-
1
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P. Inflammation in atherosclerosis. Nature 2002, 420:868-874.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
2
-
-
0034918411
-
The endothelium in sepsis: source of and a target for inflammation
-
Hack C.E., Zeerleder S. The endothelium in sepsis: source of and a target for inflammation. Crit Care Med 2001, 29:S21-S27.
-
(2001)
Crit Care Med
, vol.29
-
-
Hack, C.E.1
Zeerleder, S.2
-
5
-
-
0036962344
-
Role of IFN-gamma in allograft rejection
-
Hidalgo L.G., Halloran P.F. Role of IFN-gamma in allograft rejection. Crit Rev Immunol 2002, 22:317-349.
-
(2002)
Crit Rev Immunol
, vol.22
, pp. 317-349
-
-
Hidalgo, L.G.1
Halloran, P.F.2
-
6
-
-
27744456908
-
Gamma interferon: a central mediator in atherosclerosis
-
Leon M.L., Zuckerman S.H. Gamma interferon: a central mediator in atherosclerosis. Inflamm Res 2005, 54:395-411.
-
(2005)
Inflamm Res
, vol.54
, pp. 395-411
-
-
Leon, M.L.1
Zuckerman, S.H.2
-
7
-
-
0034642570
-
Interferon-gamma elicits arteriosclerosis in the absence of leukocytes
-
Tellides G., Tereb D.A., Kirkiles-Smith N.C., Kim R.W., Wilson J.H., Schechner J.S., et al. Interferon-gamma elicits arteriosclerosis in the absence of leukocytes. Nature 2000, 403:207-211.
-
(2000)
Nature
, vol.403
, pp. 207-211
-
-
Tellides, G.1
Tereb, D.A.2
Kirkiles-Smith, N.C.3
Kim, R.W.4
Wilson, J.H.5
Schechner, J.S.6
-
8
-
-
63749108516
-
Interferon gamma: a master regulator of atherosclerosis
-
McLaren J.E., Ramji D.P. Interferon gamma: a master regulator of atherosclerosis. Cytokine Growth Factor Rev 2009, 20:125-135.
-
(2009)
Cytokine Growth Factor Rev
, vol.20
, pp. 125-135
-
-
McLaren, J.E.1
Ramji, D.P.2
-
9
-
-
34547099363
-
The interferons: 50 years after their discovery, there is much more to learn
-
Pestka S. The interferons: 50 years after their discovery, there is much more to learn. J Biol Chem 2007, 282:20047-20051.
-
(2007)
J Biol Chem
, vol.282
, pp. 20047-20051
-
-
Pestka, S.1
-
10
-
-
33947583705
-
STAT activation and differential complex formation dictate selectivity of interferon responses
-
Wesoly J., Szweykowska-Kulinska Z., Bluyssen H.A. STAT activation and differential complex formation dictate selectivity of interferon responses. Acta Biochim Pol 2007, 54:27-38.
-
(2007)
Acta Biochim Pol
, vol.54
, pp. 27-38
-
-
Wesoly, J.1
Szweykowska-Kulinska, Z.2
Bluyssen, H.A.3
-
11
-
-
0036731485
-
Stats: transcriptional control and biological impact
-
Levy D.E., Darnell J..E. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002, 3:651-662.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell, J..E.2
-
12
-
-
56949089974
-
IFN gamma signaling-does it mean JAK-STAT?
-
Gough D.J., Levy D.E., Johnstone R.W., Clarke C.J. IFN gamma signaling-does it mean JAK-STAT?. Cytokine Growth Factor Rev 2008, 19:383-394.
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 383-394
-
-
Gough, D.J.1
Levy, D.E.2
Johnstone, R.W.3
Clarke, C.J.4
-
13
-
-
0030183109
-
ISGF3 gamma p48, a specificity switch for interferon activated transcription factors
-
Bluyssen A.R., Durbin J.E., Levy D.E. ISGF3 gamma p48, a specificity switch for interferon activated transcription factors. Cytokine Growth Factor Rev 1996, 7:11-17.
-
(1996)
Cytokine Growth Factor Rev
, vol.7
, pp. 11-17
-
-
Bluyssen, A.R.1
Durbin, J.E.2
Levy, D.E.3
-
14
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
-
Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010, 11:373-384.
