-
1
-
-
0031427089
-
Inhibitory effects of lemon grass (Cymbopogon citratus stapf) on formation of azoxymethane-induced DNA adducts and aberrant crypt foci in the rat colon
-
Suaeyun, R., Kinouchi, T., Arimochi, H., Vinitketkumnuen, U. and Ohnishi, Y. (1997) Inhibitory effects of lemon grass (Cymbopogon citratus Stapf) on formation of azoxymethane-induced DNA adducts and aberrant crypt foci in the rat colon. Carcinogenesis, 18, 949-955.
-
(1997)
Carcinogenesis
, vol.18
, pp. 949-955
-
-
Suaeyun, R.1
Kinouchi, T.2
Arimochi, H.3
Vinitketkumnuen, U.4
Ohnishi, Y.5
-
3
-
-
0029670679
-
6-benzylguanine or 1,3-bis(2-chloroethyl)-1-nitrosourea
-
6-benzylguanine or 1,3-bis(2-chloroethyl)-1-nitrosourea. Biochemistry, 35, 1328-1334.
-
(1996)
Biochemistry
, vol.35
, pp. 1328-1334
-
-
Srivenugopal, K.S.1
Yuan, X.H.2
Friedman, H.S.3
Ali-Osman, F.4
-
4
-
-
0032574814
-
Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes
-
Kawate, H., Sakumi, K., Tsuzuki, T., Nakatsuru, Y., Ishikawa, T., Takahashi, S., Takano, H., Noda, T. and Sekiguchi, M. (1998) Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proc. Natl Acad. Sci. USA, 95, 5116-5120.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 5116-5120
-
-
Kawate, H.1
Sakumi, K.2
Tsuzuki, T.3
Nakatsuru, Y.4
Ishikawa, T.5
Takahashi, S.6
Takano, H.7
Noda, T.8
Sekiguchi, M.9
-
6
-
-
0028176008
-
6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea
-
6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea. Jpn J. Cancer Res., 85, 226-230.
-
(1994)
Jpn J. Cancer Res.
, vol.85
, pp. 226-230
-
-
Lijinsky, W.1
Pegg, A.E.2
Anver, M.R.3
Moschel, R.C.4
-
7
-
-
0025196019
-
6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
-
6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc. Natl Acad. Sci. USA, 87, 5368-5372.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 5368-5372
-
-
Dolan, M.E.1
Moschel, R.C.2
Pegg, A.E.3
-
8
-
-
0018735230
-
Epithelial cell kinetics in the descending colon of the rat
-
Rijke, R.P., Plaisier, H.M. and Langendoen, N.J. (1979) Epithelial cell kinetics in the descending colon of the rat. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol., 30, 85-94.
-
(1979)
Virchows Arch. B Cell Pathol. Incl. Mol. Pathol.
, vol.30
, pp. 85-94
-
-
Rijke, R.P.1
Plaisier, H.M.2
Langendoen, N.J.3
-
9
-
-
0030608633
-
6-benzylguanine and its role in chemotherapy
-
6-benzylguanine and its role in chemotherapy. Clin. Cancer Res., 3, 837-847.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 837-847
-
-
Dolan, M.E.1
Pegg, A.E.2
-
10
-
-
0027189603
-
6-alkylguanine-DNA alkyltransferase and cellular proliferation in the rat colon
-
6-alkylguanine-DNA alkyltransferase and cellular proliferation in the rat colon. Carcinogenesis, 14, 1175-1179.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1175-1179
-
-
Jacoby, R.F.1
Bolt, M.J.2
Dolan, M.E.3
Otto, G.4
Dudeja, P.5
Sitrin, M.D.6
Brasitus, T.A.7
-
11
-
-
0025935178
-
Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat
-
Sitrin, M.D., Halline, A.G., Abrahams, C. and Brasitus, T.A. (1991) Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat. Cancer Res., 51, 5608-5613.
-
(1991)
Cancer Res.
