A., Mergia, E., Friebe, A., Eysel, U.T., Koesling, D., Mittmann, T. Long-term potentiation in the visual cortex requires both nitric oxide receptor guanylyl cyclases. J. Neurosci., 2007, 27, 818-823.
    • (2007) J. Neurosci. , vol.27 , pp. 818-823
    • Haghikia, A.1    Mergia, E.2    Friebe, A.3    Eysel, U.T.4    Koesling, D.5    Mittmann, T.6
  • 103
    • 34547184647 scopus 로고    scopus 로고
    • Behavioral and neurochemical characterization of mice deficient in the phosphodiesterase-1B (PDE1B) enzyme
    • Siuciak, J.A., McCarthy, S.A., Chapin, D.S., Reed, T.M., Vorhees, C.V., Repaske, D.R. Behavioral and neurochemical characterization of mice deficient in the phosphodiesterase-1B (PDE1B) enzyme. Neuropharmacology, 2007, 53, 113-124.
    • (2007) Neuropharmacology , vol.53 , pp. 113-124
    • Siuciak, J.A.1    McCarthy, S.A.2    Chapin, D.S.3    Reed, T.M.4    Vorhees, C.V.5    Repaske, D.R.6
  • 104
    • 0037096253 scopus 로고    scopus 로고
    • Phosphodiesterase 1B knock-out mice exhibit exaggerated locomotor hyperactivity and DARPP-32 phosphorylation in response to dopamine agonists and display impaired spatial learning
    • Reed, T.M., Repaske, D.R., Snyder, G.L., Greengard, P., Vorhees, C.V. Phosphodiesterase 1B knock-out mice exhibit exaggerated locomotor hyperactivity and DARPP-32 phosphorylation in response to dopamine agonists and display impaired spatial learning. J. Neurosci., 2002, 22, 5188-5197.
    • (2002) J. Neurosci. , vol.22 , pp. 5188-5197
    • Reed, T.M.1    Repaske, D.R.2    Snyder, G.L.3    Greengard, P.4    Vorhees, C.V.5
  • 105
    • 33748851504 scopus 로고    scopus 로고
    • Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: Evidence from PDE1BDARPP32 double-knockout mice
    • Ehrman, L.A., Williams, M.T., Schaefer, T.L., Gudelsky, G.A., Reed, T.M., Fienberg, A.A., Greengard, P., Vorhees, C.V. Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1BDARPP32 double-knockout mice. Genes Brain Behav., 2006, 5, 540-551.
    • (2006) Genes Brain Behav. , vol.5 , pp. 540-551
    • Ehrman, L.A.1    Williams, M.T.2    Schaefer, T.L.3    Gudelsky, G.A.4    Reed, T.M.5    Fienberg, A.A.6    Greengard, P.7    Vorhees, C.V.8
  • 106
    • 38149121389 scopus 로고    scopus 로고
    • Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background
    • Siuciak, J.A., McCarthy, S.A., Chapin, D.S., Martin, A.N., Harms, J.F., Schmidt, C.J. Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background. Neuropharmacology, 2008, 54, 417-427.
    • (2008) Neuropharmacology , vol.54 , pp. 417-427
    • Siuciak, J.A.1    McCarthy, S.A.2    Chapin, D.S.3    Martin, A.N.4    Harms, J.F.5    Schmidt, C.J.6
  • 108
    • 10944220561 scopus 로고    scopus 로고
    • Importance of NO/cGMP signalling via cGMP-dependent protein kinase II for controlling emotionality and neurobehavioural effects of alcohol
    • Werner, C., Raivich, G., Cowen, M., Strekalova, T., Sillaber, I., Buters, J.T., Spanagel, R., Hofmann, F. Importance of NO/cGMP signalling via cGMP-dependent protein kinase II for controlling emotionality and neurobehavioural effects of alcohol. Eur. J. Neurosci., 2004, 20, 3498-3506.
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 3498-3506
    • Werner, C.1    Raivich, G.2    Cowen, M.3    Strekalova, T.4    Sillaber, I.5    Buters, J.T.6    Spanagel, R.7    Hofmann, F.8
  • 109
    • 33645103130 scopus 로고    scopus 로고
    • Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects
    • Joca, S.R., Guimaraes, F.S. Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects. Psychopharmacology (Berl), 2006, 185, 298-305.
