Comparison of single- versus double-bolus treatments of O6-benzylguanine for depletion of O6-methylguanine DNA methyltransferase (MGMT) activity in vivo: Development of a novel fluorometric oligonucleotide assay for measurement of MGMT activity

Journal of Pharmacology and Experimental Therapeutics

Volumn 297, Issue 2, 2001, Pages 524-530

  Kreklau, Emiko L ^a,b   Liu, Naili ^a,b   Li, Zhaohua ^c   Cornetta, Kenneth ^a,b   Erickson, Leonard C ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 O BENZYLGUANINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; OLIGONUCLEOTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BRAIN; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; FLUOROMETRY; HUMAN; HUMAN CELL; IN VIVO STUDY; KIDNEY; LIVER; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; SPLEEN; TUMOR CELL LINE; TUMOR XENOGRAFT;

ANIMALS; ENZYME INHIBITORS; FEMALE; FLUOROMETRY; GUANINE; HELA CELLS; HUMANS; KINETICS; MALE; MICE; MICE, SCID; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; OLIGONUCLEOTIDES; REGENERATION; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0035038501     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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