-
1
-
-
0022481133
-
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
-
Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 1986;46:705-16
-
(1986)
Cell
, vol.46
, pp. 705-16
-
-
Sen, R.1
Baltimore, D.2
-
2
-
-
0029976817
-
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
-
Beg AA, Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 1996;274:782-4
-
(1996)
Science
, vol.274
, pp. 782-4
-
-
Beg, A.A.1
Baltimore, D.2
-
3
-
-
3843052483
-
Nuclear factor-kappaB: Its role in health and disease
-
Kumar A, Takada Y, Boriek AM, et al. Nuclear factor-kappaB: its role in health and disease. J Mol Med 2004;82:434-48
-
(2004)
J Mol Med
, vol.82
, pp. 434-48
-
-
Kumar, A.1
Takada, Y.2
Boriek, A.M.3
-
5
-
-
0032556894
-
Crystal structure ofp50/p65 heterodimer of transcription factor NF-kappaB bound to DNA
-
Chen FE, Huang DB, Chen YQ, et al. Crystal structure ofp50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature 1998;391:410-13
-
(1998)
Nature
, vol.391
, pp. 410-13
-
-
Chen, F.E.1
Huang, D.B.2
Chen, Y.Q.3
-
6
-
-
0029924035
-
A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit
-
Lin L, Ghosh S. A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit. Mol Cell Biol 1996;16:2248-54
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2248-54
-
-
Lin, L.1
Ghosh, S.2
-
7
-
-
0031057644
-
Nuclear localization of i kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm
-
Arenzana-Seisdedos F, Turpin P, Rodriguez M, et al. Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm. J Cell Sci 1997;110(Pt 3):369-78
-
(1997)
J Cell Sci
, vol.110
, Issue.PART 3
, pp. 369-78
-
-
Arenzana-Seisdedos, F.1
Turpin, P.2
Rodriguez, M.3
-
8
-
-
0031596724
-
Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: The IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences
-
Sachdev S, Hoffmann A, Hannink M. Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences. Mol Cell Biol 1998;18:2524-34
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2524-34
-
-
Sachdev, S.1
Hoffmann, A.2
Hannink, M.3
-
9
-
-
0033622134
-
Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway
-
Sachdev S, Bagchi S, Zhang DD, et al. Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway. Mol Cell Biol 2000;20:1571-82
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1571-82
-
-
Sachdev, S.1
Bagchi, S.2
Zhang, D.D.3
-
10
-
-
0035976962
-
IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells
-
Malek S, Chen Y, Huxford T, et al. IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells. J Biol Chem 2001;276:45225-35
-
(2001)
J Biol Chem
, vol.276
, pp. 45225-35
-
-
Malek, S.1
Chen, Y.2
Huxford, T.3
-
11
-
-
0032541657
-
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
-
RothwarfDM, Zandi E, Natoli G, et al. IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature 1998;395:297-300
-
(1998)
Nature
, vol.395
, pp. 297-300
-
-
Rothwarf, D.M.1
Zandi, E.2
Natoli, G.3
-
12
-
-
0030613551
-
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
-
Zandi E, RothwarfDM, Delhase M, et al. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 1997;91:243-52
-
(1997)
Cell
, vol.91
, pp. 243-52
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
-
13
-
-
0031906550
-
Signal transduction through NF-kappa B
-
May MJ, Ghosh S. Signal transduction through NF-kappa B. Immunol Today 1998;19:80-8
-
(1998)
Immunol Today
, vol.19
, pp. 80-8
-
-
May, M.J.1
Ghosh, S.2
-
14
-
-
0030271387
-
NF-kappa B: Ten years after
-
Baeuerle PA, Baltimore D. NF-kappa B: ten years after. Cell 1996;87:13-20
-
(1996)
Cell
, vol.87
, pp. 13-20
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
15
-
-
29744443925
-
