-
1
-
-
0000049842
-
The remaking of chromosomes
-
Müller HJ. The remaking of chromosomes. Collecting Net 1938; 13:181-198.
-
(1938)
Collecting Net
, vol.13
, pp. 181-198
-
-
Müller, H.J.1
-
2
-
-
0001294157
-
The stability of broken ends of chromosomes in Zea mays
-
McClintock B. The stability of broken ends of chromosomes in Zea mays. Genetics 1941; 26:234-282.
-
(1941)
Genetics
, vol.26
, pp. 234-282
-
-
McClintock, B.1
-
4
-
-
0034597794
-
Telomere states and cell fates
-
Blackburn EH. Telomere states and cell fates. Nature 2000; 408:53-56.
-
(2000)
Nature
, vol.408
, pp. 53-56
-
-
Blackburn, E.H.1
-
5
-
-
33745862398
-
The biogenesis and regulation of telomerase holoenzymes
-
Collins K. The biogenesis and regulation of telomerase holoenzymes. Nature reviews Mol Cell Biol 2006; 7:484-494.
-
(2006)
Nature reviews Mol Cell Biol
, vol.7
, pp. 484-494
-
-
Collins, K.1
-
7
-
-
19844382620
-
Senescence and immortalization: Role of telomeres and telomerase
-
Shay JW, Wright WE. Senescence and immortalization: role of telomeres and telomerase. Carcinogenesis 2005; 26:867-874.
-
(2005)
Carcinogenesis
, vol.26
, pp. 867-874
-
-
Shay, J.W.1
Wright, W.E.2
-
9
-
-
10344229445
-
Regulation of cellular response to oncogenic and oxidative stress by Seladin-1
-
Wu C, Miloslavskaya I, Demontis S, Maestro R, Galaktionov K. Regulation of cellular response to oncogenic and oxidative stress by Seladin-1. Nature 2004; 432:640-645.
-
(2004)
Nature
, vol.432
, pp. 640-645
-
-
Wu, C.1
Miloslavskaya, I.2
Demontis, S.3
Maestro, R.4
Galaktionov, K.5
-
12
-
-
23244461708
-
Oncogene-induced senescence as an initial barrier in lymphoma development
-
Braig M, Lee S, Loddenkemper C, et al. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 2005; 436:660-665.
-
(2005)
Nature
, vol.436
, pp. 660-665
-
-
Braig, M.1
Lee, S.2
Loddenkemper, C.3
-
13
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen Z, Trotman LC, Shaffer D, et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 2005; 436:725-730.
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
-
14
-
-
34548771087
-
Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation
-
Wu CH, van Riggelen J, Yetil A, Fan AC, Bachireddy P, Felsher DW. Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. Proc Natl Acad Sci USA 2007; 104:13028-13033.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13028-13033
-
-
Wu, C.H.1
van Riggelen, J.2
Yetil, A.3
Fan, A.C.4
Bachireddy, P.5
Felsher, D.W.6
-
15
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W, Zender L, Miething C, et al. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007; 445:656-660.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
-
16
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
Ventura A, Kirsch DG, McLaughlin ME, et al. Restoration of p53 function leads to tumour regression in vivo. Nature 2007; 445:661-665.
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
-
17
-
-
34547941973
-
The common biology of cancer and ageing
-
Finkel T, Serrano M, Blasco MA. The common biology of cancer and ageing. Nature 2007; 448:767-774.
-
(2007)
Nature
, vol.448
, pp. 767-774
-
-
Finkel, T.1
Serrano, M.2
Blasco, M.A.3
-
18
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar AG, Ouellette M, Frolkis M, et al. Extension of life-span by introduction of telomerase into normal human cells. Science 1998; 279:349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
-
19
-
-
0037148328
-
Telomerase is not an oncogene
-
Harley CB. Telomerase is not an oncogene. Oncogene 2002; 21:494-502.
-
(2002)
Oncogene
, vol.21
, pp. 494-502
-
-
Harley, C.B.1
-
20
-
-
0032828652
-
Inhibition of telomerase limits the growth of human cancer cells
-
Hahn WC, Stewart SA, Brooks MW, et al. Inhibition of telomerase limits the growth of human cancer cells. Nat Med 1999; 10:1164-1170.
