메뉴 건너뛰기




Volumn 42, Issue 3, 2011, Pages 308-318

Human Telomerase Domain Interactions Capture DNA for TEN Domain-Dependent Processive Elongation

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE;

EID: 79955492603     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2011.03.012     Document Type: Article
Times cited : (68)

References (47)
  • 1
    • 0034775749 scopus 로고    scopus 로고
    • N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo
    • Armbruster B.N., Banik S.S.R., Guo C., Smith A.C., Counter C.M. N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo. Mol. Cell. Biol. 2001, 22:7775-7786.
    • (2001) Mol. Cell. Biol. , vol.22 , pp. 7775-7786
    • Armbruster, B.N.1    Banik, S.S.R.2    Guo, C.3    Smith, A.C.4    Counter, C.M.5
  • 2
    • 0033790120 scopus 로고    scopus 로고
    • Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding
    • Beattie T.L., Zhou W., Robinson M.O., Harrington L. Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding. Mol. Biol. Cell 2000, 11:3329-3340.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 3329-3340
    • Beattie, T.L.1    Zhou, W.2    Robinson, M.O.3    Harrington, L.4
  • 3
    • 0035723994 scopus 로고    scopus 로고
    • Functional multimerization of the human telomerase reverse transcriptase
    • Beattie T.L., Zhou W., Robinson M.O., Harrington L. Functional multimerization of the human telomerase reverse transcriptase. Mol. Cell. Biol. 2001, 21:6151-6160.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6151-6160
    • Beattie, T.L.1    Zhou, W.2    Robinson, M.O.3    Harrington, L.4
  • 5
    • 0037148270 scopus 로고    scopus 로고
    • New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin
    • Chan S.W., Blackburn E.H. New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin. Oncogene 2002, 21:553-563.
    • (2002) Oncogene , vol.21 , pp. 553-563
    • Chan, S.W.1    Blackburn, E.H.2
  • 6
    • 0344011566 scopus 로고    scopus 로고
    • Template boundary definition in mammalian telomerase
    • Chen J.L., Greider C.W. Template boundary definition in mammalian telomerase. Genes Dev. 2003, 17:2747-2752.
    • (2003) Genes Dev. , vol.17 , pp. 2747-2752
    • Chen, J.L.1    Greider, C.W.2
  • 7
    • 6944256804 scopus 로고    scopus 로고
    • An emerging consensus for telomerase RNA structure
    • Chen J.L., Greider C.W. An emerging consensus for telomerase RNA structure. Proc. Natl. Acad. Sci. USA 2004, 101:14683-14684.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 14683-14684
    • Chen, J.L.1    Greider, C.W.2
  • 8
    • 0037079673 scopus 로고    scopus 로고
    • A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA
    • Chen J.L., Opperman K.K., Greider C.W. A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA. Nucleic Acids Res. 2002, 30:592-597.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 592-597
    • Chen, J.L.1    Opperman, K.K.2    Greider, C.W.3
  • 9
    • 0032834328 scopus 로고    scopus 로고
    • Ciliate telomerase biochemistry
    • Collins K. Ciliate telomerase biochemistry. Annu. Rev. Biochem. 1999, 68:187-218.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 187-218
    • Collins, K.1
  • 10
    • 38849191137 scopus 로고    scopus 로고
    • Physiological assembly and activity of human telomerase complexes
    • Collins K. Physiological assembly and activity of human telomerase complexes. Mech. Ageing Dev. 2008, 129:91-98.
    • (2008) Mech. Ageing Dev. , vol.129 , pp. 91-98
    • Collins, K.1
  • 11
    • 70449682033 scopus 로고    scopus 로고
    • Forms and functions of telomerase RNA
    • Springer-Verlag, Berlin, N.G. Walter, S.A. Woodson, R.T. Batey (Eds.)
    • Collins K. Forms and functions of telomerase RNA. Non-Protein Coding RNAs 2009, 285-301. Springer-Verlag, Berlin. N.G. Walter, S.A. Woodson, R.T. Batey (Eds.).
