-
1
-
-
0023253372
-
Guam ALS/Parkinsonism-dementia: A long-latency neurotoxic disorder caused by 'slow toxin(s)' in food
-
Spencer, P.S. Guam ALS/Parkinsonism-dementia: A long-latency neurotoxic disorder caused by 'slow toxin(s)' in food? Can. J. Neurol. Sci. 1987, 14, 347-357.
-
(1987)
Can. J. Neurol. Sci
, vol.14
, pp. 347-357
-
-
Spencer, P.S.1
-
2
-
-
0026160504
-
Slow toxins, biologic markers, and long-latency neurodegenerative disease in the western Pacific region
-
Spencer, P.S.; Kisby, G.E.; Ludolph, A.C. Slow toxins, biologic markers, and long-latency neurodegenerative disease in the western Pacific region. Neurology 1991, 41, 62-66.
-
(1991)
Neurology
, vol.41
, pp. 62-66
-
-
Spencer, P.S.1
Kisby, G.E.2
Ludolph, A.C.3
-
3
-
-
79959535096
-
The ALS/PDC syndrome of Guam: Potential biomarkers for anenigmatic disorder
-
In press
-
McGeer, P.L.; Steele, J.C. The ALS/PDC syndrome of Guam: Potential biomarkers for anenigmatic disorder. Prog. Neurobiol. 2011, In press.
-
(2011)
Prog. Neurobiol
-
-
McGeer, P.L.1
Steele, J.C.2
-
4
-
-
33646254380
-
Characterization of tau pathologies in gray and white matter of Guam parkinsonism-dementia complex
-
Winton, M.J.; Joyce, S.; Zhukareva, V.; Practico, D.; Perl, D.P.; Galasko, D.; Craig, U.; Trojanowski, J.Q.; Lee, V.M. Characterization of tau pathologies in gray and white matter of Guam parkinsonism-dementia complex. Acta Neuropathol. 2006, 111, 401-412.
-
(2006)
Acta Neuropathol
, vol.111
, pp. 401-412
-
-
Winton, M.J.1
Joyce, S.2
Zhukareva, V.3
Practico, D.4
Perl, D.P.5
Galasko, D.6
Craig, U.7
Trojanowski, J.Q.8
Lee, V.M.9
-
5
-
-
3242742880
-
Incidence of amyotrophic lateral sclerosis and of the parkinsonism-dementia complex of Guam, 1950-1989
-
Waring, S.C.; Esteban-Santillan, C.; Reed, D.M.; Craig, U.K.; Labarthe, D.R.; Petersen, R.C.; Kurland, L.T. Incidence of amyotrophic lateral sclerosis and of the parkinsonism-dementia complex of Guam, 1950-1989. Neuroepidemiology 2004, 23, 192-200.
-
(2004)
Neuroepidemiology
, vol.23
, pp. 192-200
-
-
Waring, S.C.1
Esteban-Santillan, C.2
Reed, D.M.3
Craig, U.K.4
Labarthe, D.R.5
Petersen, R.C.6
Kurland, L.T.7
-
6
-
-
26444551246
-
Atypical parkinsonism of Japan: Amyotrophic lateral sclerosis-parkinsonism-dementia complex of the Kii peninsula of Japan (Muro disease): An update
-
Kuzuhara, S.; Kokubo, Y. Atypical parkinsonism of Japan: Amyotrophic lateral sclerosis-parkinsonism-dementia complex of the Kii peninsula of Japan (Muro disease): An update. Mov. Disord. 2005, 20, S108-S113.
-
(2005)
Mov. Disord
, vol.20
-
-
Kuzuhara, S.1
Kokubo, Y.2
-
7
-
-
34249901269
-
Similar topographical distribution of neurofibrillary tangles in amyotrophic lateral sclerosis and parkinsonism-dementia complex in people living in the Kii peninsula of Japan suggests a single tauopathy
-
Mimuro, M.; Kokubo, Y.; Kuzuhara, S. Similar topographical distribution of neurofibrillary tangles in amyotrophic lateral sclerosis and parkinsonism-dementia complex in people living in the Kii peninsula of Japan suggests a single tauopathy. Acta Neuropathol. 2007, 113, 653-658.
-
(2007)
Acta Neuropathol
, vol.113
, pp. 653-658
-
-
Mimuro, M.1
Kokubo, Y.2
Kuzuhara, S.3
-
8
-
-
0020078435
-
Amyotrophic lateral sclerosis and parkinsonian syndromes in high incidence among the Auyu and Jakai people of West New Guinea
-
Gajdusek, D.C.; Salazar, A.M. Amyotrophic lateral sclerosis and parkinsonian syndromes in high incidence among the Auyu and Jakai people of West New Guinea. Neurology 1982, 32, 107-126.
-
(1982)
Neurology
, vol.32
, pp. 107-126
-
-
Gajdusek, D.C.1
Salazar, A.M.2
-
9
-
-
26444509015
-
On the decline and etiology of high incidence motor system disease in West Papua (southwest New Guinea)
-
Spencer, P.S.; Palmer, V.S.; Ludolph, A.C. On the decline and etiology of high incidence motor system disease in West Papua (southwest New Guinea). Mov. Disord. 2005, 20, 119-126.
-
(2005)
Mov. Disord
, vol.20
, pp. 119-126
-
-
Spencer, P.S.1
Palmer, V.S.2
Ludolph, A.C.3
-
10
-
-
0001499873
-
Kuru; clinical, pathological and epidemiological study of an acute progressive degenerative disease of the central nervous system among natives of the Eastern Highlands of New Guinea
-
Gajdusek, D.C.; Zigas, V. Kuru; clinical, pathological and epidemiological study of an acute progressive degenerative disease of the central nervous system among natives of the Eastern Highlands of New Guinea. Am. J. Med. 1959, 26, 442-469.
-
(1959)
Am. J. Med
, vol.26
, pp. 442-469
-
-
Gajdusek, D.C.1
Zigas, V.2
-
11
-
-
79959366068
-
Prions and protein-folding diseases
-
Norrby, E. Prions and protein-folding diseases. J. Intern. Med. 270, 1-14.
-
J. Intern. Med
, vol.270
, pp. 1-14
-
-
Norrby, E.1
-
12
-
-
0037039246
-
Clinical features and changing patterns of neurodegenerative disorders on Guam, 1997-2000
-
Galasko, D.; Salmon, D.P.; Craig, U.K.; Thal, L.J.; Schellenberg, G.; Wiederholt, W. Clinical features and changing patterns of neurodegenerative disorders on Guam, 1997-2000. Neurology 2002, 58, 90-97.
-
(2002)
Neurology
, vol.58
, pp. 90-97
-
-
Galasko, D.1
Salmon, D.P.2
Craig, U.K.3
Thal, L.J.4
Schellenberg, G.5
Wiederholt, W.6
-
13
-
-
33847406346
-
Two sites in the MAPT region confer genetic risk for Guam ALS/PDC and dementia
-
Sundar, P.D.; Yu, C.E.; Sieh, W.; Steinbart, E.; Garruto, R.M.; Oyanagi, K.; Craig, U.-K.; Bird, T.D.; Wijsman, E.M.; Galasko, D.R.; Schellenberg, G.D. Two sites in the MAPT region confer genetic risk for Guam ALS/PDC and dementia. Hum. Mol. Genet. 2007, 16, 295-306.
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 295-306
-
-
Sundar, P.D.1
Yu, C.E.2
Sieh, W.3
Steinbart, E.4
Garruto, R.M.5
Oyanagi, K.6
Craig, U.-K.7
Bird, T.D.8
Wijsman, E.M.9
Galasko, D.R.10
Schellenberg, G.D.11
-
14
-
-
61449229465
-
Mutation analyses in amyotrophic lateral sclerosis/parkinsonismdementia complex of the Kii peninsula, Japan
-
Tomiyama, H.; Kokubo, Y.; Sasaki, R. Li, Y.; Imamichi, Y.; Funayama, M.; Mizuno, Y.; Hattori, N.; Kuzuhara, S. Mutation analyses in amyotrophic lateral sclerosis/parkinsonismdementia complex of the Kii peninsula, Japan. Mov. Disord. 2008, 23, 2344-2348.
-
(2008)
Mov. Disord
, vol.23
, pp. 2344-2348
-
-
Tomiyama, H.1
Kokubo, Y.2
Sasaki, R.3
Li, Y.4
Imamichi, Y.5
Funayama, M.6
Mizuno, Y.7
Hattori, N.8
Kuzuhara, S.9
-
15
-
-
34547527287
-
TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD?
-
Hermosura, M.C.; Garruto, R.M. TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD? Biochim. Biophys. Acta 2007, 1772, 822-835.
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, pp. 822-835
-
-
Hermosura, M.C.1
Garruto, R.M.2
-
16
-
-
23844451376
-
A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders
-
Hermosura, M.C.; Nayakanti, H.; Dorovkov, M.V.; Calderon, F.R.; Ryazanov, A.G.; Haymer, D.S.; Garruto, R.M. A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders. Proc. Natl. Acad. Sci. USA 2005, 102, 11510-11515.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11510-11515
-
-
Hermosura, M.C.1
Nayakanti, H.2
Dorovkov, M.V.3
Calderon, F.R.4
Ryazanov, A.G.5
Haymer, D.S.6
Garruto, R.M.7
-
17
-
-
73949144503
-
TRPM7 is not associated with amyotrophic lateral sclerosis-parkinsonism dementia complex in the Kii peninsula of Japan
-
Hara, K.; Kokubo, Y.; Ishiura, H.; Fukuda, Y.; Miyashita, A.; Kuwano, R.; Sasaki, R.; Goto, J.; Nishizawa, M.; Kuzuhara, S.; Tsuji, S. TRPM7 is not associated with amyotrophic lateral sclerosis-parkinsonism dementia complex in the Kii peninsula of Japan. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010, 153B, 310-313.
-
(2010)
Am. J. Med. Genet. B Neuropsychiatr. Genet
, vol.153 B
, pp. 310-313
-
-
Hara, K.1
Kokubo, Y.2
Ishiura, H.3
Fukuda, Y.4
Miyashita, A.5
Kuwano, R.6
Sasaki, R.7
Goto, J.8
Nishizawa, M.9
Kuzuhara, S.10
Tsuji, S.11
-
18
-
-
0015402167
-
An appraisal of the neurotoxicity of cycad and the etiology of amyotrophic lateral sclerosis on Guam
-
Kurland, L.T. An appraisal of the neurotoxicity of cycad and the etiology of amyotrophic lateral sclerosis on Guam. Fed. Proc. 1972, 31, 1540-1542.
