-
1
-
-
74949136580
-
Immunotherapy of malignant disease with tumor antigen-specific monoclonal antibodies
-
PMID:20028761; DOI:10.1158/1078-0432.CCR-09-2345
-
Campoli M, Ferris R, Ferrone S, Wang X. Immunotherapy of malignant disease with tumor antigen-specific monoclonal antibodies. Clin Cancer Res 2010; 16:11-20; PMID:20028761; DOI:10.1158/1078-0432.CCR-09-2345.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 11-20
-
-
Campoli, M.1
Ferris, R.2
Ferrone, S.3
Wang, X.4
-
2
-
-
77951529848
-
Therapeutic antibodies for autoimmunity and inflammation
-
PMID:20414204; DOI:10.1038/nri2761
-
Chan AC, Carter PJ. Therapeutic antibodies for autoimmunity and inflammation. Nat Rev Immunol 2010; 10:301-16; PMID:20414204; DOI:10.1038/nri2761.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 301-316
-
-
Chan, A.C.1
Carter, P.J.2
-
3
-
-
77951614830
-
Monoclonal antibodies: Versatile platforms for cancer immunotherapy
-
PMID:20414205; DOI:10.1038/nri2744
-
Weiner LM, Surana R, Wang S. Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat Rev Immunol 2010; 10:317-27; PMID:20414205; DOI:10.1038/nri2744.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 317-327
-
-
Weiner, L.M.1
Surana, R.2
Wang, S.3
-
4
-
-
67649851892
-
mAbs: A business perspective
-
PMID:20061824; DOI:10.4161/mabs.1.2.7736
-
Scolnik PA. mAbs: a business perspective. MAbs 2009; 1:179-84; PMID:20061824; DOI:10.4161/mabs.1.2.7736.
-
(2009)
MAbs
, vol.1
, pp. 179-184
-
-
Scolnik, P.A.1
-
5
-
-
78651387929
-
Antibody-based therapeutics to watch in 2011
-
PMID:21051951; DOI:10.4161/mabs.3.1.13895
-
Reichert JM. Antibody-based therapeutics to watch in 2011. MAbs 2011; 3:76-99; PMID:21051951; DOI:10.4161/mabs.3.1.13895.
-
(2011)
MAbs
, vol.3
, pp. 76-99
-
-
Reichert, J.M.1
-
6
-
-
59849122181
-
The cancer vaccine roller coaster
-
PMID:19204689; DOI:10.1038/nbt0209-129
-
Goldman B, DeFrancesco L. The cancer vaccine roller coaster. Nat Biotechnol 2009; 27:129-39; PMID:19204689; DOI:10.1038/nbt0209-129.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 129-139
-
-
Goldman, B.1
DeFrancesco, L.2
-
7
-
-
79955814192
-
Sipuleucel-T: Prototype for development of anti-tumor vaccines
-
PMID:21243538; DOI:10.1007/s11912-011-0152-5
-
Carballido E, Fishman M. Sipuleucel-T: Prototype for development of anti-tumor vaccines. Curr Oncol Rep 2011; 13:112-9; PMID:21243538; DOI:10.1007/s11912-011-0152-5.
-
(2011)
Curr Oncol Rep
, vol.13
, pp. 112-119
-
-
Carballido, E.1
Fishman, M.2
-
8
-
-
78650574270
-
Therapeutic cancer vaccines: Are we there yet?
-
PMID:21198663; DOI:10.1111/j.1600-065X.2010.00979.x
-
Klebanoff CA, Acquavella N, Yu Z, Restifo NP. Therapeutic cancer vaccines: are we there yet? Immunol Rev 2011; 239:27-44; PMID:21198663; DOI:10.1111/j.1600-065X.2010.00979.x.
-
(2011)
Immunol Rev
, vol.239
, pp. 27-44
-
-
Klebanoff, C.A.1
Acquavella, N.2
Yu, Z.3
Restifo, N.P.4
-
9
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
PMID:21376230; DOI:10.1016/j.cell.2011.02.013
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-74; PMID:21376230; DOI:10.1016/j.cell.2011.02.013.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
10
-
-
77951586447
-
Strategies and challenges for the next generation of therapeutic antibodies
-
PMID:20414207; DOI:10.1038/nri2747
-
Beck A, Wurch T, Bailly C, Corvaia N. Strategies and challenges for the next generation of therapeutic antibodies. Nat Rev Immunol 2010; 10:345-52; PMID:20414207; DOI:10.1038/nri2747.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 345-352
-
-
Beck, A.1
Wurch, T.2
Bailly, C.3
Corvaia, N.4
-
11
-
-
77953373333
-
Anti-idiotypic antibodies and "tumor-only" antigens: An update
-
DOI:10.2174/1874226200902010001
-
Lopez-Requena A, Burrone OR. Anti-idiotypic antibodies and "tumor-only" antigens: an update. Open Immunol J 2009; 2:1-8; DOI:10.2174/1874226200902010001.
-
(2009)
Open Immunol J
, vol.2
, pp. 1-8
-
-
Lopez-Requena, A.1
Burrone, O.R.2
-
12
-
-
77952019858
-
Construction of a recombinant non-mitogenic anti-human CD3 antibody
-
(Larchmt) PMID:20443703; DOI:10.1089/hyb.2009.0042
-
Hinojosa LE, Hernandez T, de Acosta CM, Montero E, Perez R, Lopez-Requena A. Construction of a recombinant non-mitogenic anti-human CD3 antibody. Hybridoma (Larchmt) 2010; 29:115-24; PMID:20443703; DOI:10.1089/hyb.2009.0042.
-
(2010)
Hybridoma
, vol.29
, pp. 115-124
-
-
Hinojosa, L.E.1
Hernandez, T.2
De Acosta, C.M.3
Montero, E.4
Perez, R.5
Lopez-Requena, A.6
-
13
-
-
50249165877
-
Towards the definition of a chimpanzee and human conserved CD6 domain 1 epitope recognized by T1 monoclonal antibody
-
(Larchmt) PMID:18707547; DOI:10.1089/hyb.2008.0007
-
Alonso R, Huerta V, de Leon J, Piedra P, Puchades Y, Guirola O, et al. Towards the definition of a chimpanzee and human conserved CD6 domain 1 epitope recognized by T1 monoclonal antibody. Hybridoma (Larchmt) 2008; 27:291-301; PMID:18707547; DOI:10.1089/hyb.2008.0007.
-
(2008)
Hybridoma
, vol.27
, pp. 291-301
-
-
Alonso, R.1
Huerta, V.2
De Leon, J.3
Piedra, P.4
Puchades, Y.5
Guirola, O.6
-
14
-
-
78650730811
-
NGcGM3 ganglioside: A privileged target for cancer vaccines
-
PMID:21048926; DOI:10.1155/2010/814397
-
Fernandez LE, Gabri MR, Guthmann MD, Gomez RE, Gold S, Fainboim L, et al. NGcGM3 ganglioside: a privileged target for cancer vaccines. Clin Dev Immunol 2010; 2010:814397. PMID:21048926; DOI:10.1155/2010/814397.
-
(2010)
Clin Dev Immunol
, vol.2010
, pp. 814397
-
-
Fernandez, L.E.1
Gabri, M.R.2
Guthmann, M.D.3
Gomez, R.E.4
Gold, S.5
Fainboim, L.6
-
15
-
-
41149097757
-
Engineering therapeutic monoclonal antibodies
-
PMID:18363992; DOI:10.1111/j.1600-065X.2008.00601.x
-
Liu XY, Pop LM, Vitetta ES. Engineering therapeutic monoclonal antibodies. Immunol Rev 2008; 222:9-27; PMID:18363992; DOI:10.1111/j.1600-065X. 2008.00601.x.
