-
1
-
-
3142724031
-
Toll-like receptor signalling
-
Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4:499.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499
-
-
Akira, S.1
Takeda, K.2
-
2
-
-
2142762520
-
TLRs: Differential adapter utilization by Toll-like receptors mediates TLR-specific patterns of gene expression
-
Vogel, S. N., K. A. Fitzgerald, and M. J. Fenton. 2003. TLRs: differential adapter utilization by Toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 3:466.
-
(2003)
Mol. Interv.
, vol.3
, pp. 466
-
-
Vogel, S.N.1
Fitzgerald, K.A.2
Fenton, M.J.3
-
3
-
-
0032170215
-
Genetic and physical mapping of the Lps locus: Identification of the Toll-4 receptor as a candidate gene in the critical region
-
Poltorak, A., I. Smirnova, X. He, M.Y. Liu, C. Van Huffel, O. McNally, D. Birdwell, E. Alejos, M. Silva, X. Du, et al. 1998. Genetic and physical mapping of the Lps locus: identification of the Toll-4 receptor as a candidate gene in the critical region. Blood Cells Mol. Dis. 24:340.
-
(1998)
Blood Cells Mol. Dis.
, vol.24
, pp. 340
-
-
Poltorak, A.1
Smirnova, I.2
He, X.3
Liu, M.Y.4
Van Huffel, C.5
McNally, O.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Du, X.10
-
4
-
-
0345561540
-
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
-
Qureshi, S. T., L. Lariviere, G. Leveque, S. Clermont, K. J. Moore, P. Gros, and D. Malo. 1999. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189:615.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 615
-
-
Qureshi, S.T.1
Lariviere, L.2
Leveque, G.3
Clermont, S.4
Moore, K.J.5
Gros, P.6
Malo, D.7
-
5
-
-
0035173628
-
CD11b/CD18 acts in concert with CD14 and Toll-like receptor 4 (TLR4) to elicit full lipopolysaccharide and Taxol-inducible gene expression
-
Perera, P.-Y., T. N. Mayadas, O. Takeuchi, S. Akira, M. Zaks-Zilberman, S. M. Goyert, and S. N. Vogel. 2001. CD11b/CD18 acts in concert with CD14 and Toll-like receptor 4 (TLR4) to elicit full lipopolysaccharide and Taxol-inducible gene expression. J. Immunol. 166:574.
-
(2001)
J. Immunol.
, vol.166
, pp. 574
-
-
Perera, P.-Y.1
Mayadas, T.N.2
Takeuchi, O.3
Akira, S.4
Zaks-Zilberman, M.5
Goyert, S.M.6
Vogel, S.N.7
-
6
-
-
0031616595
-
CD14 dependent and independent signaling pathways in murine macrophages from normal or CD 14 "knockout" (CD14 KO) mice stimulated with LPS or Taxol
-
Vogel, S. N., P.-Y. Perera, G. R. Detore, N. Bhat, J. M. Carboni, A. Haziot, and S. M. Goyert. 1998. CD14 dependent and independent signaling pathways in murine macrophages from normal or CD 14 "knockout" (CD14 KO) mice stimulated with LPS or Taxol. Prog. Clin. Biol. Res. 397:137.
-
(1998)
Prog. Clin. Biol. Res.
, vol.397
, pp. 137
-
-
Vogel, S.N.1
Perera, P.-Y.2
Detore, G.R.3
Bhat, N.4
Carboni, J.M.5
Haziot, A.6
Goyert, S.M.7
-
7
-
-
0030784482
-
Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation
-
Haimovitz-Friedman, A., C. Cordon-Cardo, S. Bayoumy, M. Garzotto, M. McLoughlin, R. Gallily, C. K. Edwards, E. H. Schuchman, Z. Fuks, and R. Kolesnick. 1997. Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J. Exp. Med. 186:1831.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1831
-
-
Haimovitz-Friedman, A.1
Cordon-Cardo, C.2
Bayoumy, S.3
Garzotto, M.4
McLoughlin, M.5
Gallily, R.6
Edwards, C.K.7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
8
-
-
0026652968
-
Bacterial components and the pathophysiology of injury to the blood-brain barrier: Does cell wall add to the effect of endotoxin in Gram-negative meningitis?
