메뉴 건너뛰기




Volumn 20, Issue 12, 1999, Pages 2355-2360

Inhibition of O6-methylguanine-DNA methyltransferase increases azoxymethane-induced colonic tumors in rats

Author keywords

[No Author keywords available]

Indexed keywords

6 O BENZYLGUANINE; AZOXYMETHANE; BETA CATENIN; MACROGOL 400; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLTRANSFERASE INHIBITOR; SODIUM CHLORIDE;

EID: 0033400226     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.12.2355     Document Type: Article
Times cited : (24)

References (37)
  • 1
    • 0031427089 scopus 로고    scopus 로고
    • Inhibitory effects of lemon grass (Cymbopogon citratus stapf) on formation of azoxymethane-induced DNA adducts and aberrant crypt foci in the rat colon
    • Suaeyun, R., Kinouchi, T., Arimochi, H., Vinitketkumnuen, U. and Ohnishi, Y. (1997) Inhibitory effects of lemon grass (Cymbopogon citratus Stapf) on formation of azoxymethane-induced DNA adducts and aberrant crypt foci in the rat colon. Carcinogenesis, 18, 949-955.
    • (1997) Carcinogenesis , vol.18 , pp. 949-955
    • Suaeyun, R.1    Kinouchi, T.2    Arimochi, H.3    Vinitketkumnuen, U.4    Ohnishi, Y.5
  • 6
    • 0028176008 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea
    • 6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea. Jpn J. Cancer Res., 85, 226-230.
    • (1994) Jpn J. Cancer Res. , vol.85 , pp. 226-230
    • Lijinsky, W.1    Pegg, A.E.2    Anver, M.R.3    Moschel, R.C.4
  • 7
    • 0025196019 scopus 로고
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc. Natl Acad. Sci. USA, 87, 5368-5372.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 5368-5372
    • Dolan, M.E.1    Moschel, R.C.2    Pegg, A.E.3
  • 9
    • 0030608633 scopus 로고    scopus 로고
    • 6-benzylguanine and its role in chemotherapy
    • 6-benzylguanine and its role in chemotherapy. Clin. Cancer Res., 3, 837-847.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 837-847
    • Dolan, M.E.1    Pegg, A.E.2
  • 11
    • 0025935178 scopus 로고
    • Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat
    • Sitrin, M.D., Halline, A.G., Abrahams, C. and Brasitus, T.A. (1991) Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat. Cancer Res., 51, 5608-5613.
    • (1991) Cancer Res. , vol.51 , pp. 5608-5613
    • Sitrin, M.D.1    Halline, A.G.2    Abrahams, C.3    Brasitus, T.A.4
  • 13
    • 0026080705 scopus 로고
    • Mutations in the K-ras oncogene induced by 1,2 dimelhylhydrazine in preneoplastic and neoplastic rat colonic mucosa
    • Jacoby, R.F., Llor, X., Teng, B.-B., Davidson, N.O. and Brasitus, T.A. (1991) Mutations in the K-ras oncogene induced by 1,2 dimelhylhydrazine in preneoplastic and neoplastic rat colonic mucosa. J. Clin. Invest., 87, 624-630.
    • (1991) J. Clin. Invest. , vol.87 , pp. 624-630
    • Jacoby, R.F.1    Llor, X.2    Teng, B.-B.3    Davidson, N.O.4    Brasitus, T.A.5
  • 15
    • 0031984227 scopus 로고    scopus 로고
    • β-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors
    • Takahashi, M., Fukuda, K., Sugimura, T. and Wakabayashi, K. (1998) β-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res., 58, 42-46.
    • (1998) Cancer Res. , vol.58 , pp. 42-46
    • Takahashi, M.1    Fukuda, K.2    Sugimura, T.3    Wakabayashi, K.4
  • 16
    • 0028299177 scopus 로고
    • Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane in Fischer-344 rats on high-risk diet
    • Shivapurkar, N., Tang, Z., Ferreira, A., Nasim, S., Garett, C. and Alabaster, O. (1994) Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane in Fischer-344 rats on high-risk diet. Carcinogenesis, 15, 775-778.
    • (1994) Carcinogenesis , vol.15 , pp. 775-778
    • Shivapurkar, N.1    Tang, Z.2    Ferreira, A.3    Nasim, S.4    Garett, C.5    Alabaster, O.6
  • 17
    • 0028362117 scopus 로고
    • Modulation of azoxymethane-induced mutational activation of ras protooncogenes by chemopreventive agents in colon carcinogenesis
    • Singh, J., Kulkarni, N., Kelloff, G. and Reddy, B.S. (1994) Modulation of azoxymethane-induced mutational activation of ras protooncogenes by chemopreventive agents in colon carcinogenesis. Carcinogenesis, 15, 1317-1323.
    • (1994) Carcinogenesis , vol.15 , pp. 1317-1323
    • Singh, J.1    Kulkarni, N.2    Kelloff, G.3    Reddy, B.S.4
  • 18
    • 0027426123 scopus 로고
    • K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis
    • Vivona, A.A., Shpitz, B., Medline, A., Bruce, W.R., Hay, K., Ward, M.A., Stern, H.S. and Gallinger, S. (1993) K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis. Carcinogenesis, 14, 1777-1781.