Transcription factor NF-kappaB: A sensor for smoke and stress signals
-
Ahn KS, Aggarwal BB. Transcription factor NF-kappaB: a sensor for smoke and stress signals. Ann NY Acad Sci 2005;1056:218-33
-
(2005)
Ann NY Acad Sci
, vol.1056
, pp. 218-33
-
-
Ahn, K.S.1
Aggarwal, B.B.2
-
16
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa] B activity
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 2000;18:621-63
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-63
-
-
Karin, M.1
Ben-Neriah, Y.2
-
17
-
-
5644235488
-
NF-kappaB: A multifaceted transcription factor regulated at several levels
-
Schmitz ML, Mattioli I, Buss H, et al. NF-kappaB: a multifaceted transcription factor regulated at several levels. Chem Bio Chem 2004;5:1348-58
-
(2004)
Chem Bio Chem
, vol.5
, pp. 1348-58
-
-
Schmitz, M.L.1
Mattioli, I.2
Buss, H.3
-
18
-
-
0141594607
-
Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation
-
Chen LF, Greene WC. Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation. J Mol Med 2003;81:549-57
-
(2003)
J Mol Med
, vol.81
, pp. 549-57
-
-
Chen, L.F.1
Greene, W.C.2
-
20
-
-
0034745420
-
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
-
Xiao G, Harhaj EW, Sun SC. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol Cell 2001;7:401-9
-
(2001)
Mol Cell
, vol.7
, pp. 401-9
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.C.3
-
21
-
-
0032583947
-
NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176
-
Ling L, Cao Z, Goeddel DV. NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176. Proc Natl Acad Sci USA 1998;95:3792-7
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3792-7
-
-
Ling, L.1
Cao, Z.2
Goeddel, D.V.3
-
22
-
-
33646336615
-
Beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870
-
Liang C, Zhang M, Sun SC. beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870. Cell Signal 2006;18:1309-17
-
(2006)
Cell Signal
, vol.18
, pp. 1309-17
-
-
Liang, C.1
Zhang, M.2
Sun, S.C.3
-
23
-
-
0033523947
-
The generation of nfkb2 p52: Mechanism and efficiency
-
Heusch M, Lin L, Geleziunas R, et al. The generation of nfkb2 p52: mechanism and efficiency. Oncogene 1999;18:6201-8
-
(1999)
Oncogene
, vol.18
, pp. 6201-8
-
-
Heusch, M.1
Lin, L.2
Geleziunas, R.3
-
24
-
-
0032573165
-
Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms
-
Li N, Karin M. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. Proc Natl Acad Sci USA 1998;95:13012-17
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13012-17
-
-
Li, N.1
Karin, M.2
-
25
-
-
0242298578
-
CK2 Is a C-Terminal IkappaB Kinase Responsible for NF-kappaB Activation during the UV Response
-
Kato T Jr, Delhase M, Hoffmann A, et al. CK2 Is a C-Terminal IkappaB Kinase Responsible for NF-kappaB Activation during the UV Response. Mol Cell 2003;12:829-39
-
(2003)
Mol Cell
, vol.12
, pp. 829-39
-
-
Kato Jr., T.1
Delhase, M.2
Hoffmann, A.3
-
26
-
-
36149000984
-
Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha
-
Sethi G, Ahn KS, Chaturvedi MM, et al. Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha. Oncogene 2007;26:7324-32
-
(2007)
Oncogene
, vol.26
, pp. 7324-32
-
-
Sethi, G.1
Ahn, K.S.2
Chaturvedi, M.M.3
-
27
-
-
16044365828
-
Tyrosine phosphorylation of i kappa B-alpha activates NF-kappa B without proteolytic degradation of i kappa B-alpha
-
Imbert V, Rupec RA, Livolsi A, et al. Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha. Cell 1996;86:787-98
-
(1996)
Cell
, vol.86
, pp. 787-98
-
-
Imbert, V.1
Rupec, R.A.2
Livolsi, A.3
-
28
-
-
0037591401
-
Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of i kappa B alpha and serine phosphorylation ofp65: Evidence for the involvement of i kappa B alpha kinase and Syk protein-tyrosine kinase
