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Volumn 21, Issue 12, 2011, Pages 727-735

Epithelial organization, cell polarity and tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

UVOMORULIN;

EID: 80555131518     PISSN: 09628924     EISSN: 18793088     Source Type: Journal    
DOI: 10.1016/j.tcb.2011.06.005     Document Type: Review
Times cited : (193)

References (82)
  • 1
    • 79952506406 scopus 로고    scopus 로고
    • A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins
    • Dickinson D.J., et al. A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins. Science 2011, 331:1336-1339.
    • (2011) Science , vol.331 , pp. 1336-1339
    • Dickinson, D.J.1
  • 2
    • 67650477014 scopus 로고    scopus 로고
    • Tunable interplay between epidermal growth factor and cell-cell contact governs the spatial dynamics of epithelial growth
    • Kim J.H., et al. Tunable interplay between epidermal growth factor and cell-cell contact governs the spatial dynamics of epithelial growth. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:11149-11153.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 11149-11153
    • Kim, J.H.1
  • 3
    • 0242641565 scopus 로고    scopus 로고
    • Scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
    • Brumby A.M., Richardson H.E. scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J. 2003, 22:5769-5779.
    • (2003) EMBO J. , vol.22 , pp. 5769-5779
    • Brumby, A.M.1    Richardson, H.E.2
  • 4
    • 61749087213 scopus 로고    scopus 로고
    • Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila
    • Igaki T., et al. Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila. Dev. Cell 2009, 16:458-465.
    • (2009) Dev. Cell , vol.16 , pp. 458-465
    • Igaki, T.1
  • 5
    • 77955405813 scopus 로고    scopus 로고
    • Upstream regulation of the hippo size control pathway
    • Grusche F.A., et al. Upstream regulation of the hippo size control pathway. Curr. Biol. 2010, 20:R574-R582.
    • (2010) Curr. Biol. , vol.20
    • Grusche, F.A.1
  • 6
    • 67349123408 scopus 로고    scopus 로고
    • Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
    • Sato T., et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 2009, 459:262-265.
    • (2009) Nature , vol.459 , pp. 262-265
    • Sato, T.1
  • 8
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • Stingl J., et al. Purification and unique properties of mammary epithelial stem cells. Nature 2006, 439:993-997.
    • (2006) Nature , vol.439 , pp. 993-997
    • Stingl, J.1
  • 9
    • 30144433093 scopus 로고    scopus 로고
    • Generation of a functional mammary gland from a single stem cell
    • Shackleton M., et al. Generation of a functional mammary gland from a single stem cell. Nature 2006, 439:84-88.
    • (2006) Nature , vol.439 , pp. 84-88
    • Shackleton, M.1
  • 10
    • 39149130360 scopus 로고    scopus 로고
    • Mechanisms of asymmetric stem cell division
    • Knoblich J.A. Mechanisms of asymmetric stem cell division. Cell 2008, 132:583-597.
    • (2008) Cell , vol.132 , pp. 583-597
    • Knoblich, J.A.1
  • 11
    • 79951784680 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote Notch-dependent epidermal differentiation
    • Williams S.E., et al. Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature 2011, 470:353-358.
    • (2011) Nature , vol.470 , pp. 353-358
    • Williams, S.E.1
  • 12
    • 77957223906 scopus 로고    scopus 로고
    • Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
    • Snippert H.J., et al. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell 2010, 143:134-144.
    • (2010) Cell , vol.143 , pp. 134-144
    • Snippert, H.J.1
  • 13
    • 77958485383 scopus 로고    scopus 로고
    • Intestinal stem cell replacement follows a pattern of neutral drift
    • Lopez-Garcia C., et al. Intestinal stem cell replacement follows a pattern of neutral drift. Science 2010, 330:822-825.
    • (2010) Science , vol.330 , pp. 822-825
    • Lopez-Garcia, C.1
  • 14
    • 75349094518 scopus 로고    scopus 로고
    • Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue
    • Quyn A.J., et al. Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue. Cell Stem Cell 2010, 6:175-181.