-
(1999)
Nat Med
, vol.10
, pp. 1164-1170
-
-
Hahn, W.C.1
Stewart, S.A.2
Brooks, M.W.3
-
21
-
-
0033455559
-
Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
-
Herbert B, Pitts AE, Baker SI, et al. Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death. Proc Natl Acad Sci USA 1999; 96:14276-14281.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14276-14281
-
-
Herbert, B.1
Pitts, A.E.2
Baker, S.I.3
-
22
-
-
0033568462
-
Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
-
Zhang X, Mar V, Zhou W, Harrington L, Robinson MO. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genes Dev 1999; 13:2388-2399.
-
(1999)
Genes Dev
, vol.13
, pp. 2388-2399
-
-
Zhang, X.1
Mar, V.2
Zhou, W.3
Harrington, L.4
Robinson, M.O.5
-
23
-
-
33748917567
-
Telomerase, and Human Disease
-
Artandi SE. Telomerase, and Human Disease. N Engl J Med 2006; 355:1195-1197.
-
(2006)
N Engl J Med
, vol.355
, pp. 1195-1197
-
-
Artandi, S.E.1
-
24
-
-
15944422499
-
Mutations in hTERT, the gene for telomerase reverse transcriptase, in aplastic anemia
-
Yamaguchi H, Calado RT, Ly H, et al. Mutations in hTERT, the gene for telomerase reverse transcriptase, in aplastic anemia. N Engl J Med 2005; 352:1413-1424.
-
(2005)
N Engl J Med
, vol.352
, pp. 1413-1424
-
-
Yamaguchi, H.1
Calado, R.T.2
Ly, H.3
-
25
-
-
34250614359
-
Adult-onset pulmonary fibrosis caused by mutations in telomerase
-
Tsakiri KD, CronkhiteJT, Kuan PJ, et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc Natl Acad Sci USA 2007; 104:7552-7557.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7552-7557
-
-
Tsakiri, K.D.1
Cronkhite, J.T.2
Kuan, P.J.3
-
26
-
-
17144420804
-
Mice with bad ends: Mouse models for the study of telomeres and telomerase in cancer and aging
-
Blasco MA. Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging. EMBO J 2005; 24:1095-1103.
-
(2005)
EMBO J
, vol.24
, pp. 1095-1103
-
-
Blasco, M.A.1
-
27
-
-
33745679352
-
Telomerase therapeutics for cancer: Challenges and new directions
-
Shay JW, Wright WE. Telomerase therapeutics for cancer: challenges and new directions. Nat Rev Drug Discov 2006; 7:577-584.
-
(2006)
Nat Rev Drug Discov
, vol.7
, pp. 577-584
-
-
Shay, J.W.1
Wright, W.E.2
-
28
-
-
13844272923
-
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage
-
Santos JH, Meyer N, Skorvaga M, et al. Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell 2004; 3:399-411.
-
(2004)
Aging Cell
, vol.3
, pp. 399-411
-
-
Santos, J.H.1
Meyer, N.2
Skorvaga, M.3
-
29
-
-
33744745014
-
Mitochondial localization of telomerase as determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptpsis
-
Santos JH, Meyer JN, Van Houten B. Mitochondial localization of telomerase as determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptpsis. Hum Mol Genet 2006; 15:1757-1768.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1757-1768
-
-
Santos, J.H.1
Meyer, J.N.2
Van Houten, B.3
-
30
-
-
1842611977
-
Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells
-
Haendeler J, Hoffmann J, Diehl JF, et al. Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells. Circ Res 2004; 94:768-775.
-
(2004)
Circ Res
, vol.94
, pp. 768-775
-
-
Haendeler, J.1
Hoffmann, J.2
Diehl, J.F.3
-
31
-
-
0037064011
-
Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis
-
Gorbunova V, Seluanov A, Pereira-Smith OM. Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. J Biol Chem 2002; 277:38540-38549.
-
(2002)
J Biol Chem
, vol.277
, pp. 38540-38549
-
-
Gorbunova, V.1
Seluanov, A.2
Pereira-Smith, O.M.3
-
32
-
-
0037390962
-
TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability
-
Zhang P, Chan SL, Fu W, Mendoza M, Mattson MP. TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability. FASEB J 2003; 17:767-769.