-
(2008)
Immunol Rev
, vol.222
, pp. 9-27
-
-
Liu, X.Y.1
Pop, L.M.2
Vitetta, E.S.3
-
16
-
-
7244248664
-
From the bench to the bedside: Ways to improve rituximab efficacy
-
PMID:15226177; DOI:10.1182/blood-2004-03-1110
-
Cartron G, Watier H, Golay J, Solal-Celigny P. From the bench to the bedside: ways to improve rituximab efficacy. Blood 2004; 104:2635-42; PMID:15226177; DOI:10.1182/blood-2004-03-1110.
-
(2004)
Blood
, vol.104
, pp. 2635-2642
-
-
Cartron, G.1
Watier, H.2
Golay, J.3
Solal-Celigny, P.4
-
17
-
-
77950332103
-
Rituximab: Mechanism of action
-
PMID:20350658; DOI:10.1053/j.seminhematol.2010.01.011
-
Weiner GJ. Rituximab: mechanism of action. Semin Hematol 2010; 47:115-23; PMID:20350658; DOI:10.1053/j.seminhematol.2010.01.011.
-
(2010)
Semin Hematol
, vol.47
, pp. 115-123
-
-
Weiner, G.J.1
-
18
-
-
57649149333
-
Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009
-
PMID:18846107; DOI:10.1038/cdd.2008.150
-
Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH, et al. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 2009; 16:3-11; PMID:18846107; DOI:10.1038/cdd.2008.150.
-
(2009)
Cell Death Differ
, vol.16
, pp. 3-11
-
-
Kroemer, G.1
Galluzzi, L.2
Vandenabeele, P.3
Abrams, J.4
Alnemri, E.S.5
Baehrecke, E.H.6
-
19
-
-
38449118285
-
IgE-antibody-dependent immunotherapy of solid tumors: Cytotoxic and phagocytic mechanisms of eradication of ovarian cancer cells
-
PMID:17709497
-
Karagiannis SN, Bracher MG, Hunt J, McCloskey N, Beavil RL, Beavil AJ, et al. IgE-antibody-dependent immunotherapy of solid tumors: cytotoxic and phagocytic mechanisms of eradication of ovarian cancer cells. J Immunol 2007; 179:2832-43; PMID:17709497.
-
(2007)
J Immunol
, vol.179
, pp. 2832-2843
-
-
Karagiannis, S.N.1
Bracher, M.G.2
Hunt, J.3
McCloskey, N.4
Beavil, R.L.5
Beavil, A.J.6
-
20
-
-
36349021388
-
Role of IgE receptors in IgE antibody-dependent cytotoxicity and phagocytosis of ovarian tumor cells by human monocytic cells
-
PMID:17657488; DOI:10.1007/s00262-007-0371-7
-
Karagiannis SN, Bracher MG, Beavil RL, Beavil AJ, Hunt J, McCloskey N, et al. Role of IgE receptors in IgE antibody-dependent cytotoxicity and phagocytosis of ovarian tumor cells by human monocytic cells. Cancer Immunol Immunother 2008; 57:247-63; PMID:17657488; DOI:10.1007/s00262-007-0371-7.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 247-263
-
-
Karagiannis, S.N.1
Bracher, M.G.2
Beavil, R.L.3
Beavil, A.J.4
Hunt, J.5
McCloskey, N.6
-
21
-
-
63949083569
-
Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells
-
PMID:18941743; DOI:10.1007/s00262-008-0607-1
-
Karagiannis P, Singer J, Hunt J, Gan SK, Rudman SM, Mechtcheriakova D, et al. Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells. Cancer Immunol Immunother 2009; 58:915-30; PMID:18941743; DOI:10.1007/s00262-008-0607-1.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 915-930
-
-
Karagiannis, P.1
Singer, J.2
Hunt, J.3
Gan, S.K.4
Rudman, S.M.5
Mechtcheriakova, D.6
-
22
-
-
51349168516
-
Allergo Oncology: The role of IgE-mediated allergy in cancer
-
PMID:18671772; DOI:10.1111/j.1398-9995.2008.01768.x
-
Jensen-Jarolim E, Achatz G, Turner MC, Karagiannis S, Legrand F, Capron M, et al. Allergo Oncology: the role of IgE-mediated allergy in cancer. Allergy 2008; 63:1255-66; PMID:18671772; DOI:10.1111/j.1398-9995.2008.01768.x.
-
(2008)
Allergy
, vol.63
, pp. 1255-1266
-
-
Jensen-Jarolim, E.1
Achatz, G.2
Turner, M.C.3
Karagiannis, S.4
Legrand, F.5
Capron, M.6
-
23
-
-
3543092021
-
Pathways of apoptotic and non-apoptotic death in tumour cells
-
PMID:15286739; DOI:10.1038/nrc1412
-
Okada H, Mak TW. Pathways of apoptotic and non-apoptotic death in tumour cells. Nat Rev Cancer 2004; 4:592-603; PMID:15286739; DOI:10.1038/nrc1412.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 592-603
-
-
Okada, H.1
Mak, T.W.2
-
24
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
PMID:11483992; DOI:10.1038/35085008
-
Leist M, Jaattela M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001; 2:589-98; PMID:11483992; DOI:10.1038/35085008.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
25
-
-
79952122944
-
Cell death assays for drug discovery
-
PMID:21358741; DOI:10.1038/nrd3373
-
Kepp O, Galluzzi L, Lipinski M, Yuan J, Kroemer G. Cell death assays for drug discovery. Nat Rev Drug Discov 2011; 10:221-37; PMID:21358741; DOI:10.1038/nrd3373.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 221-237
-
-
Kepp, O.1
Galluzzi, L.2
Lipinski, M.3
Yuan, J.4
Kroemer, G.5
-
26
-
-
78049427830
-
Tumor antigen-targeted, monoclonal antibody-based immunotherapy: Clinical response, cellular immunity and immunoescape
-
PMID:20697078; DOI:10.1200/JCO.2009.27.6360
-
Ferris RL, Jaffee EM, Ferrone S. Tumor antigen-targeted, monoclonal antibody-based immunotherapy: clinical response, cellular immunity and immunoescape. J Clin Oncol 2010; 28:4390-9; PMID:20697078; DOI:10.1200/JCO.2009. 27.6360.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4390-4399
-
-
Ferris, R.L.1
Jaffee, E.M.2
Ferrone, S.3
-
27
-
-
77953678688
-
Understanding and circumventing resistance to anticancer monoclonal antibodies
-
PMID:20065642; DOI:10.4161/mabs.1.3.8292
-
Reslan L, Dalle S, Dumontet C. Understanding and circumventing resistance to anticancer monoclonal antibodies. MAbs 2009; 1:222-9; PMID:20065642; DOI:10.4161/mabs.1.3.8292.
-
(2009)
MAbs
, vol.1
, pp. 222-229
-
-
Reslan, L.1
Dalle, S.2
Dumontet, C.3
-
28
-
-
79960897860
-
Ten years of progress in vaccination against cancer: The need to counteract cancer evasion by dual targeting in future therapies
-
PMID: 21479639; DOI: 10.1007/s00262-011-0985-7
-
Alpizar YA, Chain B, Collins MK, Greenwood J, Katz D, Stauss HJ, et al. Ten years of progress in vaccination against cancer: the need to counteract cancer evasion by dual targeting in future therapies. Cancer Immunol Immunother 2011; 60:1127-35; PMID: 21479639; DOI: 10.1007/s00262-011-0985-7.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 1127-1135
-
-
Alpizar, Y.A.1
Chain, B.2
Collins, M.K.3
Greenwood, J.4
Katz, D.5
Stauss, H.J.6
-
29
-
-
79959759891
-
EGFR-targeting as a biological therapy: Understanding Nimotuzumab's clinical effects
-
Perez R, Moreno E, Garrido G, Crombet T. EGFR-targeting as a biological therapy: understanding Nimotuzumab's clinical effects. Cancers 2011; 3:2014-31; DOI:10.3390/cancers3022014.