-
Takada Y, Mukhopadhyay A, Kundu GC, et al. Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation ofp65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase. J Biol Chem 2003;278:24233-41
-
(2003)
J Biol Chem
, vol.278
, pp. 24233-41
-
-
Takada, Y.1
Mukhopadhyay, A.2
Kundu, G.C.3
-
29
-
-
67349245931
-
WIP1 phosphatase is a negative regulator of NF-kappaB signalling
-
Chew J, Biswas S, Shreeram S, et al. WIP1 phosphatase is a negative regulator of NF-kappaB signalling. Nat Cell Biol 2009;11:659-66
-
(2009)
Nat Cell Biol
, vol.11
, pp. 659-66
-
-
Chew, J.1
Biswas, S.2
Shreeram, S.3
-
30
-
-
0037382303
-
The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation
-
Hur GM, Lewis J, Yang Q, et al. The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation. Genes Dev 2003;17:873-82
-
(2003)
Genes Dev
, vol.17
, pp. 873-82
-
-
Hur, G.M.1
Lewis, J.2
Yang, Q.3
-
31
-
-
33646006734
-
Signals from within: The DNA-damage-induced NF-kappaB response
-
Janssens S, Tschopp J. Signals from within: the DNA-damage-induced NF-kappaB response. Cell Death Differ 2006;13:773-84
-
(2006)
Cell Death Differ
, vol.13
, pp. 773-84
-
-
Janssens, S.1
Tschopp, J.2
-
32
-
-
33750435582
-
NF-kappaB and the immune response
-
Hayden MS, West AP, Ghosh S. NF-kappaB and the immune response. Oncogene 2006;25:6758-80
-
(2006)
Oncogene
, vol.25
, pp. 6758-80
-
-
Hayden, M.S.1
West, A.P.2
Ghosh, S.3
-
33
-
-
0032505870
-
NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint
-
Miagkov AV, Kovalenko DV, Brown CE, et al. NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint. Proc Natl Acad Sci USA 1998;95:13859-64
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13859-64
-
-
Miagkov, A.V.1
Kovalenko, D.V.2
Brown, C.E.3
-
34
-
-
0034942860
-
NF-kappa B in rheumatoid arthritis: A pivotal regulator of inflammation, hyperplasia, and tissue destruction
-
Makarov SS. NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction. Arthritis Res 2001;3:200-6
-
(2001)
Arthritis Res
, vol.3
, pp. 200-6
-
-
Makarov, S.S.1
-
35
-
-
15844384253
-
Activation of the transcription factor nuclear factor-kappaB in human inflamed synovial tissue
-
Marok R, Winyard PG, Coumbe A, et al. Activation of the transcription factor nuclear factor-kappaB in human inflamed synovial tissue. Arthritis Rheum 1996;39:583-91
-
(1996)
Arthritis Rheum
, vol.39
, pp. 583-91
-
-
Marok, R.1
Winyard, P.G.2
Coumbe, A.3
-
36
-
-
0026432216
-
Inflammatory bowel disease (1)
-
Podolsky DK. Inflammatory bowel disease (1). N Engl J Med 1991;325:928-37
-
(1991)
N Engl J Med
, vol.325
, pp. 928-37
-
-
Podolsky, D.K.1
-
37
-
-
0026415351
-
Inflammatory bowel disease (2)
-
Podolsky DK. Inflammatory bowel disease (2). N Engl J Med 1991;325:1008-16
-
(1991)
N Engl J Med
, vol.325
, pp. 1008-16
-
-
Podolsky, D.K.1
-
38
-
-
0035139792
-
Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer
-
Yamamoto Y, Gaynor RB. Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J Clin Invest 2001;107:135-42
-
(2001)
J Clin Invest
, vol.107
, pp. 135-42
-
-
Yamamoto, Y.1
Gaynor, R.B.2
-
39
-
-
0035668779
-
A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis
-
Eizirik DL, Mandrup-Poulsen T. A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 2001;44:2115-33
-
(2001)
Diabetologia
, vol.44
, pp. 2115-33
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
40
-
-
0037289746
-
NFkappaB and AP-1 DNA binding activity in patients with multiple sclerosis
-
Flores N, Duran C, Blasco MR, et al. NFkappaB and AP-1 DNA binding activity in patients with multiple sclerosis. J Neuroimmunol 2003;135:141-7
-
(2003)
J Neuroimmunol
, vol.135
, pp. 141-7
-
-
Flores, N.1
Duran, C.2
Blasco, M.R.3