-
(1972)
Fed. Proc
, vol.31
, pp. 1540-1542
-
-
Kurland, L.T.1
-
19
-
-
33645527182
-
Magnesium deficiency over generations in rats with special references to the pathogenesis of the Parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam
-
Oyanagi, K.; Kawakami, E.; Kikuchi-Horie, K.; Ohara, K.; Ogata, K.; Takahama, S.; Wada, M.; Kihira, T.; Yasui, M. Magnesium deficiency over generations in rats with special references to the pathogenesis of the Parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam. Neuropathology 2006, 26, 115-128.
-
(2006)
Neuropathology
, vol.26
, pp. 115-128
-
-
Oyanagi, K.1
Kawakami, E.2
Kikuchi-Horie, K.3
Ohara, K.4
Ogata, K.5
Takahama, S.6
Wada, M.7
Kihira, T.8
Yasui, M.9
-
20
-
-
0029115427
-
Guamanian neurodegenerative disease: Investigation of the calcium metabolism/heavy metal hypothesis
-
Ahlskog, J.E.; Waring, S.C.; Kurland, L.T.; Petersen, R.C.; Moyer, T.P.; Harmsen, W.S.; Maraganore, D.M.; O'Brien, P.C.; Esteban-Santillan, C.; Bush, V. Guamanian neurodegenerative disease: Investigation of the calcium metabolism/heavy metal hypothesis. Neurology 1995, 45, 1340-1344.
-
(1995)
Neurology
, vol.45
, pp. 1340-1344
-
-
Ahlskog, J.E.1
Waring, S.C.2
Kurland, L.T.3
Petersen, R.C.4
Moyer, T.P.5
Harmsen, W.S.6
Maraganore, D.M.7
O'Brien, P.C.8
Esteban-Santillan, C.9
Bush, V.10
-
21
-
-
80055105792
-
Identification of toxic elements of cycads
-
Third World Medical Research Foundation: 1988, New York, NY, USA
-
Whiting, M. Identification of toxic elements of cycads. In Toxicity of Cycads; Implications for Neurodegenerative Diseases and Cancer, Transcripts of the Four Cycad Conferences; Third World Medical Research Foundation: 1988, New York, NY, USA.
-
Toxicity of Cycads; Implications For Neurodegenerative Diseases and Cancer, Transcripts of the Four Cycad Conferences
-
-
Whiting, M.1
-
22
-
-
80055110432
-
A neurotoxic amino acid in seeds of cycas circinali
-
Third World Medical Research Foundation:1988, New York, NY, USA
-
Bell, E.A.; Vega, A.; Nunn, P.B. A neurotoxic amino acid in seeds of cycas circinalis. In Toxicity of Cycads; Implications for Neurodegenerative Diseases and Cancer, Transcripts of the Four Cycad Conferences; Third World Medical Research Foundation:1988, New York, NY, USA.
-
Toxicity of Cycads; Implications For Neurodegenerative Diseases and Cancer, Transcripts of the Four Cycad Conferences
-
-
Bell, E.A.1
Vega, A.2
Nunn, P.B.3
-
23
-
-
0023181410
-
Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin
-
Spencer, P.S.; Nunn, P.B.; Hugon, J.; Ludolph, A.C.; Ross, S.M.; Roy, D.N.; Robertson, R.C. Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin. Science 1987, 237, 517-522.
-
(1987)
Science
, vol.237
, pp. 517-522
-
-
Spencer, P.S.1
Nunn, P.B.2
Hugon, J.3
Ludolph, A.C.4
Ross, S.M.5
Roy, D.N.6
Robertson, R.C.7
-
24
-
-
0041624017
-
Biomagnification of cycad neurotoxins in flying foxes: Implications for ALS-PDC in Guam
-
Banack, S.A.; Cox, P.A. Biomagnification of cycad neurotoxins in flying foxes: Implications for ALS-PDC in Guam. Neurology 2003, 61, 387-389.
-
(2003)
Neurology
, vol.61
, pp. 387-389
-
-
Banack, S.A.1
Cox, P.A.2
-
25
-
-
0023618089
-
Cycad use and motor neuron disease in Irian Jaya
-
Spencer, P.S.; Palmer, V.; Herman, A.; Asmedi, A. Cycad use and motor neuron disease in Irian Jaya. Lancet 1987, 2, 1273-1274.
-
(1987)
Lancet
, vol.2
, pp. 1273-1274
-
-
Spencer, P.S.1
Palmer, V.2
Herman, A.3
Asmedi, A.4
-
26
-
-
0023493499
-
Cycad use and motor neuron disease in Kii peninsula of Japan
-
Spencer, P.S.; Ohta, M.; Palmer, V. Cycad use and motor neuron disease in Kii peninsula of Japan. Lancet 1987, 2, 1462-1463.
-
(1987)
Lancet
, vol.2
, pp. 1462-1463
-
-
Spencer, P.S.1
Ohta, M.2
Palmer, V.3
-
27
-
-
0015403006
-
Cycasin in cycad materials used in Japan
-
Kobayashi, A. Cycasin in cycad materials used in Japan. Fed. Proc. 1972, 31, 1476 1477.
-
(1972)
Fed. Proc
, vol.31
, Issue.1476
, pp. 1477
-
-
Kobayashi, A.1
-
28
-
-
0026720427
-
Content of the neurotoxins cycasin (methylazoxymethanol β-D-glucoside) and BMAA (β-N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros
-
Kisby, G.E.; Ellison, M.; Spencer, P.S. Content of the neurotoxins cycasin (methylazoxymethanol β-D-glucoside) and BMAA (β-N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros. Neurology 1992, 42, 1336-1340.
-
(1992)
Neurology
, vol.42
, pp. 1336-1340
-
-
Kisby, G.E.1
Ellison, M.2
Spencer, P.S.3
-
29
-
-
79955104001
-
Genotoxicity and potential carcinogenicity of cyanobacterial toxins - a review
-
Zegura, B.; Straser, A.; Filipic, M. Genotoxicity and potential carcinogenicity of cyanobacterial toxins - a review. Mutat. Res. 2011,727, 16-41.
-
(2011)
Mutat. Res
, vol.727
, pp. 16-41
-
-
Zegura, B.1
Straser, A.2
Filipic, M.3
-
30
-
-
0023615370
-
Specific antagonism of excitotoxic action of 'uncommon' amino acids assayed in organotypic mouse cortical cultures
-
Ross, S.M.; Seelig, M.; Spencer, P.S. Specific antagonism of excitotoxic action of 'uncommon' amino acids assayed in organotypic mouse cortical cultures. Brain Res. 1987, 425, 120-127.
-
(1987)
Brain Res
, vol.425
, pp. 120-127
-
-
Ross, S.M.1
Seelig, M.2
Spencer, P.S.3
-
31
-
-
0028980731
-
The neurotoxin, beta-N methylamino-Lalanine (BMAA) interacts with the strychnine-insensitive glycine modulatory site of the N-methyl-D-aspartate receptor
-
Allen, C.N.; Omelchenko, I.; Ross, S.M.; Spencer, P. The neurotoxin, beta-N methylamino-Lalanine (BMAA) interacts with the strychnine-insensitive glycine modulatory site of the N-methyl-D-aspartate receptor. Neuropharmacology 1995, 34, 651-658.
-
(1995)
Neuropharmacology
, vol.34
, pp. 651-658
-
-
Allen, C.N.1
Omelchenko, I.2
Ross, S.M.3
Spencer, P.4
-
32
-
-
0024466387
-
Neurotoxicity of β-N-methylamino-L-alanine (BMAA) and β-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons
-
Weiss, J.H.; Koh, J.-Y.; Choi, D.W. Neurotoxicity of β-N-methylamino-L-alanine (BMAA) and β-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons. Brain Res. 1989, 497, 64-71.
-
(1989)
Brain Res
, vol.497
, pp. 64-71
-
-
Weiss, J.H.1
Koh, J.-Y.2
Choi, D.W.3
-
33
-
-
84858444240
-
β-N-Methylamino-L-alanine neurotoxicity: Requirement for bicarbonate as a cofactor
-
Weiss, J.H.; Choi, D.W. β-N-Methylamino-L-alanine neurotoxicity: Requirement for bicarbonate as a cofactor. Science 1994, 19, 973-975.
-
(1994)
Science
, vol.19
, pp. 973-975
-
-
Weiss, J.H.1
Choi, D.W.2
-
34
-
-
0023183817
-
Specific antagonism of behavioral action of 'uncommon' amino acids linked to motor-system diseases
-
Ross, S.M.; Spencer, P.S. Specific antagonism of behavioral action of 'uncommon' amino acids linked to motor-system diseases. Synapse 1987, 1, 248-253.
-
(1987)
Synapse
, vol.1
, pp. 248-253
-
-
Ross, S.M.1
Spencer, P.S.2
-
35
-
-
0023071602
-
Discovery and partial characterization of primate motor-system toxins
-
Spencer, P.S.; Hugon, J.; Ludolph, A.; Nunn, P.B.; Ross, S.M.; Roy, D.N.; Schaumburg, H.H. Discovery and partial characterization of primate motor-system toxins. Ciba Found. Symp. 1987, 126, 221-238.
-
(1987)
Ciba Found. Symp
, vol.126
, pp. 221-238
-
-
Spencer, P.S.1
Hugon, J.2
Ludolph, A.3
Nunn, P.B.4
Ross, S.M.5
Roy, D.N.6
Schaumburg, H.H.7
-
36
-
-
77956226668
-
Domoic acid as a developmental neurotoxin
-
Costa, L.G.; Giordano, G.; Faustman, E.M. Domoic acid as a developmental neurotoxin. Neurotoxicology, 2010, 31, 409-423.
-
(2010)
Neurotoxicology
, vol.31
, pp. 409-423
-
-
Costa, L.G.1
Giordano, G.2
Faustman, E.M.3
-
37
-
-
0025194683
-
Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels
-
Teitelbaum, J.S.; Zatorre, R.J.; Carpenter, S.; Gendron, D.; Evans, A.C.; Gjedde, A.; Cashman, N.R. Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels. N. Engl. J. Med. 1990, 322, 1781-1787.
