메뉴 건너뛰기




Volumn 19, Issue 5, 2010, Pages 727-739

The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALPHA CATENIN; EZRIN; MERLIN; MOESIN; RADIXIN; TUMOR SUPPRESSOR PROTEIN;

EID: 78149476036     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2010.10.008     Document Type: Article
Times cited : (147)

References (76)
  • 1
    • 0025985299 scopus 로고
    • Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinocytes and non-differentiating keratinocytes
    • Adams J.C., Watt F.M. Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinocytes and non-differentiating keratinocytes. J. Cell Biol. 1991, 115:829-841.
    • (1991) J. Cell Biol. , vol.115 , pp. 829-841
    • Adams, J.C.1    Watt, F.M.2
  • 4
    • 14744289370 scopus 로고    scopus 로고
    • Par-3 controls tight junction assembly through the Rac exchange factor Tiam1
    • Chen X., Macara I.G. Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. Nat. Cell Biol. 2005, 7:262-269.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 262-269
    • Chen, X.1    Macara, I.G.2
  • 5
    • 38949104753 scopus 로고    scopus 로고
    • Localization to the cortical cytoskeleton is necessary for Nf2/merlin-dependent epidermal growth factor receptor silencing
    • Cole B.K., Curto M., Chan A.W., McClatchey A.I. Localization to the cortical cytoskeleton is necessary for Nf2/merlin-dependent epidermal growth factor receptor silencing. Mol. Cell. Biol. 2008, 28:1274-1284.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 1274-1284
    • Cole, B.K.1    Curto, M.2    Chan, A.W.3    McClatchey, A.I.4
  • 7
    • 28344439885 scopus 로고    scopus 로고
    • Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly
    • Drees F., Pokutta S., Yamada S., Nelson W.J., Weis W.I. Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly. Cell 2005, 123:903-915.
    • (2005) Cell , vol.123 , pp. 903-915
    • Drees, F.1    Pokutta, S.2    Yamada, S.3    Nelson, W.J.4    Weis, W.I.5
  • 9
    • 66049129451 scopus 로고    scopus 로고
    • Finding one's niche in the skin
    • Fuchs E. Finding one's niche in the skin. Cell Stem Cell 2009, 4:499-502.
    • (2009) Cell Stem Cell , vol.4 , pp. 499-502
    • Fuchs, E.1
  • 12
    • 35549001736 scopus 로고    scopus 로고
    • The PAR proteins: fundamental players in animal cell polarization
    • Goldstein B., Macara I.G. The PAR proteins: fundamental players in animal cell polarization. Dev. Cell 2007, 13:609-622.
    • (2007) Dev. Cell , vol.13 , pp. 609-622
    • Goldstein, B.1    Macara, I.G.2
  • 13
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion in morphogenesis
    • Gumbiner B.M. Regulation of cadherin-mediated adhesion in morphogenesis. Nat. Rev. Mol. Cell Biol. 2005, 6:622-634.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 622-634
    • Gumbiner, B.M.1
  • 14
    • 30344445706 scopus 로고    scopus 로고
    • The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
    • Hamaratoglu F., Willecke M., Kango-Singh M., Nolo R., Hyun E., Tao C., Jafar-Nejad H., Halder G. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat. Cell Biol. 2006, 8:27-36.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 27-36
    • Hamaratoglu, F.1    Willecke, M.2    Kango-Singh, M.3    Nolo, R.4    Hyun, E.5    Tao, C.6    Jafar-Nejad, H.7    Halder, G.8
  • 15
    • 69649104042 scopus 로고    scopus 로고
    • The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth
    • Hamaratoglu F., Gajewski K., Sansores-Garcia L., Morrison C., Tao C., Halder G. The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth. J. Cell Sci. 2009, 122:2351-2359.
