IL-8 and p53 are inversely regulated through JNK, p38 and NF-κB p65 in HepG2 cells during an inflammatory response

Inflammation Research

Volumn 57, Issue 7, 2008, Pages 329-339

  Rasmussen, M K ^a   Iversen, L ^a   Johansen, C ^a   Finnemann, J ^b   Olsen, L S ^b   Kragballe, K ^a   Gesser, Borbala ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b LEO PHARMA A S   (Denmark)

Author keywords

IL 8; JNK; NF B p65; P38 MAPK; P53

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P50; PROTEIN P53; SC 514; SMALL INTERFERING RNA; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; WESTERN BLOTTING;

CELL LINE; CELL NUCLEUS; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERLEUKIN-8; MODELS, BIOLOGICAL; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, SMALL INTERFERING; TIME FACTORS; TRANSCRIPTION FACTOR RELA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 51849169337     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-007-7220-1     Document Type: Article

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