메뉴 건너뛰기




Volumn 20, Issue 2, 2006, Pages 272-279

Alemtuzumab induces caspase-independent cell death in human chronic lymphocytic leukemia cells through a lipid raft-dependent mechanism

Author keywords

Alemtuzumab; Apoptosis; Chronic lymphocyctic luekemia; lipid raft

Indexed keywords

ALEMTUZUMAB; CASPASE; CD52 ANTIGEN; CHOLESTEROL; F ACTIN; GANGLIOSIDE GM1; GLYCOSPHINGOLIPID; IMMUNOGLOBULIN FC FRAGMENT; METHYL BETA CYCLODEXTRIN; TRASTUZUMAB;

EID: 31444453579     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404014     Document Type: Article
Times cited : (104)

References (58)
  • 2
    • 0034765991 scopus 로고    scopus 로고
    • The CD52 antigen and development of the CAMPATH antibodies
    • Hale G. The CD52 antigen and development of the CAMPATH antibodies. Cytotherapy 2001; 3 (3): 137-143.
    • (2001) Cytotherapy , vol.3 , Issue.3 , pp. 137-143
    • Hale, G.1
  • 4
    • 0037441755 scopus 로고    scopus 로고
    • Differential CD52 expression by distinct myeloid dendritic cell subsets: Implications for alemtuzumab activity at the level of antigen presentation in allogeneic graft-host interactions in transplantation
    • Ratzinger G, Reagan JL, Heller G, Busam KJ, Young JW. Differential CD52 expression by distinct myeloid dendritic cell subsets: Implications for alemtuzumab activity at the level of antigen presentation in allogeneic graft-host interactions in transplantation. Blood 2003; 101: 1422-1429.
    • (2003) Blood , vol.101 , pp. 1422-1429
    • Ratzinger, G.1    Reagan, J.L.2    Heller, G.3    Busam, K.J.4    Young, J.W.5
  • 5
    • 0036721489 scopus 로고    scopus 로고
    • Peripheral blood but not tissue dendritic cells express CD52 and are depleted by treatment with alemtuzumab
    • Buggins AG, Mufti GJ, Salisbury J, Codd J, Westwood N, Arno M et al. Peripheral blood but not tissue dendritic cells express CD52 and are depleted by treatment with alemtuzumab. Blood 2002; 100: 1715-1720.
    • (2002) Blood , vol.100 , pp. 1715-1720
    • Buggins, A.G.1    Mufti, G.J.2    Salisbury, J.3    Codd, J.4    Westwood, N.5    Arno, M.6
  • 6
    • 0027462047 scopus 로고
    • The glycosylphosphatidylinositol-anchored lymphocyte antigen CDw52 is associated with the epididymal maturation of human spermatozoa
    • Hale G, Rye PD, Warford A, Lauder I, Brito-Babapulle A. The glycosylphosphatidylinositol-anchored lymphocyte antigen CDw52 is associated with the epididymal maturation of human spermatozoa. J Reprod Immunol 1993; 23: 189-205.
    • (1993) J Reprod Immunol , vol.23 , pp. 189-205
    • Hale, G.1    Rye, P.D.2    Warford, A.3    Lauder, I.4    Brito-Babapulle, A.5
  • 7
    • 0032005642 scopus 로고    scopus 로고
    • Levels of expression of CD52 in normal and leukemic B and T cells: Correlation with in vivo therapeutic responses to Campath-1H
    • Ginaldi L, De Martinis M, Matutes E, Farahat N, Morilla R, Dyer MJ et al. Levels of expression of CD52 in normal and leukemic B and T cells: correlation with in vivo therapeutic responses to Campath-1H. Leuk Res 1998; 22: 185-191.
    • (1998) Leuk Res , vol.22 , pp. 185-191
    • Ginaldi, L.1    De Martinis, M.2    Matutes, E.3    Farahat, N.4    Morilla, R.5    Dyer, M.J.6
  • 8
    • 0024204319 scopus 로고
    • Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H
    • Hale G, Dyer MJ, Clark MR, Phillips JM, Marcus R, Riechmann L et al. Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H. Lancet 1988; 2 (8625): 1394-1399.
