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Volumn 105, Issue 4-5, 1998, Pages 479-488

Cerebrospinal fluid levels of transition metals in patients with Alzheimer's disease

Author keywords

Alzheimer's disease; Cerebrospinal fluid levels; Copper; Iron; Manganese; Serum levels; Transition metals; Zinc

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; COPPER; IRON; MANGANESE; METAL; ZINC;

EID: 14444268040     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020050071     Document Type: Article
Times cited : (148)

References (57)
  • 2
    • 0026041595 scopus 로고
    • Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease
    • Park Dis Dement Sect
    • Basun H, Forssell LG, Wetterberg L, Winblad B (1991) Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease. J Neural Transm [Park Dis Dement Sect] 3: 231-258
    • (1991) J Neural Transm , vol.3 , pp. 231-258
    • Basun, H.1    Forssell, L.G.2    Wetterberg, L.3    Winblad, B.4
  • 3
    • 0029145084 scopus 로고
    • Are reactive oxygen species involved in Alzheimer's disease?
    • Benzi G, Moretti A (1995) Are reactive oxygen species involved in Alzheimer's disease? Neurobiol Aging 16: 661-674
    • (1995) Neurobiol Aging , vol.16 , pp. 661-674
    • Benzi, G.1    Moretti, A.2
  • 4
    • 0019497412 scopus 로고
    • A possible role of zinc in the pathology of dementia
    • Burnet FM (1981) A possible role of zinc in the pathology of dementia. Lancet i: 186-188
    • (1981) Lancet , vol.1 , pp. 186-188
    • Burnet, F.M.1
  • 5
    • 0017180109 scopus 로고
    • Effect of zinc on cells and biomembranes
    • Chvapil M (1976) Effect of zinc on cells and biomembranes. Med Clin North Am 60: 799-812
    • (1976) Med Clin North Am , vol.60 , pp. 799-812
    • Chvapil, M.1
  • 6
    • 0027327899 scopus 로고
    • Ceruloplasmin levels in the human superior temporal gyrus in aging and Alzheimer's disease
    • Connor JR, Tucker P, Johnson M, Snyder B (1993) Ceruloplasmin levels in the human superior temporal gyrus in aging and Alzheimer's disease. Neurosci Lett 159: 88-90
    • (1993) Neurosci Lett , vol.159 , pp. 88-90
    • Connor, J.R.1    Tucker, P.2    Johnson, M.3    Snyder, B.4
  • 7
    • 0025121466 scopus 로고
    • Maladie d'Alzheimer et la theorie du zinc
    • Constantinidis J (1990) Maladie d'Alzheimer et la theorie du zinc. Encephale 16: 231-239
    • (1990) Encephale , vol.16 , pp. 231-239
    • Constantinidis, J.1
  • 8
    • 0025974406 scopus 로고
    • Hypothesis regarding amyloid and zinc in the pathogenesis of Alzheimer disease: Potential for preventive intervention
    • Constantinidis J (1991) Hypothesis regarding amyloid and zinc in the pathogenesis of Alzheimer disease: potential for preventive intervention. Alzheimer Dis Assoc Disord 5: 31-35
    • (1991) Alzheimer Dis Assoc Disord , vol.5 , pp. 31-35
    • Constantinidis, J.1
  • 9
    • 0027669512 scopus 로고
    • Hippocampal tin, aluminum and zinc in Alzheimer's disease
    • Corrigan FM, Reynolds GP, Ward NI (1993) Hippocampal tin, aluminum and zinc in Alzheimer's disease. Biometals 6: 149-154
    • (1993) Biometals , vol.6 , pp. 149-154
    • Corrigan, F.M.1    Reynolds, G.P.2    Ward, N.I.3
  • 10
    • 0030891254 scopus 로고    scopus 로고
    • Zinc and Alzheimer's disease: Is there a direct link?