    • (2010) Cell Stem Cell , vol.6 , pp. 175-181
    • Quyn, A.J.1
  • 15
    • 79952751557 scopus 로고    scopus 로고
    • Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes
    • Schepers A.G., et al. Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes. EMBO J. 2011, 30:1104-1109.
    • (2011) EMBO J. , vol.30 , pp. 1104-1109
    • Schepers, A.G.1
  • 16
    • 78751676408 scopus 로고    scopus 로고
    • Cells of origin in cancer
    • Visvader J.E. Cells of origin in cancer. Nature 2011, 469:314-322.
    • (2011) Nature , vol.469 , pp. 314-322
    • Visvader, J.E.1
  • 17
    • 59049106578 scopus 로고    scopus 로고
    • Crypt stem cells as the cells-of-origin of intestinal cancer
    • Barker N., et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 2009, 457:608-611.
    • (2009) Nature , vol.457 , pp. 608-611
    • Barker, N.1
  • 18
    • 70349438989 scopus 로고    scopus 로고
    • A luminal epithelial stem cell that is a cell of origin for prostate cancer
    • Wang X., et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 2009, 461:495-500.
    • (2009) Nature , vol.461 , pp. 495-500
    • Wang, X.1
  • 19
    • 28444497035 scopus 로고    scopus 로고
    • The contribution of epidermal stem cells to skin cancer
    • Gerdes M.J., Yuspa S.H. The contribution of epidermal stem cells to skin cancer. Stem Cell Rev. 2005, 1:225-231.
    • (2005) Stem Cell Rev. , vol.1 , pp. 225-231
    • Gerdes, M.J.1    Yuspa, S.H.2
  • 20
    • 77956218241 scopus 로고    scopus 로고
    • BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
    • Molyneux G., et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 2010, 7:403-417.
    • (2010) Cell Stem Cell , vol.7 , pp. 403-417
    • Molyneux, G.1
  • 21
    • 68349130357 scopus 로고    scopus 로고
    • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • Lim E., et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat. Med. 2009, 15:907-913.
    • (2009) Nat. Med. , vol.15 , pp. 907-913
    • Lim, E.1
  • 22
    • 79956351015 scopus 로고    scopus 로고
    • Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
    • Chaffer C.L., et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:7950-7955.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 7950-7955
    • Chaffer, C.L.1
  • 23
    • 77649162059 scopus 로고    scopus 로고
    • Direct conversion of fibroblasts to functional neurons by defined factors
    • Vierbuchen T., et al. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 2010, 463:1035-1041.
    • (2010) Nature , vol.463 , pp. 1035-1041
    • Vierbuchen, T.1
  • 24
    • 0028113326 scopus 로고
    • E1a induces the expression of epithelial characteristics
    • Frisch S.M. E1a induces the expression of epithelial characteristics. J. Cell Biol. 1994, 127:1085-1096.
    • (1994) J. Cell Biol. , vol.127 , pp. 1085-1096
    • Frisch, S.M.1
  • 25
    • 77949894769 scopus 로고    scopus 로고
    • P63 in epithelial survival, germ cell surveillance, and neoplasia
    • Crum C.P., McKeon F.D. p63 in epithelial survival, germ cell surveillance, and neoplasia. Annu. Rev. Pathol. 2010, 5:349-371.
    • (2010) Annu. Rev. Pathol. , vol.5 , pp. 349-371
    • Crum, C.P.1    McKeon, F.D.2
  • 26
    • 33847126689 scopus 로고    scopus 로고
    • Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation
    • Asselin-Labat M.L., et al. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat. Cell Biol. 2007, 9:201-209.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 201-209
    • Asselin-Labat, M.L.1
  • 27
    • 33751202983 scopus 로고    scopus 로고
    • GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland
    • Kouros-Mehr H., et al. GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell 2006, 127:1041-1055.