-
Burroughs, M., C. Cabellos, S. Prasad, and E. Tuomanen. 1992. Bacterial components and the pathophysiology of injury to the blood-brain barrier: does cell wall add to the effect of endotoxin in Gram-negative meningitis? J. Infect. Dis. 165:S82
-
(1992)
J. Infect. Dis.
, vol.165
-
-
Burroughs, M.1
Cabellos, C.2
Prasad, S.3
Tuomanen, E.4
-
9
-
-
0026507291
-
Haemophilis influenzae lipopolysaccharide disrupts confluent monolayers of bovine brain endothelial cells via serum-dependent cytotoxic pathway
-
Patrick, D., J. Betts, E. A. Frey, R. Prameya, K. Dorouni-Zis, and B. B. Finlay. 1992. Haemophilis influenzae lipopolysaccharide disrupts confluent monolayers of bovine brain endothelial cells via serum-dependent cytotoxic pathway. J. Infect. Dis. 165:865.
-
(1992)
J. Infect. Dis.
, vol.165
, pp. 865
-
-
Patrick, D.1
Betts, J.2
Frey, E.A.3
Prameya, R.4
Dorouni-Zis, K.5
Finlay, B.B.6
-
10
-
-
0031720461
-
Immunocompetence of human microvascular brain endothelial cells: Cytokine regulation of IL-1β, MCP-1, IL-10, sICAM-1 and sVCAM-1
-
Frigerio, S., M. Gelati, E. Ciusani, E. Corsini, A. Dufour, G. Massa, and A. Salmaggi. 1998. Immunocompetence of human microvascular brain endothelial cells: cytokine regulation of IL-1β, MCP-1, IL-10, sICAM-1 and sVCAM-1. J. Neurol. 245:727.
-
(1998)
J. Neurol.
, vol.245
, pp. 727
-
-
Frigerio, S.1
Gelati, M.2
Ciusani, E.3
Corsini, E.4
Dufour, A.5
Massa, G.6
Salmaggi, A.7
-
11
-
-
0031973493
-
Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells
-
Schumann, R. R., C. Belka, D. Reuter, N. Lamping, C. J. Kirschning, J. R. Weber, and D. Pfeil. 1998. Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells. Blood 91:577.
-
(1998)
Blood
, vol.91
, pp. 577
-
-
Schumann, R.R.1
Belka, C.2
Reuter, D.3
Lamping, N.4
Kirschning, C.J.5
Weber, J.R.6
Pfeil, D.7
-
12
-
-
0024586781
-
Bacterial lipopolysaccharide and inflammatory mediators augumant IL-6 secretion by human endothelial cells
-
Jirik, F.R., T. J. Podor, T. Hirano, T., Kishimoto, D. J. Loskutoff, D. A. Carson, and M. Lotz. 1989. Bacterial lipopolysaccharide and inflammatory mediators augumant IL-6 secretion by human endothelial cells. J. Immunol. 142:144.
-
(1989)
J. Immunol.
, vol.142
, pp. 144
-
-
Jirik, F.R.1
Podor, T.J.2
Hirano, T.3
Kishimoto, T.4
Loskutoff, D.J.5
Carson, D.A.6
Lotz, M.7
-
13
-
-
0024523417
-
Interleukin-6 gene expression in human endothelial cells: RNA start sites, multiple IL-6 proteins and inhibition of proliferation
-
May, L. T., G. Torcia, F. Cozzolino, A. Ray, S. B. Tatter, U. Santhanam, P. B. Sehgal, and D. Stern. 1989. Interleukin-6 gene expression in human endothelial cells: RNA start sites, multiple IL-6 proteins and inhibition of proliferation. Biochem. Biophys. Res. Commun. 159:991.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.159
, pp. 991
-
-
May, L.T.1
Torcia, G.2
Cozzolino, F.3
Ray, A.4
Tatter, S.B.5
Santhanam, U.6
Sehgal, P.B.7
Stern, D.8
-
14
-
-
0034069380
-
Endotoxin and mast cell granule proteases synergistically activate human coronary artery endothelial cells to generate interleukin-6 and interleukin-8
-
Jehle, A. B., Y. Li, A. C. Stechschulte, D. J. Stechschlute, and K. N. Dileepan. 2000. Endotoxin and mast cell granule proteases synergistically activate human coronary artery endothelial cells to generate interleukin-6 and interleukin-8. J. Interferon Cytokine Res. 4:361.
