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Volumn 8, Issue 4, 2011, Pages 251-257

Alterations in regulatory T-cells: Rediscovered pathways in immunotoxicology

Author keywords

Allergy; Autoimmunity; Immunosuppression; Regulatory T cells

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALLERGEN; AROMATIC HYDROCARBON RECEPTOR; INTERLEUKIN 10; SUPPRESSOR FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; XENOBIOTIC AGENT;

EID: 80455150597     PISSN: 1547691X     EISSN: None     Source Type: Journal    
DOI: 10.3109/1547691X.2011.598885     Document Type: Review
Times cited : (23)

References (67)
  • 1
    • 4644275197 scopus 로고    scopus 로고
    • Regulatory T cells: Peace keepers in the gut
    • Allez, M. and Mayer, L. 2004. Regulatory T cells: Peace keepers in the gut. Inflamm. Bowel Dis. 10:666-676.
    • (2004) Inflamm. Bowel Dis. , vol.10 , pp. 666-676
    • Allez, M.1    Mayer, L.2
  • 2
    • 0035892882 scopus 로고    scopus 로고
    • Tolerance to nickel: Oral nickel administration induces a high frequency of anergic T-cells with persistent suppressor activity
    • Artik, S., Haarhuis, K., Wu, X., Begerow, J. and Gleichmann, E. 2001. Tolerance to nickel: Oral nickel administration induces a high frequency of anergic T-cells with persistent suppressor activity. J. Immunol. 167:6794-6803.
    • (2001) J. Immunol. , vol.167 , pp. 6794-6803
    • Artik, S.1    Haarhuis, K.2    Wu, X.3    Begerow, J.4    Gleichmann, E.5
  • 5
    • 0026603775 scopus 로고
    • Revisiting and revising suppressor T-cells
    • Bloom, B. R., Salgame, P. and Diamond, B. 1992. Revisiting and revising suppressor T-cells. Immunol. Today 13:131-136.
    • (1992) Immunol. Today , vol.13 , pp. 131-136
    • Bloom, B.R.1    Salgame, P.2    Diamond, B.3
  • 8
    • 1642308173 scopus 로고    scopus 로고
    • Differential response of murine CD4+CD25+ and CD4+CD25- T-cells to dexamethasone-induced cell death
    • Chen, X., Murakami, T., Oppenheim, J. J. and Howard, O. M. 2004. Differential response of murine CD4+CD25+ and CD4+CD25- T-cells to dexamethasone-induced cell death. Eur. J. Immunol. 34:859-869.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 859-869
    • Chen, X.1    Murakami, T.2    Oppenheim, J.J.3    Howard, O.M.4
  • 9
    • 35548950221 scopus 로고    scopus 로고
    • Regulatory-T-cell inhibition versus depletion: The right choice in cancer immunotherapy
    • Colombo, M. P. and Piconese, S. 2007. Regulatory-T-cell inhibition versus depletion: The right choice in cancer immunotherapy. Nat. Rev. 7:880-887.
    • (2007) Nat. Rev. , vol.7 , pp. 880-887
    • Colombo, M.P.1    Piconese, S.2
  • 11
    • 0037369579 scopus 로고    scopus 로고
    • Regulatory CD8+ T-cells control neonatal tolerance to a Th2-mediated autoimmunity
    • Field, A. C., Caccavelli, L., Bloch, M. F. and Bellon, B. 2003. Regulatory CD8+ T-cells control neonatal tolerance to a Th2-mediated autoimmunity. J. Immunol. 170:2508-2515.
    • (2003) J. Immunol. , vol.170 , pp. 2508-2515
    • Field, A.C.1    Caccavelli, L.2    Bloch, M.F.3    Bellon, B.4
  • 15
    • 77956934564 scopus 로고    scopus 로고
    • Manipulation of regulatory T-cell function by immunomodulators: A boon or a curse?
    • Fort, M. M. and Narayanan, P. K. 2010. Manipulation of regulatory T-cell function by immunomodulators: A boon or a curse? Toxicol. Sci. 117:253-262.