    • Cuajungco MP, Lees GJ (1997) Zinc and Alzheimer's disease: is there a direct link? Brain Res Rev 23: 219-236
    • (1997) Brain Res Rev , vol.23 , pp. 219-236
    • Cuajungco, M.P.1    Lees, G.J.2
  • 11
    • 0030297178 scopus 로고    scopus 로고
    • Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: Possible relation to oxidative stress
    • Deibel MA, Ehmann WD, Markesbery WR (1996) Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress. J Neurol Sci 143: 137-142
    • (1996) J Neurol Sci , vol.143 , pp. 137-142
    • Deibel, M.A.1    Ehmann, W.D.2    Markesbery, W.R.3
  • 12
    • 0025821265 scopus 로고
    • Alterations in the levels of iron, ferritin, and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia
    • Dexter DT, Carayon A, Javoy-Agid F, Agid Y, Wells FR, Daniel SE, Lees AJ, Jenner P, Marsden CD (1991) Alterations in the levels of iron, ferritin, and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia. Brain 114: 1953-1975
    • (1991) Brain , vol.114 , pp. 1953-1975
    • Dexter, D.T.1    Carayon, A.2    Javoy-Agid, F.3    Agid, Y.4    Wells, F.R.5    Daniel, S.E.6    Lees, A.J.7    Jenner, P.8    Marsden, C.D.9
  • 13
    • 0020408462 scopus 로고
    • Manganese neurotoxicity: A model for free radical mediated neurodegeneration?
    • Donaldson J, McGregor D, LaBella F (1982) Manganese neurotoxicity: a model for free radical mediated neurodegeneration? Can J Physiol Pharmacol 60: 1398-1405
    • (1982) Can J Physiol Pharmacol , vol.60 , pp. 1398-1405
    • Donaldson, J.1    McGregor, D.2    LaBella, F.3
  • 14
    • 0017853370 scopus 로고
    • Free-radical oxidation and antioxidants
    • Dormandy TL (1978) Free-radical oxidation and antioxidants. Lancet i: 647-650
    • (1978) Lancet , vol.1 , pp. 647-650
    • Dormandy, T.L.1
  • 15
    • 0016823810 scopus 로고
    • "Mini-Mental State". A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR (1975) "Mini-Mental State". A practical method for grading the cognitive state of patients for the clinician. J Psychiatry Res 12: 189-198
    • (1975) J Psychiatry Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 16
    • 0031231097 scopus 로고    scopus 로고
    • Molecular genetics of Alzheimer's disease
    • Goate AM (1997) Molecular genetics of Alzheimer's disease. Geriatrics 52 [Suppl 2]: S9-12
    • (1997) Geriatrics , vol.52 , Issue.2 SUPPL.
    • Goate, A.M.1
  • 17
    • 0026573467 scopus 로고
    • Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: A laser microprobe (LAMMA) study
    • Good PF, Perl DP, Bierer LM, Schmeidler J (1992) Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study. Ann Neurol 31: 286-292
    • (1992) Ann Neurol , vol.31 , pp. 286-292
    • Good, P.F.1    Perl, D.P.2    Bierer, L.M.3    Schmeidler, J.4
  • 18
    • 0027193251 scopus 로고
    • Distribution of iron in the basal ganglia and neocortex in postmortem tissue in Parkinson's disease and Alzheimer's disease
    • Griffiths PD, Crossman AR (1993) Distribution of iron in the basal ganglia and neocortex in postmortem tissue in Parkinson's disease and Alzheimer's disease. Dementia 4: 61-65
    • (1993) Dementia , vol.4 , pp. 61-65
    • Griffiths, P.D.1    Crossman, A.R.2
  • 19
    • 0024794826 scopus 로고
    • Serum zinc levels in various mental disorders
    • Gronek I, Kolomaznik M (1989) Serum zinc levels in various mental disorders. Zh Nevropatol Psikhiatr 89: 126-127