    • (1988) Lancet , vol.2 , Issue.8625 , pp. 1394-1399
    • Hale, G.1    Dyer, M.J.2    Clark, M.R.3    Phillips, J.M.4    Marcus, R.5    Riechmann, L.6
  • 10
    • 0030897222 scopus 로고    scopus 로고
    • Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia
    • European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia
    • Osterborg A, Dyer MJ, Bunjes D, Pangalis GA, Bastion Y, Catovsky D et al. Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia* European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia. J Clin Oncol 1997; 15: 1567-1574.
    • (1997) J Clin Oncol , vol.15 , pp. 1567-1574
    • Osterborg, A.1    Dyer, M.J.2    Bunjes, D.3    Pangalis, G.A.4    Bastion, Y.5    Catovsky, D.6
  • 11
    • 0037092951 scopus 로고    scopus 로고
    • Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: Results of a large international study
    • Keating MJ, Flinn I, Jain V, Binet JL, Hillmen P, Byrd J et al. Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: Results of a large international study. Blood 2002; 99: 3554-3561.
    • (2002) Blood , vol.99 , pp. 3554-3561
    • Keating, M.J.1    Flinn, I.2    Jain, V.3    Binet, J.L.4    Hillmen, P.5    Byrd, J.6
  • 12
    • 0026518375 scopus 로고
    • Humanized monoclonal antibody CAMPATH-1H: Myeloma cell expression of genomic constructs, nucleotide sequence of cDNA constructs and comparison of effector mechanisms of myeloma and Chinese hamster ovary cell-derived material
    • Crowe JS, Hall VS, Smith MA, Cooper HJ, Tite JP. Humanized monoclonal antibody CAMPATH-1H: Myeloma cell expression of genomic constructs, nucleotide sequence of cDNA constructs and comparison of effector mechanisms of myeloma and Chinese hamster ovary cell-derived material. Clin Exp Immunol 1992; 87: 105-110.
    • (1992) Clin Exp Immunol , vol.87 , pp. 105-110
    • Crowe, J.S.1    Hall, V.S.2    Smith, M.A.3    Cooper, H.J.4    Tite, J.P.5
  • 13
    • 0020591822 scopus 로고
    • Removal of T cells from bone marrow for transplantation: A monoclonal antilymphocyte antibody that fixes human complement
    • Hale G, Bright S, Chumbley G, Hoang T, Metcalf D, Munro AJ et al. Removal of T cells from bone marrow for transplantation: A monoclonal antilymphocyte antibody that fixes human complement. Blood 1983; 62: 873-882.
    • (1983) Blood , vol.62 , pp. 873-882
    • Hale, G.1    Bright, S.2    Chumbley, G.3    Hoang, T.4    Metcalf, D.5    Munro, A.J.6
  • 14
    • 0027283918 scopus 로고
    • Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen
    • Xia MQ, Hale G, Waldmann H. Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen. Mol Immunol 1993; 30: 1089-1096.
    • (1993) Mol Immunol , vol.30 , pp. 1089-1096
    • Xia, M.Q.1    Hale, G.2    Waldmann, H.3
  • 15
    • 0022357518 scopus 로고
    • Therapeutic potential of rat monoclonal antibodies: Isotype specificity of antibody-dependent cell-mediated cytotoxicity with human lymphocytes
    • Hale G, Clark M, Waldmann H. Therapeutic potential of rat monoclonal antibodies: Isotype specificity of antibody-dependent cell-mediated cytotoxicity with human lymphocytes. J Immunol 1985; 134: 3056-3061.
    • (1985) J Immunol , vol.134 , pp. 3056-3061
    • Hale, G.1    Clark, M.2    Waldmann, H.3
  • 16
    • 0028870425 scopus 로고
    • Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes
    • Rowan WC, Hale G, Tite JP, Brett SJ. Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes. Int Immunol 1995; 7: 69-77.
    • (1995) Int Immunol , vol.7 , pp. 69-77
    • Rowan, W.C.1    Hale, G.2    Tite, J.P.3    Brett, S.J.4
  • 17
    • 0031790767 scopus 로고    scopus 로고
    • Cross-linking of the CAMPATH-1 antigen (CD52) mediates growth inhibition in human B- and T-lymphoma cell lines, and subsequent emergence of CD52-deficient cells
    • Rowan W, Tite J, Topley P, Brett SJ. Cross-linking of the CAMPATH-1 antigen (CD52) mediates growth inhibition in human B- and T-lymphoma cell lines, and subsequent emergence of CD52-deficient cells. Immunology 1998; 95: 427-436.
