-
1
-
-
68849095682
-
-
Kochanek, K.D., and Hudson, B.L. 1995. Advance report of final mortality statistics, 1992. In Monthly Vital Statistics Report. 43, no. 6 [supplement]. Center for Disease Control & Prevention/National Center for Health Statistics. Hyattsville, Maryland, USA. http://www.cdc.gov/nchs/ PRESSROOM/95facts/fs-436s.htm.
-
Kochanek, K.D., and Hudson, B.L. 1995. Advance report of final mortality statistics, 1992. In Monthly Vital Statistics Report. Vol. 43, no. 6 [supplement]. Center for Disease Control & Prevention/National Center for Health Statistics. Hyattsville, Maryland, USA. http://www.cdc.gov/nchs/ PRESSROOM/95facts/fs-436s.htm.
-
-
-
-
2
-
-
0026048714
-
The pathogenesis of sepsis
-
Bone, R.C. 1991. The pathogenesis of sepsis. Ann. Intern. Med. 115:457-469.
-
(1991)
Ann. Intern. Med
, vol.115
, pp. 457-469
-
-
Bone, R.C.1
-
3
-
-
0026761609
-
Endotoxin, septic shock and acute lung injury: Neutrophils, macrophages and inflammatory mediators
-
Welbourn, C.R., and Young, Y. 1992. Endotoxin, septic shock and acute lung injury: neutrophils, macrophages and inflammatory mediators. Br. J. Surg. 79:998-1003.
-
(1992)
Br. J. Surg
, vol.79
, pp. 998-1003
-
-
Welbourn, C.R.1
Young, Y.2
-
4
-
-
38549180598
-
The immunology of sepsis
-
Sriskandan, S., and Altmann, D. 2008. The immunology of sepsis. J. Pathol. 214:211-223.
-
(2008)
J. Pathol
, vol.214
, pp. 211-223
-
-
Sriskandan, S.1
Altmann, D.2
-
6
-
-
0034307339
-
The Toll receptor family and microbial recognition
-
Medzhitov, R., and Janeway, C., Jr. 2000. The Toll receptor family and microbial recognition. Trends Microbiol. 8:452-456.
-
(2000)
Trends Microbiol
, vol.8
, pp. 452-456
-
-
Medzhitov, R.1
Janeway Jr., C.2
-
7
-
-
0034529119
-
Lipopolysaccharide-induced cytokine and receptor expression and neutrophil infiltration in the liver of osteopetrosis (op/op) mutant mice
-
Jiang, S., et al. 2000. Lipopolysaccharide-induced cytokine and receptor expression and neutrophil infiltration in the liver of osteopetrosis (op/op) mutant mice. Liver. 20:465-474.
-
(2000)
Liver
, vol.20
, pp. 465-474
-
-
Jiang, S.1
-
8
-
-
33751555738
-
The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands
-
Mullaly, S.C., and Kubes, P. 2006. The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands. J. Immunol. 177:8154-8163.
-
(2006)
J. Immunol
, vol.177
, pp. 8154-8163
-
-
Mullaly, S.C.1
Kubes, P.2
-
9
-
-
0035164253
-
Regulation of Toll-like receptors in human monocytes and dendritic cells
-
Visintin, A., et al. 2001. Regulation of Toll-like receptors in human monocytes and dendritic cells. J. Immunol. 166:249-255.
-
(2001)
J. Immunol
, vol.166
, pp. 249-255
-
-
Visintin, A.1
-
10
-
-
0034123135
-
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
-
Muzio, M., et al. 2000. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J. Immunol. 164:5998-6004.
-
(2000)
J. Immunol
, vol.164
, pp. 5998-6004
-
-
Muzio, M.1
-
11
-
-
0036569658
-
Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: A critical role for monocytes in leukocyte lipopolysaccharide responses
-
Sabroe, I., Jones, E.C., Usher, L.R., Whyte, M.K., and Dower, S.K. 2002. Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses. J. Immunol. 168:4701-4710.