-
(2011)
Cancers
, vol.3
-
-
Perez, R.1
Moreno, E.2
Garrido, G.3
Crombet, T.4
-
30
-
-
65549085367
-
Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: Support for a "vaccinal effect" of rituximab
-
PMID:19196657; DOI:10.1182/blood-2008-10-185280
-
Hilchey SP, Hyrien O, Mosmann TR, Livingstone AM, Friedberg JW, Young F, et al. Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab. Blood 2009; 113:3809-12; PMID:19196657; DOI:10.1182/blood-2008-10-185280.
-
(2009)
Blood
, vol.113
, pp. 3809-3812
-
-
Hilchey, S.P.1
Hyrien, O.2
Mosmann, T.R.3
Livingstone, A.M.4
Friedberg, J.W.5
Young, F.6
-
31
-
-
3042759339
-
7A7 MAb: A new tool for the pre-clinical evaluation of EGFR-based therapies
-
PMID:15312307; DOI:10.1089/1536859041224280
-
Garrido G, Sanchez B, Rodriguez HM, Lorenzano P, Alonso D, Fernandez LE. 7A7 MAb: a new tool for the pre-clinical evaluation of EGFR-based therapies. Hybrid Hybridomics 2004; 23:168-75; PMID:15312307; DOI:10.1089/1536859041224280.
-
(2004)
Hybrid Hybridomics
, vol.23
, pp. 168-175
-
-
Garrido, G.1
Sanchez, B.2
Rodriguez, H.M.3
Lorenzano, P.4
Alonso, D.5
Fernandez, L.E.6
-
32
-
-
34548190981
-
T cells are crucial for the anti-metastatic effect of anti-epidermal growth factor receptor antibodies
-
PMID:17415565; DOI:10.1007/s00262-007-0313-4
-
Garrido G, Lorenzano P, Sanchez B, Beausoleil I, Alonso DF, Perez R, et al. T cells are crucial for the anti-metastatic effect of anti-epidermal growth factor receptor antibodies. Cancer Immunol Immunother 2007; 56:1701-10; PMID:17415565; DOI:10.1007/s00262-007-0313-4.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 1701-1710
-
-
Garrido, G.1
Lorenzano, P.2
Sanchez, B.3
Beausoleil, I.4
Alonso, D.F.5
Perez, R.6
-
33
-
-
0034641931
-
Corpse clearance defines the meaning of cell death
-
PMID:11048729; DOI:10.1038/35037722
-
Savill J, Fadok V. Corpse clearance defines the meaning of cell death. Nature 2000; 407:784-8; PMID:11048729; DOI:10.1038/35037722.
-
(2000)
Nature
, vol.407
, pp. 784-788
-
-
Savill, J.1
Fadok, V.2
-
34
-
-
0036293726
-
An innate sense of danger
-
PMID:12081934; DOI:10.1111/j.1749-6632.2002.tb03118.x
-
Matzinger P. An innate sense of danger. Ann NY Acad Sci 2002; 961:341-2; PMID:12081934; DOI:10.1111/j.1749-6632.2002.tb03118.x.
-
(2002)
Ann NY Acad Sci
, vol.961
, pp. 341-342
-
-
Matzinger, P.1
-
35
-
-
41149118513
-
How dying cells alert the immune system to danger
-
PMID:18340345; DOI:10.1038/nri2215
-
Kono H, Rock KL. How dying cells alert the immune system to danger. Nat Rev Immunol 2008; 8:279-89; PMID:18340345; DOI:10.1038/nri2215.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 279-289
-
-
Kono, H.1
Rock, K.L.2
-
36
-
-
67349124914
-
Immunogenic and tolerogenic cell death
-
PMID:19365408; DOI:10.1038/nri2545
-
Green DR, Ferguson T, Zitvogel L, Kroemer G. Immunogenic and tolerogenic cell death. Nat Rev Immunol 2009; 9:353-63; PMID:19365408; DOI:10.1038/nri2545.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 353-363
-
-
Green, D.R.1
Ferguson, T.2
Zitvogel, L.3
Kroemer, G.4
-
37
-
-
3042774310
-
Immune response against dying tumor cells
-
PMID:15246252; DOI:10.1016/S0065-2776(04)84004-5
-
Zitvogel L, Casares N, Pequignot MO, Chaput N, Albert ML, Kroemer G. Immune response against dying tumor cells. Adv Immunol 2004; 84:131-79; PMID:15246252; DOI:10.1016/S0065-2776(04)84004-5.
-
(2004)
Adv Immunol
, vol.84
, pp. 131-179
-
-
Zitvogel, L.1
Casares, N.2
Pequignot, M.O.3
Chaput, N.4
Albert, M.L.5
Kroemer, G.6
-
38
-
-
0025218791
-
Highly tumor-reactive, internalizing, mouse monoclonal antibodies to Le(y)-related cell surface antigens
-
PMID:1690595
-
Hellström I, Garrigues HJ, Garrigues U, Hellstrom KE. Highly tumor-reactive, internalizing, mouse monoclonal antibodies to Le(y)-related cell surface antigens. Cancer Res 1990; 50:2183-90; PMID:1690595.
-
(1990)
Cancer Res
, vol.50
, pp. 2183-2190
-
-
Hellström, I.1
Garrigues, H.J.2
Garrigues, U.3
Hellstrom, K.E.4
-
39
-
-
0033913754
-
A multi-institutional phase II study of BMS-182248-01 (BR96-doxorubicin conjugate) administered every 21 days in patients with advanced gastric adenocarcinoma
-
PMID:11069223
-
Ajani JA, Kelsen DP, Haller D, Hargraves K, Healey D. A multi-institutional phase II study of BMS-182248-01 (BR96-doxorubicin conjugate) administered every 21 days in patients with advanced gastric adenocarcinoma. Cancer J 2000; 6:78-81; PMID:11069223.
-
(2000)
Cancer J
, vol.6
, pp. 78-81
-
-
Ajani, J.A.1
Kelsen, D.P.2
Haller, D.3
Hargraves, K.4
Healey, D.5
-
40
-
-
0034077405
-
Phase I trial of the anti-Lewis Y drug immunoconjugate BR96-doxorubicin in patients with lewis Y-expressing epithelial tumors
-
PMID:10829049
-
Saleh MN, Sugarman S, Murray J, Ostroff JB, Healey D, Jones D, et al. Phase I trial of the anti-Lewis Y drug immunoconjugate BR96-doxorubicin in patients with lewis Y-expressing epithelial tumors. J Clin Oncol 2000; 18:2282-92; PMID:10829049.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2282-2292
-
-
Saleh, M.N.1
Sugarman, S.2
Murray, J.3
Ostroff, J.B.4
Healey, D.5
Jones, D.6
-
41
-
-
0036793823
-
A phase I trial of the single-chain immunotoxin SGN-10 (BR96 sFv-PE40) in patients with advanced solid tumors
-
PMID:12374676.