-
(1990)
N. Engl. J. Med
, vol.322
, pp. 1781-1787
-
-
Teitelbaum, J.S.1
Zatorre, R.J.2
Carpenter, S.3
Gendron, D.4
Evans, A.C.5
Gjedde, A.6
Cashman, N.R.7
-
38
-
-
33646525183
-
Neurotoxic flying foxes as dietary items for the Chamorro people, Marianas Islands
-
Banack, S.A.; Murch, S.J.; Cox, P.A. Neurotoxic flying foxes as dietary items for the Chamorro people, Marianas Islands. J. Ethnopharmacol. 2006, 106, 97-104.
-
(2006)
J. Ethnopharmacol
, vol.106
, pp. 97-104
-
-
Banack, S.A.1
Murch, S.J.2
Cox, P.A.3
-
39
-
-
4644350389
-
Occurrence of beta-methylaminol-alanine (BMAA) in ALS/PDC patients from Guam
-
Murch, S.J.; Cox, P.A.; Banack, S.A.; Steele, J.C.; Sacks, O.W. Occurrence of beta-methylaminol-alanine (BMAA) in ALS/PDC patients from Guam. Acta Neurol. Scand. 2004, 110, 267-269.
-
(2004)
Acta Neurol. Scand
, vol.110
, pp. 267-269
-
-
Murch, S.J.1
Cox, P.A.2
Banack, S.A.3
Steele, J.C.4
Sacks, O.W.5
-
40
-
-
0008472850
-
Cycasin and BMAA: Candidate neurotoxins for western Pacific amyotrophic lateral sclerosis/Parkinsonism-dementia complex
-
Kisby, G.E.; Ross, S.M.; Spencer, P.S.; Gold, B.G.; Nunn, P.B.; Roy, D.N. Cycasin and BMAA: Candidate neurotoxins for western Pacific amyotrophic lateral sclerosis/Parkinsonism-dementia complex. Neurodegeneration 1992, 1, 73-82.
-
(1992)
Neurodegeneration
, vol.1
, pp. 73-82
-
-
Kisby, G.E.1
Ross, S.M.2
Spencer, P.S.3
Gold, B.G.4
Nunn, P.B.5
Roy, D.N.6
-
41
-
-
0343132521
-
Western Pacific amyotrophic lateral sclerosis: Putative role of cycad toxins
-
Hudson, A.J., Ed.; University of Toronto Press: Toronto, ON, Canada
-
Spencer, P.S.; Ross, S.M.; Kisby, G.; Roy, D.N. Western Pacific amyotrophic lateral sclerosis: putative role of cycad toxins. In Amyotrophic Lateral Sclerosis: Concepts in Pathogenesis and Etiology, Hudson, A.J., Ed.; University of Toronto Press: Toronto, ON, Canada,1990; pp. 263-295.
-
(1990)
Amyotrophic Lateral Sclerosis: Concepts In Pathogenesis and Etiology
, pp. 263-295
-
-
Spencer, P.S.1
Ross, S.M.2
Kisby, G.3
Roy, D.N.4
-
42
-
-
65749119593
-
Beta-N-methylaminoalanine (BMAA): Metabolism and metabolic effects in model systems and in neural and other tissues of the rat in vitro
-
Nunn, P.B.; Ponnusamy, M. Beta-N-methylaminoalanine (BMAA): Metabolism and metabolic effects in model systems and in neural and other tissues of the rat in vitro. Toxicon 2009, 54, 85-94.
-
(2009)
Toxicon
, vol.54
, pp. 85-94
-
-
Nunn, P.B.1
Ponnusamy, M.2
-
43
-
-
0345555532
-
Brain metabolism of β-N-methylamino-L-alanine (BMAA) and protection of excitotoxicity by GABA-uptake inhibitors
-
Kisby, G.E.; Nottingham, V.; Kayton, R.; Roy, D.N.; Spencer, P.S. Brain metabolism of β-N-methylamino-L-alanine (BMAA) and protection of excitotoxicity by GABA-uptake inhibitors. Soc. Neurosci. 1992, 18, 82.
-
(1992)
Soc. Neurosci
, vol.18
, pp. 82
-
-
Kisby, G.E.1
Nottingham, V.2
Kayton, R.3
Roy, D.N.4
Spencer, P.S.5
-
44
-
-
0024321552
-
High activity of cytochrome P-450-linked aminopyrine N-demethylase in mouse brain microsomes, and associated sex-related difference
-
Ravindranath, V.; Ananda Theertha Varada, H.K. High activity of cytochrome P-450-linked aminopyrine N-demethylase in mouse brain microsomes, and associated sex-related difference. Biochem. J. 1989, 261, 769-773.
-
(1989)
Biochem. J
, vol.261
, pp. 769-773
-
-
Ravindranath, V.1
Ananda, T.V.H.K.2
-
45
-
-
0023697638
-
Determination of β-N-methylamino-L-alanine (BMAA) in plant (Cycas circinalis L.) an animal tissue by precolumn derivatization with 9-fluorenylmethyl chloroformate (FMOC) and reversed-phase high-performance liquid chromotography
-
Kisby, G.E.; Roy, D.N.; Spencer, P.S. Determination of β-N-methylamino-L-alanine (BMAA) in plant (Cycas circinalis L.) an animal tissue by precolumn derivatization with 9-fluorenylmethyl chloroformate (FMOC) and reversed-phase high-performance liquid chromotography. J. Neurosci. Methods 1988, 26, 45-54.
-
(1988)
J. Neurosci. Methods
, vol.26
, pp. 45-54
-
-
Kisby, G.E.1
Roy, D.N.2
Spencer, P.S.3
-
46
-
-
0025819615
-
Protection and potentiation of MPTP-induced toxicity by cytochrome P-450 inhibitors and inducer: In vitro studies with brain slices
-
Pai, K.S.; Ravindranath, V. Protection and potentiation of MPTP-induced toxicity by cytochrome P-450 inhibitors and inducer: In vitro studies with brain slices. Brain Res. 1991, 555, 239-244.
-
(1991)
Brain Res
, vol.555
, pp. 239-244
-
-
Pai, K.S.1
Ravindranath, V.2
-
47
-
-
0023589127
-
The effect of 3,5,3'-triiodothyronine on leucine uptake and incorporation into protein in cultured neurons and subcellular fractions of rat central nervous system
-
Pickard, M.R.; Sinha, A.K.; Gullo, D.; Patel, N.; Hubank, M.; Ekins, R.P. The effect of 3,5,3'-triiodothyronine on leucine uptake and incorporation into protein in cultured neurons and subcellular fractions of rat central nervous system. Endocrinology 1987, 121, 2018-2026.
-
(1987)
Endocrinology
, vol.121
, pp. 2018-2026
-
-
Pickard, M.R.1
Sinha, A.K.2
Gullo, D.3
Patel, N.4
Hubank, M.5
Ekins, R.P.6
-
48
-
-
0032776086
-
Damage and repair of nerve cell DNA in toxic stress
-
Kisby, G.E.; Kabel, H.; Hugon, J.; Spencer, P. Damage and repair of nerve cell DNA in toxic stress. Drug Metab. Rev. 1999, 31, 589-618.
-
(1999)
Drug Metab. Rev
, vol.31
, pp. 589-618
-
-
Kisby, G.E.1
Kabel, H.2
Hugon, J.3
Spencer, P.4
-
49
-
-
0029793774
-
Motor neuron disease on Guam: Geographic and familial occurrence, 1956-85
-
Zhang, Z.X.; Anderson, D.W.; Mantel, N.; Román, G.C. Motor neuron disease on Guam: Geographic and familial occurrence, 1956-85. Acta Neurol. Scand. 1996, 94, 51-59.
-
(1996)
Acta Neurol. Scand
, vol.94
, pp. 51-59
-
-
Zhang, Z.X.1
Anderson, D.W.2
Mantel, N.3
Román, G.C.4
-
50
-
-
0001869812
-
-
Marcel Dekker, New York, NY, USA
-
Roman, G.C.; Zhang, Z.-X.; Ellenberg, J.A. The Neuroepidemiology of Parkinson's Disease; Marcel Dekker: 1995, New York, NY, USA.
-
(1995)
The Neuroepidemiology of Parkinson's Disease
-
-
Roman, G.C.1
Zhang, Z.-X.2
Ellenberg, J.A.3
-
51
-
-
84940029376
-
Neurolathyrism and neurocycadism
-
Dastur, D.K., Shahani, M., Bharucha, E.P., Eds.; Interprint: New Delhi, India, 1986; Section VI
-
Spencer, P.S.; Dastur, D.K. Neurolathyrism and neurocycadism. In Neurological Sciences-An Overview of Current Problems Section VI Tropical Neurology and NeurotoxicologyI; Dastur, D.K., Shahani, M., Bharucha, E.P., Eds.; Interprint: New Delhi, India, 1986; Section VI.
-
Neurological Sciences-An Overview of Current Problems Section VI Tropical Neurology and NeurotoxicologyI
-
-
Spencer, P.S.1
Dastur, D.K.2
-
52
-
-
80055101664
-
-
2nd ed.; Spencer, P.S., Schaumburg, H.H., Eds.; Oxford University Press: New York, NY, USA
-
Spencer, P.S.; Kisby, G.E.; Palmer, V.S.; Obendorf, P. Cycasin, Methylazoxymethanol, and related compounds. In Experimental and Clinical Neurotoxicology, 2nd ed.; Spencer, P.S., Schaumburg, H.H., Eds.; Oxford University Press: New York, NY, USA, 1999; pp. 436-447.
-
(1999)
Methylazoxymethanol, and Related Compounds. In Experimental and Clinical Neurotoxicology
, pp. 436-447
-
-
Spencer, P.S.1
Kisby, G.E.2
Palmer, V.S.3
Obendorf, P.C.4
-
53
-
-
0018830825
-
Carcinogenicity and hepatotoxicity of cycasin and its aglycone methylazoxymethanol acetate in nonhuman primates
-
Sieber, S.M.; Correa, P.; Dalgard, D.W.; McIntire, K.R.; Adamson, R.H. Carcinogenicity and hepatotoxicity of cycasin and its aglycone methylazoxymethanol acetate in nonhuman primates. J. Natl. Cancer Inst. 1980, 65, 177-189.
-
(1980)
J. Natl. Cancer Inst
, vol.65
, pp. 177-189
-
-
Sieber, S.M.1
Correa, P.2
Dalgard, D.W.3
McIntire, K.R.4
Adamson, R.H.5
-
54
-
-
0024832864
-
Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens
-
Adamson, R.H. Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens. Cancer Detect. Prev. 1989, 14, 215-219.