-
(2003)
FASEB J
, vol.17
, pp. 767-769
-
-
Zhang, P.1
Chan, S.L.2
Fu, W.3
Mendoza, M.4
Mattson, M.P.5
-
33
-
-
33746851957
-
hTERT: A novel endogenous inhibitor of the mitochondrial cell death pathway
-
Massard C, Zermati Y, Pauleau AL, et al. hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway. Oncogene 2006; 25:4505-4514.
-
(2006)
Oncogene
, vol.25
, pp. 4505-4514
-
-
Massard, C.1
Zermati, Y.2
Pauleau, A.L.3
-
34
-
-
45949096290
-
TERT promotes cellular and organismal survival independently of telomerase activity
-
Jan 28; [Epub ahead of print
-
Lee J, Sung YH, Cheong C, et al. TERT promotes cellular and organismal survival independently of telomerase activity. Oncogene 2008 Jan 28; [Epub ahead of print].
-
(2008)
Oncogene
-
-
Lee, J.1
Sung, Y.H.2
Cheong, C.3
-
35
-
-
24944460598
-
Shelterin: The protein complex that shapes and safeguards human telomeres
-
de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 2005; 19:2100-2110.
-
(2005)
Genes Dev
, vol.19
, pp. 2100-2110
-
-
de Lange, T.1
-
36
-
-
34249989400
-
Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres
-
Meier A, Fiegler H, Munoz P, et al. Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres. EMBO J 2007; 26:2707-2718.
-
(2007)
EMBO J
, vol.26
, pp. 2707-2718
-
-
Meier, A.1
Fiegler, H.2
Munoz, P.3
-
37
-
-
33750801681
-
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres
-
Verdun RE, Karlseder J. The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell 2006; 127:709-720.
-
(2006)
Cell
, vol.127
, pp. 709-720
-
-
Verdun, R.E.1
Karlseder, J.2
-
38
-
-
1642602686
-
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks
-
Sedelnikova OA, Horikawa I, Zimonjic DB, Popescu NC, Bonner WM, Barrett JC. Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks. Nat Cell Biol 2004; 6:168-170.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 168-170
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Zimonjic, D.B.3
Popescu, N.C.4
Bonner, W.M.5
Barrett, J.C.6
-
39
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, et al. A DNA damage checkpoint response in telomere-initiated senescence. Nature 2003; 426:194-198.
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d'Adda di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
-
40
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
Takai H, Smogorzewska A, de Lange T. DNA damage foci at dysfunctional telomeres. Curr Biol 2003; 13:1549-1556.
-
(2003)
Curr Biol
, vol.13
, pp. 1549-1556
-
-
Takai, H.1
Smogorzewska, A.2
de Lange, T.3
-
41
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M, Nunez S, Heard E, et al. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 2003; 113:703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
-
42
-
-
0043199578
-
Telomerase maintains telomere structure in normal human cells
-
Masutomi K, Yu EY, Khurts S, et al. Telomerase maintains telomere structure in normal human cells. Cell 2003; 114:241-253.
-
(2003)
Cell
, vol.114
, pp. 241-253
-
-
Masutomi, K.1
Yu, E.Y.2
Khurts, S.3
-
43
-
-
0141525391
-
Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends
-
Stellwagen AE, Haimberger ZW, Veatch JR, Gottschling DE. Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev 2003; 17:2384-2395.
-
(2003)
Genes Dev
, vol.17
, pp. 2384-2395
-
-
Stellwagen, A.E.1
Haimberger, Z.W.2
Veatch, J.R.3
Gottschling, D.E.4
-
44
-
-
0036312043
-
Interactions between telomerase and primase physically link the telomere and chromosome replication machinery
-
Ray S, Karamysheva Z, Wang L, Shippen DE, Price CM. Interactions between telomerase and primase physically link the telomere and chromosome replication machinery. Mol Cell Biol 2002; 22:5859-5868.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5859-5868
-
-
Ray, S.1
Karamysheva, Z.2
Wang, L.3
Shippen, D.E.4
Price, C.M.5
-
45
-
-
0242412194
-
Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation
-
Sharma GG, Hwang KK, Pandita RK, et al. Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. Mol Cell Biol 2003; 23:8363-8376.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8363-8376
-
-
Sharma, G.G.1
Hwang, K.K.2
Pandita, R.K.3
-
46
-
-
0037427086
-
hTERT associates with human telomeres and enhances genomic stability and DNA repair
-
Sharma GG, Gupta A, Wang H, et al. hTERT associates with human telomeres and enhances genomic stability and DNA repair. Oncogene 2003; 22:131-146.