    • (2006) Psychopharmacology (Berl) , vol.185 , pp. 298-305
    • Joca, S.R.1    Guimaraes, F.S.2
  • 110
    • 48749127299 scopus 로고    scopus 로고
    • Neuronal NOS inhibitor 1-(2-trifluoromethylphenyl) imidazole augment the effects of antidepressants acting via serotonergic system in the forced swimming test in rats
    • Ulak, G., Mutlu, O., Akar, F.Y., Komsuoglu, F.I., Tanyeri, P., Erden, B.F. Neuronal NOS inhibitor 1-(2-trifluoromethylphenyl) imidazole augment the effects of antidepressants acting via serotonergic system in the forced swimming test in rats. Pharmacol. Biochem. Behav., 2008, 90, 563-568.
    • (2008) Pharmacol. Biochem. Behav. , vol.90 , pp. 563-568
    • Ulak, G.1    Mutlu, O.2    Akar, F.Y.3    Komsuoglu, F.I.4    Tanyeri, P.5    Erden, B.F.6
  • 111
    • 36249009890 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis
    • Zhou, Q.G., Hu, Y., Hua, Y., Hu, M., Luo, C.X., Han, X., Zhu, X.J., Wang, B., Xu, J.S., Zhu, D.Y. Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis. J. Neurochem., 2007, 103, 1843-1854.
    • (2007) J. Neurochem. , vol.103 , pp. 1843-1854
    • Zhou, Q.G.1    Hu, Y.2    Hua, Y.3    Hu, M.4    Luo, C.X.5    Han, X.6    Zhu, X.J.7    Wang, B.8    Xu, J.S.9    Zhu, D.Y.10
  • 113
    • 0346733116 scopus 로고    scopus 로고
    • Augmentation of the NO-cGMP cascade induces anxiogenic-like effect in mice
    • Volke, V., Wegener, G., Vasar, E. Augmentation of the NO-cGMP cascade induces anxiogenic-like effect in mice. J. Physiol. Pharmacol., 2003, 54, 653-660.
    • (2003) J. Physiol. Pharmacol. , vol.54 , pp. 653-660
    • Volke, V.1    Wegener, G.2    Vasar, E.3
  • 114
  • 115
    • 25844498636 scopus 로고    scopus 로고
    • Involvement of nitric oxide-cGMP pathway in the antidepressantlike effects of adenosine in the forced swimming test
    • Kaster, M.P., Rosa, A.O., Santos, A.R., Rodrigues, A.L. Involvement of nitric oxide-cGMP pathway in the antidepressantlike effects of adenosine in the forced swimming test. Int. J. Neuropsychopharmacol., 2005, 8, 601-606.
    • (2005) Int. J. Neuropsychopharmacol. , vol.8 , pp. 601-606
    • Kaster, M.P.1    Rosa, A.O.2    Santos, A.R.3    Rodrigues, A.L.4
  • 116
    • 34250895550 scopus 로고    scopus 로고
    • Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor
    • Dhir, A., Kulkarni, S.K. Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor. Eur. J. Pharmacol., 2007, 568, 177-185.
    • (2007) Eur. J. Pharmacol. , vol.568 , pp. 177-185
    • Dhir, A.1    Kulkarni, S.K.2
  • 117
    • 37749000760 scopus 로고    scopus 로고
    • Appearance of antidepressant-like effect by sildenafil in rats after central muscarinic receptor blockade: Evidence from behavioural and neuro-receptor studies
    • Brink, C.B., Clapton, J.D., Eagar, B.E., Harvey, B.H. Appearance of antidepressant-like effect by sildenafil in rats after central muscarinic receptor blockade: evidence from behavioural and neuro-receptor studies. J. Neural. Transm., 2008, 115, 117-125.
    • (2008) J. Neural. Transm. , vol.115 , pp. 117-125
    • Brink, C.B.1    Clapton, J.D.2    Eagar, B.E.3    Harvey, B.H.4
  • 119
    • 47949118698 scopus 로고    scopus 로고
    • Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice
    • Masood, A., Nadeem, A., Mustafa, S.J., O'Donnell, J.M. Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice. J. Pharmacol. Exp. Ther., 2008, 326, 369-379.