-
(2000)
J. Interferon Cytokine Res.
, vol.4
, pp. 361
-
-
Jehle, A.B.1
Li, Y.2
Stechschulte, A.C.3
Stechschlute, D.J.4
Dileepan, K.N.5
-
15
-
-
0027428771
-
Analysis of lipopolysaccharide binding by CD14
-
Kirldand, T. N., F. Finley, D. Leturcq, A. Moriarty, J.-D. Lee, R. J. Ulevitch, and P. S. Tobias. 1993. Analysis of lipopolysaccharide binding by CD14. J. Biol. Chem. 268:24818.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24818
-
-
Kirldand, T.N.1
Finley, F.2
Leturcq, D.3
Moriarty, A.4
Lee, J.-D.5
Ulevitch, R.J.6
Tobias, P.S.7
-
16
-
-
0027955127
-
Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14
-
Hailman, E., H. S. Lichenstein, M. M. Wurfel, D. S. Miller, D. A. Johnson, M. Kelly, L. A. Busse, M. M. Zukowski, and S. D. Wright. 1994. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. J. Exp. Med. 179:269.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 269
-
-
Hailman, E.1
Lichenstein, H.S.2
Wurfel, M.M.3
Miller, D.S.4
Johnson, D.A.5
Kelly, M.6
Busse, L.A.7
Zukowski, M.M.8
Wright, S.D.9
-
17
-
-
0029164795
-
Lipopolysaccharide stimulates the tyrosine phosphorylation of mitogen-activated protein kinases p44, p42, and p41 in vascular endothelial cells in a soluble CD14-dependent manner
-
Arditi, M., J. Zhou, M. Torres, D. L. Durden, M. Stins, and K. S. Kim. 1995. Lipopolysaccharide stimulates the tyrosine phosphorylation of mitogen-activated protein kinases p44, p42, and p41 in vascular endothelial cells in a soluble CD14-dependent manner. J. Immunol. 155:3994.
-
(1995)
J. Immunol.
, vol.155
, pp. 3994
-
-
Arditi, M.1
Zhou, J.2
Torres, M.3
Durden, D.L.4
Stins, M.5
Kim, K.S.6
-
18
-
-
0027194212
-
Endotoxin-mediated cell injury and activation: Role of soluble CD14
-
Arditi, M., J. Zhou, R. Dorio, G. W. Rong, S. M. Goyert, and K. S. Kim, 1993. Endotoxin-mediated cell injury and activation: role of soluble CD14. Infect. Immun. 61:3149.
-
(1993)
Infect. Immun.
, vol.61
, pp. 3149
-
-
Arditi, M.1
Zhou, J.2
Dorio, R.3
Rong, G.W.4
Goyert, S.M.5
Kim, K.S.6
-
19
-
-
0027249007
-
Recombinant soluble CD14 mediates the activation of endothelial cells by lipopolysaccharide
-
Haziot, A., G. W. Rong, J. Silver, and S. M. Goyert. 1993. Recombinant soluble CD14 mediates the activation of endothelial cells by lipopolysaccharide. J. Immunol. 151:1500.
-
(1993)
J. Immunol.
, vol.151
, pp. 1500
-
-
Haziot, A.1
Rong, G.W.2
Silver, J.3
Goyert, S.M.4
-
20
-
-
0034680145
-
Toll-like receptors in the induction of the innate immune response
-
Aderem, A., and R. J. Ulevitch. 2000. Toll-like receptors in the induction of the innate immune response. Nature 406:782.
-
(2000)
Nature
, vol.406
, pp. 782
-
-
Aderem, A.1
Ulevitch, R.J.2
-
21
-
-
0034292364
-
Lipopolysaccharide induces physical proximity between CD14 and Toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-κB
-
Jiang, Q., S. Akashi, K. Miyake, and H. R. Petty. 2000. Lipopolysaccharide induces physical proximity between CD14 and Toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-κB. J. Immunol. 165:3541.
