BRACO19 analog dimers with improved inhibition of telomerase and hPot 1

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 5, 2009, Pages 2030-2037

  Fu, Yuan Te ^a   Keppler, Brian R ^a   Soares, Joana ^a   Jarstfer, Michael B ^a  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

Author keywords

Acridines; G Quadruplex; hPot1; Telomerase; Telomere

Indexed keywords

ACRIDINE DERIVATIVE; BAD1 DERIVATIVE; BAD2 DERIVATIVE; BAD3 DERIVATIVE; BRACO 19; BRACO 19 ANALOG DIMER; BRACO 19 ANALOG DIMER DERIVATIVE; BRACO 19 ANALOG DIMER LIGAND; DIACRIDINE DERIVATIVE; DIMER; DOUBLE STRANDED DNA; GUANINE QUADRUPLEX; HUMAN PROTECTION OF TELOMERES 1 PROTEIN; LIGAND; OLIGONUCLEOTIDE; SINGLE STRANDED OLIGONUCLEOTIDE; TELOMERASE INHIBITOR; TELOMERE BINDING PROTEIN; TELOMESTATIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DNA BINDING; ENZYME INHIBITION; HUMAN; IC 50; PROTON NUCLEAR MAGNETIC RESONANCE; STOICHIOMETRY; TELOMERE;

ACRIDINES; CIRCULAR DICHROISM; DIMERIZATION; G-QUADRUPLEXES; HUMANS; INHIBITORY CONCENTRATION 50; TELOMERASE; TELOMERE; TELOMERE-BINDING PROTEINS;

EID: 61349096133     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.01.015     Document Type: Article

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