Behavioral and neurochemical characterization of mice deficient in the phosphodiesterase-1B (PDE1B) enzyme

Neuropharmacology

Volumn 53, Issue 1, 2007, Pages 113-124

  Siuciak, J A ^a   McCarthy, S A ^a   Chapin, D S ^a   Reed, T M ^b   Vorhees, C V ^c   Repaske, D R ^c  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b College of Mount Saint Joseph ^*  (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Dopamine; Knockout; Mouse; Phosphodiesterase; Serotonin; Striatum

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; AMPHETAMINE; BRAIN MONOAMINE; DIZOCILPINE; DOPAMINE; HOMOVANILLIC ACID; METHAMPHETAMINE; PHENCYCLIDINE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE IB; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; AVOIDANCE BEHAVIOR; COGNITION; CONTROLLED STUDY; CORPUS STRIATUM; DEPRESSION; ENZYME DEFICIENCY; EXPLORATORY BEHAVIOR; FEMALE; FORCED SWIMMING TEST; HOT PLATE TEST; KNOCKOUT MOUSE; LOCOMOTION; MALE; MAZE TEST; MOTOR ACTIVITY; MOUSE; NEUROCHEMISTRY; NOCICEPTION; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; TASK PERFORMANCE; WILD TYPE;

ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BIOGENIC MONOAMINES; BRAIN CHEMISTRY; CENTRAL NERVOUS SYSTEM STIMULANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; PHENCYCLIDINE; PHOSPHORIC DIESTER HYDROLASES; SEX FACTORS; SWIMMING;

EID: 34547184647     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2007.04.009     Document Type: Article

References (31)