    • (2009) J. Cell Sci. , vol.122 , pp. 2351-2359
    • Hamaratoglu, F.1    Gajewski, K.2    Sansores-Garcia, L.3    Morrison, C.4    Tao, C.5    Halder, G.6
  • 16
    • 0031865846 scopus 로고    scopus 로고
    • Patterned acquisition of skin barrier function during development
    • Hardman M.J., Sisi P., Banbury D.N., Byrne C. Patterned acquisition of skin barrier function during development. Development 1998, 125:1541-1552.
    • (1998) Development , vol.125 , pp. 1541-1552
    • Hardman, M.J.1    Sisi, P.2    Banbury, D.N.3    Byrne, C.4
  • 17
    • 5444257614 scopus 로고    scopus 로고
    • Adherens junction-dependent and -independent steps in the establishment of epithelial cell polarity in Drosophila
    • Harris T.J., Peifer M. Adherens junction-dependent and -independent steps in the establishment of epithelial cell polarity in Drosophila. J. Cell Biol. 2004, 167:135-147.
    • (2004) J. Cell Biol. , vol.167 , pp. 135-147
    • Harris, T.J.1    Peifer, M.2
  • 18
    • 24144443830 scopus 로고    scopus 로고
    • The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila
    • Harris T.J., Peifer M. The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila. J. Cell Biol. 2005, 170:813-823.
    • (2005) J. Cell Biol. , vol.170 , pp. 813-823
    • Harris, T.J.1    Peifer, M.2
  • 19
    • 34247593781 scopus 로고    scopus 로고
    • APKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development
    • Harris T.J., Peifer M. aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development. Dev. Cell 2007, 12:727-738.
    • (2007) Dev. Cell , vol.12 , pp. 727-738
    • Harris, T.J.1    Peifer, M.2
  • 20
    • 77953878405 scopus 로고    scopus 로고
    • Adherens junctions: from molecules to morphogenesis
    • Harris T.J., Tepass U. Adherens junctions: from molecules to morphogenesis. Nat. Rev. Mol. Cell Biol. 2010, 11:502-514.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 502-514
    • Harris, T.J.1    Tepass, U.2
  • 21
    • 39849100440 scopus 로고    scopus 로고
    • Adherens and tight junctions: structure, function and connections to the actin cytoskeleton
    • Hartsock A., Nelson W.J. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim. Biophys. Acta 2008, 1778:660-669.
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 660-669
    • Hartsock, A.1    Nelson, W.J.2
  • 23
    • 0035907041 scopus 로고    scopus 로고
    • Beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
    • Huelsken J., Vogel R., Erdmann B., Cotsarelis G., Birchmeier W. beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 2001, 105:533-545.
    • (2001) Cell , vol.105 , pp. 533-545
    • Huelsken, J.1    Vogel, R.2    Erdmann, B.3    Cotsarelis, G.4    Birchmeier, W.5
  • 25
    • 0030748548 scopus 로고    scopus 로고
    • Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments
    • Itoh M., Nagafuchi A., Moroi S., Tsukita S. Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J. Cell Biol. 1997, 138:181-192.
    • (1997) J. Cell Biol. , vol.138 , pp. 181-192
    • Itoh, M.1    Nagafuchi, A.2    Moroi, S.3    Tsukita, S.4
  • 26
    • 0036228744 scopus 로고    scopus 로고
    • Intercellular adhesion, signalling and the cytoskeleton
    • Jamora C., Fuchs E. Intercellular adhesion, signalling and the cytoskeleton. Nat. Cell Biol. 2002, 4:E101-E108.
    • (2002) Nat. Cell Biol. , vol.4
    • Jamora, C.1    Fuchs, E.2
  • 27
    • 0032998902 scopus 로고    scopus 로고
    • The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis
    • Jensen U.B., Lowell S., Watt F.M. The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis. Development 1999, 126:2409-2418.
    • (1999) Development , vol.126 , pp. 2409-2418
    • Jensen, U.B.1    Lowell, S.2    Watt, F.M.3
  • 28
    • 0037026595 scopus 로고    scopus 로고
    • Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene
    • Johnson K.C., Kissil J.L., Fry J.L., Jacks T. Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene. Oncogene 2002, 21:5990-5997.