-
(1989)
Cancer Detect. Prev
, vol.14
, pp. 215-219
-
-
Adamson, R.H.1
-
55
-
-
0025255580
-
Selective degeneration of cerebellar cortical neurons caused by cycad neurotoxin, L-β-methylaminoalanine (L-BMAA), in rats
-
Seawright, A.A.; Brown, A.W.; Nolan, C.C.; Cavanagh, J.B. Selective degeneration of cerebellar cortical neurons caused by cycad neurotoxin, L-β-methylaminoalanine (L-BMAA), in rats. Neuropathol. Appl. Neurobiol. 1990, 16, 153-169.
-
(1990)
Neuropathol. Appl. Neurobiol
, vol.16
, pp. 153-169
-
-
Seawright, A.A.1
Brown, A.W.2
Nolan, C.C.3
Cavanagh, J.B.4
-
56
-
-
77954073901
-
Environmental neurotoxin-induced progressive model of parkinsonism in rats
-
Shen, W.B.; McDowell, K.A.; Siebert, A.A.; Clark, S.M.; Dugger, N.V.; Valentino, K.M.; Jinnah, H.A.; Sztalryd, C.; Fishman, P.S.; Shaw, C.A.; Jafri, M.S.; Yarowsky, P.J. Environmental neurotoxin-induced progressive model of parkinsonism in rats. Ann. Neurol. 2010, 68, 70-80.
-
(2010)
Ann. Neurol
, vol.68
, pp. 70-80
-
-
Shen, W.B.1
McDowell, K.A.2
Siebert, A.A.3
Clark, S.M.4
Dugger, N.V.5
Valentino, K.M.6
Jinnah, H.A.7
Sztalryd, C.8
Fishman, P.S.9
Shaw, C.A.10
Jafri, M.S.11
Yarowsky, P.J.12
-
57
-
-
78650913511
-
Neurotoxic cycad components and Western Pacific ALS/PDC
-
author reply 976
-
Spencer, P.S.; Lasarev, M.R.; Palmer, V.S.; Kisby, G.E. Neurotoxic cycad components and Western Pacific ALS/PDC. Ann. Neurol. 2010, 68, 975-976; author reply 976.
-
(2010)
Ann. Neurol
, vol.68
, pp. 975-976
-
-
Spencer, P.S.1
Lasarev, M.R.2
Palmer, V.S.3
Kisby, G.E.4
-
58
-
-
0033600443
-
Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: A case-control study. Caribbean Parkinsonism Study Group
-
Caparros-Lefebvre, D.; Elbaz, A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: A case-control study. Caribbean Parkinsonism Study Group. Lancet 1999, 354, 281-286.
-
(1999)
Lancet
, vol.354
, pp. 281-286
-
-
Caparros-Lefebvre, D.1
Elbaz, A.2
-
59
-
-
33750317010
-
Is atypical parkinsonism in the Caribbean caused by the consumption of Annonacae
-
Lannuzel, A.; Hoglinger, G.U.; Champy, P.; Michel, P.P.; Hirsch, E.C.; Ruberg, M. Is atypical parkinsonism in the Caribbean caused by the consumption of Annonacae? J. Neural Transm. Suppl. 2006, 60,153-157.
-
(2006)
J. Neural Transm
, vol.Suppl
, pp. 153-157
-
-
Lannuzel, A.1
Hoglinger, G.U.2
Champy, P.3
Michel, P.P.4
Hirsch, E.C.5
Ruberg, M.6
-
60
-
-
0027215081
-
Neurologic diseases associated with use of plant components with toxic potential
-
Spencer, P.S.; Ludolph, A.C.; Kisby, G.E. Neurologic diseases associated with use of plant components with toxic potential. Environ.Res. 1993, 62, 106-113.
-
(1993)
Environ.Res
, vol.62
, pp. 106-113
-
-
Spencer, P.S.1
Ludolph, A.C.2
Kisby, G.E.3
-
61
-
-
0342411001
-
Carcinogenic effects of cycad meal and cycasin, methylazoxymethanol glycoside, in rats and effects of cycasin in germfree rats
-
Laqueur, G.L. Carcinogenic effects of cycad meal and cycasin, methylazoxymethanol glycoside, in rats and effects of cycasin in germfree rats. Fed. Proc. 1964, 23, 1386-1388.
-
(1964)
Fed. Proc
, vol.23
, pp. 1386-1388
-
-
Laqueur, G.L.1
-
62
-
-
77957258837
-
Cancer epidemiology in the Pacific islands-past, present and future
-
Moore, M.A.; Baumann, F.; Foliaki, S.; Goodman, M.T.; Haddock, R.; Maraka, R.; Koroivueta, J.; Roder, D.; Vinit, T.; Whippy, H.J.; Sobue, T. Cancer epidemiology in the Pacific islands-past, present and future. Asian Pac. J. Cancer Prev. 2010, S2, 99-106.
-
(2010)
Asian Pac. J. Cancer Prev
, vol.S2
, pp. 99-106
-
-
Moore, M.A.1
Baumann, F.2
Foliaki, S.3
Goodman, M.T.4
Haddock, R.5
Maraka, R.6
Koroivueta, J.7
Roder, D.8
Vinit, T.9
Whippy, H.J.10
Sobue, T.11
-
63
-
-
34249071028
-
Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam
-
Borenstein, A.R.; Mortimer, J.A.; Schofield, E.; Wu, Y.; Salmon, D.P.; Gamst, A.; Olichney, J.; Thal, L.J.; Silbert, L.; Kaye, J.; Craig, U.L.; Schellenberg, G.D.; Galasko, D.R. Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam. Neurology 2007, 68, 1764-1771.
-
(2007)
Neurology
, vol.68
, pp. 1764-1771
-
-
Borenstein, A.R.1
Mortimer, J.A.2
Schofield, E.3
Wu, Y.4
Salmon, D.P.5
Gamst, A.6
Olichney, J.7
Thal, L.J.8
Silbert, L.9
Kaye, J.10
Craig, U.L.11
Schellenberg, G.D.12
Galasko, D.R.13
-
64
-
-
0002808017
-
Amyotrophic Lateral Sclerosis in Japan
-
System Disorders and Atrophy, Part 2 Vinken, P.J., Bruyn, G.W., Eds.; American Elsevier: New York, NY, USA
-
Shiraki, H.; Yase, Y. Amyotrophic Lateral Sclerosis in Japan. In Handbook of Clinical Neurology Vol 22 System Disorders and Atrophy, Part 2, Vinken, P.J., Bruyn, G.W., Eds.; American Elsevier: New York, NY, USA, 1975; pp. 353-419.
-
(1975)
In Handbook of Clinical Neurology
, vol.22
, pp. 353-419
-
-
Shiraki, H.1
Yase, Y.2
-
65
-
-
0033635551
-
Mitotic activation: A convergent mechanism for a cohort of neurodegenerative diseases
-
Husseman, J.W.; Nochlin, D.; Vincent, I. Mitotic activation: A convergent mechanism for a cohort of neurodegenerative diseases. Neurobiol. Aging 2000, 21, 815-828.
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 815-828
-
-
Husseman, J.W.1
Nochlin, D.2
Vincent, I.3
-
66
-
-
0027945591
-
Postnatal methylazoxymethanol: Sensitive periods and regional selectivity of effects
-
Sullivan-Jones, P.; Gouch, A.B.; Holson, R.R. Postnatal methylazoxymethanol: Sensitive periods and regional selectivity of effects. Neurotoxicol. Teratol. 1994, 16, 631-637.
-
(1994)
Neurotoxicol. Teratol
, vol.16
, pp. 631-637
-
-
Sullivan-Jones, P.1
Gouch, A.B.2
Holson, R.R.3
-
67
-
-
0642286567
-
The cell cycle and human neurodegenerative disease
-
Vincent, I.; Pae, C.I.; Hallows, J.L. The cell cycle and human neurodegenerative disease. Prog. Cell Cycle Res. 2003, 5, 31-41.
-
(2003)
Prog. Cell Cycle Res
, vol.5
, pp. 31-41
-
-
Vincent, I.1
Pae, C.I.2
Hallows, J.L.3
-
68
-
-
33947181594
-
Neuronal cell cycle re-entry mediates Alzheimer disease-type changes
-
McShea, A.; Lee, H.G.; Petersen, R.B.; Casadesus, G.; Vincent, I.; Linford, N.J.; Funk, J.O.; Shapiro, R.A.; Smith, M.A. Neuronal cell cycle re-entry mediates Alzheimer disease-type changes. Biochim. Biophys. Acta 2007, 1772, 467-472.
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, pp. 467-472
-
-
McShea, A.1
Lee, H.G.2
Petersen, R.B.3
Casadesus, G.4
Vincent, I.5
Linford, N.J.6
Funk, J.O.7
Shapiro, R.A.8
Smith, M.A.9
-
69
-
-
49549083587
-
Neuronal binucleation in Alzheimer disease hippocampus
-
Zhu, X.; Siedlak, S.L.; Wang, Y.; Perry, G.; Castellani, R.J.; Cohen, M.L.; Smith, M.A. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathol. Appl. Neurobiol. 2008, 34, 457-465.
-
(2008)
Neuropathol. Appl. Neurobiol
, vol.34
, pp. 457-465
-
-
Zhu, X.1
Siedlak, S.L.2
Wang, Y.3
Perry, G.4
Castellani, R.J.5
Cohen, M.L.6
Smith, M.A.7
-
70
-
-
25844476202
-
Early environmental origins of neurodegenerative disease in later life
-
Landrigan, P.J.; Sonawane, B.; Butler, R.N.; Trasande, L.; Callan, R.; Droller, D. Early environmental origins of neurodegenerative disease in later life. Environ. Health Perspect 2005, 113, 1230-1233.
-
(2005)
Environ. Health Perspect
, vol.113
, pp. 1230-1233
-
-
Landrigan, P.J.1
Sonawane, B.2
Butler, R.N.3
Trasande, L.4
Callan, R.5
Droller, D.6
-
71
-
-
78650709936
-
Cancer and neurodegeneration: Between the devil and the deep blue sea
-
Plun-Favreau, H.; Lewis, P.A.; Hardy, J.; Martins, L.M.; Wood, N.W. Cancer and neurodegeneration: Between the devil and the deep blue sea. PLoS Genet 2010, 6, e1001257.
-
(2010)
PLoS Genet
, vol.6
-
-
Plun-Favreau, H.1
Lewis, P.A.2
Hardy, J.3
Martins, L.M.4
Wood, N.W.5
-
72
-
-
77953801296
-
Genetic determinants at the interface of cancer and neurodegenerative disease
-
Morris, L.G.; Veeriah, S.; Chan, T.A. Genetic determinants at the interface of cancer and neurodegenerative disease. Oncogene 2010, 29, 3453-3464.