    • (1989) Zh Nevropatol Psikhiatr , vol.89 , pp. 126-127
    • Gronek, I.1    Kolomaznik, M.2
  • 24
    • 0020517761 scopus 로고
    • Cerebrospinal fluid trace element content in dementia: Clinical, radiologic, and pathologic correlations
    • Hershey CO, Hershey LA, Varnes A, Vibhakar SD, Lavin P, Strain WH (1983) Cerebrospinal fluid trace element content in dementia: clinical, radiologic, and pathologic correlations. Neurology 33: 1350-1353
    • (1983) Neurology , vol.33 , pp. 1350-1353
    • Hershey, C.O.1    Hershey, L.A.2    Varnes, A.3    Vibhakar, S.D.4    Lavin, P.5    Strain, W.H.6
  • 27
    • 0001823561 scopus 로고    scopus 로고
    • Estrés oxidativo y sistema nervioso central
    • Luquin MR, Jiménez-Jiménez FJ, Martínez-Vila E, Molina-Arjona JA, Bermejo-Pareja F, Coria-Balanzat F (eds) Mecanismos de muerte neuronal y neuroprotección en enfermedades neurológicas
    • Jiménez-Jiménez FJ, de Bustos F, Gasalla T, Ortí-Pareja M (1996) Estrés oxidativo y sistema nervioso central. In: Luquin MR, Jiménez-Jiménez FJ, Martínez-Vila E, Molina-Arjona JA, Bermejo-Pareja F, Coria-Balanzat F (eds) Mecanismos de muerte neuronal y neuroprotección en enfermedades neurológicas. Neurología 11 [Suppl 3]: 13-22
    • (1996) Neurología , vol.11 , Issue.3 SUPPL. , pp. 13-22
    • Jiménez-Jiménez, F.J.1    De Bustos, F.2    Gasalla, T.3    Ortí-Pareja, M.4
  • 28
    • 0030239464 scopus 로고    scopus 로고
    • Brain samples from Alzheimer's patients have elevated levels of loosely bound iron
    • Kala SV, Hasinoff BB, Richardson JS (1996) Brain samples from Alzheimer's patients have elevated levels of loosely bound iron. Int J Neurosci 86: 263-269
    • (1996) Int J Neurosci , vol.86 , pp. 263-269
    • Kala, S.V.1    Hasinoff, B.B.2    Richardson, J.S.3
  • 29
    • 0024598747 scopus 로고
    • Zinc, copper and magnesium concentration in serum and CSF of patients with neurological disorders
    • Kapaki E, Segditsa J, Papageorgiou C (1989) Zinc, copper and magnesium concentration in serum and CSF of patients with neurological disorders. Acta Neurol Scand 79: 373-378
    • (1989) Acta Neurol Scand , vol.79 , pp. 373-378
    • Kapaki, E.1    Segditsa, J.2    Papageorgiou, C.3
  • 30
    • 0002580209 scopus 로고
    • The epidemiology of dementia and Alzheimer's disease
    • Terry RD, Katzman R, Bick KL (eds) Raven Press, New York
    • Katzman R, Kawas C (1994) The epidemiology of dementia and Alzheimer's disease. In: Terry RD, Katzman R, Bick KL (eds) Alzheimer disease. Raven Press, New York, pp 105-122
    • (1994) Alzheimer Disease , pp. 105-122
    • Katzman, R.1    Kawas, C.2
  • 31
    • 0029955035 scopus 로고    scopus 로고
    • Serum levels of the iron binding protein p97 are elevated in Alzheimer's disease
    • Kennard ML, Feldman H, Yamada T, Jefferies WA (1996) Serum levels of the iron binding protein p97 are elevated in Alzheimer's disease. Nat Med 2: 1230-1235
    • (1996) Nat Med , vol.2 , pp. 1230-1235
    • Kennard, M.L.1    Feldman, H.2    Yamada, T.3    Jefferies, W.A.4
  • 32
    • 0028174385 scopus 로고
    • Cerebrospinal fluid ferritin levels of patients with Parkinson's disease, Alzheimer's disease, and multiple system atrophy
    • Park Dis Dement Sect