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
15
-
-
4344627821
-
Endogenous ligands of Toll-like receptors
-
Tsan M.F., Gao B. Endogenous ligands of Toll-like receptors. J Leukoc Biol 2004, 76:514-519.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 514-519
-
-
Tsan, M.F.1
Gao, B.2
-
16
-
-
33748525930
-
Multiple roles of Toll-like receptor signaling in atherosclerosis
-
Bjorkbacka H. Multiple roles of Toll-like receptor signaling in atherosclerosis. Curr Opin Lipidol 2006, 17:527-533.
-
(2006)
Curr Opin Lipidol
, vol.17
, pp. 527-533
-
-
Bjorkbacka, H.1
-
17
-
-
57649155518
-
Candesartan inhibits Toll-like receptor expression and activity both in vitro and in vivo
-
Dasu M.R., Riosvelasco A.C., Jialal I. Candesartan inhibits Toll-like receptor expression and activity both in vitro and in vivo. Atherosclerosis 2009, 202:76-83.
-
(2009)
Atherosclerosis
, vol.202
, pp. 76-83
-
-
Dasu, M.R.1
Riosvelasco, A.C.2
Jialal, I.3
-
18
-
-
34547535297
-
Mechanisms of disease: Toll-like receptors in cardiovascular disease
-
Frantz S., Ertl G., Bauersachs J. Mechanisms of disease: Toll-like receptors in cardiovascular disease. Nat Clin Pract Cardiovasc Med 2007, 4:444-454.
-
(2007)
Nat Clin Pract Cardiovasc Med
, vol.4
, pp. 444-454
-
-
Frantz, S.1
Ertl, G.2
Bauersachs, J.3
-
19
-
-
0141670818
-
The interferon in TLR signaling: more than just antiviral
-
Hertzog P.J., O'Neill L.A., Hamilton J.A. The interferon in TLR signaling: more than just antiviral. Trends Immunol 2003, 24:534-539.
-
(2003)
Trends Immunol
, vol.24
, pp. 534-539
-
-
Hertzog, P.J.1
O'Neill, L.A.2
Hamilton, J.A.3
-
20
-
-
79957650185
-
STAT1-mediated signal integration between IFN{gamma} and LPS leads to increased EC and SMC activation and monocyte adhesion
-
Sikorski K., Chmielewski S., Przybyl L., et al. STAT1-mediated signal integration between IFN{gamma} and LPS leads to increased EC and SMC activation and monocyte adhesion. Am J Physiol Cell Physiol 2011, 300:C1334-C1337.
-
(2011)
Am J Physiol Cell Physiol
, vol.300
-
-
Sikorski, K.1
Chmielewski, S.2
Przybyl, L.3
-
21
-
-
33747346235
-
Signal integration between IFN gamma and TLR signalling pathways in macrophages
-
Schroder K., Sweet M.J., Hume D.A. Signal integration between IFN gamma and TLR signalling pathways in macrophages. Immunobiology 2006, 211:511-524.
-
(2006)
Immunobiology
, vol.211
, pp. 511-524
-
-
Schroder, K.1
Sweet, M.J.2
Hume, D.A.3
-
22
-
-
34547736572
-
Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation
-
Hu X., Chen J., Wang L., Ivashkiv L.B. Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. J Leukoc Biol 2007, 82:237-243.
-
(2007)
J Leukoc Biol
, vol.82
, pp. 237-243
-
-
Hu, X.1
Chen, J.2
Wang, L.3
Ivashkiv, L.B.4
-
23
-
-
55149093640
-
Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms
-
Hu X., Chakravarty S.D., Ivashkiv L.B. Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms. Immunol Rev 2008, 226:41-56.
-
(2008)
Immunol Rev
, vol.226
, pp. 41-56
-
-
Hu, X.1
Chakravarty, S.D.2
Ivashkiv, L.B.3
-
24
-
-
70349736116
-
Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases
-
Hu X., Ivashkiv L.B. Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases. Immunity 2009, 31:539-550.
-
(2009)
Immunity
, vol.31
, pp. 539-550
-
-
Hu, X.1
Ivashkiv, L.B.2
-
25
-
-
33744539146
-
IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways
-
Zhao J., Kong H.J., Li H., Huang B., Yang M., Zhu C., et al. IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J Biol Chem 2006, 281:10073-10080.