    • (1998) Immunology , vol.95 , pp. 427-436
    • Rowan, W.1    Tite, J.2    Topley, P.3    Brett, S.J.4
  • 18
    • 1842507429 scopus 로고    scopus 로고
    • Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium
    • Zent CS, Chen JB, Kurten RC, Kaushal GP, Marie Lacy H, Schichman SA. Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium. Leuk Res 2004; 28: 495-507.
    • (2004) Leuk Res , vol.28 , pp. 495-507
    • Zent, C.S.1    Chen, J.B.2    Kurten, R.C.3    Kaushal, G.P.4    Marie Lacy, H.5    Schichman, S.A.6
  • 19
    • 2642578996 scopus 로고    scopus 로고
    • Sensitivity of B-Cell Chronic Lymphocytic Leukemia to Rituximab and Campath-1H and Correlation with the Expression of Cell Cycle Regulatory Proteins
    • Grdisa M. Sensitivity of B-Cell Chronic Lymphocytic Leukemia to Rituximab and Campath-1H and Correlation with the Expression of Cell Cycle Regulatory Proteins. Croat Med J 2004; 45: 136-141.
    • (2004) Croat Med J , vol.45 , pp. 136-141
    • Grdisa, M.1
  • 20
    • 0032030699 scopus 로고    scopus 로고
    • Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies
    • Shan D, Ledbetter JA, Press OW. Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies. Blood 1998; 91: 1644-1652.
    • (1998) Blood , vol.91 , pp. 1644-1652
    • Shan, D.1    Ledbetter, J.A.2    Press, O.W.3
  • 21
    • 0033855194 scopus 로고    scopus 로고
    • Clustered CD20 induced apoptosis: Src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis
    • Hofmeister JK, Cooney D, Coggeshall KM. Clustered CD20 induced apoptosis: Src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis. Blood Cells Mol Dis 2000; 26: 133-143.
    • (2000) Blood Cells Mol Dis , vol.26 , pp. 133-143
    • Hofmeister, J.K.1    Cooney, D.2    Coggeshall, K.M.3
  • 22
    • 0037082469 scopus 로고    scopus 로고
    • The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism
    • Pedersen IM, Buhl AM, Klausen P, Geisler CH, Jurlander J. The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism. Blood 2002; 99: 1314-1319.
    • (2002) Blood , vol.99 , pp. 1314-1319
    • Pedersen, I.M.1    Buhl, A.M.2    Klausen, P.3    Geisler, C.H.4    Jurlander, J.5
  • 23
    • 0036464611 scopus 로고    scopus 로고
    • The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction
    • Byrd JC, Kitada S, Flinn IW, Aron JL, Pearson M, Lucas D et al. The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction. Blood 2002; 99: 1038-1043.
    • (2002) Blood , vol.99 , pp. 1038-1043
    • Byrd, J.C.1    Kitada, S.2    Flinn, I.W.3    Aron, J.L.4    Pearson, M.5    Lucas, D.6
  • 24
    • 0032695010 scopus 로고    scopus 로고
    • CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia
    • Mateo V, Lagneaux L, Bron D, Biron G, Armant M, Delespesse G et al. CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia. Nat Med 1999; 5: 1277-1284.
    • (1999) Nat Med , vol.5 , pp. 1277-1284
    • Mateo, V.1    Lagneaux, L.2    Bron, D.3    Biron, G.4    Armant, M.5    Delespesse, G.6
  • 25
    • 0036346932 scopus 로고    scopus 로고
    • Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells
    • Nagy ZA, Hubner B, Lohning C, Rauchenberger R, Reiffert S, Thomassen-Wolf E, Zahn S et al. Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells. Nat Med 2002; 8: 801-807.
    • (2002) Nat Med , vol.8 , pp. 801-807
    • Nagy, Z.A.1    Hubner, B.2    Lohning, C.3    Rauchenberger, R.4    Reiffert, S.5    Thomassen-Wolf, E.6    Zahn, S.7
  • 26
    • 10744232852 scopus 로고    scopus 로고
    • Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells
    • Mone AP, Huang P, Pelicano H, Cheney CM, Green JM, Tso JY. Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells. Blood 2004; 103: 1846-1854.