-
(2010)
Oncogene
, vol.29
, pp. 3453-3464
-
-
Morris, L.G.1
Veeriah, S.2
Chan, T.A.3
-
73
-
-
0014592032
-
Studies on methylazoxymethanol: Methylation of nucleic acids in the fetal rat brain
-
Nagata, Y.; Matsumoto, H. Studies on methylazoxymethanol: Methylation of nucleic acids in the fetal rat brain. Proc. Soc. Exp. Biol. Med. 1969, 132, 383-385.
-
(1969)
Proc. Soc. Exp. Biol. Med
, vol.132
, pp. 383-385
-
-
Nagata, Y.1
Matsumoto, H.2
-
74
-
-
0015291790
-
Quantitative changes with age in the DNA content of methylazoxymethanol-induced microencephalic rat brain
-
Matsumoto, H.; Spatz, M.; Laqueur, G.L. Quantitative changes with age in the DNA content of methylazoxymethanol-induced microencephalic rat brain. J. Neurochem. 1972, 19, 297-306.
-
(1972)
J. Neurochem
, vol.19
, pp. 297-306
-
-
Matsumoto, H.1
Spatz, M.2
Laqueur, G.L.3
-
75
-
-
20244379134
-
Molecular networks perturbed in a developmental animal model of brain injury
-
Kisby, G.E.; Standley, M.; Lu, X.; O'Malley, J.; Lin, B.; Muniz, J.; Luo, N.L.; Pattee, P.; Back, S.A.; Nagalla, S.R. Molecular networks perturbed in a developmental animal model of brain injury. Neurobiol. Dis. 2005, 19, 108-118.
-
(2005)
Neurobiol. Dis
, vol.19
, pp. 108-118
-
-
Kisby, G.E.1
Standley, M.2
Lu, X.3
O'Malley, J.4
Lin, B.5
Muniz, J.6
Luo, N.L.7
Pattee, P.8
Back, S.A.9
Nagalla, S.R.10
-
76
-
-
59149098643
-
DNA repair modulates the vulnerability of the developing brain to alkylating agents
-
Kisby, G.E.; Olivas, A.; Park, T.; Churchwell, M.; Doerge, D.; Samson, L.D.; Gerson, S.L.; Turker, M.S. DNA repair modulates the vulnerability of the developing brain to alkylating agents. DNA Repair 2009, 8, 400-412.
-
(2009)
DNA Repair
, vol.8
, pp. 400-412
-
-
Kisby, G.E.1
Olivas, A.2
Park, T.3
Churchwell, M.4
Doerge, D.5
Samson, L.D.6
Gerson, S.L.7
Turker, M.S.8
-
77
-
-
0026620267
-
The repair of DNA alkylation damage by methyltransferases and glycosylases
-
Samson, L.D. The repair of DNA alkylation damage by methyltransferases and glycosylases. Essays Biochem. 1992, 27, 69-78.
-
(1992)
Essays Biochem
, vol.27
, pp. 69-78
-
-
Samson, L.D.1
-
78
-
-
0017773793
-
Long-term persistence of O6-methylguanine in rat brain DNA
-
Kleihues, P.; Bucheler, J. Long-term persistence of O6-methylguanine in rat brain DNA. Nature 1977, 269, 625-626.
-
(1977)
Nature
, vol.269
, pp. 625-626
-
-
Kleihues, P.1
Bucheler, J.2
-
79
-
-
0035038501
-
Comparison of single- versus double-bolus treatments of O(6)-benzylguanine for depletion of O(6)-methylguanine DNA methyltransferase (MGMT) activity in vivo: Development of a novel fluorometric oligonucleotide assay for measurement of MGMT activity
-
Kreklau, E.L.; Liu, N.; Li, Z.; Cornetta, K.; Erickson, L.C. Comparison of single- versus double-bolus treatments of O(6)-benzylguanine for depletion of O(6)-methylguanine DNA methyltransferase (MGMT) activity in vivo: Development of a novel fluorometric oligonucleotide assay for measurement of MGMT activity. J. Pharmacol. Exp. Ther. 2001, 297, 524-530.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.297
, pp. 524-530
-
-
Kreklau, E.L.1
Liu, N.2
Li, Z.3
Cornetta, K.4
Erickson, L.C.5
-
80
-
-
78650499827
-
O6-Methylguanine induces altered proteins at the level of transcription in human cells
-
Burns, J.A.; Dreij, K.; Cartularo, L.; Scicchitano, D.A. O6-Methylguanine induces altered proteins at the level of transcription in human cells. Nucleic Acids Res. 2010, 38, 8178-8187.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 8178-8187
-
-
Burns, J.A.1
Dreij, K.2
Cartularo, L.3
Scicchitano, D.A.4
-
81
-
-
0029902186
-
6-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary human brain tumors
-
6-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary human brain tumors. Proc. Natl. Acad. Sci. USA 1996, 93, 6941-6946.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6941-6946
-
-
Silber, J.R.1
Blank, A.2
Bobola, M.S.3
Mueller, B.A.4
Kolstoe, D.D.5
Ojemann, G.A.6
Berger, M.S.7
-
82
-
-
34447304855
-
6-Methylguanine-DNA methyltransferase deficiency in developing brain: Implications for brain tumorigenesis
-
6-Methylguanine-DNA methyltransferase deficiency in developing brain: Implications for brain tumorigenesis. DNA Repair (Amst.) 2007, 6, 1127-1133.
-
(2007)
DNA Repair (Amst.)
, vol.6
, pp. 1127-1133
-
-
Bobola, M.S.1
Blank, A.2
Berger, M.S.3
Silber, J.R.4
-
83
-
-
33750130545
-
Proteomic analysis of the genotoxicant methylazoxymethanol (MAM) induced changes in the developing cerebellum
-
Kisby, G.E.; Standley, M.; Park, T.; Olivas, A.; Fei, S.; Jacob, T.; Reddy, A.; Lu, X.; Pattee, P.; Nagalla, S.R. Proteomic analysis of the genotoxicant methylazoxymethanol (MAM) induced changes in the developing cerebellum. J. Proteome Res. 2006, 5, 2656-2665.
-
(2006)
J. Proteome Res
, vol.5
, pp. 2656-2665
-
-
Kisby, G.E.1
Standley, M.2
Park, T.3
Olivas, A.4
Fei, S.5
Jacob, T.6
Reddy, A.7
Lu, X.8
Pattee, P.9
Nagalla, S.R.10
-
84
-
-
33750874719
-
Genotoxicants target distinct molecular networks in neonatal neurons. Environ
-
Kisby, G.E.; Olivas, A.; Standley, M.; Lu, X.; Pattee, P.; O'Malley, J.; Li, X.; Muniz, J.; Nagalla, R. Genotoxicants target distinct molecular networks in neonatal neurons. Environ. Health. Perspect. 2006, 114, 1703-1712.
-
(2006)
Health. Perspect
, vol.114
, pp. 1703-1712
-
-
Kisby, G.E.1
Olivas, A.2
Standley, M.3
Lu, X.4
Pattee, P.5
O'Malley, J.6
Li, X.7
Muniz, J.8
Nagalla, R.9
-
85
-
-
34548845831
-
Quantitative proteomics identifies surfactant-resistant alpha-synuclein in cerebral cortex of parkinsonism-dementia complex of Guam but not Alzheimer's disease or progressive supranuclear palsy
-
Yang, W.; Woltjer, R.L.; Sokal, I.; Pan, C.; Wang, Y.; Brodey, M.; Peskind, E.R.; Leverenz, J.B.; Zhang, J.; Perl, D.P.; Galasko, D.R.; Montine, T.J. Quantitative proteomics identifies surfactant-resistant alpha-synuclein in cerebral cortex of parkinsonism-dementia complex of Guam but not Alzheimer's disease or progressive supranuclear palsy. Am. J. Pathol. 2007, 171, 993-1002.
-
(2007)
Am. J. Pathol
, vol.171
, pp. 993-1002
-
-
Yang, W.1
Woltjer, R.L.2
Sokal, I.3
Pan, C.4
Wang, Y.5
Brodey, M.6
Peskind, E.R.7
Leverenz, J.B.8
Zhang, J.9
Perl, D.P.10
Galasko, D.R.11
Montine, T.J.12
-
86
-
-
62149107892
-
DNA damage and repair in Alzheimer's disease
-
Coppede, F.; Migliore, L. DNA damage and repair in Alzheimer's disease. Curr. Alzheimer Res. 2009, 6, 36-47.
-
(2009)
Curr. Alzheimer Res
, vol.6
, pp. 36-47
-
-
Coppede, F.1
Migliore, L.2
-
87
-
-
38049010515
-
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
-
Lovell, M.A.; Markesbery, W.R. Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Res. 2007, 35, 7497-7504.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7497-7504
-
-
Lovell, M.A.1
Markesbery, W.R.2
-
88
-
-
43249118458
-
DNA damage and repair: Relevance to mechanisms of neurodegeneration
-
Martin, L.J. DNA damage and repair: Relevance to mechanisms of neurodegeneration. J. Neuropathol. Exp. Neurol. 2008, 67, 377-387.
-
(2008)
J. Neuropathol. Exp. Neurol
, vol.67
, pp. 377-387
-
-
Martin, L.J.1
-
89
-
-
34147204519
-
Oxidative damage in nucleic acids and Parkinson's disease
-
Nakabeppu, Y.; Tsuchimoto, D.; Yamaguchi, H.; Sakumi, K. Oxidative damage in nucleic acids and Parkinson's disease. J. Neurosci. Res. 2007, 85, 919-934.
-
(2007)
J. Neurosci. Res
, vol.85
, pp. 919-934
-
-
Nakabeppu, Y.1
Tsuchimoto, D.2
Yamaguchi, H.3
Sakumi, K.4
-
90
-
-
79959569353
-
The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damagelinked manner
-
Kisby, G.E.; Fry, R.C.; Lasarev, M.R.; Bammler, T.K.; Beyer, R.P.; Churchwell, M.; Doerge, D.R.; Meira, L.B.; Palmer, V.S.; Ramos-Crawford, A.L.; et al. The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damagelinked manner. PLoS One 2011, 6, e20911.