-
(2002)
J. Immunol
, vol.168
, pp. 4701-4710
-
-
Sabroe, I.1
Jones, E.C.2
Usher, L.R.3
Whyte, M.K.4
Dower, S.K.5
-
12
-
-
0141781232
-
TLR signaling at the intestinal epithelial interface
-
Abreu, M.T., et al. 2003. TLR signaling at the intestinal epithelial interface. J. Endotoxin. Res. 9:322-330.
-
(2003)
J. Endotoxin. Res
, vol.9
, pp. 322-330
-
-
Abreu, M.T.1
-
13
-
-
0037380645
-
Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs
-
Andonegui, G., et al. 2003. Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J. Clin. Invest. 111:1011-1020.
-
(2003)
J. Clin. Invest
, vol.111
, pp. 1011-1020
-
-
Andonegui, G.1
-
14
-
-
32844469977
-
Lipopolysaccharide signaling in endothelial cells
-
Dauphinee, S.M., and Karsan, A. 2006. Lipopolysaccharide signaling in endothelial cells. Lab Invest. 86:9-22.
-
(2006)
Lab Invest
, vol.86
, pp. 9-22
-
-
Dauphinee, S.M.1
Karsan, A.2
-
15
-
-
24944587964
-
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
-
De Palma, M., et al. 2005. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell. 8:211-226.
-
(2005)
Cancer Cell
, vol.8
, pp. 211-226
-
-
De Palma, M.1
-
16
-
-
0029825455
-
Distinct phenotype of E-selectin-deficient mice. E-selectin is required for slow leukocyte rolling in vivo
-
Kunkel, E.J., and Ley, K. 1996. Distinct phenotype of E-selectin-deficient mice. E-selectin is required for slow leukocyte rolling in vivo. Circ. Res. 79:1196-1204.
-
(1996)
Circ. Res
, vol.79
, pp. 1196-1204
-
-
Kunkel, E.J.1
Ley, K.2
-
17
-
-
0037103165
-
Lipopolysaccharide- induced leukocyte-endothelial cell interactions: A role for CD14 versus toll-like receptor 4 within microvessels
-
Andonegui, G., Goyert, S.M., and Kubes, P. 2002. Lipopolysaccharide- induced leukocyte-endothelial cell interactions: a role for CD14 versus toll-like receptor 4 within microvessels. J. Immunol. 169:2111-2119.
-
(2002)
J. Immunol
, vol.169
, pp. 2111-2119
-
-
Andonegui, G.1
Goyert, S.M.2
Kubes, P.3
-
18
-
-
0031280101
-
Differential roles of selectins and the alpha4-integrin in acute, subacute, and chronic leukocyte recruitment in vivo
-
Johnston, B., et al. 1997. Differential roles of selectins and the alpha4-integrin in acute, subacute, and chronic leukocyte recruitment in vivo. J. Immunol. 159:4514-4523.
-
(1997)
J. Immunol
, vol.159
, pp. 4514-4523
-
-
Johnston, B.1
-
19
-
-
0031010858
-
A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature
-
Wong, J., et al. 1997. A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature. J. Clin. Invest. 99:2782-2790.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 2782-2790
-
-
Wong, J.1
-
20
-
-
34547728312
-
Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior
-
Auffray, C., et al. 2007. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science. 317:666-670.
-
(2007)
Science
, vol.317
, pp. 666-670
-
-
Auffray, C.1
-
21
-
-
0037963473
-
Blood monocytes consist of two principal subsets with distinct migratory properties
-
Geissmann, F., Jung, S., and Littman, D.R. 2003. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity. 19:71-82.
-
(2003)
Immunity
, vol.19
, pp. 71-82
-
-
Geissmann, F.1
Jung, S.2
Littman, D.R.3
-
22
-
-
33846086541
-
New and emerging roles for mast cells in host defence
-
Dawicki, W., and Marshall, J.S. 2007. New and emerging roles for mast cells in host defence. Curr. Opin. Immunol. 19:31-38.
-
(2007)
Curr. Opin. Immunol
, vol.19
, pp. 31-38
-
-
Dawicki, W.1
Marshall, J.S.2
-
23
-
-
33846798106
-
Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
-
Aird, W.C. 2007. Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ. Res. 100:158-173.