    • (2004) Blood , vol.103 , pp. 1846-1854
    • Mone, A.P.1    Huang, P.2    Pelicano, H.3    Cheney, C.M.4    Green, J.M.5    Tso, J.Y.6
  • 27
    • 0035339924 scopus 로고    scopus 로고
    • CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system
    • Suzuki T, Kiyokawa N, Taguchi T, Sekino T, Katagiri YU, Fujimoto J. CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system. J Immunol 2001; 166: 5567-5577.
    • (2001) J Immunol , vol.166 , pp. 5567-5577
    • Suzuki, T.1    Kiyokawa, N.2    Taguchi, T.3    Sekino, T.4    Katagiri, Y.U.5    Fujimoto, J.6
  • 28
    • 0029981025 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
    • Cheson BD, Bennett JM, Grever M, Kay N, Keating MJ, O'Brien S et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment. Blood 1996; 87: 4990-4997.
    • (1996) Blood , vol.87 , pp. 4990-4997
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3    Kay, N.4    Keating, M.J.5    O'Brien, S.6
  • 29
    • 0034847937 scopus 로고    scopus 로고
    • Blood donor leukocyte reduction filters as a source of human B lymphocytes
    • Weitkamp JH, Crowe Jr JE. Blood donor leukocyte reduction filters as a source of human B lymphocytes. Biotechniques 2001; 31: 464-466.
    • (2001) Biotechniques , vol.31 , pp. 464-466
    • Weitkamp, J.H.1    Crowe Jr., J.E.2
  • 30
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman G, Reutelingsperger CP, Kuijten GA, Keehnen RM, Pals ST, van Oers MH. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 1994; 84: 1415-1420.
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.2    Kuijten, G.A.3    Keehnen, R.M.4    Pals, S.T.5    van Oers, M.H.6
  • 31
    • 0037804761 scopus 로고    scopus 로고
    • KRN5500: A novel therapeutic agent with in vitro activity against human B-cell chronic lymphocytic leukemia cells mediates cytotoxicity via the intrinsic pathway of apoptosis
    • Byrd JC, Lucas DM, Mone A, Kitner JB, Drabick JJ, Grever MR. KRN5500: A novel therapeutic agent with in vitro activity against human B-cell chronic lymphocytic leukemia cells mediates cytotoxicity via the intrinsic pathway of apoptosis. Blood 2003; 101: 4547-4550.
    • (2003) Blood , vol.101 , pp. 4547-4550
    • Byrd, J.C.1    Lucas, D.M.2    Mone, A.3    Kitner, J.B.4    Drabick, J.J.5    Grever, M.R.6
  • 32
    • 0032533599 scopus 로고    scopus 로고
    • Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53
    • Byrd JC, Shinn C, Waselenko JK, Fuchs EJ, Lehman TA, Nguyen PL et al. Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53. Blood 1998; 92: 3804-3816.
    • (1998) Blood , vol.92 , pp. 3804-3816
    • Byrd, J.C.1    Shinn, C.2    Waselenko, J.K.3    Fuchs, E.J.4    Lehman, T.A.5    Nguyen, P.L.6
  • 33
    • 0036775527 scopus 로고    scopus 로고
    • Lipid rafts, major histocompatibility complex molecules, and immune regulation
    • Goebel J, Forrest K, Flynn D, Rao R, Roszman TL. Lipid rafts, major histocompatibility complex molecules, and immune regulation. Hum Immunol 2002; 63: 813-820.
    • (2002) Hum Immunol , vol.63 , pp. 813-820
    • Goebel, J.1    Forrest, K.2    Flynn, D.3    Rao, R.4    Roszman, T.L.5
  • 34
    • 0026662674 scopus 로고
    • The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases
    • Cinek T, Horejsi V. The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases. J Immunol 1992; 149: 2262-2270.
    • (1992) J Immunol , vol.149 , pp. 2262-2270
    • Cinek, T.1    Horejsi, V.2
  • 35
    • 0033033321 scopus 로고    scopus 로고
    • Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: Accumulation of actin regulated by local tyrosine phosphorylation
    • Harder T, Simons K. Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation. Eur J Immunol 1999; 29: 556-562.