-
(2000)
J. Immunol.
, vol.165
, pp. 3541
-
-
Jiang, Q.1
Akashi, S.2
Miyake, K.3
Petty, H.R.4
-
23
-
-
0037096172
-
Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation
-
Triantafilou, M., K. Miyake, D. T. Golenbock, and K. Triantafilou. 2002. Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation. J. Cell Sci. 115:2603.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 2603
-
-
Triantafilou, M.1
Miyake, K.2
Golenbock, D.T.3
Triantafilou, K.4
-
24
-
-
0031984517
-
The many faces of G-protein signaling
-
Hamm, H. E. 1998. The many faces of G-protein signaling. J. Biol. Chem. 273:669.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 669
-
-
Hamm, H.E.1
-
25
-
-
0032504237
-
G protein-coupled receptors. I. Diversity of receptor-ligand interactions
-
Ji, T. H., M. Grossmann, and I. Ji. 1998. G protein-coupled receptors. I. Diversity of receptor-ligand interactions. J. Biol. Chem. 273:17299.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17299
-
-
Ji, T.H.1
Grossmann, M.2
Ji, I.3
-
26
-
-
15444369408
-
G protein-coupled receptors. II. Mechanism of agonist action
-
Gether, U., and B. K. Kobilka. 1998. G protein-coupled receptors. II. Mechanism of agonist action. J. Biol. Chem. 273:17929.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17929
-
-
Gether, U.1
Kobilka, B.K.2
-
27
-
-
0032563291
-
G protein-coupled receptors. III. New roles for kinases and β-arrestins in receptor signaling and desensitization
-
Lefkowitz, R. J. 1998. G protein-coupled receptors. III. New roles for kinases and β-arrestins in receptor signaling and desensitization. J. Biol. Chem. 273:18677.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18677
-
-
Lefkowitz, R.J.1
-
29
-
-
0030047481
-
Signaling from G protein-coupled receptors to c-Jun kinase involves βγ subunits of heterotrimeric G proteins acting on a Ras and Racl-dependent pathway
-
Coso, O. A., H. Teramoto, W. F. Simonds, and J. S. Gutkind. 1996. Signaling from G protein-coupled receptors to c-Jun kinase involves βγ subunits of heterotrimeric G proteins acting on a Ras and Racl-dependent pathway. J. Biol. Chem. 271:3963.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3963
-
-
Coso, O.A.1
Teramoto, H.2
Simonds, W.F.3
Gutkind, J.S.4
-
30
-
-
0030784775
-
Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors
-
Yamauchi, J., M. Nagao, Y. Kaziro, and H. Itoh. 1997. Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors. J. Biol. Chem. 272:27771.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27771
-
-
Yamauchi, J.1
Nagao, M.2
Kaziro, Y.3
Itoh, H.4
-
31
-
-
0032483381
-
αq/11-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase
-
αq/11- induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. J. Biol. Chem. 273:22892.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22892
-
-
Nagao, M.1
Yamauchi, J.2
Kaziro, Y.3
Itoh, H.4
-
33
-
-
0032421572
-
Heterotrimeric G proteins physically associated with the lipopolysaccharide receptor CD14 modulate both in vivo and in vitro responses to lipopolysaccharide
-
Solomon, K. R., E. A. Kurt-Jones, R. A. Saladino, A. M. Stack, I. F. Dunn, M. Ferretti, D. Golenbock, G. R. Fleisher, and R. W. Finberg. 1998. Heterotrimeric G proteins physically associated with the lipopolysaccharide receptor CD14 modulate both in vivo and in vitro responses to lipopolysaccharide. J. Clin. Invest. 102:2019.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 2019
-
-
Solomon, K.R.1
Kurt-Jones, E.A.2
Saladino, R.A.3
Stack, A.M.4
Dunn, I.F.5
Ferretti, M.6
Golenbock, D.7
Fleisher, G.R.8
Finberg, R.W.9
-
34
-
-
0020791359
-
The a protomer of islet-activating protein, pertussis toxin, as an active peptide catalyzing ADP-ribosylation of a membrane protein
-
Katada, T., M. Tamura, and M. Ui. 1983. The A protomer of islet-activating protein, pertussis toxin, as an active peptide catalyzing ADP-ribosylation of a membrane protein. Arch. Biochem. Biophys. 224:290.
-
(1983)
Arch. Biochem. Biophys.