-
(2011)
PLoS One
, vol.6
-
-
Kisby, G.E.1
Fry, R.C.2
Lasarev, M.R.3
Bammler, T.K.4
Beyer, R.P.5
Churchwell, M.6
Doerge, D.R.7
Meira, L.B.8
Palmer, V.S.9
Ramos-Crawford, A.L.10
-
91
-
-
0017367498
-
Excision of O6-methylguanine from DNA of various mouse tissues following a single injection of N-methyl-nitrosourea
-
Buecheler, J.; Kleihues, P. Excision of O6-methylguanine from DNA of various mouse tissues following a single injection of N-methyl-nitrosourea. Chem. Biol. Interact. 1977, 16, 325-333.
-
(1977)
Chem. Biol. Interact
, vol.16
, pp. 325-333
-
-
Buecheler, J.1
Kleihues, P.2
-
92
-
-
0020618087
-
Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea
-
Likhachev, A.J.; Alekandrov, V.A.; Anisimov, V.N.; Bespalov, V.G.; Korsakov, M.V.; Ovsyannikov, A.I.; Popovich, I.G.; Napalkov, N.P.; Tomatis, L. Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea. Int. J. Cancer 1983, 31, 779-784.
-
(1983)
Int. J. Cancer
, vol.31
, pp. 779-784
-
-
Likhachev, A.J.1
Alekandrov, V.A.2
Anisimov, V.N.3
Bespalov, V.G.4
Korsakov, M.V.5
Ovsyannikov, A.I.6
Popovich, I.G.7
Napalkov, N.P.8
Tomatis, L.9
-
93
-
-
0022827478
-
Microencephalic rats as a model for cognitive disorders
-
Balduini, W.; Cimino, M.; Lombardelli, G.; Abbracchio, M.P.; Peruzzi, G.; Cecchini, T.; Gazzanelli, G.C.; Cattabeni, F. Microencephalic rats as a model for cognitive disorders. Clin. Neuropharmacol. 1986, 9, S8-S18.
-
(1986)
Clin. Neuropharmacol
, vol.9
-
-
Balduini, W.1
Cimino, M.2
Lombardelli, G.3
Abbracchio, M.P.4
Peruzzi, G.5
Cecchini, T.6
Gazzanelli, G.C.7
Cattabeni, F.8
-
94
-
-
0031026537
-
Developmental models of brain dysfunctions induced by targeted cellular ablations with methylazoxymethanol
-
Cattabeni, F.; Di Luca, M. Developmental models of brain dysfunctions induced by targeted cellular ablations with methylazoxymethanol. Physiol. Rev. 1997, 77, 199-215.
-
(1997)
Physiol. Rev
, vol.77
, pp. 199-215
-
-
Cattabeni, F.1
Di Luca, M.2
-
95
-
-
0342411001
-
Carcinogenic effects of cycad meal and cycasin, methylazoxymethanol glycoside, in rats and effects of cycasin in germfree rats
-
Laqueur, G.L. Carcinogenic effects of cycad meal and cycasin, methylazoxymethanol glycoside, in rats and effects of cycasin in germfree rats. Fed. Proc. 1964, 23, 1386-1388.
-
(1964)
Fed. Proc
, vol.23
, pp. 1386-1388
-
-
Laqueur, G.L.1
-
96
-
-
0021780531
-
Animal model for colorectal cancer
-
Nigro, N.D. Animal model for colorectal cancer. Prog. Clin. Biol. Res. 1985, 186, 161-173.
-
(1985)
Prog. Clin. Biol. Res
, vol.186
, pp. 161-173
-
-
Nigro, N.D.1
-
97
-
-
0019129065
-
Amyotrophic lateral sclerosis among Chamorro migrants from Guam
-
Garruto, R.M.; Gadjusek, D.C.; Chen, K.-M. Amyotrophic lateral sclerosis among Chamorro migrants from Guam. Ann. Neurol. 1980, 8, 612-619.
-
(1980)
Ann. Neurol
, vol.8
, pp. 612-619
-
-
Garruto, R.M.1
Gadjusek, D.C.2
Chen, K.-M.3
-
98
-
-
0019495680
-
Amyotrophic lateral sclerosis and parkinsonism-dementia among Filipino migrants to Guam
-
Garruto, R.M.; Gadjusek, D.C.; Chen, K.-M. Amyotrophic lateral sclerosis and parkinsonism-dementia among Filipino migrants to Guam. Ann. Neurol. 1981, 10, 341-350.
-
(1981)
Ann. Neurol
, vol.10
, pp. 341-350
-
-
Garruto, R.M.1
Gadjusek, D.C.2
Chen, K.-M.3
-
99
-
-
0018404316
-
Neurofibrillary degeneration on Guam: Frequency in Chamorros and non Chamorros with no known neurological disease
-
Anderson, F.H.; Richardson, E.P.; Okazaki, H.; Brody, J.A. Neurofibrillary degeneration on Guam: Frequency in Chamorros and non Chamorros with no known neurological disease. Brain 1979, 102, 65-77.
-
(1979)
Brain
, vol.102
, pp. 65-77
-
-
Anderson, F.H.1
Richardson, E.P.2
Okazaki, H.3
Brody, J.A.4
-
100
-
-
80055104334
-
Does the cycad genotoxin MAM implicated in Guam ALS-PDC induce disease-relevant changes in mouse brain that includes olfaction
-
In press
-
Kisby, G.E.; Palmer, V.S.; Lasarev, M.R.; Fry, R.; Iordanov, M.; Magun, E.; Samson, L.; Spencer, P. Does the cycad genotoxin MAM implicated in Guam ALS-PDC induce disease-relevant changes in mouse brain that includes olfaction? Commun. Integr. Biol., In press.
-
Commun. Integr. Biol
-
-
Kisby, G.E.1
Palmer, V.S.2
Lasarev, M.R.3
Fry, R.4
Iordanov, M.5
Magun, E.6
Samson, L.7
Spencer, P.8
-
101
-
-
0026162861
-
Odor identification deficit of the Parkinsonism-dementia complex of Guam: Equivalence to that of Alzheimer's and idiopathic Parkinson's disease
-
Doty, R.L.; Perl, D.P.; Steele, J.C.; Chen, K.M.; Pierce, J.D., Jr.; Reyes, P.; Kurland, L.T. Odor identification deficit of the Parkinsonism-dementia complex of Guam: Equivalence to that of Alzheimer's and idiopathic Parkinson's disease. Neurology 1991, 41, 77-80.
-
(1991)
Neurology
, vol.41
, pp. 77-80
-
-
Doty, R.L.1
Perl, D.P.2
Steele, J.C.3
Chen, K.M.4
Pierce Jr., J.D.5
Reyes, P.6
Kurland, L.T.7
-
102
-
-
0031703666
-
Olfactory dysfunction in Guamanian ALS, parkinsonism, and dementia
-
Ahlskog, J.E.; Waring, S.C.; Petersen, R.C.; Esteban-Santillan, C.; Craig, U.K.; O'Brien, P.C.; Plevak, M.F.; Kurland, L.T. Olfactory dysfunction in Guamanian ALS, parkinsonism, and dementia. Neurology 1998, 51, 1672-1677.
-
(1998)
Neurology
, vol.51
, pp. 1672-1677
-
-
Ahlskog, J.E.1
Waring, S.C.2
Petersen, R.C.3
Esteban-Santillan, C.4
Craig, U.K.5
O'Brien, P.C.6
Plevak, M.F.7
Kurland, L.T.8
-
103
-
-
68649128146
-
Olfactory impairment in presymptomatic Alzheimer's disease
-
Wilson, R.S.; Arnold, S.E.; Schneider, J.A.; Boyle, P.A.; Buchman, A.S.; Bennett, D.A. Olfactory impairment in presymptomatic Alzheimer's disease. Ann. N. Y. Acad. Sci. 2009, 1170, 730-735.
-
(2009)
Ann. N. Y. Acad. Sci
, vol.1170
, pp. 730-735
-
-
Wilson, R.S.1
Arnold, S.E.2
Schneider, J.A.3
Boyle, P.A.4
Buchman, A.S.5
Bennett, D.A.6
-
104
-
-
80054099487
-
Motor and Non-motor Correlates of Olfactory Dysfunction In Parkinson's Disease
-
doi:10.1016/j.jns.2011.06.020. Published online: 24 June
-
Berendse, H.W.; Roos, D.S.; Raijmakers, P.; Doty, R.L. Motor and non-motor correlates of olfactory dysfunction in Parkinson's disease. J. Neurol. Sci. doi:10.1016/j.jns.2011.06.020. Published online: 24 June 2011.
-
(2011)
J. Neurol. Sci
-
-
Berendse, H.W.1
Roos, D.S.2
Raijmakers, P.3
Doty, R.L.4
-
105
-
-
0026209343
-
Olfactory dysfunction in three neurodegenerative diseases
-
Doty, R.L.; Perl, D.P.; Steele, J.C.; Chen, K.M.; Pierce, J.D., Jr.; Reyes, P.; Kurland, L.T. Olfactory dysfunction in three neurodegenerative diseases. Geriatrics 1991, 46S, 47-51.
-
(1991)
Geriatrics
, vol.46 S
, pp. 47-51
-
-
Doty, R.L.1
Perl, D.P.2
Steele, J.C.3
Chen, K.M.4
Pierce Jr., J.D.5
Reyes, P.6
Kurland, L.T.7
-
106
-
-
48949100108
-
Tumorigenesis and neurodegeneration: Two sides of the same coin?
-
Staropoli, J.F. Tumorigenesis and neurodegeneration: Two sides of the same coin? Bioessays 2008, 30, 719-727.
-
(2008)
Bioessays
, vol.30
, pp. 719-727
-
-
Staropoli, J.F.1
-
107
-
-
28244440252
-
Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology
-
Caricasole, A.; Bakker, A.; Copani, A.; Nicoletti, F.; Gaviraghi, G.; Terstappen, G.C. Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology. Biosci. Rep. 2005, 25, 309-327.
-
(2005)
Biosci. Rep
, vol.25
, pp. 309-327
-
-
Caricasole, A.1
Bakker, A.2
Copani, A.3
Nicoletti, F.4
Gaviraghi, G.5
Terstappen, G.C.6
-
108
-
-
37749047236
-
Glycogen synthase kinase-3beta, or a link between amyloid and tau pathology?
-
Muyllaert, D.; Kremer, A.; Jaworski, T.; Borghgraef, P.; Devijver, H.; Croes, S.; Dewachter, I.; van Leuven, F. Glycogen synthase kinase-3beta, or a link between amyloid and tau pathology? Genes Brain Behav. 2008, 7S, 57-66.