    • (1999) Eur J Immunol , vol.29 , pp. 556-562
    • Harder, T.1    Simons, K.2
  • 36
    • 0027970448 scopus 로고
    • Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae
    • Fra AM, Williamson E, Simons K, Parton RG. Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae. J Biol Chem 1994; 269: 30745-30748.
    • (1994) J Biol Chem , vol.269 , pp. 30745-30748
    • Fra, A.M.1    Williamson, E.2    Simons, K.3    Parton, R.G.4
  • 37
    • 0031750335 scopus 로고    scopus 로고
    • Lipid domain structure of the plasma membrane revealed by patching of membrane components
    • Harder T, Scheiffele P, Verkade P, Simons K. Lipid domain structure of the plasma membrane revealed by patching of membrane components. J Cell Biol 1998; 141: 929-942.
    • (1998) J Cell Biol , vol.141 , pp. 929-942
    • Harder, T.1    Scheiffele, P.2    Verkade, P.3    Simons, K.4
  • 38
    • 0019986152 scopus 로고
    • Role of membrane gangliosides in the binding and action of bacterial toxins
    • Fishman PH. Role of membrane gangliosides in the binding and action of bacterial toxins. J Membr Biol 1982; 69: 85-97.
    • (1982) J Membr Biol , vol.69 , pp. 85-97
    • Fishman, P.H.1
  • 39
    • 0033431772 scopus 로고    scopus 로고
    • A role for lipid rafts in B cell antigen receptor signaling and antigen targeting
    • Cheng PC, Dykstra ML, Mitchell RN, Pierce SK. A role for lipid rafts in B cell antigen receptor signaling and antigen targeting. J Exp Med 1999; 190: 1549-1560.
    • (1999) J Exp Med , vol.190 , pp. 1549-1560
    • Cheng, P.C.1    Dykstra, M.L.2    Mitchell, R.N.3    Pierce, S.K.4
  • 40
    • 0032727709 scopus 로고    scopus 로고
    • Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor
    • Janes PW, Ley SC, Magee AI. Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor. J Cell Biol 1999; 147: 447-461.
    • (1999) J Cell Biol , vol.147 , pp. 447-461
    • Janes, P.W.1    Ley, S.C.2    Magee, A.I.3
  • 41
    • 0036839104 scopus 로고    scopus 로고
    • Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes
    • Edmonds SD, Ostergaard HL. Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes. J Immunol 2002; 169: 5036-5042.
    • (2002) J Immunol , vol.169 , pp. 5036-5042
    • Edmonds, S.D.1    Ostergaard, H.L.2
  • 42
    • 0035824507 scopus 로고    scopus 로고
    • Fc gamma RIIB1/SHIP-mediated inhibitory signaling in B cells involves lipid rafts
    • Aman MJ, Tosello-Trampont AC, Ravichandran K. Fc gamma RIIB1/ SHIP-mediated inhibitory signaling in B cells involves lipid rafts. J Biol Chem 2001; 276: 46371-46378.
    • (2001) J Biol Chem , vol.276 , pp. 46371-46378
    • Aman, M.J.1    Tosello-Trampont, A.C.2    Ravichandran, K.3
  • 43
    • 0037959071 scopus 로고    scopus 로고
    • The state of lipid rafts: From model membranes to cells
    • Edidin M. The state of lipid rafts: From model membranes to cells. Annu Rev Biophys Biomol Struct 2003; 32: 257-283.
    • (2003) Annu Rev Biophys Biomol Struct , vol.32 , pp. 257-283
    • Edidin, M.1
  • 44
    • 0344585437 scopus 로고    scopus 로고
    • Lipid rafts: Elusive or illusive?
    • Munro S. Lipid rafts: Elusive or illusive? Cell 2003; 115: 377-388.
    • (2003) Cell , vol.115 , pp. 377-388
    • Munro, S.1
  • 45
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K, Ikonen E. Functional rafts in cell membranes. Nature 1997; 387 (6633): 569-572.
    • (1997) Nature , vol.387 , Issue.6633 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 47
    • 0021749841 scopus 로고
    • Direct visualization of redistribution and capping of fluorescent gangliosides on lymphocytes
    • Spiegel S, Kassis S, Wilchek M, Fishman PH. Direct visualization of redistribution and capping of fluorescent gangliosides on lymphocytes. J Cell Biol 1984; 99: 1575-1581.