    • (2002) Oncogene , vol.21 , pp. 5990-5997
    • Johnson, K.C.1    Kissil, J.L.2    Fry, J.L.3    Jacks, T.4
  • 29
    • 0242298576 scopus 로고    scopus 로고
    • Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1
    • Kissil J.L., Wilker E.W., Johnson K.C., Eckman M.S., Yaffe M.B., Jacks T. Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1. Mol. Cell 2003, 12:841-849.
    • (2003) Mol. Cell , vol.12 , pp. 841-849
    • Kissil, J.L.1    Wilker, E.W.2    Johnson, K.C.3    Eckman, M.S.4    Yaffe, M.B.5    Jacks, T.6
  • 30
    • 0038077566 scopus 로고    scopus 로고
    • NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions
    • Lallemand D., Curto M., Saotome I., Giovannini M., McClatchey A.I. NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions. Genes Dev. 2003, 17:1090-1100.
    • (2003) Genes Dev. , vol.17 , pp. 1090-1100
    • Lallemand, D.1    Curto, M.2    Saotome, I.3    Giovannini, M.4    McClatchey, A.I.5
  • 31
    • 33747834891 scopus 로고    scopus 로고
    • The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size
    • Laprise P., Beronja S., Silva-Gagliardi N.F., Pellikka M., Jensen A.M., McGlade C.J., Tepass U. The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size. Dev. Cell 2006, 11:363-374.
    • (2006) Dev. Cell , vol.11 , pp. 363-374
    • Laprise, P.1    Beronja, S.2    Silva-Gagliardi, N.F.3    Pellikka, M.4    Jensen, A.M.5    McGlade, C.J.6    Tepass, U.7
  • 33
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • Lechler T., Fuchs E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 2005, 437:275-280.
    • (2005) Nature , vol.437 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 34
    • 58249084923 scopus 로고    scopus 로고
    • Alpha-E-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic
    • Lien W.H., Gelfand V.I., Vasioukhin V. Alpha-E-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic. J. Cell Biol. 2008, 183:989-997.
    • (2008) J. Cell Biol. , vol.183 , pp. 989-997
    • Lien, W.H.1    Gelfand, V.I.2    Vasioukhin, V.3
  • 35
    • 55749108541 scopus 로고    scopus 로고
    • Dissecting the role of cadherin-catenin proteins in mammalian epidermis
    • Lien W.H., Stepniak E., Vasioukhin V. Dissecting the role of cadherin-catenin proteins in mammalian epidermis. Proc. Natl. Acad. Sci. USA 2008, 105:15225-15226.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 15225-15226
    • Lien, W.H.1    Stepniak, E.2    Vasioukhin, V.3
  • 36
    • 77953738883 scopus 로고    scopus 로고
    • The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
    • Ling C., Zheng Y., Yin F., Yu J., Huang J., Hong Y., Wu S., Pan D. The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc. Natl. Acad. Sci. USA 2010, 107:10532-10537.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 10532-10537
    • Ling, C.1    Zheng, Y.2    Yin, F.3    Yu, J.4    Huang, J.5    Hong, Y.6    Wu, S.7    Pan, D.8
  • 39
    • 65149104670 scopus 로고    scopus 로고
    • Merlin and the ERM proteins-regulators of receptor distribution and signaling at the cell cortex
    • McClatchey A.I., Fehon R.G. Merlin and the ERM proteins-regulators of receptor distribution and signaling at the cell cortex. Trends Cell Biol. 2009, 19:198-206.
    • (2009) Trends Cell Biol. , vol.19 , pp. 198-206
    • McClatchey, A.I.1    Fehon, R.G.2
  • 40
    • 25844447107 scopus 로고    scopus 로고
    • Membrane organization and tumorigenesis-the NF2 tumor suppressor, Merlin
    • McClatchey A.I., Giovannini M. Membrane organization and tumorigenesis-the NF2 tumor suppressor, Merlin. Genes Dev. 2005, 19:2265-2277.