-
Posey JA, Khazaeli MB, Bookman MA, Nowrouzi A, Grizzle WE, Thornton J, et al. A phase I trial of the single-chain immunotoxin SGN-10 (BR96 sFv-PE40) in patients with advanced solid tumors. Clin Cancer Res 2002; 8:3092-9; PMID:12374676.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3092-3099
-
-
Posey, J.A.1
Khazaeli, M.B.2
Bookman, M.A.3
Nowrouzi, A.4
Grizzle, W.E.5
Thornton, J.6
-
42
-
-
0027339611
-
Ley specific antibody with potent anti-tumor activity is internalized and degraded in lysosomes
-
PMID:8434651
-
Garrigues J, Garrigues U, Hellstrom I, Hellstrom KE. Ley specific antibody with potent anti-tumor activity is internalized and degraded in lysosomes. Am J Pathol 1993; 142:607-22; PMID:8434651.
-
(1993)
Am J Pathol
, vol.142
, pp. 607-622
-
-
Garrigues, J.1
Garrigues, U.2
Hellstrom, I.3
Hellstrom, K.E.4
-
43
-
-
0029030656
-
A novel type of cell death of lymphocytes induced by a monoclonal antibody without participation of complement
-
PMID:7759995; DOI:10.1084/jem.181.6.2007
-
Matsuoka S, Asano Y, Sano K, Kishimoto H, Yamashita I, Yorifuji H, et al. A novel type of cell death of lymphocytes induced by a monoclonal antibody without participation of complement. J Exp Med 1995; 181:2007-15; PMID:7759995; DOI:10.1084/jem.181.6.2007.
-
(1995)
J Exp Med
, vol.181
, pp. 2007-2015
-
-
Matsuoka, S.1
Asano, Y.2
Sano, K.3
Kishimoto, H.4
Yamashita, I.5
Yorifuji, H.6
-
44
-
-
0030055349
-
Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodies
-
PMID:8697629; DOI:10.1046/j.1365-2249.1996.d01-733.x
-
Bhat NM, Bieber MM, Stevenson FK, Teng NN. Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodies. Clin Exp Immunol 1996; 105:183-90; PMID:8697629; DOI:10.1046/j.1365-2249.1996.d01- 733.x.
-
(1996)
Clin Exp Immunol
, vol.105
, pp. 183-190
-
-
Bhat, N.M.1
Bieber, M.M.2
Stevenson, F.K.3
Teng, N.N.4
-
45
-
-
0030937996
-
Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodies, II
-
PMID:9097924; DOI:10.1046/j.1365-2249.1997.d01-976.x
-
Bhat NM, Bieber MM, Hsu FJ, Chapman CJ, Spellerberg M, Stevenson FK, et al. Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodies, II. Clin Exp Immunol 1997; 108:151-9; PMID:9097924; DOI:10.1046/j.1365-2249.1997.d01-976.x.
-
(1997)
Clin Exp Immunol
, vol.108
, pp. 151-159
-
-
Bhat, N.M.1
Bieber, M.M.2
Hsu, F.J.3
Chapman, C.J.4
Spellerberg, M.5
Stevenson, F.K.6
-
46
-
-
0032568651
-
A cell surface receptor defined by a mAb mediates a unique type of cell death similar to oncosis
-
PMID:9600958; DOI:10.1073/pnas.95.11.6290
-
Zhang C, Xu Y, Gu J, Schlossman SF. A cell surface receptor defined by a mAb mediates a unique type of cell death similar to oncosis. Proc Natl Acad Sci USA 1998; 95:6290-5; PMID:9600958; DOI:10.1073/pnas.95.11.6290.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6290-6295
-
-
Zhang, C.1
Xu, Y.2
Gu, J.3
Schlossman, S.F.4
-
47
-
-
0035859894
-
Molecular cloning of Porimin, a novel cell surface receptor mediating oncotic cell death
-
PMID:11481458; DOI:10.1073/pnas.171322898
-
Ma F, Zhang C, Prasad KV, Freeman GJ, Schlossman SF. Molecular cloning of Porimin, a novel cell surface receptor mediating oncotic cell death. Proc Natl Acad Sci USA 2001; 98:9778-83; PMID:11481458; DOI:10.1073/pnas.171322898.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9778-9783
-
-
Ma, F.1
Zhang, C.2
Prasad, K.V.3
Freeman, G.J.4
Schlossman, S.F.5
-
48
-
-
34147140962
-
The glycotope-specific RAV12 monoclonal antibody induces oncosis in vitro and has antitumor activity against gastrointestinal adenocarcinoma tumor xenografts in vivo
-
PMID:17363480; DOI:10.1158/1535-7163.MCT-06-0581
-
Loo D, Pryer N, Young P, Liang T, Coberly S, King KL, et al. The glycotope-specific RAV12 monoclonal antibody induces oncosis in vitro and has antitumor activity against gastrointestinal adenocarcinoma tumor xenografts in vivo. Mol Cancer Ther 2007; 6:856-65; PMID:17363480; DOI:10.1158/1535-7163.MCT- 06-0581.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 856-865
-
-
Loo, D.1
Pryer, N.2
Young, P.3
Liang, T.4
Coberly, S.5
King, K.L.6
-
49
-
-
69749108893
-
The RAV12 monoclonal antibody recognizes the N-linked glycotope RAAG12: Expression in human normal and tumor tissues
-
PMID:19722746
-
Coberly SK, Chen FZ, Armanini MP, Chen Y, Young PF, Mather JP, et al. The RAV12 monoclonal antibody recognizes the N-linked glycotope RAAG12: expression in human normal and tumor tissues. Arch Pathol Lab Med 2009; 133:1403-12; PMID:19722746.
-
(2009)
Arch Pathol Lab Med
, vol.133
, pp. 1403-1412
-
-
Coberly, S.K.1
Chen, F.Z.2
Armanini, M.P.3
Chen, Y.4
Young, P.F.5
Mather, J.P.6
-
50
-
-
77649093935
-
Phase 1 experience with an anti-glycotope monoclonal antibody, RAV12, in recurrent adenocarcinoma
-
PMID:20179219; DOI:10.1158/1078-0432.CCR-09-2263
-
Burris HA, 3rd, Rosen LS, Rocha-Lima CM, Marshall J, Jones S, Cohen RB, et al. Phase 1 experience with an anti-glycotope monoclonal antibody, RAV12, in recurrent adenocarcinoma. Clin Cancer Res 2010; 16:1673-81; PMID:20179219; DOI:10.1158/1078-0432.CCR-09-2263.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1673-1681
-
-
Burris III, H.A.1
Rosen, L.S.2
Rocha-Lima, C.M.3
Marshall, J.4
Jones, S.5
Cohen, R.B.6
-
51
-
-
48349106268
-
Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin- like protein-1
-
PMID:18356574; DOI:10.1634/stemcells.2007-0576
-
Choo AB, Tan HL, Ang SN, Fong WJ, Chin A, Lo J, et al. Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin- like protein-1. Stem Cells 2008; 26:1454-63; PMID:18356574; DOI:10.1634/stemcells.2007-0576.
-
(2008)
Stem Cells
, vol.26
, pp. 1454-1463
-
-
Choo, A.B.1
Tan, H.L.2
Ang, S.N.3
Fong, W.J.4
Chin, A.5
Lo, J.6
-
52
-
-
69249143719
-
mAb 84, a cytotoxic antibody that kills undifferentiated human embryonic stem cells via oncosis
-
PMID:19544435; DOI:10.1002/stem.109
-
Tan HL, Fong WJ, Lee EH, Yap M, Choo A. mAb 84, a cytotoxic antibody that kills undifferentiated human embryonic stem cells via oncosis. Stem Cells 2009; 27:1792-801; PMID:19544435; DOI:10.1002/stem.109.
