A mouse IgG1 monoclonal antibody specific for N-glycolyl GM3 ganglioside recognized breast and melanoma tumors

Hybridoma

Volumn 19, Issue 3, 2000, Pages 241-247

  Carr, A ^a   Mullet, A ^a   Mazorra, Z ^a   Vazquez A M ^a   Alfonso, M ^a   Mesa, C ^a   Rengifo, E ^a   Perez R ^a   Fernandez L E ^a  

^a CENTER OF MOLECULAR IMMUNOLOGY   (Cuba)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOSIDE GM3; GLYCOLIPID; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 14 F 7; UNCLASSIFIED DRUG; DE N ACETYLNEURAMINYLLACTOSYLCERAMIDE; DE-N-ACETYLNEURAMINYLLACTOSYLCERAMIDE; DRUG DERIVATIVE; IMMUNOGLOBULIN G; N GLYCOLOYLNEURAMINYLLACTOSYLCERAMIDE; N-GLYCOLYLNEURAMINYLLACTOSYLCERAMIDE; TUMOR MARKER; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; BREAST TUMOR; CANCER DIAGNOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; MELANOMA; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; THIN LAYER CHROMATOGRAPHY; TISSUE SPECIFICITY; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; IMMUNOLOGY; METABOLISM;

MURINAE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BREAST NEOPLASMS; CHOLESTEROL, VLDL; FEMALE; G(M3) GANGLIOSIDE; GLYCOLIPIDS; HUMANS; IMMUNOGLOBULIN G; MELANOMA; MICE; MICE, INBRED BALB C; ORGAN SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 0033624355     PISSN: 0272457X     EISSN: None     Source Type: Journal    
DOI: 10.1089/02724570050109639     Document Type: Article

References (39)

1. Glycosphingolipids: Structure, biological source, and properties
2. Possible functions of tumor-associated carbohydrate antigens
3. Mouse monoclonal antibody IgG3 antibody detecting GD3 ganglioside: A phase I trial in patients with malignant melanoma
4. Selection of carbohydrate tumor antigens as targets for immune attack using immunohisto-chemistry. I. Focus on gangliosides
5. Occurrence of sialic acids
6. Chemistry and analysis of sialic acid
7. Quantitative determination of N-glycolylneuraminic acid expression in human cancerous tissues and avian lymphoma cell lines as a tumor-associated sialic acid by gas chromatography-mass spectometry
8. Detection of gangliosides as N-glycolylneuraminic acid-specific tumor- associated Hanganutziu-Deicher antigen in human retinoblastoma cells
9. Detection of glycoproteins as tumor-associated Hanganutziu-Deicher antigen in human gastric cancer cell line, NUGC4
10. Detection of the Hanganutziu-Deicher antigen in patients with hepatocellular carcinoma
11. Analysis of the expression of N-glycolylneuraminic acid-containing gangliosides in cell and tissues using two human monoclonal antibodies
12. The abnormal occurrence and the differentiation-dependent distribution of N-acetyl and N-glycolyl species of the ganglioside GM2 in human germ cell tumors. A study with specific monoclonal antibodies
13. Gangliosides expressed in human breast cancer
14. Generation of murine monoclonal antibodies specific for N- glycolylneuraminic acid containing gangliosides
15. + T cells producing interleukin 2 and small population of mature thymocytes in mice
16. Generation of murine monoclonal antibody specific for N- glycolylneuraminic acid containing gangliosides that also recognizes sulfated glycolipids
17. Delineation of epitope recognized by an antibody specific for N- glycolylneuraminic acid-containing gangliosides
18. Monoclonal antibody directed to Hanganutziu-Deicher active ganglioside GM2 (NeuGc)
19. Generation of murine monoclonal antibodies that can discriminate N- glycolyl and N-acetyl neuraminic acid residues of GM2 ganglioside
20. Production of monoclonal antibodies directed to Hanganutziu Deicher active ganglioside, N-glycolylneuraminic acid-containing gangliosides
21. Very low density lipoproteins and interleukin 2 enhance the immunogenicity of 9-O-acetyl-GD3 ganglioside in Balb/c mice
22. Isolation of brain stradin, a new type of large molecular tissue component
23. Ganglioside isolation
24. Genetic regulation of GM2 expression in liver mouse
25. T cell-independent B cell response to self-monosialo gangliosides: Primary response monoclonal antibodies
26. Quantitative estimation of sialic acid. II. A colorimetric resorcinol- hydrochoric acid methods
27. Rapid sensitive spectrofotometric methods for quantitative determination of sulfatide
28. Characterization of ganglioside expression in human melanoma cell: Immunological and biochemical analysis
29. Use the avidin-biotin-peroxidase complex (ABC) in immunoperoxidase technique: A comparison between ABC and unlabelled antibody PAP procedures
30. Characterization of ganglioside expression in human melanoma cells: Immunological and biochemical analysis
31. Characterization of N-glycolylneuraminic acid-containing gangliosides as tumor-associated Hanganutziu-Deicher antigen in human colon cancer
32. Specific expression of unusual GM2 ganglioside with Hanganutziu- Deicher antigen activity on human colon cancer
33. Hanganutziu-Deicher type heterophyle antigen-positive cells in human cancer tissues demonstrated by membrane immunofluorescence
34. The breast tumor-associated epitope defined by monoclonal antibody 3E1.2 is an O-linked mucin carbohydrate containing N-glycolyl neuraminic acid
35. Occurrence of tumor associated ganglioside antigens with Hanganutziu Deicher antigenic activity in human melanoma
36. Analysis of the expression of Hanganutziu-Deicher (HD) antigen in human malignant melanoma
37. Immunohisto-chemical detection of heterophile Hanganutziu-Deicher (HD) antigen in human malignant melanoma
38. Reponse de malades atteints de melanome a l'immunisation par oncolisats de melanome au virus de la vaccine
39. Hanganutziu-Deicher (HD) antigen as a possible target for immunotherapy of melanoma