    • (2008) J. Pharmacol. Exp. Ther. , vol.326 , pp. 369-379
    • Masood, A.1    Nadeem, A.2    Mustafa, S.J.3    O'Donnell, J.M.4
  • 120
    • 34249683823 scopus 로고    scopus 로고
    • Recent developments in nitric oxide donor drugs
    • Miller, M.R., Megson, I.L. Recent developments in nitric oxide donor drugs. Br. J. Pharmacol., 2007, 151, 305-321.
    • (2007) Br. J. Pharmacol. , vol.151 , pp. 305-321
    • Miller, M.R.1    Megson, I.L.2
  • 121
    • 69549120287 scopus 로고    scopus 로고
    • Riociguat, an oral soluble guanylate cyclase stimulator for the treatment of pulmonary hypertension
    • Belik, J. Riociguat, an oral soluble guanylate cyclase stimulator for the treatment of pulmonary hypertension. Curr. Opin. Investig. Drugs, 2009, 10, 971-979.
    • (2009) Curr. Opin. Investig. Drugs , vol.10 , pp. 971-979
    • Belik, J.1
  • 122
    • 70449519147 scopus 로고    scopus 로고
    • Role of guanylate cyclase modulators in decompensated heart failure
    • Mitrovic, V., Hernandez, A.F., Meyer, M., Gheorghiade, M. Role of guanylate cyclase modulators in decompensated heart failure. Heart Fail. Rev., 2009, 14, 309-319.
    • (2009) Heart Fail. Rev. , vol.14 , pp. 309-319
    • Mitrovic, V.1    Hernandez, A.F.2    Meyer, M.3    Gheorghiade, M.4
  • 123
    • 31144433061 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
    • Lugnier, C. Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents. Pharmacol. Ther., 2006, 109, 366-398.
    • (2006) Pharmacol. Ther. , vol.109 , pp. 366-398
    • Lugnier, C.1
  • 124
    • 33748686575 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use
    • Bender, A.T., Beavo, J.A. Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol. Rev., 2006, 58, 488-520.
    • (2006) Pharmacol. Rev. , vol.58 , pp. 488-520
    • Bender, A.T.1    Beavo, J.A.2
  • 125
    • 0028357051 scopus 로고
    • Anagrelide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of thrombocythaemia
    • Spencer, C.M., Brogden, R.N. Anagrelide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of thrombocythaemia. Drugs, 1994, 47, 809-822.
    • (1994) Drugs , vol.47 , pp. 809-822
    • Spencer, C.M.1    Brogden, R.N.2
  • 127
    • 2442649996 scopus 로고    scopus 로고
    • A rational approach for the treatment of acute heart failure: Current strategies and future options
    • Sharma, M., Teerlink, J.R. A rational approach for the treatment of acute heart failure: current strategies and future options. Curr. Opin. Cardiol., 2004, 19, 254-263.
    • (2004) Curr. Opin. Cardiol. , vol.19 , pp. 254-263
    • Sharma, M.1    Teerlink, J.R.2
  • 128
    • 34247366877 scopus 로고    scopus 로고
    • Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation
    • Chen, R.W., Williams, A.J., Liao, Z., Yao, C., Tortella, F.C., Dave, J.R. Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation. Neurosci. Lett., 2007, 418, 165-169.
    • (2007) Neurosci. Lett. , vol.418 , pp. 165-169
    • Chen, R.W.1    Williams, A.J.2    Liao, Z.3    Yao, C.4    Tortella, F.C.5    Dave, J.R.6
  • 129
    • 0032428991 scopus 로고    scopus 로고
    • Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction
    • Goldenberg, M.M. Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction. Clin. Ther., 1998, 20, 1033 1048.
    • (1998) Clin. Ther. , vol.20 , pp. 1033-1048
    • Goldenberg, M.M.1
  • 130
    • 0346461630 scopus 로고    scopus 로고
    • Glutamate and depression: Clinical and preclinical studies
    • Paul, I.A., Skolnick, P. Glutamate and depression: clinical and preclinical studies. Ann. N. Y. Acad. Sci., 2003, 1003, 250-272.
    • (2003) Ann. N. Y. Acad. Sci. , vol.1003 , pp. 250-272
    • Paul, I.A.1    Skolnick, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.