, vol.51
, pp. 5608-5613
-
-
Sitrin, M.D.1
Halline, A.G.2
Abrahams, C.3
Brasitus, T.A.4
-
12
-
-
0028072163
-
Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid
-
Earnest, D.L., Holubec, H., Wali, R.K., Jolley, C.S., Bissonnette, M., Bhattacharyya, A.K., Roy, H., Khare, S. and Brasitus, T.A. (1994) Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid. Cancer Res., 54, 5071-5074.
-
(1994)
Cancer Res.
, vol.54
, pp. 5071-5074
-
-
Earnest, D.L.1
Holubec, H.2
Wali, R.K.3
Jolley, C.S.4
Bissonnette, M.5
Bhattacharyya, A.K.6
Roy, H.7
Khare, S.8
Brasitus, T.A.9
-
13
-
-
0026080705
-
Mutations in the K-ras oncogene induced by 1,2 dimelhylhydrazine in preneoplastic and neoplastic rat colonic mucosa
-
Jacoby, R.F., Llor, X., Teng, B.-B., Davidson, N.O. and Brasitus, T.A. (1991) Mutations in the K-ras oncogene induced by 1,2 dimelhylhydrazine in preneoplastic and neoplastic rat colonic mucosa. J. Clin. Invest., 87, 624-630.
-
(1991)
J. Clin. Invest.
, vol.87
, pp. 624-630
-
-
Jacoby, R.F.1
Llor, X.2
Teng, B.-B.3
Davidson, N.O.4
Brasitus, T.A.5
-
14
-
-
0031790262
-
Expression of G protein a subunits in normal rat colon and in azoxymethane-induced colonic neoplasms
-
Bolt, M.J.G., Mailloux, R.J., Rasenick, M.M., Wali, R.K., Skarosi, S., Bissonnelte, M., Brasitus, T.A. and Sitrin, M.D. (1998) Expression of G protein a subunits in normal rat colon and in azoxymethane-induced colonic neoplasms. Gastroenterology, 115, 1494-1503.
-
(1998)
Gastroenterology
, vol.115
, pp. 1494-1503
-
-
Bolt, M.J.G.1
Mailloux, R.J.2
Rasenick, M.M.3
Wali, R.K.4
Skarosi, S.5
Bissonnelte, M.6
Brasitus, T.A.7
Sitrin, M.D.8
-
15
-
-
0031984227
-
β-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors
-
Takahashi, M., Fukuda, K., Sugimura, T. and Wakabayashi, K. (1998) β-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res., 58, 42-46.
-
(1998)
Cancer Res.
, vol.58
, pp. 42-46
-
-
Takahashi, M.1
Fukuda, K.2
Sugimura, T.3
Wakabayashi, K.4
-
16
-
-
0028299177
-
Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane in Fischer-344 rats on high-risk diet
-
Shivapurkar, N., Tang, Z., Ferreira, A., Nasim, S., Garett, C. and Alabaster, O. (1994) Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane in Fischer-344 rats on high-risk diet. Carcinogenesis, 15, 775-778.
-
(1994)
Carcinogenesis
, vol.15
, pp. 775-778
-
-
Shivapurkar, N.1
Tang, Z.2
Ferreira, A.3
Nasim, S.4
Garett, C.5
Alabaster, O.6
-
17
-
-
0028362117
-
Modulation of azoxymethane-induced mutational activation of ras protooncogenes by chemopreventive agents in colon carcinogenesis
-
Singh, J., Kulkarni, N., Kelloff, G. and Reddy, B.S. (1994) Modulation of azoxymethane-induced mutational activation of ras protooncogenes by chemopreventive agents in colon carcinogenesis. Carcinogenesis, 15, 1317-1323.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1317-1323
-
-
Singh, J.1
Kulkarni, N.2
Kelloff, G.3
Reddy, B.S.4
-
18
-
-
0027426123
-
K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis
-
Vivona, A.A., Shpitz, B., Medline, A., Bruce, W.R., Hay, K., Ward, M.A., Stern, H.S. and Gallinger, S. (1993) K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis. Carcinogenesis, 14, 1777-1781.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1777-1781
-
-
Vivona, A.A.1
Shpitz, B.2
Medline, A.3
Bruce, W.R.4
Hay, K.5
Ward, M.A.6
Stern, H.S.7
Gallinger, S.8
-
20
-
-
0027337480
-
6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis
-
6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis. Proc. Natl Acad. Sci. USA, 90, 6468-6472.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 6468-6472
-
-
Nakatsuru, Y.1
Matsukuma, S.2
Nemoto, N.3
Sugano, H.4
Sekiguchi, M.5
Ishikawa, T.6
-
21
-
-
0029901710
-
6-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis
-
6-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis. Cancer Res., 56, 3244-3249.