    • (2006) Cell , vol.127 , pp. 1041-1055
    • Kouros-Mehr, H.1
  • 28
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory P.A., et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat. Cell Biol. 2008, 10:593-601.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 593-601
    • Gregory, P.A.1
  • 29
    • 77956230322 scopus 로고    scopus 로고
    • The ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer?
    • Brabletz S., Brabletz T. The ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer?. EMBO Rep. 2010, 11:670-677.
    • (2010) EMBO Rep. , vol.11 , pp. 670-677
    • Brabletz, S.1    Brabletz, T.2
  • 30
    • 39049160267 scopus 로고    scopus 로고
    • The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
    • Spaderna S., et al. The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res. 2008, 68:537-544.
    • (2008) Cancer Res. , vol.68 , pp. 537-544
    • Spaderna, S.1
  • 31
    • 79952283482 scopus 로고    scopus 로고
    • P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • Chang C.J., et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat. Cell Biol. 2011, 13:317-323.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 317-323
    • Chang, C.J.1
  • 32
    • 79551614327 scopus 로고    scopus 로고
    • Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate
    • Proia T.A., et al. Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Cell Stem Cell 2011, 8:149-163.
    • (2011) Cell Stem Cell , vol.8 , pp. 149-163
    • Proia, T.A.1
  • 33
    • 35549001736 scopus 로고    scopus 로고
    • The PAR proteins: fundamental players in animal cell polarization
    • Goldstein B., Macara I.G. The PAR proteins: fundamental players in animal cell polarization. Dev. Cell 2007, 13:609-622.
    • (2007) Dev. Cell , vol.13 , pp. 609-622
    • Goldstein, B.1    Macara, I.G.2
  • 34
    • 77951174042 scopus 로고    scopus 로고
    • LGN regulates mitotic spindle orientation during epithelial morphogenesis
    • Zheng Z., et al. LGN regulates mitotic spindle orientation during epithelial morphogenesis. J. Cell Biol. 2010, 189:275-288.
    • (2010) J. Cell Biol. , vol.189 , pp. 275-288
    • Zheng, Z.1
  • 35
    • 58149191544 scopus 로고    scopus 로고
    • Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
    • Jaffe A.B., et al. Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis. J. Cell Biol. 2008, 183:625-633.
    • (2008) J. Cell Biol. , vol.183 , pp. 625-633
    • Jaffe, A.B.1
  • 36
    • 78049255724 scopus 로고    scopus 로고
    • Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins
    • Hao Y., et al. Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr. Biol. 2010, 20:1809-1818.
    • (2010) Curr. Biol. , vol.20 , pp. 1809-1818
    • Hao, Y.1
  • 37
    • 77952396762 scopus 로고    scopus 로고
    • Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation
    • Qin Y., et al. Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation. J. Cell Biol. 2010, 189:661-669.
    • (2010) J. Cell Biol. , vol.189 , pp. 661-669
    • Qin, Y.1
  • 38
    • 77952356153 scopus 로고    scopus 로고
    • The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis
    • Rodriguez-Fraticelli A.E., et al. The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis. J. Cell Biol. 2010, 189:725-738.
    • (2010) J. Cell Biol. , vol.189 , pp. 725-738
    • Rodriguez-Fraticelli, A.E.1
  • 39
    • 8344271193 scopus 로고    scopus 로고
    • Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins
    • Du Q., Macara I.G. Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell 2004, 119:503-516.
    • (2004) Cell , vol.119 , pp. 503-516
    • Du, Q.1    Macara, I.G.2
  • 40
    • 0037415643 scopus 로고    scopus 로고
    • The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density
    • Balda M.S., et al. The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density. J. Cell Biol. 2003, 160:423-432.
    • (2003) J. Cell Biol. , vol.160 , pp. 423-432
    • Balda, M.S.1
  • 41
    • 79952298459 scopus 로고    scopus 로고
    • Yap1 acts downstream of alpha-catenin to control epidermal proliferation
    • Schlegelmilch K., et al. Yap1 acts downstream of alpha-catenin to control epidermal proliferation. Cell 2011, 144:782-795.
