Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double- null mice

Toxicology and Applied Pharmacology

Volumn 152, Issue 1, 1998, Pages 193-199

  Zaher, Hani ^a   Buters, Jeroen T M ^a,d   Ward, Jerrold M ^b   Bruno, Mary K ^c   Lucas, Angela M ^c   Stern, Stephan T ^c   Cohen, Steven D ^c   Gonzalez, Frank J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CYTOCHROME P450; DRUG METABOLITE; GLUTATHIONE; IDITOL DEHYDROGENASE; LIVER ENZYME; PARACETAMOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG INDUCED DISEASE; DRUG TRANSFORMATION; HISTOPATHOLOGY; KIDNEY TUBULE NECROSIS; LIPIDOSIS; LIVER MICROSOME; LIVER NECROSIS; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PHENOTYPE;

EID: 0031765730     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1998.8501     Document Type: Article

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