-
41
-
-
33947521041
-
Glucocorticoid receptor, nuclear factor kappaB, activator protein-1 and C-jun N-terminal kinase in systemic lupus erythematosus patients
-
Oikonomidou O, Vlachoyiannopoulos PG, Kominakis A, et al. Glucocorticoid receptor, nuclear factor kappaB, activator protein-1 and C-jun N-terminal kinase in systemic lupus erythematosus patients. Neuroimmunomodulation 2006;13:194-204
-
(2006)
Neuroimmunomodulation
, vol.13
, pp. 194-204
-
-
Oikonomidou, O.1
Vlachoyiannopoulos, P.G.2
Kominakis, A.3
-
42
-
-
20544461306
-
Inverse regulation of the nuclear factor-kappaB binding to the p53 and interleukin-8 kappaB response elements in lesional psoriatic skin
-
Johansen C, Flindt E, Kragballe K, et al. Inverse regulation of the nuclear factor-kappaB binding to the p53 and interleukin-8 kappaB response elements in lesional psoriatic skin. J Invest Dermatol 2005;124:1284-92
-
(2005)
J Invest Dermatol
, vol.124
, pp. 1284-92
-
-
Johansen, C.1
Flindt, E.2
Kragballe, K.3
-
43
-
-
77958038475
-
NF-kappaB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia
-
Breccia M, Alimena G. NF-kappaB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia. Expert Opin Ther Targets 2010;14:1157-76
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 1157-76
-
-
Breccia, M.1
Alimena, G.2
-
44
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006;441:431-6
-
(2006)
Nature
, vol.441
, pp. 431-6
-
-
Karin, M.1
-
45
-
-
0042663849
-
Inhibition of inducible NF-kappaB activity reduces chemoresistance to 5-fluorouracil in human stomach cancer cell line
-
Uetsuka H, Haisa M, Kimura M, et al. Inhibition of inducible NF-kappaB activity reduces chemoresistance to 5-fluorouracil in human stomach cancer cell line. Exp Cell Res 2003;289:27-35
-
(2003)
Exp Cell Res
, vol.289
, pp. 27-35
-
-
Uetsuka, H.1
Haisa, M.2
Kimura, M.3
-
46
-
-
0034722884
-
Bcl-2 family proteins as targets for anticancer drug design
-
Huang Z. Bcl-2 family proteins as targets for anticancer drug design. Oncogene 2000;19:6627-31
-
(2000)
Oncogene
, vol.19
, pp. 6627-31
-
-
Huang, Z.1
-
47
-
-
0037151030
-
Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax
-
Werner AB, de Vries E, Tait SW, et al. Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax. J Biol Chem 2002;277:22781-8
-
(2002)
J Biol Chem
, vol.277
, pp. 22781-8
-
-
Werner, A.B.1
De Vries, E.2
Tait, S.W.3
-
48
-
-
65249086258
-
P65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541
-
Lopez-Guerra M, Roue G, Perez-Galan P, et al. p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541. Clin Cancer Res 2009;15:2767-76
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2767-76
-
-
Lopez-Guerra, M.1
Roue, G.2
Perez-Galan, P.3
-
50
-
-
21544441173
-
NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein
-
Brandt S, Kwok T, Hartig R, et al. NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein. Proc Natl Acad Sci USA 2005;102:9300-5
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9300-5
-
-
Brandt, S.1
Kwok, T.2
Hartig, R.3
-
51
-
-
0034235373
-
H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells
-
Maeda S, Yoshida H, Ogura K, et al. H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells. Gastroenterology 2000;119:97-108
-
(2000)
Gastroenterology
, vol.119
, pp. 97-108
-
-
Maeda, S.1
Yoshida, H.2
Ogura, K.3
-
52
-
-
0036709174
-
Nuclear factor-kappa B and cancer: Its role in prevention and therapy
-
Bharti AC, Aggarwal BB. Nuclear factor-kappa B and cancer: its role in prevention and therapy. Biochem Pharmacol 2002;64:883-8
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 883-8
-
-
Bharti, A.C.1
Aggarwal, B.B.2
-
53
-
-
0032577708
-
Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates
-
Giri DK, Aggarwal BB. Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates. J Biol Chem 1998;273:14008-14
-
(1998)
J Biol Chem
, vol.273
, pp. 14008-14
-
-
Giri, D.K.1
Aggarwal, B.B.2
-
54
-
-
0034827441
-
Antiproliferative effects of IFN-alpha correlate with the downregulation of nuclear factor-kappa B in human Burkitt lymphoma Daudi cells
-
Rath PC, Aggarwal BB. Antiproliferative effects of IFN-alpha correlate with the downregulation of nuclear factor-kappa B in human Burkitt lymphoma Daudi cells. J Interferon Cytokine Res 2001;21:523-8
-
(2001)
J Interferon Cytokine Res
, vol.21
, pp. 523-8
-
-
Rath, P.C.1
Aggarwal, B.B.2
-
55
-
-
0037409887
-
Nuclear transcription factor-kappaB in Hodgkin's disease
-
Younes A, Garg A, Aggarwal BB. Nuclear transcription factor-kappaB in Hodgkin's disease. Leuk Lymphoma 2003;44:929-35
-
(2003)
Leuk Lymphoma
, vol.44
, pp. 929-35
-
-
Younes, A.1
Garg, A.2
Aggarwal, B.B.3
-
56
-
-
0034885358
-
New insights into the role of nuclear factor-kappaB in cell growth regulation
-
Chen F, Castranova V, Shi X. New insights into the role of nuclear factor-kappaB in cell growth regulation. Am J Pathol 2001;159:387-97
-
(2001)
Am J Pathol
, vol.159
, pp. 387-97
-
-
Chen, F.1
Castranova, V.2
Shi, X.3
-
57
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of i (kappa)B kinase-beta
-
Yin MJ, Yamamoto Y, Gaynor RB. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I (kappa)B kinase-beta. Nature 1998;396:77-80
-
(1998)
Nature
, vol.396
, pp. 77-80
-
-
Yin, M.J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
58
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest 2001;107:241-6
-
(2001)
J Clin Invest
, vol.107
, pp. 241-6
-
-
Baldwin, A.S.1
-
59
-
-
33845943499
-
Simvastatin inhibits NF-kappaB signaling in intestinal epithelial cells and ameliorates acute murine colitis
-
Lee JY, Kim JS, Kim JM, et al. Simvastatin inhibits NF-kappaB signaling in intestinal epithelial cells and ameliorates acute murine colitis. Int Immunopharmacol 2007;7:241-8
-
(2007)
Int Immunopharmacol
, vol.7
, pp. 241-8
-
-
Lee, J.Y.1
Kim, J.S.2
Kim, J.M.3
-
60
-
-
33645825623
-
Raloxifene-induced myeloma cell apoptosis: A study of nuclear factor-kappaB inhibition and gene expression signature
-
Olivier S, Close P, Castermans E, et al. Raloxifene-induced myeloma cell apoptosis: a study of nuclear factor-kappaB inhibition and gene expression signature. Mol Pharmacol 2006;69:1615-23
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1615-23
-
-
Olivier, S.1
Close, P.2
Castermans, E.3
-
61
-
-
17644379385
-
Pharmacology, pharmacokinetics, and practical applications of bortezomib
-
Schwartz R, Davidson T. Pharmacology, pharmacokinetics, and practical applications of bortezomib. Oncology (Williston Park) 2004;18:14-21
-
(2004)
Oncology (Williston Park)
, vol.18
, pp. 14-21
-
-
Schwartz, R.1
Davidson, T.2
-
62
-
-
0032032469
-
Sulfasalazine: A potent and specific inhibitor of nuclear factor kappa B
-
Wahl C, Liptay S, Adler G, et al. Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J Clin Invest 1998;101:1163-74
-
(1998)
J Clin Invest
, vol.101
, pp. 1163-74
-
-
Wahl, C.1
Liptay, S.2
Adler, G.3
-
63
-
-
0034322370
-
Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta
-
University ofSouthampton. GB2421947; 2006
-
Weber CK, Liptay S, Wirth T, et al. Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta. Gastroenterology 2000;119:1209-18 University ofSouthampton. GB2421947; 2006
-
(2000)
Gastroenterology
, vol.119
, pp. 1209-18
-
-
Weber, C.K.1
Liptay, S.2
Wirth, T.3
-
64
-
-
81855162867
-
-
Je Il Pharmaceutical Co WO2007102679
-