-
(2007)
Circ. Res
, vol.100
, pp. 158-173
-
-
Aird, W.C.1
-
24
-
-
4143101842
-
Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: Roles of LBP and sCD14 in mediating LPS responses
-
Dunzendorfer, S., Lee, H.K., Soldau, K., and Tobias, P.S. 2004. Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses. FASEB J. 18:1117-1119.
-
(2004)
FASEB J
, vol.18
, pp. 1117-1119
-
-
Dunzendorfer, S.1
Lee, H.K.2
Soldau, K.3
Tobias, P.S.4
-
25
-
-
0345798148
-
TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase
-
Fan, J., Frey, R.S., and Malik, A.B. 2003. TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase. J. Clin. Invest. 112:1234-1243.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1234-1243
-
-
Fan, J.1
Frey, R.S.2
Malik, A.B.3
-
26
-
-
0043267638
-
Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells
-
Li, X., et al. 2003. Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells. Infect. Immun. 71:4414-4420.
-
(2003)
Infect. Immun
, vol.71
, pp. 4414-4420
-
-
Li, X.1
-
27
-
-
33745712626
-
GPI-linked endothelial CD14 contributes to the detection of LPS
-
Lloyd, K.L., and Kubes, P. 2006. GPI-linked endothelial CD14 contributes to the detection of LPS. Am. J. Physiol. Heart Circ. Physiol. 291:H473-H481.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol
, vol.291
-
-
Lloyd, K.L.1
Kubes, P.2
-
28
-
-
0034646695
-
Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells
-
Faure, E., et al. 2000. Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells. J. Biol. Chem. 275:11058-11063.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 11058-11063
-
-
Faure, E.1
-
29
-
-
0033583034
-
Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
-
Zhang, F.X., et al. 1999. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J. Biol. Chem. 274:7611-7614.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 7611-7614
-
-
Zhang, F.X.1
-
30
-
-
33846915924
-
Contribution of Toll-like receptors to the innate immune response to Gram-negative and Gram-positive bacteria
-
Elson, G., Dunn-Siegrist, I., Daubeuf, B., and Pugin, J. 2007. Contribution of Toll-like receptors to the innate immune response to Gram-negative and Gram-positive bacteria. Blood. 109:1574-1583.
-
(2007)
Blood
, vol.109
, pp. 1574-1583
-
-
Elson, G.1
Dunn-Siegrist, I.2
Daubeuf, B.3
Pugin, J.4
-
31
-
-
1542373649
-
Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP
-
Andreakos, E., et al. 2004. Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. Blood. 103:2229-2237.
-
(2004)
Blood
, vol.103
, pp. 2229-2237
-
-
Andreakos, E.1
-
32
-
-
0029067723
-
Expression of vascular cell adhesion molecule-1 (VCAM-1) by human brain microvessel endothelial cells in primary culture
-
Wong, D., and Dorovini-Zis, K. 1995. Expression of vascular cell adhesion molecule-1 (VCAM-1) by human brain microvessel endothelial cells in primary culture. Microvasc. Res. 49:325-339.
-
(1995)
Microvasc. Res
, vol.49
, pp. 325-339
-
-
Wong, D.1
Dorovini-Zis, K.2
-
33
-
-
0034102453
-
Expression of the beta-chemokines RANTES and MIP-1 beta by human brain microvessel endothelial cells in primary culture
-
Shukaliak, J.A., and Dorovini-Zis, K. 2000. Expression of the beta-chemokines RANTES and MIP-1 beta by human brain microvessel endothelial cells in primary culture. J. Neuropathol. Exp. Neurol. 59:339-352.
-
(2000)
J. Neuropathol. Exp. Neurol
, vol.59
, pp. 339-352
-
-
Shukaliak, J.A.1
Dorovini-Zis, K.2
-
34
-
-
9644308097
-
Novel chemokine responsiveness and mobilization of neutrophils during sepsis
-
Speyer, C.L., et al. 2004. Novel chemokine responsiveness and mobilization of neutrophils during sepsis. Am. J. Pathol. 165:2187-2196.