-
(2008)
Genes Brain Behav
, vol.7 S
, pp. 57-66
-
-
Muyllaert, D.1
Kremer, A.2
Jaworski, T.3
Borghgraef, P.4
Devijver, H.5
Croes, S.6
Dewachter, I.7
van Leuven, F.8
-
109
-
-
67149147457
-
A common biological mechanism in cancer and Alzheimer's disease?
-
Behrens, M.I.; Lendon, C.; Roe, C.M. A common biological mechanism in cancer and Alzheimer's disease? Curr. Alzheimer Res. 2009, 6, 196-204.
-
(2009)
Curr. Alzheimer Res
, vol.6
, pp. 196-204
-
-
Behrens, M.I.1
Lendon, C.2
Roe, C.M.3
-
110
-
-
78650914558
-
Tubulin-independent tau in Alzheimer's disease and cancer: Implications for disease pathogenesis and treatment
-
Souter, S.; Lee, G. Tubulin-independent tau in Alzheimer's disease and cancer: Implications for disease pathogenesis and treatment. Curr. Alzheimer Res. 2010, 7, 697-707.
-
(2010)
Curr. Alzheimer Res
, vol.7
, pp. 697-707
-
-
Souter, S.1
Lee, G.2
-
111
-
-
77951046871
-
High sensitivity to carcinogens in the brain of a mouse model of Alzheimer's disease
-
Serrano, J.; Fernandez, A.P.; Martinez-Murillo, R.; Martinez, A. High sensitivity to carcinogens in the brain of a mouse model of Alzheimer's disease. Oncogene, 2010, 29, 2165-2171.
-
(2010)
Oncogene
, vol.29
, pp. 2165-2171
-
-
Serrano, J.1
Fernandez, A.P.2
Martinez-Murillo, R.3
Martinez, A.4
-
112
-
-
76249088651
-
The signal pathways in azoxymethane-induced colon cancer and preventive implications
-
Chen, J.; Huang, X.F. The signal pathways in azoxymethane-induced colon cancer and preventive implications. Cancer Biol. Ther. 2009, 8, 1313-1317.
-
(2009)
Cancer Biol. Ther
, vol.8
, pp. 1313-1317
-
-
Chen, J.1
Huang, X.F.2
-
113
-
-
0033400226
-
Inhibition of O(6)-methylguanine-DNA methyltransferase increases azoxymethane-induced colonic tumors in rats
-
Wali, R.K.; Skarosi, S.; Hart, J.; Zhang, Y.; Dolan, M.E.; Moschel, R.C.; Nguyen, L.; Mustafi, R.; Brasitus, T.A.; Bissonnette, M. Inhibition of O(6)-methylguanine-DNA methyltransferase increases azoxymethane-induced colonic tumors in rats. Carcinogenesis 1999, 20, 2355-2360.
-
(1999)
Carcinogenesis
, vol.20
, pp. 2355-2360
-
-
Wali, R.K.1
Skarosi, S.2
Hart, J.3
Zhang, Y.4
Dolan, M.E.5
Moschel, R.C.6
Nguyen, L.7
Mustafi, R.8
Brasitus, T.A.9
Bissonnette, M.10
-
114
-
-
0034122380
-
Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane
-
Takahashi, M.; Nakatsugi, S.; Sugimura, T.; Wakabayashi, K. Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane. Carcinogenesis 2000, 21, 1117-1120.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1117-1120
-
-
Takahashi, M.1
Nakatsugi, S.2
Sugimura, T.3
Wakabayashi, K.4
-
115
-
-
0025924961
-
O6-Methylguanine inhibits the binding of transcription factors to DNA
-
Bonfanti, M.; Broggini, M.; Prontera, C.; D'Incalci, M. O6-Methylguanine inhibits the binding of transcription factors to DNA. Nucleic Acids Res. 1991, 19, 5739-5742.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 5739-5742
-
-
Bonfanti, M.1
Broggini, M.2
Prontera, C.3
D'incalci, M.4
-
116
-
-
0033178246
-
Effect of oxidative DNA damage in promoter elements on transcription factor binding
-
Ghosh, R.; Mitchell, D.L. Effect of oxidative DNA damage in promoter elements on transcription factor binding. Nucleic Acids Res. 1999, 27, 3213-3218.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 3213-3218
-
-
Ghosh, R.1
Mitchell, D.L.2
-
117
-
-
0037171657
-
The effect of DNA damage on the formation of protein/DNA complexes
-
Parsian, A.J.; Funk, M.C.; Tao, T.Y.; Hunt, C.R. The effect of DNA damage on the formation of protein/DNA complexes. Mutat. Res. 2002, 501, 105-113.
-
(2002)
Mutat. Res
, vol.501
, pp. 105-113
-
-
Parsian, A.J.1
Funk, M.C.2
Tao, T.Y.3
Hunt, C.R.4
-
118
-
-
0042026553
-
Oxidized guanine lesions as modulators of gene transcription. Altered p50 binding affinity and repair shielding by 7,8-dihydro-8-oxo-2'-deoxyguanosine lesions in the NF-kappaB promoter element
-
Hailer-Morrison, M.K.; Kotler, J.M.; Martin, B.D.; Sugden, K.D. Oxidized guanine lesions as modulators of gene transcription. Altered p50 binding affinity and repair shielding by 7,8-dihydro-8-oxo-2'-deoxyguanosine lesions in the NF-kappaB promoter element. Biochemistry 2003, 42, 9761-9770.
-
(2003)
Biochemistry
, vol.42
, pp. 9761-9770
-
-
Hailer-Morrison, M.K.1
Kotler, J.M.2
Martin, B.D.3
Sugden, K.D.4
-
119
-
-
34547119552
-
Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding
-
Yamini, B.; Yu, X.; Dolan, M.E.; Wu, M.H.; Kufe, D.W.; Weichselbaum, R.R. Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding. Cancer Res. 2007, 67, 6889-6898.
-
(2007)
Cancer Res
, vol.67
, pp. 6889-6898
-
-
Yamini, B.1
Yu, X.2
Dolan, M.E.3
Wu, M.H.4
Kufe, D.W.5
Weichselbaum, R.R.6
-
120
-
-
68249087104
-
Transcriptional mutagenesis induced by 8 oxoguanine in mammalian cells
-
Bregeon, D.; Peignon, P.A.; Sarasin, A. Transcriptional mutagenesis induced by 8 oxoguanine in mammalian cells. PLoS Genet. 2009, 5, e1000577.
-
(2009)
PLoS Genet
, vol.5
-
-
Bregeon, D.1
Peignon, P.A.2
Sarasin, A.3
-
121
-
-
79952017981
-
Transcriptional mutagenesis: Causes and involvement in tumour development
-
Bregeon, D.; Doetsch, P.W. Transcriptional mutagenesis: Causes and involvement in tumour development. Nat. Rev. Cancer 2011, 11, 218-227.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 218-227
-
-
Bregeon, D.1
Doetsch, P.W.2
-
122
-
-
67849085394
-
Epidemiological trends strongly suggest exposures as etiologic agents in the pathogenesis of sporadic Alzheimer's disease, diabetes mellitus, and non-alcoholic steatohepatitis
-
de la Monte, S.M.; Neusner, A.; Chu, J.; Lawton, M. Epidemiological trends strongly suggest exposures as etiologic agents in the pathogenesis of sporadic Alzheimer's disease, diabetes mellitus, and non-alcoholic steatohepatitis. J. Alzheimers Dis. 2009, 17, 519-529.
-
(2009)
J. Alzheimers Dis
, vol.17
, pp. 519-529
-
-
de la Monte, S.M.1
Neusner, A.2
Chu, J.3
Lawton, M.4
-
123
-
-
0021186726
-
Nitrosamines in bacon: A case study of balancing risks
-
McCutcheon, J.W. Nitrosamines in bacon: A case study of balancing risks. Public Health Rep. 1984, 99, 360-364.
-
(1984)
Public Health Rep
, vol.99
, pp. 360-364
-
-
McCutcheon, J.W.1
-
124
-
-
43049097903
-
Nutrition and gastric cancer risk: An update
-
Liu, C.; Russell, R.M. Nutrition and gastric cancer risk: An update. Nutr. Rev. 2008, 66, 237-249.
-
(2008)
Nutr. Rev
, vol.66
, pp. 237-249
-
-
Liu, C.1
Russell, R.M.2
-
125
-
-
0033565398
-
N-Nitroso compounds in the diet
-
Lijinsky, W. N-Nitroso compounds in the diet. Mutat. Res. 1999, 443, 129-138.
-
(1999)
Mutat. Res
, vol.443
, pp. 129-138
-
-
Lijinsky, W.1
-
126
-
-
79955463169
-
Chloramination of nitrogenous contaminants (pharmaceuticals and pesticides): NDMA and halogenated DBPs formation
-
Le Roux, J.; Gallard, H.; Croue, J.P. Chloramination of nitrogenous contaminants (pharmaceuticals and pesticides): NDMA and halogenated DBPs formation. Water Res.2011, 45, 3164-3174.
-
(2011)
Water Res
, vol.45
, pp. 3164-3174
-
-
Le Roux, J.1
Gallard, H.2
Croue, J.P.3
-
127
-
-
0030794913
-
Assessment of exposure to carcinogenic N-nitrosamines in the rubber industry
-
Oury, B.; Limasset, J.C.; Protois, J.C. Assessment of exposure to carcinogenic N-nitrosamines in the rubber industry. Int. Arch. Occup. Environ. Health 1997, 70, 261-271.
-
(1997)
Int. Arch. Occup. Environ. Health
, vol.70
, pp. 261-271
-
-
Oury, B.1
Limasset, J.C.2
Protois, J.C.3
-
128
-
-
0036898999
-
Genotoxicity of streptozotocin
-
Bolzan, A.D.; Bianchi, M.S. Genotoxicity of streptozotocin. Mutat. Res. 2002, 512, 121-134.
-
(2002)
Mutat. Res
, vol.512
, pp. 121-134
-
-
Bolzan, A.D.1
Bianchi, M.S.2
-
129
-
-
33847195328
-
Candidate mechanisms for chemotherapy-induced cognitive changes
-
Ahles, T.A.; Saykin, A.J. Candidate mechanisms for chemotherapy-induced cognitive changes. Nat. Rev. Cancer 2007, 7, 192-201.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 192-201
-
-
Ahles, T.A.1
Saykin, A.J.2
-
130
-
-
2642510727
-
Neuropsychological dysfunction associated with cancer and cancer therapies: A conceptual review of an emerging target
-
Wefel, J.S.; Kayl, A.E.; Meyers, C.A. Neuropsychological dysfunction associated with cancer and cancer therapies: A conceptual review of an emerging target. Br. J. Cancer 2004, 90, 1691-1696.