-
(2009)
Stem Cells
, vol.27
, pp. 1792-1801
-
-
Tan, H.L.1
Fong, W.J.2
Lee, E.H.3
Yap, M.4
Choo, A.5
-
53
-
-
0033624355
-
A mouse IgG1 monoclonal antibody specific for N-glycolyl GM3 ganglioside recognized breast and melanoma tumors
-
PMID:10952412; DOI:10.1089/02724570050109639
-
Carr A, Mullet A, Mazorra Z, Vazquez AM, Alfonso M, Mesa C, et al. A mouse IgG1 monoclonal antibody specific for N-glycolyl GM3 ganglioside recognized breast and melanoma tumors. Hybridoma 2000; 19:241-7; PMID:10952412; DOI:10.1089/02724570050109639.
-
(2000)
Hybridoma
, vol.19
, pp. 241-247
-
-
Carr, A.1
Mullet, A.2
Mazorra, Z.3
Vazquez, A.M.4
Alfonso, M.5
Mesa, C.6
-
54
-
-
77952369047
-
Colloquium paper: Uniquely human evolution of sialic acid genetics and biology
-
PMID:20445087; DOI:10.1073/pnas.0914634107
-
Varki A. Colloquium paper: uniquely human evolution of sialic acid genetics and biology. Proc Natl Acad Sci USA 2010; 107:8939-46; PMID:20445087; DOI:10.1073/pnas.0914634107.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8939-8946
-
-
Varki, A.1
-
55
-
-
33645237406
-
Clinical evidences of GM3 (NeuGc) ganglioside expression in human breast cancer using the 14F7 monoclonal antibody labelled with (99m)Tc
-
PMID:16322892; DOI:10.1007/s10549-005-9064-0
-
Oliva JP, Valdes Z, Casaco A, Pimentel G, Gonzalez J, Alvarez I, et al. Clinical evidences of GM3 (NeuGc) ganglioside expression in human breast cancer using the 14F7 monoclonal antibody labelled with (99m)Tc. Breast Cancer Res Treat 2006; 96:115-21; PMID:16322892; DOI:10.1007/s10549-005-9064-0.
-
(2006)
Breast Cancer Res Treat
, vol.96
, pp. 115-121
-
-
Oliva, J.P.1
Valdes, Z.2
Casaco, A.3
Pimentel, G.4
Gonzalez, J.5
Alvarez, I.6
-
56
-
-
0029803151
-
Gangliosides expressed in human breast cancer
-
PMID:8912852
-
Marquina G, Waki H, Fernandez LE, Kon K, Carr A, Valiente O, et al. Gangliosides expressed in human breast cancer. Cancer Res 1996; 56:5165-71; PMID:8912852.
-
(1996)
Cancer Res
, vol.56
, pp. 5165-5171
-
-
Marquina, G.1
Waki, H.2
Fernandez, L.E.3
Kon, K.4
Carr, A.5
Valiente, O.6
-
57
-
-
78649379388
-
Immunogenicity and safety of a NeuGcGM3 based cancer vaccine: Results from a controlled study in metastatic breast cancer patients
-
In press; PMID:20855939
-
Mulens V, de la Torre A, Marinello P, Rodriguez R, Cardoso J, Diaz R, et al. Immunogenicity and safety of a NeuGcGM3 based cancer vaccine: Results from a controlled study in metastatic breast cancer patients. Hum Vaccin 2010; In press; PMID:20855939.
-
(2010)
Hum Vaccin
-
-
Mulens, V.1
De La Torre, A.2
Marinello, P.3
Rodriguez, R.4
Cardoso, J.5
Diaz, R.6
-
58
-
-
0036498936
-
An anti-idiotype vaccine elicits a specific response to N-glycolyl sialic acid residues of glycoconjugates in melanoma patients
-
PMID:11859147
-
Alfonso M, Diaz A, Hernandez AM, Perez A, Rodriguez E, Bitton R, et al. An anti-idiotype vaccine elicits a specific response to N-glycolyl sialic acid residues of glycoconjugates in melanoma patients. J Immunol 2002; 168:2523-9; PMID:11859147.
-
(2002)
J Immunol
, vol.168
, pp. 2523-2529
-
-
Alfonso, M.1
Diaz, A.2
Hernandez, A.M.3
Perez, A.4
Rodriguez, E.5
Bitton, R.6
-
59
-
-
0038577172
-
Immune responses in breast cancer patients immunized with an anti-idiotype antibody mimicking NeuGc-containing gangliosides
-
PMID:12763476; DOI:10.1016/S1521-6616(03)00036-6
-
Díaz A, Alfonso M, Alonso R, Saurez G, Troche M, Catala M, et al. Immune responses in breast cancer patients immunized with an anti-idiotype antibody mimicking NeuGc-containing gangliosides. Clin Immunol 2003; 107:80-9; PMID:12763476; DOI:10.1016/S1521-6616(03)00036-6.
-
(2003)
Clin Immunol
, vol.107
, pp. 80-89
-
-
Díaz, A.1
Alfonso, M.2
Alonso, R.3
Saurez, G.4
Troche, M.5
Catala, M.6
-
60
-
-
33646768654
-
Cellular and humoral immune response to N-Glycolyl-GM3 elicited by prolonged immunotherapy with an anti-idiotypic vaccine in high-risk and metastatic breast cancer patients
-
PMID:16531822; DOI:10.1097/01.cji.0000188502.11348.34
-
Guthmann MD, Castro MA, Cinat G, Venier C, Koliren L, Bitton RJ, et al. Cellular and humoral immune response to N-Glycolyl-GM3 elicited by prolonged immunotherapy with an anti-idiotypic vaccine in high-risk and metastatic breast cancer patients. J Immunother 2006; 29:215-23; PMID:16531822; DOI:10.1097/01.cji.0000188502.11348.34.
-
(2006)
J Immunother
, vol.29
, pp. 215-223
-
-
Guthmann, M.D.1
Castro, M.A.2
Cinat, G.3
Venier, C.4
Koliren, L.5
Bitton, R.J.6
-
61
-
-
34247330975
-
Active immunotherapy with 1E10 anti-idiotype vaccine in patients with small cell lung cancer: Report of a phase I trial
-
PMID:17218777; DOI:10.4161/cbt.6.2.3574
-
Neninger E, Diaz RM, de la Torre A, Rives R, Diaz A, Saurez G, et al. Active immunotherapy with 1E10 anti-idiotype vaccine in patients with small cell lung cancer: report of a phase I trial. Cancer Biol Ther 2007; 6:145-50; PMID:17218777; DOI:10.4161/cbt.6.2.3574.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 145-150
-
-
Neninger, E.1
Diaz, R.M.2
De La Torre, A.3
Rives, R.4
Diaz, A.5
Saurez, G.6
-
62
-
-
42549128373
-
1E10 anti-idiotype vaccine in non-small cell lung cancer: Experience in stage IIIb/IV patients
-
PMID:18075301; DOI:10.4161/cbt.6.12.5000
-
Alfonso S, Diaz RM, de la Torre A, Santiesteban E, Aguirre F, Perez K, et al. 1E10 anti-idiotype vaccine in non-small cell lung cancer: experience in stage IIIb/IV patients. Cancer Biol Ther 2007; 6:1847-52; PMID:18075301; DOI:10.4161/cbt.6.12.5000.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 1847-1852
-
-
Alfonso, S.1
Diaz, R.M.2
De La Torre, A.3
Santiesteban, E.4
Aguirre, F.5
Perez, K.6
-
63
-
-
58149456558
-
Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody
-
PMID:18941253
-
Hernández AM, Toledo D, Martinez D, Grinan T, Brito V, Macias A, et al. Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody. J Immunol 2008; 181:6625-34; PMID:18941253.