    • (2011) Cell , vol.144 , pp. 782-795
    • Schlegelmilch, K.1
  • 42
    • 79957462240 scopus 로고    scopus 로고
    • α-Catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1
    • Silvis M.R., et al. α-Catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1. Sci. Signal. 2011, 4:ra33.
    • (2011) Sci. Signal. , vol.4
    • Silvis, M.R.1
  • 43
    • 78149476036 scopus 로고    scopus 로고
    • The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex
    • Gladden A.B., et al. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell 2011, 19:727-739.
    • (2011) Dev Cell , vol.19 , pp. 727-739
    • Gladden, A.B.1
  • 44
    • 77957676987 scopus 로고    scopus 로고
    • The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila
    • Chen C.L., et al. The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:15810-15815.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 15810-15815
    • Chen, C.L.1
  • 45
    • 77953738883 scopus 로고    scopus 로고
    • The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
    • Ling C., et al. The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:10532-10537.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 10532-10537
    • Ling, C.1
  • 46
    • 77950485564 scopus 로고    scopus 로고
    • Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms
    • Grzeschik N.A., et al. Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr. Biol. 2010, 20:573-581.
    • (2010) Curr. Biol. , vol.20 , pp. 573-581
    • Grzeschik, N.A.1
  • 47
    • 77950478873 scopus 로고    scopus 로고
    • Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
    • Robinson B.S., et al. Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr. Biol. 2010, 20:582-590.
    • (2010) Curr. Biol. , vol.20 , pp. 582-590
    • Robinson, B.S.1
  • 48
    • 28544438939 scopus 로고    scopus 로고
    • Endocytic control of epithelial polarity and proliferation in Drosophila
    • Lu H., Bilder D. Endocytic control of epithelial polarity and proliferation in Drosophila. Nat. Cell Biol. 2005, 7:1232-1239.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 1232-1239
    • Lu, H.1    Bilder, D.2
  • 49
    • 78649969033 scopus 로고    scopus 로고
    • The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway
    • Varelas X., et al. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway. Dev. Cell 2010, 19:831-844.
    • (2010) Dev. Cell , vol.19 , pp. 831-844
    • Varelas, X.1
  • 50
    • 79955484868 scopus 로고    scopus 로고
    • KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells
    • Yoshihama Y., et al. KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells. Curr. Biol. 2010, 21:705-711.
    • (2010) Curr. Biol. , vol.21 , pp. 705-711
    • Yoshihama, Y.1
  • 51
    • 1842790793 scopus 로고    scopus 로고
    • KIBRA is a novel substrate for protein kinase Czeta
    • Buther K., et al. KIBRA is a novel substrate for protein kinase Czeta. Biochem. Biophys. Res. Commun. 2004, 317:703-707.
    • (2004) Biochem. Biophys. Res. Commun. , vol.317 , pp. 703-707
    • Buther, K.1
  • 52
    • 72949116594 scopus 로고    scopus 로고
    • An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation
    • Rosse C., et al. An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation. PLoS Biol. 2009, 7:e1000235.
    • (2009) PLoS Biol. , vol.7
    • Rosse, C.1
  • 53
    • 39149127944 scopus 로고    scopus 로고
    • KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling
    • Hilton H.N., et al. KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling. Biochim. Biophys. Acta 2008, 1783:383-393.
    • (2008) Biochim. Biophys. Acta , vol.1783 , pp. 383-393
    • Hilton, H.N.1
  • 54
    • 78650512223 scopus 로고    scopus 로고
    • Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
    • Hidalgo-Carcedo C., et al. Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. Nat. Cell Biol. 2010, 13:49-58.
    • (2010) Nat. Cell Biol. , vol.13 , pp. 49-58
    • Hidalgo-Carcedo, C.1
  • 55
    • 77954943975 scopus 로고    scopus 로고
    • ASPP2 regulates epithelial cell polarity through the PAR complex
    • Cong W., et al. ASPP2 regulates epithelial cell polarity through the PAR complex. Curr. Biol. 2010, 20:1408-1414.