-
(2004)
Br. J. Cancer
, vol.90
, pp. 1691-1696
-
-
Wefel, J.S.1
Kayl, A.E.2
Meyers, C.A.3
-
131
-
-
80055121561
-
-
4th ed.; Clayton, G.D., Clayton, F.E., Eds.; John Wiley & Sons, Etobicoke, ON, Canada, Chapter 11
-
Thomson, M.A.; Green, C.R.; Rasma, B.B.; Holtshouser, J.L.; Hinderer, R.K.; Papciak, R.J.; Leung, H.; Howe, S.R.; Kuhn, T.D. N-Nitrosamines in Patty's Industrial Hygiene and Toxicology, 4th ed.; Clayton, G.D., Clayton, F.E., Eds.; John Wiley & Sons, Etobicoke, ON, Canada, 1993; Chapter 11, pp. 665-668.
-
(1993)
Nitrosamines In Patty's Industrial Hygiene and Toxicology
, pp. 665-668
-
-
Thomson, M.A.1
Green, C.R.2
Rasma, B.B.3
Holtshouser, J.L.4
Hinderer, R.K.5
Papciak, R.J.6
Leung, H.7
Howe, S.R.8
Kuhn, T.D.9
-
132
-
-
38449088511
-
Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: An experimental approach
-
Salkovic-Petrisic, M.; Hoyer, S. Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: An experimental approach. J. Neural Transm. Suppl. 2007, 72, 217-233.
-
(2007)
J. Neural Transm. Suppl
, vol.72
, pp. 217-233
-
-
Salkovic-Petrisic, M.1
Hoyer, S.2
-
133
-
-
68949161708
-
Mechanisms of nitrosamine-mediated neurodegeneration: Potential relevance to sporadic Alzheimer's disease
-
de la Monte, S.M.; Tong, M. Mechanisms of nitrosamine-mediated neurodegeneration: Potential relevance to sporadic Alzheimer's disease. J. Alzheimers Dis. 2009, 17, 817-825.
-
(2009)
J. Alzheimers Dis
, vol.17
, pp. 817-825
-
-
de la Monte, S.M.1
Tong, M.2
-
134
-
-
60349128460
-
Study of brain insulin receptors, ache activity and oxidative stress in rat model of ICV STZ induced dementia
-
Agrawal, R.; Tyagi, E.; Shukla, R.; Nath, C. A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia. Neuropharmacology 2009, 56, 779-787.
-
(2009)
Neuropharmacology
, vol.56
, pp. 779-787
-
-
Agrawal, R.1
Tyagi, E.2
Shukla, R.3
Nath, C.A.4
-
135
-
-
33845515523
-
Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency
-
Clodfelder-Miller, B.J.; Zmijewska, A.A.; Johnson, G.V.; Jope, R.S. Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency. Diabetes 2006, 55, 3320-3325.
-
(2006)
Diabetes
, vol.55
, pp. 3320-3325
-
-
Clodfelder-Miller, B.J.1
Zmijewska, A.A.2
Johnson, G.V.3
Jope, R.S.4
-
136
-
-
70949084806
-
Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease
-
Ke, Y.D.; Delerue, F.; Gladbach, A.; Gotz, J.; Ittner, L.M. Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease. PLoS One 2009, 4, e7917.
-
(2009)
PLoS One
, vol.4
-
-
Ke, Y.D.1
Delerue, F.2
Gladbach, A.3
Gotz, J.4
Ittner, L.M.5
-
137
-
-
33645100144
-
Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway
-
Salkovic-Petrisic, M.; Tribl, F.; Schmidt, M.; Hoyer, S.; Riederer, P. Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway. J. Neurochem. 2006, 96, 1005-1015.
-
(2006)
J. Neurochem
, vol.96
, pp. 1005-1015
-
-
Salkovic-Petrisic, M.1
Tribl, F.2
Schmidt, M.3
Hoyer, S.4
Riederer, P.5
-
138
-
-
77953004836
-
Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration
-
Tong, M.; Longato, L.; de la Monte, S.M. Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration. BMC Endocr. Disord. 2010, 10, 4.
-
(2010)
BMC Endocr. Disord
, vol.10
, pp. 4
-
-
Tong, M.1
Longato, L.2
de la Monte, S.M.3
-
139
-
-
70349309705
-
Immunohistochemical expression of IGF-I and GSK in the spinal cord of Kii and Guamanian ALS patients
-
Kihira, T.; Suzuki, A.; Kondo, T.; Wakayama, I.; Yoshida, S.; Hasegawa, K.; Garruto, R.M. Immunohistochemical expression of IGF-I and GSK in the spinal cord of Kii and Guamanian ALS patients. Neuropathology 2009, 29, 548-558.
-
(2009)
Neuropathology
, vol.29
, pp. 548-558
-
-
Kihira, T.1
Suzuki, A.2
Kondo, T.3
Wakayama, I.4
Yoshida, S.5
Hasegawa, K.6
Garruto, R.M.7
-
140
-
-
34147173277
-
Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment
-
Craft, S. Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment. Curr. Alzheimer Res. 2007, 4, 147-152.
-
(2007)
Curr. Alzheimer Res
, vol.4
, pp. 147-152
-
-
Craft, S.1
-
141
-
-
76549104226
-
Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer's disease
-
Eikelenboom, P.; van Exel, E.; Hoozemans, J.J.; Veerhuis, R.; Rozemuller, A.J.; van Gool, W.A. Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer's disease. Neurodegen. Dis. 2010, 7, 38-41.
-
(2010)
Neurodegen. Dis
, vol.7
, pp. 38-41
-
-
Eikelenboom, P.1
van Exel, E.2
Hoozemans, J.J.3
Veerhuis, R.4
Rozemuller, A.J.5
van Gool, W.A.6
-
142
-
-
65249103010
-
Smoking and risk for amyotrophic lateral sclerosis: Analysis of the EPIC cohort
-
Gallo, V.; Bueno-De-Mesquita, H.B.; Vermeulen, R.; Andersen, P.M.; Kyrozis, A.; Linseisen, J.; Kaaks, R.; Allen, N.E.; Roddam, A.W.; Boshuizen, H.C.; et al. Smoking and risk for amyotrophic lateral sclerosis: analysis of the EPIC cohort. Ann. Neurol. 2009, 65, 378-385.
-
(2009)
Ann. Neurol
, vol.65
, pp. 378-385
-
-
Gallo, V.1
Bueno-De-Mesquita, H.B.2
Vermeulen, R.3
Andersen, P.M.4
Kyrozis, A.5
Linseisen, J.6
Kaaks, R.7
Allen, N.E.8
Roddam, A.W.9
Boshuizen, H.C.10
-
143
-
-
65449185492
-
Prospective study of chemical exposures and amyotrophic lateral sclerosis
-
Weisskopf, M.G.; Morozova, N.; O'Reilly, E.J.; McCullough, M.L.; Calle, E.E.; Thun, M.J.; Ascherio, A. Prospective study of chemical exposures and amyotrophic lateral sclerosis. J. Neurol. Neurosur. Ps. 2009, 80, 558-561.
-
(2009)
J. Neurol. Neurosur. Ps
, vol.80
, pp. 558-561
-
-
Weisskopf, M.G.1
Morozova, N.2
O'Reilly, E.J.3
McCullough, M.L.4
Calle, E.E.5
Thun, M.J.6
Ascherio, A.7
-
144
-
-
0032966179
-
The Guam cycad toxin methylazoxymethanol damages neuronal DNA and modulates tau mRNA expression and excitotoxicity
-
Esclaire, F.; Kisby, G.E.; Milne, J.; Lesort, M.; Spencer, P.; Hugon, J. The Guam cycad toxin methylazoxymethanol damages neuronal DNA and modulates tau mRNA expression and excitotoxicity. Exp. Neurol. 1999, 155, 11-21.
-
(1999)
Exp. Neurol
, vol.155
, pp. 11-21
-
-
Esclaire, F.1
Kisby, G.E.2
Milne, J.3
Lesort, M.4
Spencer, P.5
Hugon, J.6
-
145
-
-
0032811459
-
Toxic neuronal apoptosis and modifications of tau and APP gene and protein expressions
-
Hugon, J.; Esclaire, F.; Lesort, M.; Kisby, G.; Spencer, P. Toxic neuronal apoptosis and modifications of tau and APP gene and protein expressions. Drug Metab. Rev. 1999, 31, 635-647.
-
(1999)
Drug Metab. Rev
, vol.31
, pp. 635-647
-
-
Hugon, J.1
Esclaire, F.2
Lesort, M.3
Kisby, G.4
Spencer, P.5
-
146
-
-
4344626578
-
A mechanism for slow release of biomagnified cyanobacterial neurotoxins and neurodegenerative disease in Guam
-
Murch, S.J.; Cox, P.A.; Banack, S.A. A mechanism for slow release of biomagnified cyanobacterial neurotoxins and neurodegenerative disease in Guam. Proc. Natl. Acad. Sci. USA 2004, 101, 12228-12231.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12228-12231
-
-
Murch, S.J.1
Cox, P.A.2
Banack, S.A.3
-
147
-
-
0026181912
-
Molecular biology and pathology of scrapie and the prion diseases of humans
-
Prusiner, S.B.; DeArmond, S.J. Molecular biology and pathology of scrapie and the prion diseases of humans. Brain Pathol. 1991, 1, 297-310.
-
(1991)
Brain Pathol
, vol.1
, pp. 297-310
-
-
Prusiner, S.B.1
Dearmond, S.J.2
-
148
-
-
58849140480
-
Ultrastructural study of florid plaques in variant Creutzfeldt-Jakob disease: A comparison with amyloid plaques in kuru, sporadic Creutzfeldt-Jakob disease and Gerstmann-Straussler-Scheinker disease. Neuropathol
-
Sikorska, B.; Liberski, P.P.; Sobow, T.; Budka, H.; Ironside, J.W. Ultrastructural study of florid plaques in variant Creutzfeldt-Jakob disease: A comparison with amyloid plaques in kuru, sporadic Creutzfeldt-Jakob disease and Gerstmann-Straussler-Scheinker disease. Neuropathol. Appl. Neurobiol. 2009, 35, 46-59.
-
(2009)
Appl. Neurobiol
, vol.35
, pp. 46-59
-
-
Sikorska, B.1
Liberski, P.P.2
Sobow, T.3
Budka, H.4
Ironside, J.W.5
|