    • (2010) Toxicol. Sci. , vol.117 , pp. 253-262
    • Fort, M.M.1    Narayanan, P.K.2
  • 17
    • 41149083510 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation of alloreactive CD8+ T-cells toward a regulatory T-cell phenotype by a mechanism that is dependent on aryl hydrocarbon receptor in CD4+ T-cells
    • Funatake, C. J., Marshall, N. B. and Kerkvliet, N. I. 2008. 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation of alloreactive CD8+ T-cells toward a regulatory T-cell phenotype by a mechanism that is dependent on aryl hydrocarbon receptor in CD4+ T-cells. J. Immunotoxicol. 5:81-91.
    • (2008) J. Immunotoxicol. , vol.5 , pp. 81-91
    • Funatake, C.J.1    Marshall, N.B.2    Kerkvliet, N.I.3
  • 18
    • 25444526629 scopus 로고    scopus 로고
    • Cutting edge: Activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T-cells
    • Funatake, C. J., Marshall, N. B., Steppan, L. B., Mourich, D. V. and Kerkvliet, N. I. 2005. Cutting edge: Activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T-cells J. Immunol. 175:4184-4188.
    • (2005) J. Immunol. , vol.175 , pp. 4184-4188
    • Funatake, C.J.1    Marshall, N.B.2    Steppan, L.B.3    Mourich, D.V.4    Kerkvliet, N.I.5
  • 19
    • 0015172562 scopus 로고
    • Infectious immunological tolerance
    • Gershon, R. K. and Kondo, K. 1971. Infectious immunological tolerance. Immunology. 21:903-914.
    • (1971) Immunology. , vol.21 , pp. 903-914
    • Gershon, R.K.1    Kondo, K.2
  • 20
    • 51649101135 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T-cells
    • Hauben, E., Gregori, S., Draghici, E., Migliavacca, B., Olivieri, S., Woisetschläger, M. and Roncarolo, M. G. 2008. Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T-cells. Blood 112:1214-1222.
    • (2008) Blood , vol.112 , pp. 1214-1222
    • Hauben, E.1    Gregori, S.2    Draghici, E.3    Migliavacca, B.4    Olivieri, S.5    Woisetschläger, M.6    Roncarolo, M.G.7
  • 21
    • 9144219649 scopus 로고    scopus 로고
    • Cutting edge: TGF-ǎ signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T-cells
    • Huber, S., Schramm, C., Lehr, H. A., Mann, A., Schmitt, S., Becker, C., Protschka, M., Galle, P. R., Neurath, M. F. and Blessing, M. 2004. Cutting edge: TGF-ǎ signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T-cells. J. Immunol. 173:6526-6531.
    • (2004) J. Immunol. , vol.173 , pp. 6526-6531
    • Huber, S.1    Schramm, C.2    Lehr, H.A.3    Mann, A.4    Schmitt, S.5    Becker, C.6    Protschka, M.7    Galle, P.R.8    Neurath, M.F.9    Blessing, M.10
  • 22
    • 23044445625 scopus 로고    scopus 로고
    • Cyclophosphamide decreases the number, percentage and the function of CD25+ CD4+ regulatory T-cells, which suppress induction of contact hypersensitivity
    • Ikezawa, Y., Nakazawa, M., Tamura, C., Takahashi, K., Minami, M. and Ikezawa, Z. 2005. Cyclophosphamide decreases the number, percentage and the function of CD25+ CD4+ regulatory T-cells, which suppress induction of contact hypersensitivity. J. Dermatol. Sci. 39:105-112.
    • (2005) J. Dermatol. Sci. , vol.39 , pp. 105-112
    • Ikezawa, Y.1    Nakazawa, M.2    Tamura, C.3    Takahashi, K.4    Minami, M.5    Ikezawa, Z.6
  • 23
    • 0346996879 scopus 로고    scopus 로고
    • The regulatory T-cell family: Distinct subsets and their interrelations
    • Jonuleit, H. and Schmitt, E. 2003. The regulatory T-cell family: Distinct subsets and their interrelations. J. Immunol. 171:6323-6327.
    • (2003) J. Immunol. , vol.171 , pp. 6323-6327
    • Jonuleit, H.1    Schmitt, E.2
  • 25
    • 0036147662 scopus 로고    scopus 로고
    • Recent advances in understanding the mechanisms of TCDD immunotoxicity
    • Kerkvliet, N. I. 2002. Recent advances in understanding the mechanisms of TCDD immunotoxicity. Int. Immunopharmacol. 2:277-291.