-
(2008)
J Immunol
, vol.181
, pp. 6625-6634
-
-
Hernández, A.M.1
Toledo, D.2
Martinez, D.3
Grinan, T.4
Brito, V.5
Macias, A.6
-
64
-
-
1242272043
-
Structure and molecular interactions of a unique antitumor antibody specific for N-glycolyl GM3
-
PMID:14627696; DOI:10.1074/jbc.M311693200
-
Krengel U, Olsson LL, Martinez C, Talavera A, Rojas G, Mier E, et al. Structure and molecular interactions of a unique antitumor antibody specific for N-glycolyl GM3. J Biol Chem 2004; 279:5597-603; PMID:14627696; DOI:10.1074/jbc.M311693200.
-
(2004)
J Biol Chem
, vol.279
, pp. 5597-5603
-
-
Krengel, U.1
Olsson, L.L.2
Martinez, C.3
Talavera, A.4
Rojas, G.5
Mier, E.6
-
65
-
-
0037716989
-
In vivo and in vitro anti-tumor effect of 14F7 monoclonal antibody
-
PMID:12573110; DOI:10.1089/153685902321043990
-
Carr A, Mesa C, del Carmen Arango M, Vazquez AM, Fernandez LE. In vivo and in vitro anti-tumor effect of 14F7 monoclonal antibody. Hybrid Hybridomics 2002; 21:463-8; PMID:12573110; DOI:10.1089/153685902321043990.
-
(2002)
Hybrid Hybridomics
, vol.21
, pp. 463-468
-
-
Carr, A.1
Mesa, C.2
Del Carmen Arango, M.3
Vazquez, A.M.4
Fernandez, L.E.5
-
66
-
-
51049099189
-
Anti-ganglioside antibody-induced tumor cell death by loss of membrane integrity
-
PMID:18645013; DOI:10.1158/1535-7163.MCT-08-0222
-
Roque-Navarro L, Chakrabandhu K, de Leon J, Rodriguez S, Toledo C, Carr A, et al. Anti-ganglioside antibody-induced tumor cell death by loss of membrane integrity. Mol Cancer Ther 2008; 7:2033-41; PMID:18645013; DOI:10.1158/1535- 7163.MCT-08-0222.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2033-2041
-
-
Roque-Navarro, L.1
Chakrabandhu, K.2
De Leon, J.3
Rodriguez, S.4
Toledo, C.5
Carr, A.6
-
67
-
-
0034532441
-
Removal of amphipathic epitopes from genetically engineered antibodies: Production of modified immunoglobulins with reduced immunogenicity
-
PMID:11152398; DOI:10.1089/027245700750053959
-
Mateo C, Lombardero J, Moreno E, Morales A, Bombino G, Coloma J, et al. Removal of amphipathic epitopes from genetically engineered antibodies: production of modified immunoglobulins with reduced immunogenicity. Hybridoma 2000; 19:463-71; PMID:11152398; DOI:10.1089/027245700750053959.
-
(2000)
Hybridoma
, vol.19
, pp. 463-471
-
-
Mateo, C.1
Lombardero, J.2
Moreno, E.3
Morales, A.4
Bombino, G.5
Coloma, J.6
-
68
-
-
80054944831
-
A cytotoxic humanized anti-ganglioside antibody produced in a murine cell line defective of N-glycolylated-glycoconjugates
-
In press
-
Fernandez-Marrero Y, Roque-Navarro L, Hernandez T, Dorvignit D, Molina-Perez M, Gonzalez A, et al. A cytotoxic humanized anti-ganglioside antibody produced in a murine cell line defective of N-glycolylated- glycoconjugates. Immunobiology 2011; In press.
-
(2011)
Immunobiology
-
-
Fernandez-Marrero, Y.1
Roque-Navarro, L.2
Hernandez, T.3
Dorvignit, D.4
Molina-Perez, M.5
Gonzalez, A.6
-
69
-
-
0028891783
-
Apoptosis, oncosis and necrosis. An overview of cell death
-
PMID:7856735
-
Majno G, Joris I. Apoptosis, oncosis and necrosis. An overview of cell death. Am J Pathol 1995; 146:3-15; PMID:7856735.
-
(1995)
Am J Pathol
, vol.146
, pp. 3-15
-
-
Majno, G.1
Joris, I.2
-
70
-
-
0042624818
-
A monoclonal antibody to the alpha2 domain of murine major histocompatibility complex class I that specifically kills activated lymphocytes and blocks liver damage in the concanavalin A hepatitis model
-
PMID:12885869; DOI:10.1084/jem.20021301
-
Matsuoka S, Tsurui H, Abe M, Terashima K, Nakamura K, Hamano Y, et al. A monoclonal antibody to the alpha2 domain of murine major histocompatibility complex class I that specifically kills activated lymphocytes and blocks liver damage in the concanavalin A hepatitis model. J Exp Med 2003; 198:497-503; PMID:12885869; DOI:10.1084/jem.20021301.
-
(2003)
J Exp Med
, vol.198
, pp. 497-503
-
-
Matsuoka, S.1
Tsurui, H.2
Abe, M.3
Terashima, K.4
Nakamura, K.5
Hamano, Y.6
-
71
-
-
0036346708
-
ERM proteins and merlin: Integrators at the cell cortex
-
PMID:12154370; DOI:10.1038/nrm882
-
Bretscher A, Edwards K, Fehon RG. ERM proteins and merlin: integrators at the cell cortex. Nat Rev Mol Cell Biol 2002; 3:586-99; PMID:12154370; DOI:10.1038/nrm882.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 586-599
-
-
Bretscher, A.1
Edwards, K.2
Fehon, R.G.3
-
72
-
-
0034954343
-
Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton
-
PMID:11457882
-
Takeda T, McQuistan T, Orlando RA, Farquhar MG. Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton. J Clin Invest 2001; 108:289-301; PMID:11457882.
-
(2001)
J Clin Invest
, vol.108
, pp. 289-301
-
-
Takeda, T.1
McQuistan, T.2
Orlando, R.A.3
Farquhar, M.G.4
-
73
-
-
18844370441
-
Epidermal growth factor receptor and signal transduction: Potential targets for anti-cancer therapy
-
PMID:15846113; DOI:10.1097/00001813-200506000-00003
-
Pal SK, Pegram M. Epidermal growth factor receptor and signal transduction: potential targets for anti-cancer therapy. Anticancer Drugs 2005; 16:483-94; PMID:15846113; DOI:10.1097/00001813-200506000-00003.
-
(2005)
Anticancer Drugs
, vol.16
, pp. 483-494
-
-
Pal, S.K.1
Pegram, M.2
-
74
-
-
67651002042
-
Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation
-
PMID:19584289; DOI:10.1158/0008-5472.CAN-08-4518
-
Talavera A, Friemann R, Gomez-Puerta S, Martinez-Fleites C, Garrido G, Rabasa A, et al. Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation. Cancer Res 2009; 69:5851-9; PMID:19584289; DOI:10.1158/0008-5472.CAN-08-4518.
-
(2009)
Cancer Res
, vol.69
, pp. 5851-5859
-
-
Talavera, A.1
Friemann, R.2
Gomez-Puerta, S.3
Martinez-Fleites, C.4
Garrido, G.5
Rabasa, A.6
-
75
-
-
2442704412
-
Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients
-
PMID:15117987; DOI:10.1200/JCO.2004.03.089
-
Crombet T, Osorio M, Cruz T, Roca C, del Castillo R, Mon R, et al. Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients. J Clin Oncol 2004; 22:1646-54; PMID:15117987; DOI:10.1200/JCO.2004.03.089.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1646-1654
-
-
Crombet, T.1
Osorio, M.2
Cruz, T.3
Roca, C.4
Del Castillo, R.5
Mon, R.6
-
76
-
-
33646434844
-
Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: Report from a phase I/II trial
-
PMID:16575203; DOI:10.4161/cbt.5.4.2522
-
Ramos TC, Figueredo J, Catala M, Gonzalez S, Selva JC, Cruz TM, et al. Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: report from a phase I/II trial. Cancer Biol Ther 2006; 5:375-9; PMID:16575203; DOI:10.4161/cbt.5.4.2522.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 375-379
-
-
Ramos, T.C.1
Figueredo, J.2
Catala, M.3
Gonzalez, S.4
Selva, J.C.5
Cruz, T.M.6
-
77
-
-
77953694219
-
Nimotuzumab plus radiotherapy for unresectable squamous- cell carcinoma of the head and neck
-
PMID:20448462; DOI:10.4161/cbt.9.5.10981
-
Rodríguez MO, Rivero TC, del Castillo Bahi R, Muchuli CR, Bilbao MA, Vinageras EN, et al. Nimotuzumab plus radiotherapy for unresectable squamous- cell carcinoma of the head and neck. Cancer Biol Ther 2010; 9:343-9; PMID:20448462; DOI:10.4161/cbt.9.5.10981.