, vol.224
, pp. 290
-
-
Katada, T.1
Tamura, M.2
Ui, M.3
-
35
-
-
15444377632
-
Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins): Mechanism of structural determinants of activity
-
Higashijima, T., S. Uzu, T. Nakajima, and E. M. Ross. 1988. Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins): mechanism of structural determinants of activity. J. Biol. Chem. 265:14176.
-
(1988)
J. Biol. Chem.
, vol.265
, pp. 14176
-
-
Higashijima, T.1
Uzu, S.2
Nakajima, T.3
Ross, E.M.4
-
37
-
-
0022981587
-
Pertussis toxin inhibition of B cell and macrophage responses to bacterial lipopolysaccharide
-
Jakway, J. P., and A. L. DeFranco. 1986. Pertussis toxin inhibition of B cell and macrophage responses to bacterial lipopolysaccharide. Science 234:743.
-
(1986)
Science
, vol.234
, pp. 743
-
-
Jakway, J.P.1
DeFranco, A.L.2
-
39
-
-
0027210436
-
Pertussis toxin-sensitive factor differentially regulates lipopolysaccharide-induced tumor necrosis factor-α and nitric oxide production in mouse peritoneal macrophages
-
Zhang, X., and D. C. Morrison. 1993. Pertussis toxin-sensitive factor differentially regulates lipopolysaccharide-induced tumor necrosis factor-α and nitric oxide production in mouse peritoneal macrophages. J. Immunol. 150:1011.
-
(1993)
J. Immunol.
, vol.150
, pp. 1011
-
-
Zhang, X.1
Morrison, D.C.2
-
40
-
-
0027451272
-
Lipopolysaccharide structure-function relationship in activation vs. reprogramming of mouse peritoneal macrophages
-
Zhang, X., and D. C. Morrison. 1993. Lipopolysaccharide structure-function relationship in activation vs. reprogramming of mouse peritoneal macrophages. J. Leukocyte Biol. 54:444.
-
(1993)
J. Leukocyte Biol.
, vol.54
, pp. 444
-
-
Zhang, X.1
Morrison, D.C.2
-
41
-
-
0014122519
-
Chemical, physical, and biological properties of a lipopolysaccharide from Escherichia coli K-235
-
McIntire, F. C., H. W. Sievert, G. H. Barlow, R. A. Finley, A. Y. Lee. 1967. Chemical, physical, and biological properties of a lipopolysaccharide from Escherichia coli K-235. Biochemistry 6:2363.
-
(1967)
Biochemistry
, vol.6
, pp. 2363
-
-
McIntire, F.C.1
Sievert, H.W.2
Barlow, G.H.3
Finley, R.A.4
Lee, A.Y.5
-
42
-
-
0035879283
-
Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borellia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling
-
Bulut, Y., E. Faure, L. Thomas, O. Equils, and M. Arditi. 2001. Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borellia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. J. Immunol. 167:987.
-
(2001)
J. Immunol.
, vol.167
, pp. 987
-
-
Bulut, Y.1
Faure, E.2
Thomas, L.3
Equils, O.4
Arditi, M.5
-
43
-
-
0033559244
-
An inflammatory polypeptide complex from Staphylococcus epidermidis: Isolation and characterization
-
Mehlin, C., C. M. Headley, and S. J. Klebanoff. 1999. An inflammatory polypeptide complex from Staphylococcus epidermidis: isolation and characterization. J. Exp. Med. 189:907.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 907
-
-
Mehlin, C.1
Headley, C.M.2
Klebanoff, S.J.3
-
44
-
-
0035165287
-
Cutting edge: Functional interactions between Toll-like receptor (TLR) 2 and TLR1 and TLR6 in response to phenolsoluble modulin
-
Hajjar, A. M., D. S. O'Mahony, A. Orlinsky, D. M. Underbill, A. Aderem, S. J. Klebanoff, and C. B. Wilson. 2001. Cutting edge: functional interactions between Toll-like receptor (TLR) 2 and TLR1 and TLR6 in response to phenolsoluble modulin. J. Immunol. 166:15.