    • (2005) Genes Dev. , vol.19 , pp. 2265-2277
    • McClatchey, A.I.1    Giovannini, M.2
  • 42
    • 25444486668 scopus 로고    scopus 로고
    • The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex
    • Mertens A.E., Rygiel T.P., Olivo C., van der Kammen R., Collard J.G. The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex. J. Cell Biol. 2005, 170:1029-1037.
    • (2005) J. Cell Biol. , vol.170 , pp. 1029-1037
    • Mertens, A.E.1    Rygiel, T.P.2    Olivo, C.3    van der Kammen, R.4    Collard, J.G.5
  • 43
    • 67249162901 scopus 로고    scopus 로고
    • Cadherin-mediated regulation of tight junctions in stratifying epithelia
    • Michels C., Aghdam S.Y., Niessen C.M. Cadherin-mediated regulation of tight junctions in stratifying epithelia. Ann. N Y Acad. Sci. 2009, 1165:163-168.
    • (2009) Ann. N Y Acad. Sci. , vol.1165 , pp. 163-168
    • Michels, C.1    Aghdam, S.Y.2    Niessen, C.M.3
  • 44
    • 0042232080 scopus 로고    scopus 로고
    • Self-association of PAR-3-mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions
    • Mizuno K., Suzuki A., Hirose T., Kitamura K., Kutsuzawa K., Futaki M., Amano Y., Ohno S. Self-association of PAR-3-mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions. J. Biol. Chem. 2003, 278:31240-31250.
    • (2003) J. Biol. Chem. , vol.278 , pp. 31240-31250
    • Mizuno, K.1    Suzuki, A.2    Hirose, T.3    Kitamura, K.4    Kutsuzawa, K.5    Futaki, M.6    Amano, Y.7    Ohno, S.8
  • 47
    • 69549130809 scopus 로고    scopus 로고
    • Remodeling of the adherens junctions during morphogenesis
    • Nishimura T., Takeichi M. Remodeling of the adherens junctions during morphogenesis. Curr. Top. Dev. Biol. 2009, 89:33-54.
    • (2009) Curr. Top. Dev. Biol. , vol.89 , pp. 33-54
    • Nishimura, T.1    Takeichi, M.2
  • 48
    • 27544514090 scopus 로고    scopus 로고
    • Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
    • Okada T., Lopez-Lago M., Giancotti F.G. Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane. J. Cell Biol. 2005, 171:361-371.
    • (2005) J. Cell Biol. , vol.171 , pp. 361-371
    • Okada, T.1    Lopez-Lago, M.2    Giancotti, F.G.3
  • 51
    • 33746706949 scopus 로고    scopus 로고
    • Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein Btsz
    • Pilot F., Philippe J.M., Lemmers C., Lecuit T. Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein Btsz. Nature 2006, 442:580-584.
    • (2006) Nature , vol.442 , pp. 580-584
    • Pilot, F.1    Philippe, J.M.2    Lemmers, C.3    Lecuit, T.4
  • 52
    • 77950478873 scopus 로고    scopus 로고
    • Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
    • Robinson B.S., Huang J., Hong Y., Moberg K.H. Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr. Biol. 2010, 20:582-590.
    • (2010) Curr. Biol. , vol.20 , pp. 582-590
    • Robinson, B.S.1    Huang, J.2    Hong, Y.3    Moberg, K.H.4
  • 54
    • 36049008482 scopus 로고    scopus 로고
    • The different structures containing tight junction proteins in epidermal and other stratified epithelial cells, including squamous cell metaplasia
    • Schluter H., Moll I., Wolburg H., Franke W.W. The different structures containing tight junction proteins in epidermal and other stratified epithelial cells, including squamous cell metaplasia. Eur. J. Cell Biol. 2007, 86:645-655.
