The catalytic subunit of human telomerase is a unique caspase-6 and caspase-7 substrate

Biochemistry

Volumn 50, Issue 42, 2011, Pages 9046-9055

  Soares, Joana ^a   Lowe, Margaret M ^a   Jarstfer, Michael B ^a  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INHIBITORS; CASPASE ACTIVATION; CASPASES; CATALYTIC SUBUNITS; CELLULAR PROLIFERATIONS; CLEAVAGE SITES; CULTURED CELL; DOWN-REGULATION; HUMAN TELOMERASE; OLD WORLDS; POST-TRANSLATION MODIFICATION; PROTEIN-PROTEIN INTERACTIONS; REVERSE TRANSCRIPTASES; RIBONUCLEOPROTEIN COMPLEX; TARGET PROTEINS; TELOMERASE; TELOMERASE ACTIVITY; TELOMERIC DNA;

CELL PROLIFERATION; MAMMALS; PROTEINS;

CELL DEATH;

APOPTOSIS INHIBITOR; CASPASE 6; CASPASE 7; TELOMERASE REVERSE TRANSCRIPTASE;

APOPTOSIS; ARTICLE; CELL STRAIN HEK293; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; LEUKEMIA CELL; MUTAGENESIS; NONHUMAN; PRIMATE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; ASPARTIC ACID; CASPASE 6; CASPASE 7; CATALYTIC DOMAIN; DOWN-REGULATION; GLUTAMIC ACID; HEK293 CELLS; HUMANS; JURKAT CELLS; K562 CELLS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RABBITS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TELOMERASE;

AMNIOTA; CERCOPITHECIDAE; PRIMATES;

EID: 80055016780     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2010398     Document Type: Article

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