    • (2009) Non-Protein Coding RNAs , pp. 285-301
    • Collins, K.1
  • 14
    • 77952604818 scopus 로고    scopus 로고
    • Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo
    • Egan E.D., Collins K. Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo. Mol. Cell. Biol. 2010, 30:2775-2786.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 2775-2786
    • Egan, E.D.1    Collins, K.2
  • 15
    • 53549114805 scopus 로고    scopus 로고
    • Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference
    • Errington T.M., Fu D., Wong J.M., Collins K. Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference. Mol. Cell. Biol. 2008, 28:6510-6520.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 6510-6520
    • Errington, T.M.1    Fu, D.2    Wong, J.M.3    Collins, K.4
  • 16
    • 36749010238 scopus 로고    scopus 로고
    • Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation
    • Fu D., Collins K. Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation. Mol. Cell 2007, 28:773-785.
    • (2007) Mol. Cell , vol.28 , pp. 773-785
    • Fu, D.1    Collins, K.2
  • 17
    • 53349161932 scopus 로고    scopus 로고
    • Structure of the Tribolium castaneum telomerase catalytic subunit TERT
    • Gillis A.J., Schuller A.P., Skordalakes E. Structure of the Tribolium castaneum telomerase catalytic subunit TERT. Nature 2008, 455:633-637.
    • (2008) Nature , vol.455 , pp. 633-637
    • Gillis, A.J.1    Schuller, A.P.2    Skordalakes, E.3
  • 19
    • 33644800744 scopus 로고    scopus 로고
    • Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase
    • Jacobs S.A., Podell E.R., Cech T.R. Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase. Nat. Struct. Mol. Biol. 2006, 13:218-225.
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 218-225
    • Jacobs, S.A.1    Podell, E.R.2    Cech, T.R.3
  • 21
    • 33746030307 scopus 로고    scopus 로고
    • The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity
    • Keppler B.R., Grady A.T., Jarstfer M.B. The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity. J. Biol. Chem. 2006, 281:19840-19848.
    • (2006) J. Biol. Chem. , vol.281 , pp. 19840-19848
    • Keppler, B.R.1    Grady, A.T.2    Jarstfer, M.B.3
  • 22
    • 0027140403 scopus 로고
    • New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats
    • Kramer K.M., Haber J.E. New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats. Genes Dev. 1993, 7:2345-2356.
    • (1993) Genes Dev. , vol.7 , pp. 2345-2356
    • Kramer, K.M.1    Haber, J.E.2
  • 23
    • 0035144580 scopus 로고    scopus 로고
    • RNA binding domain of telomerase reverse transcriptase
    • Lai C.K., Mitchell J.R., Collins K. RNA binding domain of telomerase reverse transcriptase. Mol. Cell. Biol. 2001, 21:990-1000.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 990-1000
    • Lai, C.K.1    Mitchell, J.R.2    Collins, K.3
  • 24
    • 0037083759 scopus 로고    scopus 로고
    • Template boundary definition in Tetrahymena telomerase
    • Lai C.K., Miller M.C., Collins K. Template boundary definition in Tetrahymena telomerase. Genes Dev. 2002, 16:415-420.
    • (2002) Genes Dev. , vol.16 , pp. 415-420
    • Lai, C.K.1    Miller, M.C.2    Collins, K.3
  • 25
    • 22544441637 scopus 로고    scopus 로고
    • A physical and functional constituent of telomerase anchor site
    • Lue N.F. A physical and functional constituent of telomerase anchor site. J. Biol. Chem. 2005, 280:26586-26591.