-
(2001)
J. Immunol.
, vol.166
, pp. 15
-
-
Hajjar, A.M.1
O'Mahony, D.S.2
Orlinsky, A.3
Underbill, D.M.4
Aderem, A.5
Klebanoff, S.J.6
Wilson, C.B.7
-
45
-
-
0033179698
-
IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice
-
Salkowski, C. A., K. Kopydlowski, J. Blanco, M. J. Cody, R. McNally, and S. N. Vogel. 1999. IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice. J. Immunol. 163:1529.
-
(1999)
J. Immunol.
, vol.163
, pp. 1529
-
-
Salkowski, C.A.1
Kopydlowski, K.2
Blanco, J.3
Cody, M.J.4
McNally, R.5
Vogel, S.N.6
-
46
-
-
0034725584
-
Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells
-
Li, L., S. Cousart, J. Hu, and C. E. McCall. 2000. Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells. J. Biol. Chem. 275:23340.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23340
-
-
Li, L.1
Cousart, S.2
Hu, J.3
McCall, C.E.4
-
47
-
-
0036838930
-
Dysregulation of LPS-induced TLR4-MyD88 complex formation and IRAK-1 activation in endotoxin-tolerant cells
-
Medvedev, A. E., A. Lentschat, L. Wahl, D. T. Golenbock, and S. N. Vogel. 2002. Dysregulation of LPS-induced TLR4-MyD88 complex formation and IRAK-1 activation in endotoxin-tolerant cells. J. Immunol. 169:5209.
-
(2002)
J. Immunol.
, vol.169
, pp. 5209
-
-
Medvedev, A.E.1
Lentschat, A.2
Wahl, L.3
Golenbock, D.T.4
Vogel, S.N.5
-
48
-
-
0043281537
-
Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and Interleukin-1 in a patient with recurrent bacterial infections
-
Medvedev, A. E., A. Lentschat, D. B. Kuhns, J. C. G. Blanco, C. Salkoswski, S. Zhang, M. Arditi, J. I. Gallin, and S. N. Vogel. 2003. Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and Interleukin-1 in a patient with recurrent bacterial infections. J. Exp. Med. 198:521.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 521
-
-
Medvedev, A.E.1
Lentschat, A.2
Kuhns, D.B.3
Blanco, J.C.G.4
Salkoswski, C.5
Zhang, S.6
Arditi, M.7
Gallin, J.I.8
Vogel, S.N.9
-
49
-
-
85039400591
-
-
Patent 5,538,848. Applied Biosystems, Foster City, CA
-
Livak, K., S. Flood, and J. U. S. Marmaro. 2001. Applied Biosystems User Bulletin No. 2. Patent 5,538,848. Applied Biosystems, Foster City, CA.
-
(2001)
Applied Biosystems User Bulletin No. 2
, vol.2
-
-
Livak, K.1
Flood, S.2
Marmaro, J.U.S.3
-
50
-
-
0030997113
-
Structure-function studies of p38 mitogen-activated protein kinase
-
Jiang, Y., Z. Li, E. M. Schwarz, A. Lin, K. Guan, R. J. Ulevitch, and J. Han. 1997. Structure-function studies of p38 mitogen-activated protein kinase. J. Biol. Chem. 272:11096.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11096
-
-
Jiang, Y.1
Li, Z.2
Schwarz, E.M.3
Lin, A.4
Guan, K.5
Ulevitch, R.J.6
Han, J.7
-
51
-
-
0034646695
-
Bacterial lipopolysacharide activates NFκB through Toll-like receptor 4 (TLR4) in cultured human derman endothelial cells
-
Faure, E. O. Equils, P. A. Sieling, L. Thomas, F. X. Zhang, C. J. Kirschning, N. Polentarutti, M. Muzio, and M. Arditi. 2000. Bacterial lipopolysacharide activates NFκB through Toll-like receptor 4 (TLR4) in cultured human derman endothelial cells. J. Biol. Chem. 275:11058.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11058
-
-
Faure, E.1
Equils, O.2
Sieling, P.A.3
Thomas, L.4
Zhang, F.X.5
Kirschning, C.J.6
Polentarutti, N.7
Muzio, M.8
Arditi, M.9
-
52
-
-
0033583034
-
Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human derman endothelial cells and mononuclear phagocytes
-
Zhang, F. X., C. J. Kirschning, R. Mancinelli, X. P. Xu, Y. Jin, E. Faure, A. Mantovani, M. Rothe, M. Muzio, and M. Arditi. 1999. Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human derman endothelial cells and mononuclear phagocytes. J. Biol. Chem. 274:7611.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7611
-
-
Zhang, F.X.1
Kirschning, C.J.2
Mancinelli, R.3
Xu, X.P.4
Jin, Y.5
Faure, E.6
Mantovani, A.7
Rothe, M.8
Muzio, M.9
Arditi, M.10
-
53
-
-
0000007241
-
The role of MAP kinases, phosphatidylinositol 3-kinase, and ceramide in LPS-induced signaling in macrophages
-
H. Brade, S. M. Opal, S. N. Vogel, and D. C. Morrison, eds. Marcel Dekker, New York
-
DeFranco, A. L., A. J. Finn, J. Hambleton, M. T. Crowley, M. L. MacKichan, and S. L Weinstein. 1999. The role of MAP kinases, phosphatidylinositol 3-kinase, and ceramide in LPS-induced signaling in macrophages. In Endotoxin in Health and Disease. H. Brade, S. M. Opal, S. N. Vogel, and D. C. Morrison, eds. Marcel Dekker, New York, p. 473.