    • Kuiper MA, Mulder C, van Kamp GJ, Scheltens P, Wolters EC (1994) Cerebrospinal fluid ferritin levels of patients with Parkinson's disease, Alzheimer's disease, and multiple system atrophy. J Neural Transm [Park Dis Dement Sect] 7: 109-114
    • (1994) J Neural Transm , vol.7 , pp. 109-114
    • Kuiper, M.A.1    Mulder, C.2    Van Kamp, G.J.3    Scheltens, P.4    Wolters, E.C.5
  • 33
    • 0030049346 scopus 로고    scopus 로고
    • Impaired peripheral zinc metabolism in patients with senile dementia of probable Alzheimer's type as shown by low plasma concentrations of thymulin
    • Licastro F, Davis LJ, Mocchegiani E, Fabris N (1996) Impaired peripheral zinc metabolism in patients with senile dementia of probable Alzheimer's type as shown by low plasma concentrations of thymulin. Biol Trace Elem Res 51: 55-62
    • (1996) Biol Trace Elem Res , vol.51 , pp. 55-62
    • Licastro, F.1    Davis, L.J.2    Mocchegiani, E.3    Fabris, N.4
  • 38
    • 0023766185 scopus 로고
    • Oxygen toxicity protecting enzymes in Parkinson's disease: Increase of superoxide dismutase-like activity in the substantia nigra and basal nucleus
    • Marttila RJ, Lorentz H, Rinne UK (1988) Oxygen toxicity protecting enzymes in Parkinson's disease: increase of superoxide dismutase-like activity in the substantia nigra and basal nucleus. J Neurol Sci 86: 321-331
    • (1988) J Neurol Sci , vol.86 , pp. 321-331
    • Marttila, R.J.1    Lorentz, H.2    Rinne, U.K.3
  • 39
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • McKahnn G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34: 939-944
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKahnn, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 40
    • 0015057849 scopus 로고
    • Simultaneous direct estimation by atomic absorption spectrophotometry of copper and zinc in serum, urine, and cerebrospinal fluid
    • Meret S, Henkin RI (1971) Simultaneous direct estimation by atomic absorption spectrophotometry of copper and zinc in serum, urine, and cerebrospinal fluid. Clin Chem 17: 369-373
    • (1971) Clin Chem , vol.17 , pp. 369-373
    • Meret, S.1    Henkin, R.I.2
  • 42
    • 0028694082 scopus 로고
    • Non-haem iron histochemistry of the normal and Alzheimer's disease hippocampus
    • Morris CM, Kerwin JM, Edwardson JA (1994) Non-haem iron histochemistry of the normal and Alzheimer's disease hippocampus. Neurodegeneration 3: 267-275
    • (1994) Neurodegeneration , vol.3 , pp. 267-275
    • Morris, C.M.1    Kerwin, J.M.2    Edwardson, J.A.3
  • 43
    • 0029935396 scopus 로고    scopus 로고
    • The amyloid precursor protein of Alzheimer's disease in the reduction of copper (II) to copper (I)
    • Multhaup G, Schlicksupp A, Hesse L, Beher L, Ruppert T, Masters CL, Beyreuther K (1996) The amyloid precursor protein of Alzheimer's disease in the reduction of copper (II) to copper (I). Science 271: 1406-1409
    • (1996) Science , vol.271 , pp. 1406-1409
    • Multhaup, G.1    Schlicksupp, A.2    Hesse, L.3    Beher, L.4    Ruppert, T.5    Masters, C.L.6    Beyreuther, K.7
  • 44
    • 0014528748 scopus 로고
    • A new method for serum iron and total iron-binding capacity by atomic absorption spectrophotometry
    • Olson AD, Hamlin WB (1969) A new method for serum iron and total iron-binding capacity by atomic absorption spectrophotometry. Clin Chem 15: 438-444
    • (1969) Clin Chem , vol.15 , pp. 438-444
    • Olson, A.D.1    Hamlin, W.B.2
