Heterotrimeric Gi/Go proteins modulate endothelial TLR signaling independent of the MyD88-dependent pathway

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 6, 2011, Pages 2246-2253

  Dauphinee, Shauna M ^a,b   Voelcker, Verena ^a   Tebaykina, Zinaida ^a   Wong, Fred ^b   Karsan, Aly ^a,b  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Heterotrimeric G proteins; Innate immunity; Lipopolysaccharide; Myeloid differentiation factor; Toll like receptors

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INTERFERON; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; PERTUSSIS TOXIN; PROTEIN GO; PROTEIN KINASE B; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; GNAI2 PROTEIN, HUMAN; LIPOPOLYSACCHARIDE; MYD88 PROTEIN, HUMAN; POLYINOSINIC POLYCYTIDYLIC ACID; TLR2 PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ARTICLE; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INNATE IMMUNITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; CELL CULTURE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; METABOLISM; REPORTER GENE; RNA INTERFERENCE; TIME; UMBILICAL VEIN ENDOTHELIAL CELL;

CELLS, CULTURED; ENZYME ACTIVATION; GENES, REPORTER; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASES; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; POLY I-C; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TRANSFECTION;

EID: 82855176950     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01194.2010     Document Type: Article

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