-
(2003)
Oncogene
, vol.22
, pp. 131-146
-
-
Sharma, G.G.1
Gupta, A.2
Wang, H.3
-
47
-
-
20444371017
-
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
-
Masutomi K, Possemato R, Wong JM, et al. The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc Natl Acad Sci USA 2005; 102:8222-8227.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8222-8227
-
-
Masutomi, K.1
Possemato, R.2
Wong, J.M.3
-
48
-
-
1842478446
-
Introduction of human telomerase reverse transcriptase to normal human fibroblasts enhances DNA repair capacity
-
Shin KH, Kang MK, Dicterow E, Kameta A, Baluda MA, Park NH. Introduction of human telomerase reverse transcriptase to normal human fibroblasts enhances DNA repair capacity. Clin Cancer Res 2004; 10:2551-2560.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2551-2560
-
-
Shin, K.H.1
Kang, M.K.2
Dicterow, E.3
Kameta, A.4
Baluda, M.A.5
Park, N.H.6
-
49
-
-
3242723326
-
Reconstitution of active telomerase in primary human foreskin fibroblasts: Effects on proliferative characteristics and response to ionizing radiation
-
Kampinga HH, Van Waarde-Verhagen MA, Van Assen-Bolt AJ, et al. Reconstitution of active telomerase in primary human foreskin fibroblasts: effects on proliferative characteristics and response to ionizing radiation. Int J Radiat Biol 2004; 80:377-388.
-
(2004)
Int J Radiat Biol
, vol.80
, pp. 377-388
-
-
Kampinga, H.H.1
Van Waarde-Verhagen, M.A.2
Van Assen-Bolt, A.J.3
-
50
-
-
18244390507
-
Repair of cyclobutane pyrimidine dimers or dimethylsulfate damage in DNA is identical in normal or telomerase-immortalized human skin fibroblasts
-
Bates SE, Zhou NY, Federico LE, Xia L, O'Connor TR. Repair of cyclobutane pyrimidine dimers or dimethylsulfate damage in DNA is identical in normal or telomerase-immortalized human skin fibroblasts. Nucleic Acids Res 2005; 33:2475-2485.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2475-2485
-
-
Bates, S.E.1
Zhou, N.Y.2
Federico, L.E.3
Xia, L.4
O'Connor, T.R.5
-
51
-
-
34248336270
-
P53-dependent integration of telomere and growth factor deprivation signals
-
Beliveau A, Bassett E, Lo AT. P53-dependent integration of telomere and growth factor deprivation signals. Proc Natl Acad Sci USA 2007; 104:4431-4436.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4431-4436
-
-
Beliveau, A.1
Bassett, E.2
Lo, A.T.3
-
52
-
-
34547676756
-
Soothing the watchman: Telomerase reduces the p53-dependent cellular stress response
-
Beliveau A. Soothing the watchman: Telomerase reduces the p53-dependent cellular stress response. Cell Cycle 2007; 6:1284-1287.
-
(2007)
Cell Cycle
, vol.6
, pp. 1284-1287
-
-
Beliveau, A.1
-
53
-
-
18644373013
-
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism
-
Stewart SA, Hahn WC, O'Connor BF, et al. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proc Natl Acad Sci USA 2002; 99:12606-12611.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12606-12611
-
-
Stewart, S.A.1
Hahn, W.C.2
O'Connor, B.F.3
-
54
-
-
23944516520
-
Conditional telomerase induction causes proliferation of hair follicle stem cells
-
Sarin KY, Cheung P, Gilison D, et al. Conditional telomerase induction causes proliferation of hair follicle stem cells. Nature 2005; 436:1048-1052.
