Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases Foxp3 + T cells in pancreatic lymph nodes

Immunotherapy

Volumn 1, Issue 4, 2009, Pages 539-547

  Kerkvliet, Nancy I ^a,b   Steppan, Linda B ^a,b   Vorachek, William ^a,b   Oda, Shannon ^a   Farrer, David ^a,b   Wong, Carmen P ^c   Pham, Duy ^a   Mourich, Dan V ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b OREGON DEPARTMENT OF HUMAN SERVICES   (United States)

^c Deparment of Nutrition and Exercise Sciences   (United States)

Author keywords

2,3,7,8 tetrachlorodibenzo p dioxin; AHR; Aryl hydrocarbon receptor; NOD mice; Regulatory T cell; TCDD; Type 1 diabetes

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CD4+ CD25+ T LYMPHOCYTE; FEMALE; GENE EXPRESSION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; LOADING DRUG DOSE; LYMPH NODE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD4; CELL PROLIFERATION; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LIGANDS; LYMPH NODES; MICE; MICE, INBRED NOD; PANCREAS; RECEPTORS, ARYL HYDROCARBON; T-LYMPHOCYTES, REGULATORY; TETRACHLORODIBENZODIOXIN;

EID: 74549198640     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/IMT.09.24     Document Type: Article

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