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 343-349
-
-
Rodríguez, M.O.1
Rivero, T.C.2
Del Castillo Bahi, R.3
Muchuli, C.R.4
Bilbao, M.A.5
Vinageras, E.N.6
-
78
-
-
79951826933
-
Bivalent binding by intermediate affinity of nimotuzumab: A contribution to explain antibody clinical profile
-
PMID:21150278; DOI:10.4161/cbt.11.4.14097
-
Garrido G, Tikhomirov IA, Rabasa A, Yang E, Gracia E, Iznaga N, et al. Bivalent binding by intermediate affinity of nimotuzumab: a contribution to explain antibody clinical profile. Cancer Biol Ther 2011; 11:373-82; PMID:21150278; DOI:10.4161/cbt.11.4.14097.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 373-382
-
-
Garrido, G.1
Tikhomirov, I.A.2
Rabasa, A.3
Yang, E.4
Gracia, E.5
Iznaga, N.6
-
79
-
-
33846469368
-
Insights into the immunogenetic basis of two ganglioside- associated idiotypic networks
-
PMID:17270710; DOI:10.1016/j.imbio.2006.08.005
-
Rodríguez M, Roque-Navarro L, Lopez-Requena A, Moreno E, Mateo de Acosta C, Perez R, et al. Insights into the immunogenetic basis of two ganglioside- associated idiotypic networks. Immunobiology 2007; 212:57-70; PMID:17270710; DOI:10.1016/j.imbio.2006.08.005.
-
(2007)
Immunobiology
, vol.212
, pp. 57-70
-
-
Rodríguez, M.1
Roque-Navarro, L.2
Lopez-Requena, A.3
Moreno, E.4
Mateo De Acosta, C.5
Perez, R.6
-
80
-
-
0029586061
-
Generation of a murine monoclonal antibody specific for N-glycolylneuraminic acid-containing gangliosides that also recognizes sulfated glycolipids
-
PMID:8770642; DOI:10.1089/hyb.1995.14.551
-
Vázquez AM, Alfonso M, Lanne B, Karlsson KA, Carr A, Barroso O, et al. Generation of a murine monoclonal antibody specific for N-glycolylneuraminic acid-containing gangliosides that also recognizes sulfated glycolipids. Hybridoma 1995; 14:551-6; PMID:8770642; DOI:10.1089/hyb.1995.14. 551.
-
(1995)
Hybridoma
, vol.14
, pp. 551-556
-
-
Vázquez, A.M.1
Alfonso, M.2
Lanne, B.3
Karlsson, K.A.4
Carr, A.5
Barroso, O.6
-
81
-
-
0031873737
-
Delineation of the epitope recognized by an antibody specific for N-glycolylneuraminic acid-containing gangliosides
-
PMID:9621110; DOI:10.1093/glycob/ 8.7.695
-
Moreno E, Lanne B, Vazquez AM, Kawashima I, Tai T, Fernandez LE, et al. Delineation of the epitope recognized by an antibody specific for N-glycolylneuraminic acid-containing gangliosides. Glycobiology 1998; 8:695-705; PMID:9621110; DOI:10.1093/glycob/ 8.7.695.
-
(1998)
Glycobiology
, vol.8
, pp. 695-705
-
-
Moreno, E.1
Lanne, B.2
Vazquez, A.M.3
Kawashima, I.4
Tai, T.5
Fernandez, L.E.6
-
82
-
-
0041836099
-
Chimeric anti-N-glycolyl-ganglioside and its anti-idiotypic mAbs: Immunodominance of their variable regions
-
PMID:14511569; DOI:10.1089/153685903322328965
-
López-Requena A, Mateo de Acosta C, Perez A, Valle A, Lombardero J, Sosa K, et al. Chimeric anti-N-glycolyl-ganglioside and its anti-idiotypic mAbs: immunodominance of their variable regions. Hybrid Hybridomics 2003; 22:235-43; PMID:14511569; DOI:10.1089/153685903322328965.
-
(2003)
Hybrid Hybridomics
, vol.22
, pp. 235-243
-
-
López-Requena, A.1
Mateo De Acosta, C.2
Perez, A.3
Valle, A.4
Lombardero, J.5
Sosa, K.6
-
83
-
-
0034761284
-
Immunogenetic analysis of variable regions encoding AB1 and gamma-type AB2 antibodies from the NeuGc-containing ganglioside family
-
PMID:11604106; DOI:10.1089/027245701753179785
-
Perez A, Lombardero J, Mateo C, Mustelier G, Alfonso M, Vazquez AM, et al. Immunogenetic analysis of variable regions encoding AB1 and gamma-type AB2 antibodies from the NeuGc-containing ganglioside family. Hybridoma 2001; 20:211-21; PMID:11604106; DOI:10.1089/027245701753179785.
-
(2001)
Hybridoma
, vol.20
, pp. 211-221
-
-
Perez, A.1
Lombardero, J.2
Mateo, C.3
Mustelier, G.4
Alfonso, M.5
Vazquez, A.M.6
-
84
-
-
79952454125
-
Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody
-
PMID:21306777; DOI:10.1016/j.molimm.2011.01.008
-
Fernández-Marrero Y, Hernandez T, Roque-Navarro L, Talavera A, Moreno E, Grinan T, et al. Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody. Mol Immunol 2011; 48:1059-67; PMID:21306777; DOI:10.1016/j.molimm.2011.01.008.
-
(2011)
Mol Immunol
, vol.48
, pp. 1059-1067
-
-
Fernández-Marrero, Y.1
Hernandez, T.2
Roque-Navarro, L.3
Talavera, A.4
Moreno, E.5
Grinan, T.6
-
85
-
-
0345016363
-
Chromatin specificity of anti-double-stranded DNA antibodies and a role for Arg residues in the third complementarity- determining region of the heavy chain
-
PMID:14634143
-
Guth AM, Zhang X, Smith D, Detanico T, Wysocki LJ. Chromatin specificity of anti-double-stranded DNA antibodies and a role for Arg residues in the third complementarity- determining region of the heavy chain. J Immunol 2003; 171:6260-6; PMID:14634143.
-
(2003)
J Immunol
, vol.171
, pp. 6260-6266
-
-
Guth, A.M.1
Zhang, X.2
Smith, D.3
Detanico, T.4
Wysocki, L.J.5
-
86
-
-
33645070833
-
The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin
-
PMID:15642142; DOI:10.1186/ar1449
-
Giles I, Lambrianides N, Latchman D, Chen P, Chukwuocha R, Isenberg D, et al. The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin. Arthritis Res Ther 2005; 7:47-56; PMID:15642142; DOI:10.1186/ar1449.
