Anti-prostate stem cell antigen monoclonal antibody 1G8 induces cell death in vitro and inhibits tumor growth in vivo via a Fc-independent mechanism

Cancer Research

Volumn 65, Issue 20, 2005, Pages 9495-9500

  Gu, Zhennan ^a   Yamashiro, Joyce ^a   Kono, Evelyn ^a   Reiter, Robert E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; FC RECEPTOR; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1G8; PROSTATE STEM CELL ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CANCER SURVIVAL; CELL DEATH; CONTROLLED STUDY; CROSS LINKING; DRUG MECHANISM; DRUG RECEPTOR BINDING; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE CANCER; RECURRENCE RISK; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; CASPASES; CELL DEATH; CELL GROWTH PROCESSES; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOGLOBULIN FRAGMENTS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, SCID; NEOPLASM PROTEINS; PROSTATIC NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 27144471037     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-2086     Document Type: Article

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