STAT-1 decoy oligonucleotide improves microcirculation and reduces acute rejection in allogeneic rat small bowel transplants

Gene Therapy

Volumn 14, Issue 11, 2007, Pages 883-890

  Stojanovic, T ^a   Scheele, L ^b   Wagner, A H ^b   Middel, P ^a   Bedke, J ^b   Lautenschlager I ^a   Leister, I ^c   Panzner, S ^a   Hecker, M ^b  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c Novosom AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CD3 ANTIGEN; CD40 ANTIGEN; STAT1 PROTEIN;

ACUTE GRAFT REJECTION; ALLOTRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; BROWN NORWAY RAT; CAPILLARY DENSITY; CELL INFILTRATION; CELL INTERACTION; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; ERYTHROCYTE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE BLOOD FLOW; INTESTINE PERFUSION; INTESTINE TRANSPLANTATION; LEUKOCYTE; LEWIS RAT; LYMPHOCYTIC INFILTRATION; MALE; MICROCIRCULATION; MUTANT; NONHUMAN; NONVIRAL GENE THERAPY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; T LYMPHOCYTE; WESTERN BLOTTING;

ACUTE DISEASE; ANIMALS; ANTIGENS, CD40; APOPTOSIS; BLOOD FLOW VELOCITY; BLOTTING, WESTERN; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; GENE THERAPY; GENETIC ENGINEERING; GRAFT REJECTION; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; INTESTINE, SMALL; LIPOSOMES; MALE; MICROCIRCULATION; MODELS, ANIMAL; MUTATION; OLIGONUCLEOTIDES, ANTISENSE; RANDOM ALLOCATION; RATS; RATS, INBRED BN; RATS, INBRED LEW; STAT1 TRANSCRIPTION FACTOR; TRANSPLANTATION, HOMOLOGOUS;

RATTUS;

EID: 34249067495     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3302931     Document Type: Article

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