-
(1999)
Endotoxin in Health and Disease
, pp. 473
-
-
DeFranco, A.L.1
Finn, A.J.2
Hambleton, J.3
Crowley, M.T.4
MacKichan, M.L.5
Weinstein, S.L.6
-
54
-
-
0029890168
-
Endotoxin signal transduction in macrophages
-
Sweet, M. J., and D. A. Hume. 1996. Endotoxin signal transduction in macrophages. J. Leukocyte Biol. 60:8.
-
(1996)
J. Leukocyte Biol.
, vol.60
, pp. 8
-
-
Sweet, M.J.1
Hume, D.A.2
-
55
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin, M., and Y. Ben-Neriah. 2000. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immun. 18:621.
-
(2000)
Annu. Rev. Immun.
, vol.18
, pp. 621
-
-
Karin, M.1
Ben-Neriah, Y.2
-
56
-
-
0036467447
-
Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway
-
Bulut, Y., E. Faure, L. Thomas, H. Karahashi, K. S. Michelsen, O. Equils, S. G. Morrison, R. P. Morrison, and M. Arditi. 2002. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J. Immunol. 168:1435.
-
(2002)
J. Immunol.
, vol.168
, pp. 1435
-
-
Bulut, Y.1
Faure, E.2
Thomas, L.3
Karahashi, H.4
Michelsen, K.S.5
Equils, O.6
Morrison, S.G.7
Morrison, R.P.8
Arditi, M.9
-
57
-
-
0035115080
-
Signaling by Toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
-
Hirschfeld, M., J. J. Weiss, C. A. Satkowski, M. J. Cody, D. C. Ward, N. Qureshi, S. Michalek, and S. N. Vogel. 2001. Signaling by Toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infect. Immun. 69:1477.
-
(2001)
Infect. Immun.
, vol.69
, pp. 1477
-
-
Hirschfeld, M.1
Weiss, J.J.2
Satkowski, C.A.3
Cody, M.J.4
Ward, D.C.5
Qureshi, N.6
Michalek, S.7
Vogel, S.N.8
-
58
-
-
0036222241
-
TLR4 but not TLR2 stimulates IFN-β-induced STAT1α/β- dependent gene expression in macrophages
-
Toshchakov, V., B. W. Jones, P. Y. Perera, K. Thomas, M. J. Cody, S. Zhang, B. R. Williams, J. Majors, T. A. Hamilton, M. J. Fenton, and S. N. Vogel. 2002. TLR4 but not TLR2 stimulates IFN-β-induced STAT1α/β- dependent gene expression in macrophages. Nat. Immunol. 3:392.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 392
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.Y.3
Thomas, K.4
Cody, M.J.5
Zhang, S.6
Williams, B.R.7
Majors, J.8
Hamilton, T.A.9
Fenton, M.J.10
Vogel, S.N.11
-
59
-
-
0037111523
-
Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages
-
Schilling, D., K. Thomas, K. Nixdorff, S. N. Vogel, and M. J. Fenton. 2002. Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages. J. Immunol. 169:5874.