-
(2006)
J Biol Chem
, vol.281
, pp. 10073-10080
-
-
Zhao, J.1
Kong, H.J.2
Li, H.3
Huang, B.4
Yang, M.5
Zhu, C.6
-
26
-
-
33750064259
-
Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program
-
Negishi H., Fujita Y., Yanai H., Sakaguchi S., Ouyang X., Shinohara M., et al. Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program. Proc Natl Acad Sci USA 2006, 103:15136-15141.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15136-15141
-
-
Negishi, H.1
Fujita, Y.2
Yanai, H.3
Sakaguchi, S.4
Ouyang, X.5
Shinohara, M.6
-
27
-
-
42149107512
-
Role of smooth muscle cells in the initiation and early progression of atherosclerosis
-
Doran A.C., Meller N., McNamara C.A. Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler Thromb Vasc Biol 2008, 28:812-819.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 812-819
-
-
Doran, A.C.1
Meller, N.2
McNamara, C.A.3
-
28
-
-
66949136652
-
ICAM-1 signaling in endothelial cells
-
Lawson C., Wolf S. ICAM-1 signaling in endothelial cells. Pharmacol Rep 2009, 61:22-32.
-
(2009)
Pharmacol Rep
, vol.61
, pp. 22-32
-
-
Lawson, C.1
Wolf, S.2
-
29
-
-
33744981802
-
Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells
-
Heller E.A., Liu E., Tager A.M., Yuan Q., Lin A.Y., Ahluwalia N., et al. Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells. Circulation 2006, 113:2301-2312.
-
(2006)
Circulation
, vol.113
, pp. 2301-2312
-
-
Heller, E.A.1
Liu, E.2
Tager, A.M.3
Yuan, Q.4
Lin, A.Y.5
Ahluwalia, N.6
-
30
-
-
0032749367
-
Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells
-
Mach F., Sauty A., Iarossi A.S., Sukhova G.K., Neote K., Libby P., et al. Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells. J Clin Invest 1999, 104:1041-1050.
-
(1999)
J Clin Invest
, vol.104
, pp. 1041-1050
-
-
Mach, F.1
Sauty, A.2
Iarossi, A.S.3
Sukhova, G.K.4
Neote, K.5
Libby, P.6
-
31
-
-
2542478996
-
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
-
Alexander W.S., Hilton D.J. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu Rev Immunol 2004, 22:503-529.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 503-529
-
-
Alexander, W.S.1
Hilton, D.J.2
-
32
-
-
34249660614
-
SOCS proteins, cytokine signalling and immune regulation
-
Yoshimura A., Naka T., Kubo M. SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol 2007, 7:454-465.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 454-465
-
-
Yoshimura, A.1
Naka, T.2
Kubo, M.3
-
33
-
-
77957898185
-
Suppressor of cytokine signaling and accelerated atherosclerosis in kidney disease
-
Wesoly J., Sikorski K., Lee C.K., Bluyssen H.A. Suppressor of cytokine signaling and accelerated atherosclerosis in kidney disease. Acta Biochim Pol 2010, 57:251-260.
-
(2010)
Acta Biochim Pol
, vol.57
, pp. 251-260
-
-
Wesoly, J.1
Sikorski, K.2
Lee, C.K.3
Bluyssen, H.A.4
-
34
-
-
31344467156
-
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
-
Mansell A., Smith R., Doyle S.L., Gray P., Fenner J.E., Crack P.J., et al. Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat Immunol 2006, 7:148-155.
-
(2006)
Nat Immunol
, vol.7
, pp. 148-155
-
-
Mansell, A.1
Smith, R.2
Doyle, S.L.3
Gray, P.4
Fenner, J.E.5
Crack, P.J.6
-
35
-
-
13044276245
-
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice
-
Naka T., Matsumoto T., Narazaki M., Fujimoto M., Morita Y., Ohsawa Y., et al. Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice. Proc Natl Acad Sci USA 1998, 95:15577-15582.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15577-15582
-
-
Naka, T.1
Matsumoto, T.2
Narazaki, M.3
Fujimoto, M.4
Morita, Y.5
Ohsawa, Y.6
-
36
-
-
0032564463
-
Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1
-
Starr R., Metcalf D., Elefanty A.G., Brysha M., Willson T.A., Nicola N.A., et al. Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1. Proc Natl Acad Sci USA 1998, 95:14395-14399.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14395-14399
-
-
Starr, R.1
Metcalf, D.2
Elefanty, A.G.3
Brysha, M.4
Willson, T.A.5
Nicola, N.A.6
-
37
-
-
20244389693
-
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
-
Yasukawa H., Misawa H., Sakamoto H., Masuhara M., Sasaki A., Wakioka T., et al. The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EMBO J 1999, 18:1309-1320.