Je Il Pharmaceutical Co. WO2007102679; 2007
-
(2007)
-
-
-
65
-
-
25644438318
-
Antiinflammatory and immunomodulating properties of fungal metabolites
-
Lull C, Wichers HJ, Savelkoul HF. Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm 2005;2005:63-80
-
(2005)
Mediators Inflamm
, vol.2005
, pp. 63-80
-
-
Lull, C.1
Wichers, H.J.2
Savelkoul, H.F.3
-
66
-
-
33744543916
-
Beta-(1->3)-D-glucan modulates DNA binding of nuclear factors kappaB, at and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio
-
Luhm J, Langenkamp U, Hensel J, et al. Beta-(1->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. BMC Immunol 2006;7:5
-
(2006)
BMC Immunol
, vol.7
, pp. 5
-
-
Luhm, J.1
Langenkamp, U.2
Hensel, J.3
-
67
-
-
81855188285
-
-
Hypha Holdings Pte Ltd. WO2009017463
-
Hypha Holdings Pte Ltd. WO2009017463; 2009
-
(2009)
-
-
-
68
-
-
81855188286
-
-
Henrich et al WO2010033958;
-
Henrich et al. WO2010033958; 2010
-
(2010)
-
-
-
69
-
-
0030294698
-
PR-39, a proline-rich peptide antibiotic from pig, and FALL-39, a tentative human counterpart
-
Agerberth B, Gunne H, Odeberg J, et al. PR-39, a proline-rich peptide antibiotic from pig, and FALL-39, a tentative human counterpart. Vet Immunol Immunopathol 1996;54:127-31
-
(1996)
Vet Immunol Immunopathol
, vol.54
, pp. 127-31
-
-
Agerberth, B.1
Gunne, H.2
Odeberg, J.3
-
70
-
-
0033970878
-
PR39, a peptide regulator of angiogenesis
-
Li J, Post M, Volk R, et al. PR39, a peptide regulator of angiogenesis. Nat Med 2000;6:49-55
-
(2000)
Nat Med
, vol.6
, pp. 49-55
-
-
Li, J.1
Post, M.2
Volk, R.3
-
71
-
-
0033847049
-
Inhibition of ubiquitin-proteasome pathway-mediated i kappa B alpha degradation by a naturally occurring antibacterial peptide
-
Gao Y, Lecker S, Post MJ, et al. Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide. J Clin Invest 2000;106:439-48
-
(2000)
J Clin Invest
, vol.106
, pp. 439-48
-
-
Gao, Y.1
Lecker, S.2
Post, M.J.3
-
73
-
-
81855214690
-
-
Sc Ag US20060069102
-
Sc Ag. US20060069102; 2006
-
(2006)
-
-
-
74
-
-
81855162872
-
-
Sc Ag WO2007104558
-
Sc Ag. WO2007104558; 2007
-
(2007)
-
-
-
75
-
-
81855165335
-
-
University of Ulsan Foundation for Industry Cooperation. WO2008069632
-
University of Ulsan Foundation for Industry Cooperation. WO2008069632; 2008
-
(2008)
-
-
-
76
-
-
81855214692
-
-
Misigan State University WO2007133790
-
Misigan State University. WO2007133790; 2007
-
(2007)
-
-
-
77
-
-
0036978903
-
Synthesis and structure-activity relationship of dehydroxymethylepoxyquinomicin analogues as inhibitors of NF-kappaB functions
-
Chaicharoenpong C, Kato K, Umezawa K. Synthesis and structure-activity relationship of dehydroxymethylepoxyquinomicin analogues as inhibitors of NF-kappaB functions. Bioorg Med Chem 2002;10:3933-9
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 3933-9
-
-
Chaicharoenpong, C.1
Kato, K.2
Umezawa, K.3
-
78
-
-
0037025347
-
Inhibition of tumor necrosis factor-alpha -induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin
-
Ariga A, Namekawa J, Matsumoto N, et al. Inhibition of tumor necrosis factor-alpha -induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin. J Biol Chem 2002;277:24625-30
-
(2002)
J Biol Chem
, vol.277
, pp. 24625-30
-
-
Ariga, A.1
Namekawa, J.2
Matsumoto, N.3
-
79
-
-
81855162873
-
-
Profectus Biosciences WO2010148042
-
Profectus Biosciences. WO2010148042; 2010
-
(2010)
-
-
-
80
-
-
81855165338
-
-
Profectus Biosciences WO2010127058
-
Profectus Biosciences. WO2010127058; 2010
-
(2010)
-
-
-
81
-
-
81855214691
-
-
Profectus Biosciences WO2010111460
-
Profectus Biosciences. WO2010111460; 2010
-
(2010)
-
-
-
82
-
-
7444239683
-
Inhibitory mechanism of chroman compound on LPS-induced nitric oxide production and nuclear factor-kappaB activation