    • (2002) Int. Immunopharmacol. , vol.2 , pp. 277-291
    • Kerkvliet, N.I.1
  • 26
    • 74549198640 scopus 로고    scopus 로고
    • Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases FoxP3+ T-cells in pancreatic lymph nodes
    • Kerkvliet, N. I., Steppan, L. B., Vorachek, W., Oda, S., Farrer, D., Wong, C. P., Pham, D. and Mourich, D. V. 2009. Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases FoxP3+ T-cells in pancreatic lymph nodes. Immunotherapy. 1:539-547.
    • (2009) Immunotherapy , vol.1 , pp. 539-547
    • Kerkvliet, N.I.1    Steppan, L.B.2    Vorachek, W.3    Oda, S.4    Farrer, D.5    Wong, C.P.6    Pham, D.7    Mourich, D.V.8
  • 27
    • 47749107262 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of TH17 cells
    • Kimura, A., Naka, T., Nohara, K., Fujii-Kuriyama, Y. and Kishimoto, T. 2008. Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of TH17 cells. Proc. Natl. Acad. Sci. U.S.A. 105:9721-9726.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 9721-9726
    • Kimura, A.1    Naka, T.2    Nohara, K.3    Fujii-Kuriyama, Y.4    Kishimoto, T.5
  • 28
    • 65749103365 scopus 로고    scopus 로고
    • The transcription factor T-bet controls regulatory T-cell homeostasis and function during type 1 inflammation
    • Koch, M. A., Tucker-Heard, G., Perdue, N. R., Killebrew, J. R., Urdahl, K. B. and Campbell, D. J. 2009. The transcription factor T-bet controls regulatory T-cell homeostasis and function during type 1 inflammation. Nat. Immunol. 10:595-602.
    • (2009) Nat. Immunol. , vol.10 , pp. 595-602
    • Koch, M.A.1    Tucker-Heard, G.2    Perdue, N.R.3    Killebrew, J.R.4    Urdahl, K.B.5    Campbell, D.J.6
  • 30
    • 0028365787 scopus 로고
    • Role of RT6+ T-lymphocytes in mercury-induced renal autoimmunity: Experimental manipulations of "susceptible" and "resistant" rats
    • Kosuda, L. L., Hosseinzadeh, H., Greiner, D. L. and Bigazzi, P. E. 1994. Role of RT6+ T-lymphocytes in mercury-induced renal autoimmunity: Experimental manipulations of "susceptible" and "resistant" rats. J. Toxicol. Environ. Health. 42:303-321.
    • (1994) J. Toxicol. Environ. Health. , vol.42 , pp. 303-321
    • Kosuda, L.L.1    Hosseinzadeh, H.2    Greiner, D.L.3    Bigazzi, P.E.4
  • 31
    • 33846798312 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes: Their shared and divergent immunological behaviors in the small and large intestine
    • Kunisawa, J., Takahashi, I. and Kiyono, H. 2007. Intraepithelial lymphocytes: Their shared and divergent immunological behaviors in the small and large intestine. Immunol. Rev. 215:136-153.
    • (2007) Immunol. Rev. , vol.215 , pp. 136-153
    • Kunisawa, J.1    Takahashi, I.2    Kiyono, H.3
  • 32
    • 35448997248 scopus 로고    scopus 로고
    • Regulatory T-cells in the prevention of mucosal inflammatory diseases: Patrolling the border
    • Lan, R. Y., Mackay, I. R. and Gershwin, M. E. 2007. Regulatory T-cells in the prevention of mucosal inflammatory diseases: Patrolling the border. J. Autoimmun. 29:272-280.
    • (2007) J. Autoimmun. , vol.29 , pp. 272-280
    • Lan, R.Y.1    MacKay, I.R.2    Gershwin, M.E.3
  • 33
    • 1642513838 scopus 로고    scopus 로고
    • Drug-induced autoantibody formation in mice: Triggering by primed CD4+CD25- T-cells, prevention by primed CD4+CD25+ T-cells
    • Layland, L. E., Wulferink, M., Dierkes, S. and Gleichmann, E. 2004. Drug-induced autoantibody formation in mice: Triggering by primed CD4+CD25- T-cells, prevention by primed CD4+CD25+ T-cells. Eur. J. Immunol. 34:36-46.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 36-46
    • Layland, L.E.1    Wulferink, M.2    Dierkes, S.3    Gleichmann, E.4
  • 34
    • 77950349016 scopus 로고    scopus 로고
    • TH17 and regulatory T-cells in mediating and restraining inflammation
    • Littman, D. R. and Rudensky, A. Y. 2010. TH17 and regulatory T-cells in mediating and restraining inflammation. Cell 140:845-858.