-
(2005)
Nature
, vol.436
, pp. 1048-1052
-
-
Sarin, K.Y.1
Cheung, P.2
Gilison, D.3
-
55
-
-
23844540299
-
Effects of telomerase and telomere length on epidermal stem cell behavior
-
Flores I, Cayuela ML, Blasco MA. Effects of telomerase and telomere length on epidermal stem cell behavior. Science 2005; 309:1253-1256.
-
(2005)
Science
, vol.309
, pp. 1253-1256
-
-
Flores, I.1
Cayuela, M.L.2
Blasco, M.A.3
-
56
-
-
0036711651
-
Subnuclear shuttling of human telomerase induced by transformation and DNA damage
-
Wong JM, Kusdra L, Collins K. Subnuclear shuttling of human telomerase induced by transformation and DNA damage. Nat Cell Biol 2002; 4:731-736.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 731-736
-
-
Wong, J.M.1
Kusdra, L.2
Collins, K.3
-
57
-
-
0037148271
-
Telomerase in the human organism
-
Collins K, Mitchell JR. Telomerase in the human organism. Oncogene 2002; 21:564-579.
-
(2002)
Oncogene
, vol.21
, pp. 564-579
-
-
Collins, K.1
Mitchell, J.R.2
-
58
-
-
34548667973
-
Telomere length, stem cells and aging
-
Blasco MA. Telomere length, stem cells and aging. Nat Chem Biol 2007; 3:640-649.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 640-649
-
-
Blasco, M.A.1
-
59
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
Rudolph KL, Chang S, Lee HW, et al. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 1999; 96:701-712.
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
-
60
-
-
0035793907
-
Living with genome instability: Plant responses to telomere dysfunction
-
Riha K, McKnight TD, Griffing LR, Shippen DE. Living with genome instability: plant responses to telomere dysfunction. Science 2001; 291:1797-1800.
-
(2001)
Science
, vol.291
, pp. 1797-1800
-
-
Riha, K.1
McKnight, T.D.2
Griffing, L.R.3
Shippen, D.E.4
-
61
-
-
31544444692
-
High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans
-
Cheung I, Schertzer M, Rose A, Lansdorp PM. High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans. Nucleic Acids Res 2006; 34:96-103.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 96-103
-
-
Cheung, I.1
Schertzer, M.2
Rose, A.3
Lansdorp, P.M.4
-
62
-
-
38949156672
-
TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program
-
Epub Dec 13
-
Choi J, Southworth LK, Sarin KY, et al. TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program. PLoS Genet 2008; 4:e10. Epub 2007 Dec 13.
-
(2007)
PLoS Genet 2008
, vol.4
-
-
Choi, J.1
Southworth, L.K.2
Sarin, K.Y.3
-
63
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
64
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318:1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
65
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park IH, Zhao R, West JA, et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008; 451:141-146.
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
-
66
-
-
0038056347
-
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation
-
Smith LL, Coller HA, Roberts JM. Telomerase modulates expression of growth-controlling genes and enhances cell proliferation. Nat Cell Biol 2003; 5:474-479.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 474-479
-
-
Smith, L.L.1
Coller, H.A.2
Roberts, J.M.3
-
67
-
-
23944526322
-
Global gene expression response to telomerase in bovine adrenocortical cells
-
Perrault SD, Hornsby PT, Betts DH. Global gene expression response to telomerase in bovine adrenocortical cells. Biochem Biophys Res Commun 2005; 335:925-936.
-
(2005)
Biochem Biophys Res Commun
, vol.335
, pp. 925-936
-
-
Perrault, S.D.1
Hornsby, P.T.2
Betts, D.H.3
-
68
-
-
0344837729
-
Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: Activation of the Epiregulin gene
-
Lindvall C, Hou M, Komurasaki T, et al. Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the Epiregulin gene. Cancer Res 2003; 63:1743-1747.
-
(2003)
Cancer Res
, vol.63
, pp. 1743-1747
-
-
Lindvall, C.1
Hou, M.2
Komurasaki, T.3
-
69
-
-
33746591648
-
Genes and pathways downstream of telomerase in melanoma metastasis
-
Bagheri S, Nosrati M, Li S, et al. Genes and pathways downstream of telomerase in melanoma metastasis. Proc Natl Acad Sci USA 2006; 103:11306-11311.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11306-11311
-
-
Bagheri, S.1
Nosrati, M.2
Li, S.3
-
70
-
-
21244502260
-
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA
-
Li S, Crothers J, Haqq CM, Blackburn EH. Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA. J Biol Chem 2005; 280:23709-23717.
