scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

EMBO Journal

Volumn 22, Issue 21, 2003, Pages 5769-5779

  Brumby, Anthony M ^a   Richardson, Helena E ^b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b NONE

Author keywords

Cell cycle; Cell death; Cell polarity; Cooperative tumorigenesis; Drosophila

Indexed keywords

CYCLIN E; GENE PRODUCT; MUTANT PROTEIN; NOTCH RECEPTOR;

ALLELE; ARTICLE; CANCER; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL CYCLE; CELL DEATH; CELL POLARITY; CONTROLLED STUDY; DROSOPHILA; EYE; GENE ACTIVATION; MAMMAL; MOLECULAR CLONING; MUTATION; NONHUMAN; ONCOGENE RAS; OPTIC DISK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCRIBBLE GENE; TUMOR SUPPRESSOR GENE; WILD TYPE;

ANIMALS; APOPTOSIS; CYCLIN E; DROSOPHILA; DROSOPHILA PROTEINS; EYE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, INSECT; GENES, RAS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MUTATION; NEOPLASMS, EXPERIMENTAL; RECEPTORS, NOTCH; UP-REGULATION;

MAMMALIA;

EID: 0242641565     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg548     Document Type: Article

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