    • (2010) Cell , vol.140 , pp. 845-858
    • Littman, D.R.1    Rudensky, A.Y.2
  • 36
    • 0015088842 scopus 로고
    • Tolerance of dinitrochlorobenzene, a contact sensitizer, in man
    • Lowney, E. D. 1971. Tolerance of dinitrochlorobenzene, a contact sensitizer, in man. J. Allergy Clin. Immunol. 48:28-35.
    • (1971) J. Allergy Clin. Immunol. , vol.48 , pp. 28-35
    • Lowney, E.D.1
  • 37
    • 53149148154 scopus 로고    scopus 로고
    • Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T-cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo-p- dioxin
    • Marshall, N. B., Vorachek, W. R., Steppan, L. B., Mourich, D. V. and Kerkvliet, N. I. 2008. Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T-cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Immunol. 181:2382-2391.
    • (2008) J. Immunol. , vol.181 , pp. 2382-2391
    • Marshall, N.B.1    Vorachek, W.R.2    Steppan, L.B.3    Mourich, D.V.4    Kerkvliet, N.I.5
  • 38
    • 1642457336 scopus 로고    scopus 로고
    • Tolerance induced by low dose D-penicillamine in the Brown Norway rat model of druginduced autoimmunity is immune-mediated
    • Masson, M. J. and Uetrecht, J. P. 2004. Tolerance induced by low dose D-penicillamine in the Brown Norway rat model of druginduced autoimmunity is immune-mediated. Chem. Res. Toxicol. 17:82-94.
    • (2004) Chem. Res. Toxicol. , vol.17 , pp. 82-94
    • Masson, M.J.1    Uetrecht, J.P.2
  • 39
    • 0025743495 scopus 로고
    • Immunoregulation of mercuric chloride-induced autoimmunity in Brown Norway rats: A role for CD8+ T-cells revealed by in vivo depletion studies
    • Mathieson, P. W., Stapleton, K. J., Oliveira, D. B. and Lockwood, C. M. 1991. Immunoregulation of mercuric chloride-induced autoimmunity in Brown Norway rats: A role for CD8+ T-cells revealed by in vivo depletion studies. Eur. J. Immunol. 21:2105-2109.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2105-2109
    • Mathieson, P.W.1    Stapleton, K.J.2    Oliveira, D.B.3    Lockwood, C.M.4
  • 40
    • 0038316325 scopus 로고    scopus 로고
    • Anatomical basis of tolerance and immunity to intestinal antigens
    • Mowat, A. M. 2003. Anatomical basis of tolerance and immunity to intestinal antigens. Nat. Rev. Immunol. 3:331-341.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 331-341
    • Mowat, A.M.1
  • 42
    • 0023860697 scopus 로고
    • Autoreactive T-cells in mercury-induced autoimmunity. Ability to induce the autoimmune disease
    • Pelletier, L., Pasquier, R., Rossert, J., Vial, M. C., Mandet, C. and Druet, P. 1988. Autoreactive T-cells in mercury-induced autoimmunity. Ability to induce the autoimmune disease. J. Immunol. 140:750-754.
    • (1988) J. Immunol. , vol.140 , pp. 750-754
    • Pelletier, L.1    Pasquier, R.2    Rossert, J.3    Vial, M.C.4    Mandet, C.5    Druet, P.6
  • 43
    • 0025159240 scopus 로고
    • Role of CD8+ T-cells in mercury-induced autoimmunity or immunosuppression in the rat
    • Pelletier, L., Rossert, J., Pasquier, R., Vial, M. C. and Druet, P. 1990. Role of CD8+ T-cells in mercury-induced autoimmunity or immunosuppression in the rat. Scand. J. Immunol. 31:65-74.
    • (1990) Scand. J. Immunol. , vol.31 , pp. 65-74
    • Pelletier, L.1    Rossert, J.2    Pasquier, R.3    Vial, M.C.4    Druet, P.5
  • 44
    • 77957054466 scopus 로고    scopus 로고
    • The mammalian target of rapamycin: Linking T-cell differentiation, function, and metabolism
    • Powell, J. D. and Delgoffe, G. M. 2010. The mammalian target of rapamycin: Linking T-cell differentiation, function, and metabolism. Immunity 33:301-311.