-
(1999)
EMBO J
, vol.18
, pp. 1309-1320
-
-
Yasukawa, H.1
Misawa, H.2
Sakamoto, H.3
Masuhara, M.4
Sasaki, A.5
Wakioka, T.6
-
38
-
-
0034612271
-
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130
-
Nicholson S.E., De Souza D., Fabri L.J., Corbin J., Willson T.A., Zhang J.G., et al. Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130. Proc Natl Acad Sci USA 2000, 97:6493-6498.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6493-6498
-
-
Nicholson, S.E.1
De Souza, D.2
Fabri, L.J.3
Corbin, J.4
Willson, T.A.5
Zhang, J.G.6
-
39
-
-
0037415694
-
SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation
-
Takahashi Y., Carpino N., Cross J.C., Torres M., Parganas E., Ihle J.N. SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. EMBO J 2003, 22:372-384.
-
(2003)
EMBO J
, vol.22
, pp. 372-384
-
-
Takahashi, Y.1
Carpino, N.2
Cross, J.C.3
Torres, M.4
Parganas, E.5
Ihle, J.N.6
-
40
-
-
1342346569
-
SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling
-
Kimura A., Kinjyo I., Matsumura Y., Mori H., Mashima R., Harada M. SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling. J Biol Chem 2004, 279:6905-6910.
-
(2004)
J Biol Chem
, vol.279
, pp. 6905-6910
-
-
Kimura, A.1
Kinjyo, I.2
Matsumura, Y.3
Mori, H.4
Mashima, R.5
Harada, M.6
-
41
-
-
18744371050
-
SOCS-1 participates in negative regulation of LPS responses
-
Nakagawa R., Naka T., Tsutsui H., Fujimoto M., Kimura A., Abe T., et al. SOCS-1 participates in negative regulation of LPS responses. Immunity 2002, 17:677-687.
-
(2002)
Immunity
, vol.17
, pp. 677-687
-
-
Nakagawa, R.1
Naka, T.2
Tsutsui, H.3
Fujimoto, M.4
Kimura, A.5
Abe, T.6
-
42
-
-
0033520389
-
SOCS3 is essential in the regulation of fetal liver erythropoiesis
-
Marine J.C., McKay C., Wang D., Topham D.J., Parganas E., Nakajima H., et al. SOCS3 is essential in the regulation of fetal liver erythropoiesis. Cell 1999, 98:617-627.
-
(1999)
Cell
, vol.98
, pp. 617-627
-
-
Marine, J.C.1
McKay, C.2
Wang, D.3
Topham, D.J.4
Parganas, E.5
Nakajima, H.6
-
43
-
-
0035979275
-
Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3
-
Roberts A.W., Robb L., Rakar S., Hartley L., Cluse L., Nicola N.A., et al. Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. Proc Natl Acad Sci USA 2001, 98:9324-9329.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9324-9329
-
-
Roberts, A.W.1
Robb, L.2
Rakar, S.3
Hartley, L.4
Cluse, L.5
Nicola, N.A.6
-
44
-
-
0037938816
-
SOCS3 negatively regulates IL-6 signaling in vivo
-
Croker B.A., Krebs D.L., Zhang J.G., Wormald S., Willson T.A., Stanley E.G., et al. SOCS3 negatively regulates IL-6 signaling in vivo. Nat Immunol 2003, 4:540-545.
-
(2003)
Nat Immunol
, vol.4
, pp. 540-545
-
-
Croker, B.A.1
Krebs, D.L.2
Zhang, J.G.3
Wormald, S.4
Willson, T.A.5
Stanley, E.G.6
-
45
-
-
0038614944
-
SOCS3 regulates the plasticity of gp130 signaling
-
Lang R., Pauleau A.L., Parganas E., Takahashi Y., Mages J., Ihle J.N., et al. SOCS3 regulates the plasticity of gp130 signaling. Nat Immunol 2003, 4:546-550.