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 47-56
-
-
Giles, I.1
Lambrianides, N.2
Latchman, D.3
Chen, P.4
Chukwuocha, R.5
Isenberg, D.6
-
87
-
-
33746210258
-
Arginine residues are important in determining the binding of human monoclonal antiphospholipid antibodies to clinically relevant antigens
-
PMID:16849482
-
Giles I, Lambrianides N, Pattni N, Faulkes D, Latchman D, Chen P, et al. Arginine residues are important in determining the binding of human monoclonal antiphospholipid antibodies to clinically relevant antigens. J Immunol 2006; 177:1729-36; PMID:16849482.
-
(2006)
J Immunol
, vol.177
, pp. 1729-1736
-
-
Giles, I.1
Lambrianides, N.2
Pattni, N.3
Faulkes, D.4
Latchman, D.5
Chen, P.6
-
88
-
-
33747841617
-
Gangliosides, Ab1 and Ab2 antibodies I. Towards a molecular dissection of an idiotype-anti-idiotype system
-
PMID:16581129
-
López-Requena A, De Acosta CM, Moreno E, Gonzalez M, Puchades Y, Talavera A, et al. Gangliosides, Ab1 and Ab2 antibodies I. Towards a molecular dissection of an idiotype-anti-idiotype system. Mol Immunol 2007; 44:423-33; PMID:16581129.
-
(2007)
Mol Immunol
, vol.44
, pp. 423-433
-
-
López-Requena, A.1
De Acosta, C.M.2
Moreno, E.3
Gonzalez, M.4
Puchades, Y.5
Talavera, A.6
-
89
-
-
70349464667
-
Crystal structure of an anti-ganglioside antibody and modelling of the functional mimicry of its NeuGc-GM3 antigen by an anti-idiotypic antibody
-
PMID:19748674; DOI:10.1016/j.molimm.2009.07.032
-
Talavera A, Eriksson A, Okvist M, Lopez-Requena A, Fernandez-Marrero Y, Perez R, et al. Crystal structure of an anti-ganglioside antibody and modelling of the functional mimicry of its NeuGc-GM3 antigen by an anti-idiotypic antibody. Mol Immunol 2009; 46:3466-75; PMID:19748674; DOI:10.1016/j.molimm. 2009.07.032.
-
(2009)
Mol Immunol
, vol.46
, pp. 3466-3475
-
-
Talavera, A.1
Eriksson, A.2
Okvist, M.3
Lopez-Requena, A.4
Fernandez-Marrero, Y.5
Perez, R.6
-
90
-
-
0032412454
-
Syngeneic anti-idiotypic monoclonal antibodies to an anti-NeuGc- containing ganglioside monoclonal antibody
-
PMID:9890708; DOI:10.1089/hyb.1998.17.527
-
Vázquez AM, Perez A, Hernandez AM, Macias A, Alfonso M, Bombino G, et al. Syngeneic anti-idiotypic monoclonal antibodies to an anti-NeuGc-containing ganglioside monoclonal antibody. Hybridoma 1998; 17:527-34; PMID:9890708; DOI:10.1089/hyb.1998.17.527.
-
(1998)
Hybridoma
, vol.17
, pp. 527-534
-
-
Vázquez, A.M.1
Perez, A.2
Hernandez, A.M.3
Macias, A.4
Alfonso, M.5
Bombino, G.6
-
91
-
-
79953180541
-
Anti-NeuGcGM3 antibodies, actively elicited by idiotypic vaccination in nonsmall cell lung cancer patients, induce tumor cell death by an oncosis-like mechanism
-
PMID:21300821; DOI:10.4049/jimmunol.1000609
-
Hernández AM, Rodriguez N, Gonzalez JE, Reyes E, Rondon T, Grinan T, et al. Anti-NeuGcGM3 antibodies, actively elicited by idiotypic vaccination in nonsmall cell lung cancer patients, induce tumor cell death by an oncosis-like mechanism. J Immunol 2011; 186:3735-44; PMID:21300821; DOI:10.4049/jimmunol.1000609.
-
(2011)
J Immunol
, vol.186
, pp. 3735-3744
-
-
Hernández, A.M.1
Rodriguez, N.2
Gonzalez, J.E.3
Reyes, E.4
Rondon, T.5
Grinan, T.6
-
92
-
-
29644444314
-
A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death
-
PMID:16234248; DOI:10.1074/jbc.M503621200
-
Guo Y, Chen C, Zheng Y, Zhang J, Tao X, Liu S, et al. A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death. J Biol Chem 2005; 280:41940-52; PMID:16234248; DOI:10.1074/jbc.M503621200.
-
(2005)
J Biol Chem
, vol.280
, pp. 41940-41952
-
-
Guo, Y.1
Chen, C.2
Zheng, Y.3
Zhang, J.4
Tao, X.5
Liu, S.6
-
93
-
-
0034482740
-
KILLER/DR5, a novel DNA-damage inducible death receptor gene, links the p53-tumor suppressor to caspase activation and apoptotic death
-
PMID:10810622; DOI:10.1007/0-306-46817-4-13
-
Wu GS, Kim K, el-Deiry WS. KILLER/DR5, a novel DNA-damage inducible death receptor gene, links the p53-tumor suppressor to caspase activation and apoptotic death. Adv Exp Med Biol 2000; 465:143-51; PMID:10810622; DOI:10.1007/0-306-46817-4-13.
-
(2000)
Adv Exp Med Biol
, vol.465
, pp. 143-151
-
-
Wu, G.S.1
Kim, K.2
El-Deiry, W.S.3
-
94
-
-
27144471037
-
Anti-prostate stem cell antigen monoclonal antibody 1G8 induces cell death in vitro and inhibits tumor growth in vivo via a Fc-independent mechanism
-
PMID:16230414; DOI:10.1158/0008-5472.CAN-05-2086
-
Gu Z, Yamashiro J, Kono E, Reiter RE. Anti-prostate stem cell antigen monoclonal antibody 1G8 induces cell death in vitro and inhibits tumor growth in vivo via a Fc-independent mechanism. Cancer Res 2005; 65:9495-500; PMID:16230414; DOI:10.1158/0008-5472.CAN-05-2086.
-
(2005)
Cancer Res
, vol.65
, pp. 9495-9500
-
-
Gu, Z.1
Yamashiro, J.2
Kono, E.3
Reiter, R.E.4
-
95
-
-
31444453579
-
Alemtuzumab induces caspase-independent cell death in human chronic lymphocytic leukemia cells through a lipid raft-dependent mechanism
-
PMID:16341049; DOI:10.1038/sj.leu.2404014
-
Mone AP, Cheney C, Banks AL, Tridandapani S, Mehter N, Guster S, et al. Alemtuzumab induces caspase-independent cell death in human chronic lymphocytic leukemia cells through a lipid raft-dependent mechanism. Leukemia 2006; 20:272-9; PMID:16341049; DOI:10.1038/sj.leu.2404014.
-
(2006)
Leukemia
, vol.20
, pp. 272-279
-
-
Mone, A.P.1
Cheney, C.2
Banks, A.L.3
Tridandapani, S.4
Mehter, N.5
Guster, S.6
-
96
-
-
81255203382
-
Induction of immunogenic apoptosis by blockade of epidermal growth factor receptor activation with a specific antibody
-
In press; PMID: 21984704; DOI: 10.4049/jimmunol. 1003477
-
Garrido G, Rabasa A, Sánchez B, López MV, Blanco R, López A, et al. Induction of immunogenic apoptosis by blockade of epidermal growth factor receptor activation with a specific antibody. J Immunol 2011; In press; PMID: 21984704; DOI: 10.4049/jimmunol. 1003477.
-
(2011)
J Immunol
-
-
Garrido, G.1
Rabasa, A.2
Sánchez, B.3
López, M.V.4
Blanco, R.5
López, A.6
|