    • (2010) Curr. Biol. , vol.20 , pp. 1408-1414
    • Cong, W.1
  • 56
    • 77954905229 scopus 로고    scopus 로고
    • ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development
    • Sottocornola R., et al. ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development. Dev. Cell 2010, 19:126-137.
    • (2010) Dev. Cell , vol.19 , pp. 126-137
    • Sottocornola, R.1
  • 57
    • 79953153876 scopus 로고    scopus 로고
    • PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ
    • Liu C.Y., et al. PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ. J. Biol. Chem. 2011, 286:5558-5566.
    • (2011) J. Biol. Chem. , vol.286 , pp. 5558-5566
    • Liu, C.Y.1
  • 58
    • 78049450251 scopus 로고    scopus 로고
    • Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP
    • Vigneron A.M., et al. Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP. Genes Dev. 2010, 24:2430-2439.
    • (2010) Genes Dev. , vol.24 , pp. 2430-2439
    • Vigneron, A.M.1
  • 59
    • 4043170088 scopus 로고    scopus 로고
    • Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors
    • Bilder D. Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev. 2004, 18:1909-1925.
    • (2004) Genes Dev. , vol.18 , pp. 1909-1925
    • Bilder, D.1
  • 60
    • 23044515147 scopus 로고    scopus 로고
    • Myc, cell competition, and compensatory proliferation
    • Gallant P. Myc, cell competition, and compensatory proliferation. Cancer Res. 2005, 65:6485-6487.
    • (2005) Cancer Res. , vol.65 , pp. 6485-6487
    • Gallant, P.1
  • 61
    • 79952524571 scopus 로고    scopus 로고
    • Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila
    • Ohsawa S., et al. Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila. Dev. Cell 2011, 20:315-328.
    • (2011) Dev. Cell , vol.20 , pp. 315-328
    • Ohsawa, S.1
  • 62
    • 77958492733 scopus 로고    scopus 로고
    • Context-dependent compensatory proliferation in epithelial homeostasis and tumorigenesis
    • Warner S.J., Longmore G.D. Context-dependent compensatory proliferation in epithelial homeostasis and tumorigenesis. Cell Cycle 2010, 9:4037-4038.
    • (2010) Cell Cycle , vol.9 , pp. 4037-4038
    • Warner, S.J.1    Longmore, G.D.2
  • 63
    • 0242666126 scopus 로고    scopus 로고
    • A genetic screen in Drosophila for metastatic behavior
    • Pagliarini R.A., Xu T. A genetic screen in Drosophila for metastatic behavior. Science 2003, 302:1227-1231.
    • (2003) Science , vol.302 , pp. 1227-1231
    • Pagliarini, R.A.1    Xu, T.2
  • 64
    • 75749106942 scopus 로고    scopus 로고
    • Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion
    • Wu M., et al. Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion. Nature 2010, 463:545-548.
    • (2010) Nature , vol.463 , pp. 545-548
    • Wu, M.1
  • 65
    • 79952100961 scopus 로고    scopus 로고
    • Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesis
    • Hogan C., et al. Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesis. Int. J. Biochem. Cell Biol. 2011, 43:496-503.
    • (2011) Int. J. Biochem. Cell Biol. , vol.43 , pp. 496-503
    • Hogan, C.1
  • 66
    • 77955029332 scopus 로고    scopus 로고
    • Involvement of Lgl and Mahjong/VprBP in cell competition
    • Tamori Y., et al. Involvement of Lgl and Mahjong/VprBP in cell competition. PLoS Biol. 2010, 8:e1000422.
    • (2010) PLoS Biol. , vol.8
    • Tamori, Y.1
  • 67
    • 67149106023 scopus 로고    scopus 로고
    • The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis
    • McCaffrey L.M., Macara I.G. The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis. Genes Dev. 2009, 23:1450-1460.
