The ability of polycyclic aromatic hydrocarbons to alter physiological factors underlying drug disposition

Drug Metabolism Reviews

Volumn 43, Issue 4, 2011, Pages 457-475

  Elsherbiny, Marwa E ^a   Brocks, Dion R ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Charcoal broiled; CYP1A; Drug metabolism; Enzyme induction; Pharmacokinetics; Polycyclic aromatic hydrocarbons; Tobacco smoke

Indexed keywords

3 HYDROXYMETHYLPHENAZONE; 3 METHYLCHOLANTHRENE; BENZO[A]PYRENE; BETA NAPHTHOFLAVONE; CAFFEINE; CARRIER PROTEIN; CHRYSENE; CYTOCHROME P450 1A; CYTOCHROME P450 1B1; CYTOCHROME P450 2E1; ERLOTINIB; FLUORANTHENE; IRINOTECAN; LIPOPROTEIN; NAPHTHALENE; NORDAZEPAM; OLANZAPINE; OROSOMUCOID; PHENACETIN; PHENANTHRENE; PHENAZONE; POLYCYCLIC AROMATIC HYDROCARBON; PROPRANOLOL; PYRENE; QUINIDINE; QUININE; ROPIVACAINE; THEOPHYLLINE; TIOTIXENE; UNINDEXED DRUG;

DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG HALF LIFE; DRUG METABOLISM; DRUG TISSUE LEVEL; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; LIVER WEIGHT; NONHUMAN; OCCUPATIONAL EXPOSURE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REVIEW; RISK REDUCTION; SMOKING;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 CYP1A1; DRUG INTERACTIONS; ENVIRONMENTAL POLLUTANTS; ENZYME INDUCTION; HUMANS; LIVER; MEMBRANE TRANSPORT PROTEINS; POLYCYCLIC HYDROCARBONS, AROMATIC; RISK ASSESSMENT; SUBSTRATE SPECIFICITY;

EID: 80054920309     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602532.2011.596204     Document Type: Review

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