-
(2002)
J. Immunol.
, vol.169
, pp. 5874
-
-
Schilling, D.1
Thomas, K.2
Nixdorff, K.3
Vogel, S.N.4
Fenton, M.J.5
-
60
-
-
10744223451
-
Purinergic receptor regulation of LPS-induced signaling and pathophysiology
-
Guerra, A. N., P. L. Fisette, Z. A. Pfeiffer, B. H. Quinchia-Rios, U. Prabhu, M. Aga, L. C. Delinger, A. G. Guadarrama, S. Abozeid, J. A. Sommer, et al. 2003. Purinergic receptor regulation of LPS-induced signaling and pathophysiology. J. Endotoxin Res. 9:256.
-
(2003)
J. Endotoxin Res.
, vol.9
, pp. 256
-
-
Guerra, A.N.1
Fisette, P.L.2
Pfeiffer, Z.A.3
Quinchia-Rios, B.H.4
Prabhu, U.5
Aga, M.6
Delinger, L.C.7
Guadarrama, A.G.8
Abozeid, S.9
Sommer, J.A.10
-
61
-
-
0025834532
-
Diversity of G proteins in signal transduction
-
Simon, M. I., M. P. Strathmann, and N. Gautam. 1991. Diversity of G proteins in signal transduction. Science 252:802.
-
(1991)
Science
, vol.252
, pp. 802
-
-
Simon, M.I.1
Strathmann, M.P.2
Gautam, N.3
-
62
-
-
0035316106
-
Signal transduction events in Chinese hamster ovary cells expressing human CD14; effect of endotoxin desensitization
-
2001
-
Ferlito, M., F. Squadrito, P. V. Halushka, and J. A. Cook. 2001. 2001. Signal transduction events in Chinese hamster ovary cells expressing human CD14; effect of endotoxin desensitization. Shock 15:291.
-
(2001)
Shock
, vol.15
, pp. 291
-
-
Ferlito, M.1
Squadrito, F.2
Halushka, P.V.3
Cook, J.A.4
-
64
-
-
0038385023
-
i proteins and src tyrosine kinase in TNFα production induced by lipopolysaccharide, group B streptococci and Staphylococcus aureus
-
i proteins and src tyrosine kinase in TNFα production induced by lipopolysaccharide, group B streptococci and Staphylococcus aureus. Cytokine 22:126.
-
(2003)
Cytokine
, vol.22
, pp. 126
-
-
Fan, H.1
Teti, G.2
Ashton, S.3
Guyton, K.4
Tempel, G.E.5
Halushka, P.V.6
Cook, J.A.7
-
65
-
-
0031616898
-
Endotoxin tolerance alters macrophage membrane regulatory G proteins
-
Makhlouf, M., B. Zingarelli, P. V. Halushka, and J. A. Cook. 1998. Endotoxin tolerance alters macrophage membrane regulatory G proteins. Prog. Clin. Biol. Res. 397:217.
-
(1998)
Prog. Clin. Biol. Res.
, vol.397
, pp. 217
-
-
Makhlouf, M.1
Zingarelli, B.2
Halushka, P.V.3
Cook, J.A.4
-
66
-
-
0033126797
-
Tolerance to LPS decreases macrophage G protein content
-
Fernando, L. P., M. Makhlouf, A. N. Fernando, S. Ashton, P. V. Halushka, and J. A. Cook. 1999. Tolerance to LPS decreases macrophage G protein content. Shock 11:330.
-
(1999)
Shock
, vol.11
, pp. 330
-
-
Fernando, L.P.1
Makhlouf, M.2
Fernando, A.N.3
Ashton, S.4
Halushka, P.V.5
Cook, J.A.6
-
67
-
-
13644270638
-
i protein signaling pathways regulated extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFκB activation
-
i protein signaling pathways regulated extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFκB activation. Shock 22:57.
-
(2004)
Shock
, vol.22
, pp. 57
-
-
Fan, H.1
Peck, O.M.2
Tempel, G.E.3
Halushka, P.V.4
Cook, J.A.5
-
69
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai T., O. Takeuchi, T. Fujita, J. Inoue, P. F. Muhlradt, S. Sato, K. Hoshino, and S. Akira. 2001. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167:5887.
-
(2001)
J. Immunol.
, vol.167
, pp. 5887
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
|