    • (2009) Genes Dev. , vol.23 , pp. 1450-1460
    • McCaffrey, L.M.1    Macara, I.G.2
  • 68
    • 33750505436 scopus 로고    scopus 로고
    • Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control
    • Aranda V., et al. Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nat. Cell Biol. 2006, 8:1235-1245.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1235-1245
    • Aranda, V.1
  • 69
    • 0036278690 scopus 로고    scopus 로고
    • Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept
    • Bocker W., et al. Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept. Lab. Invest. 2002, 82:737-746.
    • (2002) Lab. Invest. , vol.82 , pp. 737-746
    • Bocker, W.1
  • 70
    • 24644490121 scopus 로고    scopus 로고
    • Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer
    • Eder A.M., et al. Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:12519-12524.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 12519-12524
    • Eder, A.M.1
  • 71
    • 54249140140 scopus 로고    scopus 로고
    • The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer
    • Nolan M.E., et al. The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer. Cancer Res. 2008, 68:8201-8209.
    • (2008) Cancer Res. , vol.68 , pp. 8201-8209
    • Nolan, M.E.1
  • 72
    • 56349098933 scopus 로고    scopus 로고
    • Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
    • Zhan L., et al. Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell 2008, 135:865-878.
    • (2008) Cell , vol.135 , pp. 865-878
    • Zhan, L.1
  • 73
    • 56749170093 scopus 로고    scopus 로고
    • Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module
    • Humbert P.O., et al. Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module. Oncogene 2008, 27:6888-6907.
    • (2008) Oncogene , vol.27 , pp. 6888-6907
    • Humbert, P.O.1
  • 74
    • 44449152002 scopus 로고    scopus 로고
    • The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors
    • Kojima Y., et al. The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors. Hum. Pathol. 2008, 39:824-831.
    • (2008) Hum. Pathol. , vol.39 , pp. 824-831
    • Kojima, Y.1
  • 75
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani S.A., et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133:704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1
  • 76
    • 77953217335 scopus 로고    scopus 로고
    • A role for the epithelial microenvironment at tumor boundaries: evidence from Drosophila and human squamous cell carcinomas
    • Vidal M., et al. A role for the epithelial microenvironment at tumor boundaries: evidence from Drosophila and human squamous cell carcinomas. Am. J. Pathol. 2010, 176:3007-3014.
    • (2010) Am. J. Pathol. , vol.176 , pp. 3007-3014
    • Vidal, M.1
  • 77
    • 79953749322 scopus 로고    scopus 로고
    • Self-organizing optic-cup morphogenesis in three-dimensional culture
    • Eiraku M., et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 2011, 472:51-56.
    • (2011) Nature , vol.472 , pp. 51-56
    • Eiraku, M.1
  • 78
    • 78650012935 scopus 로고    scopus 로고
    • Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia
    • Ridky T.W., et al. Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia. Nat. Med. 2010, 16:1450-1455.
    • (2010) Nat. Med. , vol.16 , pp. 1450-1455
    • Ridky, T.W.1
  • 79
    • 0032387652 scopus 로고    scopus 로고
    • Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis
    • Pollack A.L., et al. Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis. Dev. Biol. 1998, 204:64-79.
    • (1998) Dev. Biol. , vol.204 , pp. 64-79
    • Pollack, A.L.1
  • 80
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J., et al. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003, 30:256-268.
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1
  • 81
    • 41449087759 scopus 로고    scopus 로고
    • Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis
    • Martin-Belmonte F., et al. Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Curr. Biol. 2008, 18:507-513.
    • (2008) Curr. Biol. , vol.18 , pp. 507-513
    • Martin-Belmonte, F.1
  • 82
    • 14744289370 scopus 로고    scopus 로고
    • Par-3 controls tight junction assembly through the Rac exchange factor Tiam1
    • Chen X., Macara I.G. Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. Nat. Cell Biol. 2005, 7:262-269.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 262-269
    • Chen, X.1    Macara, I.G.2


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