-
(1996)
Cancer Res.
, vol.56
, pp. 3244-3249
-
-
Becker, K.1
Dosch, J.2
Gregel, C.M.3
Martin, B.A.4
Kaina, B.5
-
22
-
-
8944258921
-
Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent
-
Tsuzuki, T., Sakumi, K., Shiraishi, A., Kawate, H., Igarashi, H., Iwakuma, T., Tominaga, Y., Zhang, S., Shimizu, S., Ishikawa, T., Nakamura, K., Nakao, K., Katsuki, M. and Sekiguchi, M. (1996) Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent. Carcinogenesis, 17, 1215-1220.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1215-1220
-
-
Tsuzuki, T.1
Sakumi, K.2
Shiraishi, A.3
Kawate, H.4
Igarashi, H.5
Iwakuma, T.6
Tominaga, Y.7
Zhang, S.8
Shimizu, S.9
Ishikawa, T.10
Nakamura, K.11
Nakao, K.12
Katsuki, M.13
Sekiguchi, M.14
-
23
-
-
0031427721
-
High incidence of nitrosamine-induced tumorigenesis in mice lacking DNA repair methyltransferase
-
Iwakuma, T., Sakumi, K., Nakatsuru, Y., Kawate, H., Igarashi, H., Shiraishi, A., Tsuzuki, T., Ishikawa, T. and Sekiguchi, M. (1997) High incidence of nitrosamine-induced tumorigenesis in mice lacking DNA repair methyltransferase. Carcinogenesis, 18, 1631-1635.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1631-1635
-
-
Iwakuma, T.1
Sakumi, K.2
Nakatsuru, Y.3
Kawate, H.4
Igarashi, H.5
Shiraishi, A.6
Tsuzuki, T.7
Ishikawa, T.8
Sekiguchi, M.9
-
24
-
-
0030972856
-
Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice
-
Sakumi, K., Shiraishi, A., Shimizu, S., Tsuzuki, T., Ishikawa, T. and Sekiguchi, M. (1997) Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice. Cancer Res., 57, 2415-2418.
-
(1997)
Cancer Res.
, vol.57
, pp. 2415-2418
-
-
Sakumi, K.1
Shiraishi, A.2
Shimizu, S.3
Tsuzuki, T.4
Ishikawa, T.5
Sekiguchi, M.6
-
25
-
-
0028904619
-
Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon
-
Zaidi, N.H., Pretlow, T.P., O'Riordan, M.A., Dumenco, L.L., Allay, E. and Gerson, S.L. (1995) Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon. Carcinogenesis, 16, 451-456.
-
(1995)
Carcinogenesis
, vol.16
, pp. 451-456
-
-
Zaidi, N.H.1
Pretlow, T.P.2
O'Riordan, M.A.3
Dumenco, L.L.4
Allay, E.5
Gerson, S.L.6
-
26
-
-
0021287405
-
6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents
-
6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents. Cancer Invest., 2, 223-231.
-
(1984)
Cancer Invest.
, vol.2
, pp. 223-231
-
-
Pegg, A.E.1
-
27
-
-
0022931463
-
6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues
-
6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues. Carcinogenesis, 7, 745-749.
-
(1986)
Carcinogenesis
, vol.7
, pp. 745-749
-
-
Gerson, S.L.1
Trey, J.E.2
Miller, K.3
Berger, N.A.4
-
28
-
-
0022388918
-
Differential susceptibility of rat and guinea pig colon mucosa DNA to methylation by methylazoxymethyl acetate in vivo
-
Sohn, O.S., Puz, C., Caswell, N. and Fiala, E.S. (1985) Differential susceptibility of rat and guinea pig colon mucosa DNA to methylation by methylazoxymethyl acetate in vivo. Cancer Lett., 29, 293-300.