    • (2007) Eur. J. Cell Biol. , vol.86 , pp. 645-655
    • Schluter, H.1    Moll, I.2    Wolburg, H.3    Franke, W.W.4
  • 55
    • 0032813661 scopus 로고    scopus 로고
    • Klf4 is a transcription factor required for establishing the barrier function of the skin
    • Segre J.A., Bauer C., Fuchs E. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat. Genet. 1999, 22:356-360.
    • (1999) Nat. Genet. , vol.22 , pp. 356-360
    • Segre, J.A.1    Bauer, C.2    Fuchs, E.3
  • 58
    • 0037413625 scopus 로고    scopus 로고
    • Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity
    • Speck O., Hughes S.C., Noren N.K., Kulikauskas R.M., Fehon R.G. Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity. Nature 2003, 421:83-87.
    • (2003) Nature , vol.421 , pp. 83-87
    • Speck, O.1    Hughes, S.C.2    Noren, N.K.3    Kulikauskas, R.M.4    Fehon, R.G.5
  • 59
    • 77953283628 scopus 로고    scopus 로고
    • Cell polarity in eggs and epithelia: parallels and diversity
    • St Johnston D., Ahringer J. Cell polarity in eggs and epithelia: parallels and diversity. Cell 2010, 141:757-774.
    • (2010) Cell , vol.141 , pp. 757-774
    • St Johnston, D.1    Ahringer, J.2
  • 60
    • 77249110786 scopus 로고    scopus 로고
    • Dynamics and functions of tight junctions
    • Steed E., Balda M.S., Matter K. Dynamics and functions of tight junctions. Trends Cell Biol. 2010, 20:142-149.
    • (2010) Trends Cell Biol. , vol.20 , pp. 142-149
    • Steed, E.1    Balda, M.S.2    Matter, K.3
  • 61
    • 33645746316 scopus 로고    scopus 로고
    • The PAR-aPKC system: lessons in polarity
    • Suzuki A., Ohno S. The PAR-aPKC system: lessons in polarity. J. Cell Sci. 2006, 119:979-987.
    • (2006) J. Cell Sci. , vol.119 , pp. 979-987
    • Suzuki, A.1    Ohno, S.2
  • 62
    • 0035911955 scopus 로고    scopus 로고
    • Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures
    • Suzuki A., Yamanaka T., Hirose T., Manabe N., Mizuno K., Shimizu M., Akimoto K., Izumi Y., Ohnishi T., Ohno S. Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J. Cell Biol. 2001, 152:1183-1196.
    • (2001) J. Cell Biol. , vol.152 , pp. 1183-1196
    • Suzuki, A.1    Yamanaka, T.2    Hirose, T.3    Manabe, N.4    Mizuno, K.5    Shimizu, M.6    Akimoto, K.7    Izumi, Y.8    Ohnishi, T.9    Ohno, S.10
  • 63
    • 0037106581 scopus 로고    scopus 로고
    • APKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization
    • Suzuki A., Ishiyama C., Hashiba K., Shimizu M., Ebnet K., Ohno S. aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization. J. Cell Sci. 2002, 115:3565-3573.
    • (2002) J. Cell Sci. , vol.115 , pp. 3565-3573
    • Suzuki, A.1    Ishiyama, C.2    Hashiba, K.3    Shimizu, M.4    Ebnet, K.5    Ohno, S.6
  • 64
    • 68949163497 scopus 로고    scopus 로고
    • FERM proteins in animal morphogenesis
    • Tepass U. FERM proteins in animal morphogenesis. Curr. Opin. Genet. Dev. 2009, 19:357-367.