1. Bender A.T., and Beavo J.A. Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol. Rev. 58 (2006) 488-520
2. Borisy F.F., Ronnett G.V., Cunningham A.M., Juilfs D., Beavo J., and Snyder S.H. Calcium/calmodulin-activated phosphodiesterase expressed in olfactory receptor neurons. J. Neurosci. 12 (1992) 915-923
3. Cryan J.F., Valentino R.J., and Lucki I. Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci. Biobehav. Rev. 29 (2005) 547-569
4. Ehrman L.A., Williams M.T., Schaefer T.L., Gudelsky G.A., Reed T.M., Fienberg A.A., Greengard P., and Vorhees C.V. Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARP32 double-knockout mice. Genes Brain Behav. 5 (2006) 540-551
5. French E.D., and Ceci A. Non-competitive N-methyl-D-aspartate antagonists are potent activators of ventral tegmental A10 dopamine neurons. Neurosci. Lett. 119 (1990) 159-162
6. Furuyama T., Iwahashi Y., Tano Y., Takagi H., and Inagaki S. Localization of 63-kDa calmodulin-stimulated phosphodiesterase mRNA in the rat brain by in situ hybridization histochemistry. Brain Res. Mol. Brain Res. 26 (1994) 331-336
7. Groenink L., van Bogaert M.J., van der Gugten J., Oosting R.S., and Olivier B. 5-HT1A receptor and 5-HT1B receptor knockout mice in stress and anxiety paradigms. Behav. Pharmacol. 14 (2003) 369-383
8. Irwin S. Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacol. 13 (1968) 222-257
9. Kuczenski R., Segal D.S., Cho A.K., and Melega W. Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. J. Neurosci. 15 (1995) 1308-1317
10. MacQueen G.M., Ramakrishnan K., Croll S.D., Siuciak J.A., Yu G., Young L.T., and Fahnestock M. Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression. Behav. Neurosci. 115 (2001) 1145-1153
11. Maj J., Rogoz Z., and Skuza G. Locomotor hyperactivity induced by MK-801 in rats. Pol. J. Pharmacol. Pharm. 43 (1991) 449-458
12. Melega W.P., Williams A.E., Schmitz D.A., DiStefano E.W., and Cho A.K. Pharmacokinetic and pharmacodynamic analysis of the actions of D-amphetamine and D-methamphetamine on the dopamine terminal. J. Pharmacol. Exp. Ther. 274 (1995) 90-96
13. Missale C., Fiorentini C., Busi C., Collo G., and Spano P.F. The NMDA/D1 receptor complex as a new target in drug development. Curr. Top. Med. Chem. 6 (2006) 801-808
14. Murase S., Mathe J.M., Grenhoff J., and Svensson T.H. Effects of dizocilpine (MK-801) on rat midbrain dopamine cell activity: differential actions on firing pattern related to anatomical localization. J. Neural Transm. 91 (1993) 13-25
15. Polli J., and Kincaid R.L. Molecular cloning of DNA encoding a calmodulin-dependent phosphodiesterase enriched in striatum. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 11079-11083
16. Polli J., and Kincaid R.L. Expression of a calmodulin-dependent phosphodiesterase isoform (PDE1B) correlates with brain regions having extensive dopaminergic innervation. J. Neurosci. 14 (1994) 1251-1261
17. Rao T.S., Kim H.S., Lehmann J., Martin L.L., and Wood P.L. Interactions of phencyclidine receptor agonist MK-801 with dopaminergic system: regional studies in the rat. J. Neurochem. 54 (1990) 1157-1162
18. Reed T.M., Repaske D.R., Snyder G.L., Greengard P., and Vorhees C.V. Phosphodiesterase 1B knockout mice exhibit exaggerated locomotor hyperactivity and DARPP-32 phosphorylation in response to dopamine agonists and display impaired spatial learning. J. Neurosci. 22 (2002) 5188-5197
19. Repaske D.R., Corbin J.G., Conti M., and Goy M.F. A cyclic GMP-stimulated cyclic nucleotide phosphodiesterase gene is highly expressed in the limbic system of the rat brain. Neuroscience 56 (1993) 673-686
20. Shoblock J.R., Sullivan E.B., Maisonneuve I.M., and Glick S.D. Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats. Psychopharmacology (Berl.) 165 (2003) 359-369
21. Shoblock J.R., Maisonneuve I.M., and Glick S.D. Differential interactions of desipramine with amphetamine and methamphetamine: evidence that amphetamine releases dopamine from noradrenergic neurons in the medial prefrontal cortex. Neurochem. Res. 29 (2004) 1437-1442
22. Siuciak J.A., and Fujiwara R.A. The activity of pramipexole in the mouse forced swim test is mediated by D2 rather than D3 receptors. Psychopharmacology 175 (2004) 163-169
23. Siuciak J.A., and Strick C.A. Treating neuropsychiatric disorders with PDE10A inhibitors. Drug Discov. Today Ther. Strategies 3 (2006) 527-532
24. Siuciak J.A., Altar C.A., Wiegand S.J., and Lindsay R.M. Antinociceptive effect of brain-derived neurotrophic factor and neurotrophin-3. Brain Res. 633 (1994) 326-330
25. Siuciak J.A., McCarthy S.A., Chapin D.S., Fujiwara R.A., James L.C., Williams R.D., Stock J.L., McNeish J.D., Strick C.A., Menniti F.S., and Schmidt C.J. Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: evidence for altered striatal function. Neuropharmacology 51 (2006) 374-385
26. Soderling S.H., and Beavo J.A. Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. Curr. Opin. Cell Biol. 12 (2000) 174-179
27. Wadenberg M.L., and Hicks P.B. The conditioned avoidance response test re-evaluated: is it a sensitive test for the detection of potentially atypical antipsychotics?. Neurosci. Biobehav. Rev. 23 (1999) 851-862
28. Yamashita N., Miyashiro M., Baba J., and Sawa A. Rolipram, a selective inhibitor of phosphodiesterase type 4, pronouncedly enhanced the forskolin-induced promotion of dopamine biosynthesis in primary cultured rat mesencephalic neurons. Jpn. J. Pharmacol. 75 (1997) 91-95
29. Yan C., Bentley J.K., Sonnenburg W.K., and Beavo J.A. Differential expression of the 61 kDa and 63 kDa calmodulin-dependent phosphodiesterases in the mouse brain. J. Neurosci. 14 (1994) 973-984
30. Yan C., Zhao A.Z., Bentley J.K., Loughney K., Ferguson K., and Beavo J.A. Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 9677-9681
31. Yan C., Zhao A.Z., Bentley J.K., and Beavo J.A. The calmodulin-dependent phosphodiesterase gene PDE1C encodes several functionally different splice variants in a tissue-specific manner. J. Biol. Chem. 271 (1996) 25699-25706