    • (1993) Carcinogenesis , vol.14 , pp. 1777-1781
    • Vivona, A.A.1    Shpitz, B.2    Medline, A.3    Bruce, W.R.4    Hay, K.5    Ward, M.A.6    Stern, H.S.7    Gallinger, S.8
  • 21
    • 0029901710 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis
    • 6-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis. Cancer Res., 56, 3244-3249.
    • (1996) Cancer Res. , vol.56 , pp. 3244-3249
    • Becker, K.1    Dosch, J.2    Gregel, C.M.3    Martin, B.A.4    Kaina, B.5
  • 25
    • 0028904619 scopus 로고
    • Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon
    • Zaidi, N.H., Pretlow, T.P., O'Riordan, M.A., Dumenco, L.L., Allay, E. and Gerson, S.L. (1995) Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon. Carcinogenesis, 16, 451-456.
    • (1995) Carcinogenesis , vol.16 , pp. 451-456
    • Zaidi, N.H.1    Pretlow, T.P.2    O'Riordan, M.A.3    Dumenco, L.L.4    Allay, E.5    Gerson, S.L.6
  • 26
    • 0021287405 scopus 로고
    • 6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents
    • 6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents. Cancer Invest., 2, 223-231.
    • (1984) Cancer Invest. , vol.2 , pp. 223-231
    • Pegg, A.E.1
  • 27
    • 0022931463 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues
    • 6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues. Carcinogenesis, 7, 745-749.
    • (1986) Carcinogenesis , vol.7 , pp. 745-749
    • Gerson, S.L.1    Trey, J.E.2    Miller, K.3    Berger, N.A.4
  • 28
    • 0022388918 scopus 로고
    • Differential susceptibility of rat and guinea pig colon mucosa DNA to methylation by methylazoxymethyl acetate in vivo
    • Sohn, O.S., Puz, C., Caswell, N. and Fiala, E.S. (1985) Differential susceptibility of rat and guinea pig colon mucosa DNA to methylation by methylazoxymethyl acetate in vivo. Cancer Lett., 29, 293-300.
    • (1985) Cancer Lett. , vol.29 , pp. 293-300
    • Sohn, O.S.1    Puz, C.2    Caswell, N.3    Fiala, E.S.4
  • 29
    • 0031284676 scopus 로고    scopus 로고
    • 6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC→AT transition in the K-ras oncogene
    • 6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC→AT transition in the K-ras oncogene. Carcinogenesis, 18, 1299-1302.
    • (1997) Carcinogenesis , vol.18 , pp. 1299-1302
    • Jackson, P.E.1    Hall, C.N.2    O'Connor, P.J.3    Cooper, D.P.4    Margison, G.P.5    Povey, A.C.6
  • 31
    • 0023262990 scopus 로고
    • Detection of high incidence of K-ras oncogenes during human colon tumorigenesis
    • Forrester, K., Almoguera, C., Han, K., Grizzle, W.E. and Perucho, M. (1987) Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature, 327, 298-303.
    • (1987) Nature , vol.327 , pp. 298-303
    • Forrester, K.1    Almoguera, C.2    Han, K.3    Grizzle, W.E.4    Perucho, M.5
  • 32
    • 0026480765 scopus 로고
    • Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: Earliest recognizable precursor lesions of experimental colon cancer
    • Stopera, S.A., Murphy, L.C. and Bird, R.P. (1992) Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: earliest recognizable precursor lesions of experimental colon cancer. Carcinogenesis, 13, 2081-2085.
    • (1992) Carcinogenesis , vol.13 , pp. 2081-2085
    • Stopera, S.A.1    Murphy, L.C.2    Bird, R.P.3
  • 33
    • 0026048311 scopus 로고
    • K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors: Effects of supplemental dietary calcium and vitamin D deficiency
    • Llor, X., Jacoby, R.F., Teng, B.B., Davidson, N.O., Sitrin, M.D. and Brasitus, T.A. (1991) K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors: effects of supplemental dietary calcium and vitamin D deficiency. Cancer Res., 51, 4305-4309.
    • (1991) Cancer Res. , vol.51 , pp. 4305-4309
    • Llor, X.1    Jacoby, R.F.2    Teng, B.B.3    Davidson, N.O.4    Sitrin, M.D.5    Brasitus, T.A.6
  • 34
    • 0032521433 scopus 로고    scopus 로고
    • Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
    • Sparks, A.B., Morin, P.J., Vogelstein, B. and Kinzler, K.W. (1998) Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res., 58, 1130-1134.
    • (1998) Cancer Res. , vol.58 , pp. 1130-1134
    • Sparks, A.B.1    Morin, P.J.2    Vogelstein, B.3    Kinzler, K.W.4
  • 36
    • 0026341034 scopus 로고
    • 6-methylguanine residues in different positions in and around codon 12 of rat H-ras
    • 6-methylguanine residues in different positions in and around codon 12 of rat H-ras. Cancer Res., 51, 5843-5850.
    • (1991) Cancer Res. , vol.51 , pp. 5843-5850
    • Georgiadis, P.1    Smith, C.A.2    Swann, P.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.