-
(2004)
Am. J. Pathol
, vol.165
, pp. 2187-2196
-
-
Speyer, C.L.1
-
35
-
-
0036342372
-
Role of the neutrophil in septic shock and the adult respiratory distress syndrome
-
Aldridge, A.J. 2002. Role of the neutrophil in septic shock and the adult respiratory distress syndrome. Eur. J. Surg. 168:204-214.
-
(2002)
Eur. J. Surg
, vol.168
, pp. 204-214
-
-
Aldridge, A.J.1
-
36
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann, V., et al. 2004. Neutrophil extracellular traps kill bacteria. Science. 303:1532-1535.
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
-
37
-
-
34447525439
-
Beneficial suicide: Why neutrophils die to make NETs
-
Brinkmann, V., and Zychlinsky, A. 2007. Beneficial suicide: why neutrophils die to make NETs. Nat. Rev. Microbiol. 5:577-582.
-
(2007)
Nat. Rev. Microbiol
, vol.5
, pp. 577-582
-
-
Brinkmann, V.1
Zychlinsky, A.2
-
38
-
-
34147188469
-
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
-
Clark, S.R., et al. 2007. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat. Med. 13:463-469.
-
(2007)
Nat. Med
, vol.13
, pp. 463-469
-
-
Clark, S.R.1
-
39
-
-
45149121950
-
Divergent roles of endothelial NF-kappaB in multiple organ injury and bacterial clearance in mouse models of sepsis
-
Ye, X., Ding, J., Zhou, X., Chen, G., and Liu, S.F. 2008. Divergent roles of endothelial NF-kappaB in multiple organ injury and bacterial clearance in mouse models of sepsis. J. Exp. Med. 205:1303-1315.
-
(2008)
J. Exp. Med
, vol.205
, pp. 1303-1315
-
-
Ye, X.1
Ding, J.2
Zhou, X.3
Chen, G.4
Liu, S.F.5
-
40
-
-
0034623813
-
A role for platelets and endothelial selectins in tumor necrosis factor-alpha-induced leukocyte recruitment in the brain microvasculature
-
Carvalho-Tavares, J., et al. 2000. A role for platelets and endothelial selectins in tumor necrosis factor-alpha-induced leukocyte recruitment in the brain microvasculature. Circ. Res. 87:1141-1148.
-
(2000)
Circ. Res
, vol.87
, pp. 1141-1148
-
-
Carvalho-Tavares, J.1
-
41
-
-
0036635706
-
Inducible nitric oxide synthase (iNOS) in endotoxemia: Chimeric mice reveal different cellular sources in various tissues
-
Hickey, M.J., et al. 2002. Inducible nitric oxide synthase (iNOS) in endotoxemia: chimeric mice reveal different cellular sources in various tissues. FASEB J. 16:1141-1143.
-
(2002)
FASEB J
, vol.16
, pp. 1141-1143
-
-
Hickey, M.J.1
-
42
-
-
0034671632
-
L-selectin facilitates emigration and extravascular locomotion of leukocytes during acute inflammatory responses in vivo
-
Hickey, M.J., et al. 2000. L-selectin facilitates emigration and extravascular locomotion of leukocytes during acute inflammatory responses in vivo. J. Immunol. 165:7164-7170.
-
(2000)
J. Immunol
, vol.165
, pp. 7164-7170
-
-
Hickey, M.J.1
-
43
-
-
0029848827
-
Heterogeneity of expression of E- and P-selectins in vivo
-
Eppihimer, M.J., Wolitzky, B., Anderson, D.C., Labow, M.A., and Granger, D.N. 1996. Heterogeneity of expression of E- and P-selectins in vivo. Circ. Res. 79:560-569.
-
(1996)
Circ. Res
, vol.79
, pp. 560-569
-
-
Eppihimer, M.J.1
Wolitzky, B.2
Anderson, D.C.3
Labow, M.A.4
Granger, D.N.5
-
44
-
-
0033555468
-
Varying roles of E-selectin and P-selectin in different microvascular beds in response to antigen
-
Hickey, M.J., et al. 1999. Varying roles of E-selectin and P-selectin in different microvascular beds in response to antigen. J. Immunol. 162:1137-1143.
-
(1999)
J. Immunol
, vol.162
, pp. 1137-1143
-
-
Hickey, M.J.1
|