-
(1985)
Cancer Lett.
, vol.29
, pp. 293-300
-
-
Sohn, O.S.1
Puz, C.2
Caswell, N.3
Fiala, E.S.4
-
29
-
-
0031284676
-
6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC→AT transition in the K-ras oncogene
-
6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC→AT transition in the K-ras oncogene. Carcinogenesis, 18, 1299-1302.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1299-1302
-
-
Jackson, P.E.1
Hall, C.N.2
O'Connor, P.J.3
Cooper, D.P.4
Margison, G.P.5
Povey, A.C.6
-
30
-
-
0023256456
-
Prevalence of ras gene mutations in human colorectal cancers
-
Bos, J.L., Fearon, E.R., Hamilton, S.R., Verlaan-de Vries, M., van Boom, J.H., van der Eb, A.J. and Vogelstein, B. (1987) Prevalence of ras gene mutations in human colorectal cancers. Nature, 327, 293-297.
-
(1987)
Nature
, vol.327
, pp. 293-297
-
-
Bos, J.L.1
Fearon, E.R.2
Hamilton, S.R.3
Verlaan-De Vries, M.4
Van Boom, J.H.5
Van Der Eb, A.J.6
Vogelstein, B.7
-
31
-
-
0023262990
-
Detection of high incidence of K-ras oncogenes during human colon tumorigenesis
-
Forrester, K., Almoguera, C., Han, K., Grizzle, W.E. and Perucho, M. (1987) Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature, 327, 298-303.
-
(1987)
Nature
, vol.327
, pp. 298-303
-
-
Forrester, K.1
Almoguera, C.2
Han, K.3
Grizzle, W.E.4
Perucho, M.5
-
32
-
-
0026480765
-
Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: Earliest recognizable precursor lesions of experimental colon cancer
-
Stopera, S.A., Murphy, L.C. and Bird, R.P. (1992) Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: earliest recognizable precursor lesions of experimental colon cancer. Carcinogenesis, 13, 2081-2085.
-
(1992)
Carcinogenesis
, vol.13
, pp. 2081-2085
-
-
Stopera, S.A.1
Murphy, L.C.2
Bird, R.P.3
-
33
-
-
0026048311
-
K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors: Effects of supplemental dietary calcium and vitamin D deficiency
-
Llor, X., Jacoby, R.F., Teng, B.B., Davidson, N.O., Sitrin, M.D. and Brasitus, T.A. (1991) K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors: effects of supplemental dietary calcium and vitamin D deficiency. Cancer Res., 51, 4305-4309.
-
(1991)
Cancer Res.
, vol.51
, pp. 4305-4309
-
-
Llor, X.1
Jacoby, R.F.2
Teng, B.B.3
Davidson, N.O.4
Sitrin, M.D.5
Brasitus, T.A.6
-
34
-
-
0032521433
-
Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
-
Sparks, A.B., Morin, P.J., Vogelstein, B. and Kinzler, K.W. (1998) Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res., 58, 1130-1134.
-
(1998)
Cancer Res.
, vol.58
, pp. 1130-1134
-
-
Sparks, A.B.1
Morin, P.J.2
Vogelstein, B.3
Kinzler, K.W.4
-
35
-
-
0031911656
-
6-methylguanine lesion
-
6-methylguanine lesion. Mol. Cell. Biol., 18, 1660-1669.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1660-1669
-
-
Ali, R.B.1
Teo, A.K.2
Oh, H.K.3
Chuang, L.S.4
Ayi, T.C.5
Li, B.F.6
-
36
-
-
0026341034
-
6-methylguanine residues in different positions in and around codon 12 of rat H-ras
-
6-methylguanine residues in different positions in and around codon 12 of rat H-ras. Cancer Res., 51, 5843-5850.
-
(1991)
Cancer Res.
, vol.51
, pp. 5843-5850
-
-
Georgiadis, P.1
Smith, C.A.2
Swann, P.F.3
|