-
Kim BH, Reddy AM, Lee KH, et al. Inhibitory mechanism of chroman compound on LPS-induced nitric oxide production and nuclear factor-kappaB activation. Biochem Biophys Res Commun 2004;325:223-8
-
(2004)
Biochem Biophys Res Commun
, vol.325
, pp. 223-8
-
-
Kim, B.H.1
Reddy, A.M.2
Lee, K.H.3
-
83
-
-
81855162869
-
-
Chungbuk National University, Industry-Academy Cooperation Foundation KR784850
-
Chungbuk National University, Industry-Academy Cooperation Foundation. KR784850; 2007
-
(2007)
-
-
-
84
-
-
81855165334
-
-
Chungbuk National University Industry-Academy Cooperation Foundation KR2010044509
-
Chungbuk National University, Industry-Academy Cooperation Foundation. KR2010044509; 2010
-
(2010)
-
-
-
85
-
-
81855188287
-
-
Rho et al. WO2010041827; 2010
-
Rho et al. WO2010041827; 2010
-
-
-
-
89
-
-
0030976857
-
Characterization of mechanisms of interleukin-6 gene repression by estrogen receptor
-
Kurebayashi S, Miyashita Y, Hirose T, et al. Characterization of mechanisms of interleukin-6 gene repression by estrogen receptor. J Steroid Biochem Mol Biol 1997;60:11-17
-
(1997)
J Steroid Biochem Mol Biol
, vol.60
, pp. 11-17
-
-
Kurebayashi, S.1
Miyashita, Y.2
Hirose, T.3
-
90
-
-
0020562898
-
Estrogen-induced creatine kinase in the reproductive system of the immature female rat
-
Malnick SD, Shaer A, Soreq H, et al. Estrogen-induced creatine kinase in the reproductive system of the immature female rat. Endocrinology 1983;113:1907-9
-
(1983)
Endocrinology
, vol.113
, pp. 1907-9
-
-
Malnick, S.D.1
Shaer, A.2
Soreq, H.3
-
91
-
-
0032547326
-
Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group
-
Hulley S, Grady D, Bush T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. J Am Med Assoc 1998;280:605-13
-
(1998)
J Am Med Assoc
, vol.280
, pp. 605-13
-
-
Hulley, S.1
Grady, D.2
Bush, T.3
-
92
-
-
81855188284
-
-
WO2006050006
-
Wyeth. WO2006050006; 2006
-
(2006)
Wyeth
-
-
-
93
-
-
0032931517
-
The p53 pathway
-
Prives C, Hall PA. The p53 pathway. J Pathol 1999;187:112-26
-
(1999)
J Pathol
, vol.187
, pp. 112-26
-
-
Prives, C.1
Hall, P.A.2
-
94
-
-
51849169337
-
IL-8 and p53 are inversely regulated through JNK, p38 and NF-kappaB p65 in HepG2 cells during an inflammatory response
-
Rasmussen MK, Iversen L, Johansen C, et al. IL-8 and p53 are inversely regulated through JNK, p38 and NF-kappaB p65 in HepG2 cells during an inflammatory response. Inflamm Res 2008;57:329-39
-
(2008)
Inflamm Res
, vol.57
, pp. 329-39
-
-
Rasmussen, M.K.1
Iversen, L.2
Johansen, C.3
-
95
-
-
81855162868
-
-
Cleveland Clinic Foundation WO2006012419
-
Cleveland Clinic Foundation. WO2006012419; 2006
-
(2006)
-
-
-
96
-
-
81855162870
-
-
Sudarsanam et al US20090306073
-
Sudarsanam et al. US20090306073; 2009
-
(2009)
-
-
-
97
-
-
33745489486
-
Patented inhibitors (2002 -2005) of the transcription factor NF-kappaB
-
Merfort I. Patented inhibitors (2002 - 2005) of the transcription factor NF-kappaB. Expert Opin Ther Patent 2006;16:797-810
-
(2006)
Expert Opin Ther Patent
, vol.16
, pp. 797-810
-
-
Merfort, I.1
-
98
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G, Whyte DB, Martinez R et al. The protein kinase complement of the human genome. Science 2002;298:1912-34
-
(2002)
Science
, vol.298
, pp. 1912-34
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
-
99
-
-
0033026444
-
Strategies toward the design of novel and selective protein tyrosine kinase inhibitors
-
Traxler P, Furet P. Strategies toward the design of novel and selective protein tyrosine kinase inhibitors. Pharmacol Ther 1999;82:195-206
-
(1999)
Pharmacol Ther
, vol.82
, pp. 195-206
-
-
Traxler, P.1
Furet, P.2
|