    • (2005) J. Biol. Chem. , vol.280 , pp. 26586-26591
    • Lue, N.F.1
  • 26
    • 0037076276 scopus 로고    scopus 로고
    • Telomerase recognizes its template by using an adjacent RNA motif
    • Miller M.C., Collins K. Telomerase recognizes its template by using an adjacent RNA motif. Proc. Natl. Acad. Sci. USA 2002, 99:6585-6590.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6585-6590
    • Miller, M.C.1    Collins, K.2
  • 27
    • 70449641058 scopus 로고    scopus 로고
    • An RPA-related sequence-specific DNA-binding subunit of telomerase holoenzyme is required for elongation processivity and telomere maintenance
    • Min B., Collins K. An RPA-related sequence-specific DNA-binding subunit of telomerase holoenzyme is required for elongation processivity and telomere maintenance. Mol. Cell 2009, 36:609-619.
    • (2009) Mol. Cell , vol.36 , pp. 609-619
    • Min, B.1    Collins, K.2
  • 28
    • 0033636897 scopus 로고    scopus 로고
    • Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase in vivo and in vitro
    • Mitchell J.R., Collins K. Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase in vivo and in vitro. Mol. Cell 2000, 6:361-371.
    • (2000) Mol. Cell , vol.6 , pp. 361-371
    • Mitchell, J.R.1    Collins, K.2
  • 29
    • 77950471767 scopus 로고    scopus 로고
    • Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA
    • Mitchell M., Gillis A., Futahashi M., Fujiwara H., Skordalakes E. Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. Nat. Struct. Mol. Biol. 2010, 17:513-518.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 513-518
    • Mitchell, M.1    Gillis, A.2    Futahashi, M.3    Fujiwara, H.4    Skordalakes, E.5
  • 31
    • 1942453903 scopus 로고    scopus 로고
    • Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer
    • Moriarty T.J., Marie-Egyptienne D.T., Autexier C. Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer. Mol. Cell. Biol. 2004, 24:3720-3733.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 3720-3733
    • Moriarty, T.J.1    Marie-Egyptienne, D.T.2    Autexier, C.3
  • 32
    • 21844457135 scopus 로고    scopus 로고
    • An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization
    • Moriarty T.J., Ward R.J., Taboski M.A., Autexier C. An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization. Mol. Biol. Cell 2005, 16:3152-3161.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 3152-3161
    • Moriarty, T.J.1    Ward, R.J.2    Taboski, M.A.3    Autexier, C.4
  • 33
    • 20444481334 scopus 로고    scopus 로고
    • Two purified domains of telomerase reverse transcriptase reconstitute sequence-specific interactions with RNA
    • O'Connor C.M., Lai C.K., Collins K. Two purified domains of telomerase reverse transcriptase reconstitute sequence-specific interactions with RNA. J. Biol. Chem. 2005, 280:17533-17539.
    • (2005) J. Biol. Chem. , vol.280 , pp. 17533-17539
    • O'Connor, C.M.1    Lai, C.K.2    Collins, K.3
  • 34
    • 77649180958 scopus 로고    scopus 로고
    • Telomeres: protecting chromosomes against genome instability
    • O'Sullivan R.J., Karlseder J. Telomeres: protecting chromosomes against genome instability. Nat. Rev. Mol. Cell Biol. 2010, 11:171-181.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 171-181
    • O'Sullivan, R.J.1    Karlseder, J.2
  • 36
    • 77951178977 scopus 로고    scopus 로고
    • Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants
    • Robart A.R., Collins K. Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants. J. Biol. Chem. 2010, 285:4375-4386.
    • (2010) J. Biol. Chem. , vol.285 , pp. 4375-4386
    • Robart, A.R.1    Collins, K.2
  • 37
    • 34547433779 scopus 로고    scopus 로고
    • High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase
    • Romi E., Baran N., Gantman M., Shmoish M., Min B., Collins K., Manor H. High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase. Proc. Natl. Acad. Sci. USA 2007, 104:8791-8796.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 8791-8796
    • Romi, E.1    Baran, N.2    Gantman, M.3    Shmoish, M.4    Min, B.5    Collins, K.6    Manor, H.7
  • 38
    • 35748951600 scopus 로고    scopus 로고
    • Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding
    • Rouda S., Skordalakes E. Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding. Structure 2007, 13:1403-1412.