-
(2005)
J Biol Chem
, vol.280
, pp. 23709-23717
-
-
Li, S.1
Crothers, J.2
Haqq, C.M.3
Blackburn, E.H.4
-
71
-
-
33846631835
-
Up-regulation of Mac-2 binding protein by hTERT in gastric cancer
-
Park YP, Choi SC, Kim JH, et al. Up-regulation of Mac-2 binding protein by hTERT in gastric cancer. Int J Cancer 2007; 120:813-820.
-
(2007)
Int J Cancer
, vol.120
, pp. 813-820
-
-
Park, Y.P.1
Choi, S.C.2
Kim, J.H.3
-
72
-
-
33746190649
-
Telomerase reverse transcriptase regulates the expression of a key cell cycle regulator, cyclin D1
-
Jagadeesh S, Banerjee PP. Telomerase reverse transcriptase regulates the expression of a key cell cycle regulator, cyclin D1. Biochem Biophys Res Commu 2006; 347:774-780.
-
(2006)
Biochem Biophys Res Commu
, vol.347
, pp. 774-780
-
-
Jagadeesh, S.1
Banerjee, P.P.2
-
73
-
-
0038504020
-
Telomerase expression in normal human fibroblasts stabilizes DNA 5-methylcytosine transferase I
-
Yonng JI, Sedivy JM, Smith JR. Telomerase expression in normal human fibroblasts stabilizes DNA 5-methylcytosine transferase I. J Biol Chem 2003; 278:19904-19908.
-
(2003)
J Biol Chem
, vol.278
, pp. 19904-19908
-
-
Yonng, J.I.1
Sedivy, J.M.2
Smith, J.R.3
-
74
-
-
0037207872
-
Nuclear Factor-κB p65 mediates tumor necrosis factor α-induced nuclear translocation of telomerase reverse transcriptase protein
-
Akiyama M, Hideshima T, Hayashi T, et al. Nuclear Factor-κB p65 mediates tumor necrosis factor α-induced nuclear translocation of telomerase reverse transcriptase protein. Cancer Res 2003; 63:18-21.
-
(2003)
Cancer Res
, vol.63
, pp. 18-21
-
-
Akiyama, M.1
Hideshima, T.2
Hayashi, T.3
-
75
-
-
2642610318
-
Myc activates telomerase
-
Wang J, Xie LY, Allan S, Beach D, Hannon GJ. Myc activates telomerase. Genes Dev 1998; 12:1769-1774.
-
(1998)
Genes Dev
, vol.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
Beach, D.4
Hannon, G.J.5
-
76
-
-
0034660513
-
Risky immortalization by telomerase
-
Wang J, Hannon GJ, Heach DH. Risky immortalization by telomerase. Nature 2000; 405:755-756.
-
(2000)
Nature
, vol.405
, pp. 755-756
-
-
Wang, J.1
Hannon, G.J.2
Heach, D.H.3
-
77
-
-
0037161961
-
Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway
-
Xiang H, Wang J, Mao Y, et al. Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway. Oncogene 2002; 21:3784-3791.
-
(2002)
Oncogene
, vol.21
, pp. 3784-3791
-
-
Xiang, H.1
Wang, J.2
Mao, Y.3
-
78
-
-
33846014619
-
Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop
-
Lai SR, Cunningham AP, Huynh VQ, et al. Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop. Exp Cell Res 2007; 313:322-330.
-
(2007)
Exp Cell Res
, vol.313
, pp. 322-330
-
-
Lai, S.R.1
Cunningham, A.P.2
Huynh, V.Q.3
-
79
-
-
34047272162
-
The telomerase reverse transcriptase (hTERT) gene is direct target of histone methyltransferase SMYD3
-
Liu C, Fang X, Ge Z, et al. The telomerase reverse transcriptase (hTERT) gene is direct target of histone methyltransferase SMYD3. Cancer Res 2007; 67:2626-2631.
-
(2007)
Cancer Res
, vol.67
, pp. 2626-2631
-
-
Liu, C.1
Fang, X.2
Ge, Z.3
|