Probing the efficacy of peptide-based inhibitors against acid- and zinc-promoted oligomerization of amyloid-β peptide via single-oligomer spectroscopy

Biophysical Chemistry

Volumn 160, Issue 1, 2012, Pages 12-19

  Powell, Lyndsey R ^a   Dukes, Kyle D ^a   Lammi, Robin K ^a  

^a WINTHROP UNIVERSITY   (United States)

Author keywords

Acid induced aggregation; Aggregation inhibitor; Amyloid beta peptide; Keywords; Metal induced aggregation; Single molecule spectroscopy; Soluble oligomers

Indexed keywords

AMYLOID BETA PROTEIN; MONOMER; OLIGOMER; PEPTIDE DERIVATIVE; PROTEIN AGGREGATION INHIBITOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; ZINC;

ACIDITY; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; FLUORESCENCE SPECTROSCOPY; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NEUROTOXICITY; OLIGOMERIZATION; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN POLYMERIZATION; PROTEIN STRUCTURE;

ACIDS; AMYLOID BETA-PEPTIDES; HYDROGEN-ION CONCENTRATION; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE; ZINC;

EID: 80455177106     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2011.08.006     Document Type: Article

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