    • (1984) J Cell Biol , vol.99 , pp. 1575-1581
    • Spiegel, S.1    Kassis, S.2    Wilchek, M.3    Fishman, P.H.4
  • 48
    • 0020803498 scopus 로고
    • Capping of cholera toxin-ganglioside GM1 complexes on mouse lymphocytes is accompanied by co-capping of alpha-actinin
    • Kellie S, Patel B, Pierce EJ, Critchley DR. Capping of cholera toxin-ganglioside GM1 complexes on mouse lymphocytes is accompanied by co-capping of alpha-actinin. J Cell Biol 1983; 97: 447-454.
    • (1983) J Cell Biol , vol.97 , pp. 447-454
    • Kellie, S.1    Patel, B.2    Pierce, E.J.3    Critchley, D.R.4
  • 49
    • 0018184024 scopus 로고
    • Altered membrane-associated functions in chronic lymphocytic leukemia cells
    • Godal T, Henriksen A, Iversen JG, Landaas TO, Lindmo T. Altered membrane-associated functions in chronic lymphocytic leukemia cells. Int J Cancer 1978; 21: 561-569.
    • (1978) Int J Cancer , vol.21 , pp. 561-569
    • Godal, T.1    Henriksen, A.2    Iversen, J.G.3    Landaas, T.O.4    Lindmo, T.5
  • 50
    • 0032559854 scopus 로고    scopus 로고
    • Cholesterol is required for surface transport of influenza virus hemagglutinin
    • Keller P, Simons K. Cholesterol is required for surface transport of influenza virus hemagglutinin. J Cell Biol 1998; 140: 1357-1367.
    • (1998) J Cell Biol , vol.140 , pp. 1357-1367
    • Keller, P.1    Simons, K.2
  • 53
    • 0037108440 scopus 로고    scopus 로고
    • Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: Link between phosphatidylserine exposure and cytoskeleton organization
    • Mateo V, Brown EJ, Biron G, Rubio M, Fischer A, Deist FL et al. Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: Link between phosphatidylserine exposure and cytoskeleton organization. Blood 2002; 100: 2882-2890.
    • (2002) Blood , vol.100 , pp. 2882-2890
    • Mateo, V.1    Brown, E.J.2    Biron, G.3    Rubio, M.4    Fischer, A.5    Deist, F.L.6
  • 54
    • 0036408912 scopus 로고    scopus 로고
    • CD20-mediated apoptosis: Signalling through lipid rafts
    • Deans JP, Li H, Polyak MJ. CD20-mediated apoptosis: Signalling through lipid rafts. Immunology 2002; 107: 176-182.
    • (2002) Immunology , vol.107 , pp. 176-182
    • Deans, J.P.1    Li, H.2    Polyak, M.J.3
  • 56
    • 0037439821 scopus 로고    scopus 로고
    • Anti-CD20 therapeutic antibody rituximab modifies the functional organization of rafts/microdomains of B lymphoma cells
    • Semac I, Palomba C, Kulangara K, Klages N, van Echten-Deckert G, Borisch B et al. Anti-CD20 therapeutic antibody rituximab modifies the functional organization of rafts/microdomains of B lymphoma cells. Cancer Res 2003; 63: 534-540.
    • (2003) Cancer Res , vol.63 , pp. 534-540
    • Semac, I.1    Palomba, C.2    Kulangara, K.3    Klages, N.4    van Echten-Deckert, G.5    Borisch, B.6
  • 57
    • 0142180086 scopus 로고    scopus 로고
    • Store-operated cation entry mediated by CD20 in membrane rafts
    • Li H, Ayer LM, Lytton J, Deans JP. Store-operated cation entry mediated by CD20 in membrane rafts. J Biol Chem 2003; 278: 42427-42434.
    • (2003) J Biol Chem , vol.278 , pp. 42427-42434
    • Li, H.1    Ayer, L.M.2    Lytton, J.3    Deans, J.P.4
  • 58
    • 0037306946 scopus 로고    scopus 로고
    • Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts
    • Craig MS, Morgan SM, Chan HT, Morgan BP, Filatov AV, Johnson PW et al. Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts. Blood 2003; 101: 1045-1052.
    • (2003) Blood , vol.101 , pp. 1045-1052
    • Craig, M.S.1    Morgan, S.M.2    Chan, H.T.3    Morgan, B.P.4    Filatov, A.V.5    Johnson, P.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.