    • (2010) Immunity , vol.33 , pp. 301-311
    • Powell, J.D.1    Delgoffe, G.M.2
  • 46
    • 3142680192 scopus 로고    scopus 로고
    • Oral tolerance to nickel requires CD4+ invariant NKT-cells for the infectious spread of tolerance and the induction of specific regulatory T-cells
    • Roelofs-Haarhuis, K., Wu, X. and Gleichmann, E. 2004. Oral tolerance to nickel requires CD4+ invariant NKT-cells for the infectious spread of tolerance and the induction of specific regulatory T-cells. J. Immunol. 173:1043-1050.
    • (2004) J. Immunol. , vol.173 , pp. 1043-1050
    • Roelofs-Haarhuis, K.1    Wu, X.2    Gleichmann, E.3
  • 47
    • 0033738329 scopus 로고    scopus 로고
    • The role of different subsets of T-regulatory cells in controlling autoimmunity
    • Roncarolo, M. G. and Levings, M. K. 2000. The role of different subsets of T-regulatory cells in controlling autoimmunity. Curr. Opin. Immunol. 12:676-683.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 676-683
    • Roncarolo, M.G.1    Levings, M.K.2
  • 48
    • 33746383248 scopus 로고    scopus 로고
    • Regulatory T-cells in virus infections
    • Rouse, B. T., Sarangi, P. P. and Suvas, S. 2006. Regulatory T-cells in virus infections. Immunol. Rev. 212:272-286.
    • (2006) Immunol. Rev. , vol.212 , pp. 272-286
    • Rouse, B.T.1    Sarangi, P.P.2    Suvas, S.3
  • 50
    • 34547749066 scopus 로고    scopus 로고
    • Emerging challenges in regulatory T-cell function and biology
    • Sakaguchi, S. and Powrie, F. 2007. Emerging challenges in regulatory T-cell function and biology. Science 317:627-629.
    • (2007) Science , vol.317 , pp. 627-629
    • Sakaguchi, S.1    Powrie, F.2
  • 51
    • 77949734784 scopus 로고    scopus 로고
    • Oligosaccharideinduced whey-specific CD25+ regulatory T-cells are involved in the suppression of cow milk allergy in mice
    • Schouten, B., van Esch, B. C., Hofman, G. A., Boon, L., Knippels, L. M., Willemsen, L. E. and Garssen, J. 2010. Oligosaccharideinduced whey-specific CD25+ regulatory T-cells are involved in the suppression of cow milk allergy in mice. J. Nutr. 140:835-841.
    • (2010) J. Nutr. , vol.140 , pp. 835-841
    • Schouten, B.1    Van Esch, B.C.2    Hofman, G.A.3    Boon, L.4    Knippels, L.M.5    Willemsen, L.E.6    Garssen, J.7
  • 52
    • 6344277103 scopus 로고    scopus 로고
    • D-Penicillamineinduced autoimmunity in the Brown Norway rat: Role for both T- and non-T splenocytes in adoptive transfer of tolerance
    • Séguin, B., Masson, M. J. and Uetrecht, J. 2004. D-Penicillamineinduced autoimmunity in the Brown Norway rat: Role for both T- and non-T splenocytes in adoptive transfer of tolerance. Chem. Res. Toxicol. 17:1299-1302.
    • (2004) Chem. Res. Toxicol. , vol.17 , pp. 1299-1302
    • Séguin, B.1    Masson, M.J.2    Uetrecht, J.3
  • 53
    • 0141624936 scopus 로고    scopus 로고
    • Characterization of a potential animal model of an idiosyncratic drug reaction: Nevirapine-induced skin rash in the rat
    • Shenton, J. M., Teranishi, M., Abu-Asab, M. S., Yager, J. A. and Uetrecht, J. P. 2003. Characterization of a potential animal model of an idiosyncratic drug reaction: Nevirapine-induced skin rash in the rat. Chem. Res. Toxicol. 16:1078-1089.