  • 45
    • 51249175720 scopus 로고
    • Trace elements in the human central nervous system studied with neutron activation analysis
    • Plantin LO, Lying-Tunell U, Kristensson K (1987) Trace elements in the human central nervous system studied with neutron activation analysis. Biol Trace Element Res 13: 69-75
    • (1987) Biol Trace Element Res , vol.13 , pp. 69-75
    • Plantin, L.O.1    Lying-Tunell, U.2    Kristensson, K.3
  • 46
    • 0024321178 scopus 로고
    • A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra
    • Saggu H, Cooksey J, Dexter D, Wells FR, Lees A, Jenner P, Marsden CD (1989) A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra. J Neurochem 53: 692-697
    • (1989) J Neurochem , vol.53 , pp. 692-697
    • Saggu, H.1    Cooksey, J.2    Dexter, D.3    Wells, F.R.4    Lees, A.5    Jenner, P.6    Marsden, C.D.7
  • 48
    • 0028145566 scopus 로고
    • Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography
    • Saura J, Luque JM, Cesura AM, Da Prada M, Chan-Palay V, Huber G, Loffler J, Richards JG (1994) Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. Neuroscience 62: 15-30
    • (1994) Neuroscience , vol.62 , pp. 15-30
    • Saura, J.1    Luque, J.M.2    Cesura, A.M.3    Da Prada, M.4    Chan-Palay, V.5    Huber, G.6    Loffler, J.7    Richards, J.G.8
  • 50
    • 0020692477 scopus 로고
    • Accuracy of clinical diagnosis in primary degenerative dementia: Correlation with neuropathological findings
    • Sulkava R, Haltia M, Paetau A, Wikstrom J, Palo J (1983) Accuracy of clinical diagnosis in primary degenerative dementia: correlation with neuropathological findings. J Neurol Neurosurg Psychiatry 46: 9-13
    • (1983) J Neurol Neurosurg Psychiatry , vol.46 , pp. 9-13
    • Sulkava, R.1    Haltia, M.2    Paetau, A.3    Wikstrom, J.4    Palo, J.5
  • 51
    • 0028807286 scopus 로고
    • Serum zinc, senile plaques, and neurofibrillary tangles: Findings from the Nun Study
    • Tully CL, Snowdon DA, Markesbery WR (1995) Serum zinc, senile plaques, and neurofibrillary tangles: findings from the Nun Study. NeuroReport 6: 2105-2108
    • (1995) NeuroReport , vol.6 , pp. 2105-2108
    • Tully, C.L.1    Snowdon, D.A.2    Markesbery, W.R.3
  • 54
    • 0023571213 scopus 로고
    • Neutron activation analysis for identifying elemental status in Alzheimer's disease
    • Ward NI, Mason JA (1987) Neutron activation analysis for identifying elemental status in Alzheimer's disease. J Radioanal Nucl Chem 113: 293-298
    • (1987) J Radioanal Nucl Chem , vol.113 , pp. 293-298
    • Ward, N.I.1    Mason, J.A.2
  • 55
    • 0025153318 scopus 로고
    • Trace element imbalances in isolated subcellular fractions of Alzheimer's disease brains
    • Wenstrup D, Ehmann WD, Markesbery WR (1990) Trace element imbalances in isolated subcellular fractions of Alzheimer's disease brains. Brain Res 533: 125-131
    • (1990) Brain Res , vol.533 , pp. 125-131
    • Wenstrup, D.1    Ehmann, W.D.2    Markesbery, W.R.3
  • 56
    • 0023866742 scopus 로고
    • Iron in the brain: Implications for Parkinson's and Alzheimer's disease
    • Youdim MBH (1988) Iron in the brain: implications for Parkinson's and Alzheimer's disease. Mt Sinai J Med 55: 97-101
    • (1988) Mt Sinai J Med , vol.55 , pp. 97-101
    • Youdim, M.B.H.1


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