    • (2009) Curr. Opin. Genet. Dev. , vol.19 , pp. 357-367
    • Tepass, U.1
  • 65
    • 55749101603 scopus 로고    scopus 로고
    • New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity
    • Tinkle C.L., Pasolli H.A., Stokes N., Fuchs E. New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity. Proc. Natl. Acad. Sci. USA 2008, 105:15405-15410.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 15405-15410
    • Tinkle, C.L.1    Pasolli, H.A.2    Stokes, N.3    Fuchs, E.4
  • 68
    • 0033587776 scopus 로고    scopus 로고
    • The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin
    • Vasioukhin V., Degenstein L., Wise B., Fuchs E. The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin. Proc. Natl. Acad. Sci. USA 1999, 96:8551-8556.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8551-8556
    • Vasioukhin, V.1    Degenstein, L.2    Wise, B.3    Fuchs, E.4
  • 69
    • 0034695656 scopus 로고    scopus 로고
    • Directed actin polymerization is the driving force for epithelial cell-cell adhesion
    • Vasioukhin V., Bauer C., Yin M., Fuchs E. Directed actin polymerization is the driving force for epithelial cell-cell adhesion. Cell 2000, 100:209-219.
    • (2000) Cell , vol.100 , pp. 209-219
    • Vasioukhin, V.1    Bauer, C.2    Yin, M.3    Fuchs, E.4
  • 70
    • 0035936807 scopus 로고    scopus 로고
    • Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin
    • Vasioukhin V., Bauer C., Degenstein L., Wise B., Fuchs E. Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin. Cell 2001, 104:605-617.
    • (2001) Cell , vol.104 , pp. 605-617
    • Vasioukhin, V.1    Bauer, C.2    Degenstein, L.3    Wise, B.4    Fuchs, E.5
  • 71
    • 36749070993 scopus 로고    scopus 로고
    • PDZ domains of Par-3 as potential phosphoinositide signaling integrators
    • Wu H., Feng W., Chen J., Chan L.N., Huang S., Zhang M. PDZ domains of Par-3 as potential phosphoinositide signaling integrators. Mol. Cell 2007, 28:886-898.
    • (2007) Mol. Cell , vol.28 , pp. 886-898
    • Wu, H.1    Feng, W.2    Chen, J.3    Chan, L.N.4    Huang, S.5    Zhang, M.6
  • 72
    • 28344433073 scopus 로고    scopus 로고
    • Deconstructing the cadherin-catenin-actin complex
    • Yamada S., Pokutta S., Drees F., Weis W.I., Nelson W.J. Deconstructing the cadherin-catenin-actin complex. Cell 2005, 123:889-901.
    • (2005) Cell , vol.123 , pp. 889-901
    • Yamada, S.1    Pokutta, S.2    Drees, F.3    Weis, W.I.4    Nelson, W.J.5
  • 74
    • 33947095510 scopus 로고    scopus 로고
    • Tight junction proteins in keratinocytes: localization and contribution to barrier function
    • Yuki T., Haratake A., Koishikawa H., Morita K., Miyachi Y., Inoue S. Tight junction proteins in keratinocytes: localization and contribution to barrier function. Exp. Dermatol. 2007, 16:324-330.
    • (2007) Exp. Dermatol. , vol.16 , pp. 324-330
    • Yuki, T.1    Haratake, A.2    Koishikawa, H.3    Morita, K.4    Miyachi, Y.5    Inoue, S.6
  • 75
    • 77954945373 scopus 로고    scopus 로고
    • The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals
    • Zhang N., Bai H., David K.K., Dong J., Zheng Y., Cai J., Giovannini M., Liu P., Anders R.A., Pan D. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev. Cell 2010, 19:27-38.
    • (2010) Dev. Cell , vol.19 , pp. 27-38
    • Zhang, N.1    Bai, H.2    David, K.K.3    Dong, J.4    Zheng, Y.5    Cai, J.6    Giovannini, M.7    Liu, P.8    Anders, R.A.9    Pan, D.10
  • 76
    • 70350502865 scopus 로고    scopus 로고
    • Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
    • Zhou D., Conrad C., Xia F., Park J.S., Payer B., Yin Y., Lauwers G.Y., Thasler W., Lee J.T., Avruch J., et al. Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 2009, 16:425-438.
    • (2009) Cancer Cell , vol.16 , pp. 425-438
    • Zhou, D.1    Conrad, C.2    Xia, F.3    Park, J.S.4    Payer, B.5    Yin, Y.6    Lauwers, G.Y.7    Thasler, W.8    Lee, J.T.9    Avruch, J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.