    • (2003) Chem. Res. Toxicol. , vol.16 , pp. 1078-1089
    • Shenton, J.M.1    Teranishi, M.2    Abu-Asab, M.S.3    Yager, J.A.4    Uetrecht, J.P.5
  • 55
    • 45549107134 scopus 로고    scopus 로고
    • Revival of CD8+ Treg-mediated suppression
    • Smith, T. R. and Kumar, V. 2008. Revival of CD8+ Treg-mediated suppression. Trends Immunol. 29:337-342.
    • (2008) Trends Immunol. , vol.29 , pp. 337-342
    • Smith, T.R.1    Kumar, V.2
  • 57
    • 66549106623 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor: A perspective on potential roles in the immune system
    • Stevens, E. A., Mezrich, J. D. and Bradfield, C. A. 2009. The aryl hydrocarbon receptor: A perspective on potential roles in the immune system. Immunology 127:299-311.
    • (2009) Immunology , vol.127 , pp. 299-311
    • Stevens, E.A.1    Mezrich, J.D.2    Bradfield, C.A.3
  • 58
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs TH1 lineage commitment
    • Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G. and Glimcher, L. H. 2000. A novel transcription factor, T-bet, directs TH1 lineage commitment. Cell 100:655-669.
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3    Zhang, X.4    Fathman, C.G.5    Glimcher, L.H.6
  • 59
    • 0032802350 scopus 로고    scopus 로고
    • Low-dose mercuric chloride induces resistance in Brown Norway rats to further mercuric chloride by up-regulation of interferon-ã
    • Szeto, C., Gillespie, K. M. and Mathieson, P. W. 1999. Low-dose mercuric chloride induces resistance in Brown Norway rats to further mercuric chloride by up-regulation of interferon-ã. Scand. J. Immunol. 50:195-201.
    • (1999) Scand. J. Immunol. , vol.50 , pp. 195-201
    • Szeto, C.1    Gillespie, K.M.2    Mathieson, P.W.3
  • 60
    • 0035399985 scopus 로고    scopus 로고
    • Generation of anergic and potentially immunoregulatory CD25+CD4+ T-cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • Thorstenson, K. M. and Khoruts, A. 2001. Generation of anergic and potentially immunoregulatory CD25+CD4+ T-cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J. Immunol. 167:188-195.
    • (2001) J. Immunol. , vol.167 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 61
    • 34047232649 scopus 로고    scopus 로고
    • CD4+CD25+ T-cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization
    • van Wijk, F., Wehrens, E. J., Nierkens, S., Boon, L., Kasran, A., Pieters, R. and Knippels, L. M. 2007. CD4+CD25+ T-cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization. Clin. Exp. Allergy 37:572-581.
    • (2007) Clin. Exp. Allergy , vol.37 , pp. 572-581
    • Van Wijk, F.1    Wehrens, E.J.2    Nierkens, S.3    Boon, L.4    Kasran, A.5    Pieters, R.6    Knippels, L.M.7
  • 62
    • 60549095448 scopus 로고    scopus 로고
    • Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of TH17 T-cells
    • Veldhoen, M., Hirota, K., Christensen, J., O'Garra, A. and Stockinger, B. 2009a. Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of TH17 T-cells. J. Exp. Med. 206:43-49.
    • (2009) J. Exp. Med. , vol.206 , pp. 43-49
    • Veldhoen, M.1    Hirota, K.2    Christensen, J.3    O'Garra, A.4    Stockinger, B.5
  • 63
  • 64
    • 0035282330 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules
    • Vorderstrasse, B. A. and Kerkvliet, N. I. 2001. 2,3,7,8- Tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules. Toxicol. Appl. Pharmacol. 171:117-125.
    • (2001) Toxicol. Appl. Pharmacol. , vol.171 , pp. 117-125
    • Vorderstrasse, B.A.1    Kerkvliet, N.I.2
  • 66
    • 33746328653 scopus 로고    scopus 로고
    • Dendritic cells expand antigen-specific FoxP3+CD25+CD4+ regulatory T-cells including suppressors of alloreactivity
    • Yamazaki, S., Inaba, K., Tarbell, K. V. and Steinman, R. M. 2006. Dendritic cells expand antigen-specific FoxP3+CD25+CD4+ regulatory T-cells including suppressors of alloreactivity. Immunol. Rev. 212:314-329.
    • (2006) Immunol. Rev. , vol.212 , pp. 314-329
    • Yamazaki, S.1    Inaba, K.2    Tarbell, K.V.3    Steinman, R.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.