-
(2003)
Nat Immunol
, vol.4
, pp. 546-550
-
-
Lang, R.1
Pauleau, A.L.2
Parganas, E.3
Takahashi, Y.4
Mages, J.5
Ihle, J.N.6
-
46
-
-
0037600741
-
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
-
Yasukawa H., Ohishi M., Mori H., Murakami M., Chinen T., Aki D., et al. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol 2003, 4:551-556.
-
(2003)
Nat Immunol
, vol.4
, pp. 551-556
-
-
Yasukawa, H.1
Ohishi, M.2
Mori, H.3
Murakami, M.4
Chinen, T.5
Aki, D.6
-
47
-
-
3142723983
-
SOCS3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
-
Mori H., Hanada R., Hanada T., Aki D., Mashima R., Nishinakamura H., et al. SOCS3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity. Nat Med 2004, 10:739-743.
-
(2004)
Nat Med
, vol.10
, pp. 739-743
-
-
Mori, H.1
Hanada, R.2
Hanada, T.3
Aki, D.4
Mashima, R.5
Nishinakamura, H.6
-
48
-
-
10744223693
-
SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis
-
Croker B.A., Metcalf D., Robb L., Wei W., Mifsud S., DiRago L., et al. SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. Immunity 2004, 20:153-165.
-
(2004)
Immunity
, vol.20
, pp. 153-165
-
-
Croker, B.A.1
Metcalf, D.2
Robb, L.3
Wei, W.4
Mifsud, S.5
DiRago, L.6
-
49
-
-
4344680563
-
Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency
-
Chen Y., Chong M.M., Darwiche R., Thomas H.E., Kay T.W. Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency. Am J Pathol 2004, 165:913-921.
-
(2004)
Am J Pathol
, vol.165
, pp. 913-921
-
-
Chen, Y.1
Chong, M.M.2
Darwiche, R.3
Thomas, H.E.4
Kay, T.W.5
-
50
-
-
10744227089
-
Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases
-
Fujimoto M., Tsutsui H., Xinshou O., Tokumoto M., Watanabe D., Shima Y., et al. Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases. Int Immunol 2004, 16:303-314.
-
(2004)
Int Immunol
, vol.16
, pp. 303-314
-
-
Fujimoto, M.1
Tsutsui, H.2
Xinshou, O.3
Tokumoto, M.4
Watanabe, D.5
Shima, Y.6
-
51
-
-
0037443661
-
Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
-
Niemand C., Nimmesgern A., Haan S., Fischer P., Schaper F., Rossaint R., et al. Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. J Immunol 2003, 170:3263-3272.
-
(2003)
J Immunol
, vol.170
, pp. 3263-3272
-
-
Niemand, C.1
Nimmesgern, A.2
Haan, S.3
Fischer, P.4
Schaper, F.5
Rossaint, R.6
-
52
-
-
0035910753
-
CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation
-
Suzuki A., Hanada T., Mitsuyama K., Yoshida T., Kamizono S., Hoshino T., et al. CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation. J Exp Med 2001, 193:471-481.
-
(2001)
J Exp Med
, vol.193
, pp. 471-481
-
-
Suzuki, A.1
Hanada, T.2
Mitsuyama, K.3
Yoshida, T.4
Kamizono, S.5
Hoshino, T.6
-
53
-
-
26444564804
-
Are suppressors of cytokine signaling proteins recently identified in atherosclerosis possible therapeutic targets?
-
Tang J., Raines E.W. Are suppressors of cytokine signaling proteins recently identified in atherosclerosis possible therapeutic targets?. Trends Cardiovasc Med 2005, 15:243-249.
-
(2005)
Trends Cardiovasc Med
, vol.15
, pp. 243-249
-
-
Tang, J.1
Raines, E.W.2
-
54
-
-
0142061115
-
Soluble intercellular adhesion molecule-1 and interleukin-6 levels reflect endothelial dysfunction in patients with primary hypercholesterolaemia treated with atorvastatin
-
Nawawi H., Osman N.S., Annuar R., Khalid B.A., Yusoff K. Soluble intercellular adhesion molecule-1 and interleukin-6 levels reflect endothelial dysfunction in patients with primary hypercholesterolaemia treated with atorvastatin. Atherosclerosis 2003, 169:283-291.
-
(2003)
Atherosclerosis
, vol.169
, pp. 283-291
-
-
Nawawi, H.1
Osman, N.S.2
Annuar, R.3
Khalid, B.A.4
Yusoff, K.5
-
55
-
-
0034791021
-
Endothelial dysfunction and inflammation - is there a link?