    • (2007) Structure , vol.13 , pp. 1403-1412
    • Rouda, S.1    Skordalakes, E.2
  • 39
    • 77951237385 scopus 로고    scopus 로고
    • The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization
    • Sealey D.C., Zheng L., Taboski M.A., Cruickshank J., Ikura M., Harrington L.A. The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization. Nucleic Acids Res. 2010, 38:2019-2035.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 2019-2035
    • Sealey, D.C.1    Zheng, L.2    Taboski, M.A.3    Cruickshank, J.4    Ikura, M.5    Harrington, L.A.6
  • 40
    • 77949570427 scopus 로고    scopus 로고
    • Structures of telomerase subunits provide functional insights
    • Sekaran V.G., Soares J., Jarstfer M.B. Structures of telomerase subunits provide functional insights. Biochim. Biophys. Acta 2010, 1804:1190-1201.
    • (2010) Biochim. Biophys. Acta , vol.1804 , pp. 1190-1201
    • Sekaran, V.G.1    Soares, J.2    Jarstfer, M.B.3
  • 41
    • 0027944347 scopus 로고
    • TLC1: template RNA component of Saccharomyces cerevisiae telomerase
    • Singer M.S., Gottschling D.E. TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 1994, 266:404-409.
    • (1994) Science , vol.266 , pp. 404-409
    • Singer, M.S.1    Gottschling, D.E.2
  • 42
    • 33947494652 scopus 로고    scopus 로고
    • Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein
    • Stone M.S., Mihalusova M., O'Connor C.M., Prathapam R., Collins K., Zhuang X. Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein. Nature 2007, 446:458-461.
    • (2007) Nature , vol.446 , pp. 458-461
    • Stone, M.S.1    Mihalusova, M.2    O'Connor, C.M.3    Prathapam, R.4    Collins, K.5    Zhuang, X.6
  • 43
    • 0034608073 scopus 로고    scopus 로고
    • Template boundary in a yeast telomerase specified by RNA structure
    • Tzfati Y., Fulton T.B., Roy J., Blackburn E.H. Template boundary in a yeast telomerase specified by RNA structure. Science 2000, 288:863-867.
    • (2000) Science , vol.288 , pp. 863-867
    • Tzfati, Y.1    Fulton, T.B.2    Roy, J.3    Blackburn, E.H.4
  • 44
    • 0032481419 scopus 로고    scopus 로고
    • A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase
    • Wang H., Gilley D., Blackburn E.H. A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase. EMBO J. 1998, 17:1152-1160.
    • (1998) EMBO J. , vol.17 , pp. 1152-1160
    • Wang, H.1    Gilley, D.2    Blackburn, E.H.3
  • 45
    • 33846691378 scopus 로고    scopus 로고
    • The POT1-TPP1 telomere complex is a telomerase processivity factor
    • Wang F., Podell E.R., Zaug A.J., Yang Y., Baciu P., Cech T.R., Lei M. The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature 2007, 445:506-510.
    • (2007) Nature , vol.445 , pp. 506-510
    • Wang, F.1    Podell, E.R.2    Zaug, A.J.3    Yang, Y.4    Baciu, P.5    Cech, T.R.6    Lei, M.7
  • 46
    • 77957220075 scopus 로고    scopus 로고
    • InTERTpreting telomerase structure and function
    • Wyatt H.D., West S.C., Beattie T.L. InTERTpreting telomerase structure and function. Nucleic Acids Res. 2010, 38:5609-5622.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 5609-5622
    • Wyatt, H.D.1    West, S.C.2    Beattie, T.L.3
  • 47
    • 78650452333 scopus 로고    scopus 로고
    • Inaugural article: structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA
    • Zhang Q., Kim N.K., Peterson R.D., Wang Z., Feigon J. Inaugural article: structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA. Proc. Natl. Acad. Sci. USA 2010, 107:18761-18768.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 18761-18768
    • Zhang, Q.1    Kim, N.K.2    Peterson, R.D.3    Wang, Z.4    Feigon, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.