-
Stenvinkel P. Endothelial dysfunction and inflammation - is there a link?. Nephrol Dial Transplant 2001, 16:1968-1971.
-
(2001)
Nephrol Dial Transplant
, vol.16
, pp. 1968-1971
-
-
Stenvinkel, P.1
-
56
-
-
0036180204
-
Elevated interleukin-6 predicts progressive carotid artery atherosclerosis in dialysis patients: association with Chlamydia pneumoniae seropositivity
-
Stenvinkel P., Heimburger O., Jogestrand T. Elevated interleukin-6 predicts progressive carotid artery atherosclerosis in dialysis patients: association with Chlamydia pneumoniae seropositivity. Am J Kidney Dis 2002, 39:274-282.
-
(2002)
Am J Kidney Dis
, vol.39
, pp. 274-282
-
-
Stenvinkel, P.1
Heimburger, O.2
Jogestrand, T.3
-
57
-
-
0024404853
-
IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice
-
Aderka D., Le J.M., Vilcek J. IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. J Immunol 1989, 143:3517-3523.
-
(1989)
J Immunol
, vol.143
, pp. 3517-3523
-
-
Aderka, D.1
Le, J.M.2
Vilcek, J.3
-
58
-
-
0032856199
-
Interleukin-6 exacerbates early atherosclerosis in mice
-
Huber S.A., Sakkinen P., Conze D., Hardin N., Tracy R. Interleukin-6 exacerbates early atherosclerosis in mice. Arterioscler Thromb Vasc Biol 1999, 19:2364-2367.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 2364-2367
-
-
Huber, S.A.1
Sakkinen, P.2
Conze, D.3
Hardin, N.4
Tracy, R.5
-
59
-
-
20844449693
-
Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis
-
Schieffer B., Selle T., Hilfiker A., Hilfiker-Kleiner D., Grote K., Tietge U.J., et al. Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis. Circulation 2004, 110:3493-3500.
-
(2004)
Circulation
, vol.110
, pp. 3493-3500
-
-
Schieffer, B.1
Selle, T.2
Hilfiker, A.3
Hilfiker-Kleiner, D.4
Grote, K.5
Tietge, U.J.6
-
60
-
-
0032518415
-
IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses
-
Xing Z., Gauldie J., Cox G., Baumann H., Jordana M., Lei X.F., et al. IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. J Clin Invest 1998, 101:311-320.
-
(1998)
J Clin Invest
, vol.101
, pp. 311-320
-
-
Xing, Z.1
Gauldie, J.2
Cox, G.3
Baumann, H.4
Jordana, M.5
Lei, X.F.6
-
61
-
-
0035571606
-
Immune mechanisms in atherosclerosis
-
Hansson G.K. Immune mechanisms in atherosclerosis. Arterioscler Thromb Vasc Biol 2001, 21:1876-1890.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1876-1890
-
-
Hansson, G.K.1
-
62
-
-
0028211553
-
The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements
-
Yuan J., Wegenka U.M., Lütticken C., Buschmann J., Decker T., Schindler C., et al. The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements. Mol Cell Biol 1994, 14:1657-1668.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1657-1668
-
-
Yuan, J.1
Wegenka, U.M.2
Lütticken, C.3
Buschmann, J.4
Decker, T.5
Schindler, C.6
-
63
-
-
0028922433
-
A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6
-
Guschin D., Rogers N., Briscoe J., Witthuhn B., Watling D., Horn F., et al. A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6. EMBO J 1995, 14:1421-1429.
-
(1995)
EMBO J
, vol.14
, pp. 1421-1429
-
-
Guschin, D.1
Rogers, N.2
Briscoe, J.3
Witthuhn, B.4
Watling, D.5
Horn, F.6
-
64
-
-
0028281794
-
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components
-
Stahl N., Boulton T.G., Farruggella T., Ip N.Y., Davis S., Witthuhn B.A., et al. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. Science 1994, 263:92-95.
-
(1994)
Science
, vol.263
, pp. 92-95
-
-
Stahl, N.1
Boulton, T.G.2
Farruggella, T.3
Ip, N.Y.4
Davis, S.5
Witthuhn, B.A.6
-
65
-
-
0028303977
-
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
-
Akira S., Nishio Y., Inoue M., Wang X.J., Wei S., Matsusaka T., et al. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 1994, 77:63-71.
-
(1994)
Cell
, vol.77
, pp. 63-71
-
-
Akira, S.1
Nishio, Y.2
Inoue, M.3
Wang, X.J.4
Wei, S.5
Matsusaka, T.6
-
66
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich P.C., Behrmann I., Haan S., Hermanns H.M., Muller-Newen G., Schaper F. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 2003, 374:1-20.
-
(2003)
Biochem J
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
Behrmann, I.2
Haan, S.3
Hermanns, H.M.4
Muller-Newen, G.5
Schaper, F.6
-
67
-
-
0035313701
-
The STAT family in cytokine signaling
-
Ihle J.N. The STAT family in cytokine signaling. CurrOpin Cell Biol 2001, 13:211-217.
-
(2001)
CurrOpin Cell Biol
, vol.13
, pp. 211-217
-
-
Ihle, J.N.1
-
68
-
-
32144463144
-
Opposing actions of STAT-1 and STAT-3
-
Stephanou A., Latchman D.S. Opposing actions of STAT-1 and STAT-3. Growth Factors 2005, 23:177-182.
-
(2005)
Growth Factors
, vol.23
, pp. 177-182
-
-
Stephanou, A.1
Latchman, D.S.2
-
69
-
-
0037062503
-
Mutational switch of an IL-6 response to an interferon-gamma-like response
-
Costa-Pereira A.P., Tininini S., Strobl B., Alonzi T., Schlaak J.F., Is'harc H., et al. Mutational switch of an IL-6 response to an interferon-gamma-like response. Proc Natl Acad Sci USA 2002, 99:8043-8047.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8043-8047
-
-
Costa-Pereira, A.P.1
Tininini, S.2
Strobl, B.3
Alonzi, T.4
Schlaak, J.F.5
Is'harc, H.6
-
70
-
-
77955865832
-
IFN gamma-dependent SOCS3 expression inhibits IL-6-induced STAT3 phosphorylation and differentially affects IL-6 mediated transcriptional responses in endothelial cells
-
Bluyssen H.A., Rastmanesh M.M., Tilburgs C., Jie K., Wesseling S., Goumans M.J., et al. IFN gamma-dependent SOCS3 expression inhibits IL-6-induced STAT3 phosphorylation and differentially affects IL-6 mediated transcriptional responses in endothelial cells. Am J Physiol Cell Physiol 2010, 299:C354-C362.
-
(2010)
Am J Physiol Cell Physiol
, vol.299
-
-
Bluyssen, H.A.1
Rastmanesh, M.M.2
Tilburgs, C.3
Jie, K.4
Wesseling, S.5
Goumans, M.J.6
-
71
-
-
0033233214
-
LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages
-
Bode J.G., Nimmesgern A., Schmitz J., Schaper F., Schmitt M., Frisch W., et al. LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. FEBS Lett 1999, 463:365-370.
-
(1999)
FEBS Lett
, vol.463
, pp. 365-370
-
-
Bode, J.G.1
Nimmesgern, A.2
Schmitz, J.3
Schaper, F.4
Schmitt, M.5
Frisch, W.6
-
72
-
-
34250316051
-
Signal transducer and activator of transcription 1 is required for optimal foam cell formation and atherosclerotic lesion development
-
Agrawal S., Febbraio M., Podrez E., Cathcart M.K., Stark G.R., Chisolm G.M. Signal transducer and activator of transcription 1 is required for optimal foam cell formation and atherosclerotic lesion development. Circulation 2007, 115:2939-2947.
-
(2007)
Circulation
, vol.115
, pp. 2939-2947
-
-
Agrawal, S.1
Febbraio, M.2
Podrez, E.3
Cathcart, M.K.4
Stark, G.R.5
Chisolm, G.M.6
-
73
-
-
33746318969
-
STAT-1 and AP-1 decoy oligonucleotide therapy delays acute rejection and prolongs cardiac allograft survival
-
Hölschermann H., Stadlbauer T.H., Wagner A.H., Fingerhuth H., Muth H., Rong S., et al. STAT-1 and AP-1 decoy oligonucleotide therapy delays acute rejection and prolongs cardiac allograft survival. Cardiovasc Res 2006, 71:527-536.
-
(2006)
Cardiovasc Res
, vol.71
, pp. 527-536
-
-
Hölschermann, H.1
Stadlbauer, T.H.2
Wagner, A.H.3
Fingerhuth, H.4
Muth, H.5
Rong, S.6
-
74
-
-
34249067495
-
STAT-1 decoy oligonucleotide improves microcirculation and reduces acute rejection in allogeneic rat small bowel transplants
-
Stojanovic T., Scheele L., Wagner A.H., Middel P., Bedke J., Lautenschläger I., et al. STAT-1 decoy oligonucleotide improves microcirculation and reduces acute rejection in allogeneic rat small bowel transplants. Gene Ther 2007, 14:883-890.
-
(2007)
Gene Ther
, vol.14
, pp. 883-890
-
-
Stojanovic, T.1
Scheele, L.2
Wagner, A.H.3
Middel, P.4
Bedke, J.5
Lautenschläger, I.6
-
75
-
-
0032950743
-
Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling
-
Frank D.A., Mahajan S., Ritz J. Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling. Nat Med 1999, 5:444-447.
-
(1999)
Nat Med
, vol.5
, pp. 444-447
-
-
Frank, D.A.1
Mahajan, S.2
Ritz, J.3
-
76
-
-
34447502104
-
Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation
-
Torella D., Curcio A., Gasparri C., Galuppo V., De Serio D., Surace F.C., et al. Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation. Am J Physiol Heart Circ Physiol 2007, 292:H2935-H2943.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Torella, D.1
Curcio, A.2
Gasparri, C.3
Galuppo, V.4
De Serio, D.5
Surace, F.C.6
-
77
-
-
0036204648
-
Cellular and clinical pharmacology of fludarabine
-
Gandhi V., Plunkett W. Cellular and clinical pharmacology of fludarabine. Clin Pharmacokinet 2002, 41:93-103.
-
(2002)
Clin Pharmacokinet
, vol.41
, pp. 93-103
-
-
Gandhi, V.1
Plunkett, W.2
-
78
-
-
58249128635
-
A novel phenotypic method to determine fludarabine triphosphate accumulation in T-lymphocytes from hematopoietic cell transplantation patients
-
Woodahl E.L., Wang J., Heimfeld S., Sandmaier B.M., O'Donnell P.V., Phillips B., et al. A novel phenotypic method to determine fludarabine triphosphate accumulation in T-lymphocytes from hematopoietic cell transplantation patients. Cancer Chemother Pharmacol 2009, 63:391-401.
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 391-401
-
-
Woodahl, E.L.1
Wang, J.2
Heimfeld, S.3
Sandmaier, B.M.4
O'Donnell, P.V.5
Phillips, B.6
-
79
-
-
0032577678
-
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
-
Chen X., Vinkemeier U., Zhao Y., Jeruzalmi D., Darnell J..E., Kuriyan J. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 1998, 93:827-839.
-
(1998)
Cell
, vol.93
, pp. 827-839
-
-
Chen, X.1
Vinkemeier, U.2
Zhao, Y.3
Jeruzalmi, D.4
Darnell, J..E.5
Kuriyan, J.6
-
80
-
-
33947417336
-
Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications
-
Huang S. Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications. Clin Cancer Res 2007, 13:1362-1366.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1362-1366
-
-
Huang, S.1
-
81
-
-
66449110287
-
DOCK 6: combining techniques to model RNA-small molecule complexes
-
Lang P.T., Brozell S.R., Mukherjee S., Pettersen E.F., Meng E.C., Thomas V., et al. DOCK 6: combining techniques to model RNA-small molecule complexes. RNA 2009, 15:1219-1230.
-
(2009)
RNA
, vol.15
, pp. 1219-1230
-
-
Lang, P.T.1
Brozell, S.R.2
Mukherjee, S.3
Pettersen, E.F.4
Meng, E.C.5
Thomas, V.6
-
82
-
-
34247343346
-
Surflex-Dock 2.1: robust performance from ligand energetic modeling, ring flexibility, and knowledge-based search
-
Jain A.N. Surflex-Dock 2.1: robust performance from ligand energetic modeling, ring flexibility, and knowledge-based search. J Comput Aided Mol Des 2007, 21:281-306.
-
(2007)
J Comput Aided Mol Des
, vol.21
, pp. 281-306
-
-
Jain, A.N.1
|