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Volumn 37, Issue 3, 1999, Pages 177-193

Olanzapine: Pharmacokinetic and pharmacodynamic profile

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ALCOHOL; AMINOPHYLLINE; BIPERIDEN; CARBAMAZEPINE; CYTOCHROME P450 ISOENZYME; DIAZEPAM; FLUOXETINE; FLUVOXAMINE; IMIPRAMINE; LITHIUM; NEUROLEPTIC AGENT; OLANZAPINE; OROSOMUCOID; PROLACTIN; TOBACCO SMOKE;

EID: 0032844187     PISSN: 03125963     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003088-199937030-00001     Document Type: Review
Times cited : (517)

References (56)
  • 1
    • 0000939940 scopus 로고
    • The pharmacology of olanzapine, and other new antipsychotic agents
    • Moore NA, Calligaro DO, Wong DT, et al. The pharmacology of olanzapine, and other new antipsychotic agents. Curr Opin Invest Drugs 1993; 2: 281-93
    • (1993) Curr Opin Invest Drugs , vol.2 , pp. 281-293
    • Moore, N.A.1    Calligaro, D.O.2    Wong, D.T.3
  • 2
    • 0003100133 scopus 로고
    • What makes a neuroleptic atypical?
    • Meltzer HY, editor. New York: Raven
    • Casey DE. What makes a neuroleptic atypical? In: Meltzer HY, editor. Novel antipsychotic drugs. New York: Raven, 1992: 241-51
    • (1992) Novel Antipsychotic Drugs , pp. 241-251
    • Casey, D.E.1
  • 3
    • 0003088549 scopus 로고
    • The mechanism of action of clozapine in relation to its clinical advantages
    • Meltzer HY, editor. New York: Raven
    • Meltzer HY. The mechanism of action of clozapine in relation to its clinical advantages. In: Meltzer HY, editor. Novel antipsychotic drugs. New York: Raven, 1992: 1-13
    • (1992) Novel Antipsychotic Drugs , pp. 1-13
    • Meltzer, H.Y.1
  • 4
    • 0026651080 scopus 로고
    • Neuroendocrine evidence for antagonism of serotonin and dopamine receptors by olanzapine (LY 170053) an antipsychotic drug candidate
    • Fuller A, Snoddy HD. Neuroendocrine evidence for antagonism of serotonin and dopamine receptors by olanzapine (LY 170053) an antipsychotic drug candidate. Res Commun Chem Pathol Pharmacol 1992; 77 (1): 87-93
    • (1992) Res Commun Chem Pathol Pharmacol , vol.77 , Issue.1 , pp. 87-93
    • Fuller, A.1    Snoddy, H.D.2
  • 5
    • 0030062260 scopus 로고    scopus 로고
    • Radioreceptor binding profile of the atypical antipsychotic olanzapine
    • Bymaster FP, Calligaro DO, Falcone JF, et al. Radioreceptor binding profile of the atypical antipsychotic olanzapine. Neuropsychopharmacology 1996; 14 (2): 87-96
    • (1996) Neuropsychopharmacology , vol.14 , Issue.2 , pp. 87-96
    • Bymaster, F.P.1    Calligaro, D.O.2    Falcone, J.F.3
  • 6
    • 0029030343 scopus 로고
    • Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors
    • Corbett R, Camacho F, Woods AT, et al. Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors. Psychopharmacology (Berl) 1995; 120: 67-74
    • (1995) Psychopharmacology (Berl) , vol.120 , pp. 67-74
    • Corbett, R.1    Camacho, F.2    Woods, A.T.3
  • 7
    • 0002386214 scopus 로고    scopus 로고
    • Efficacy of olanzapine: An overview of pivotal clinical trials
    • Beasley CM. Efficacy of olanzapine: an overview of pivotal clinical trials. J Clin Psychiatry Monogr 1997; 15: 16-8
    • (1997) J Clin Psychiatry Monogr , vol.15 , pp. 16-18
    • Beasley, C.M.1
  • 8
    • 0030880365 scopus 로고    scopus 로고
    • Blind, controlled, long-term study of the comparative incidence of treatment-emergent tardive dyskinesia with olanzapine or haloperidol
    • Tollefson GD, Beasley CM, Tamura RN, et al. Blind, controlled, long-term study of the comparative incidence of treatment-emergent tardive dyskinesia with olanzapine or haloperidol. Am J Psychiatry 1997; 154(9): 1248-54
    • (1997) Am J Psychiatry , vol.154 , Issue.9 , pp. 1248-1254
    • Tollefson, G.D.1    Beasley, C.M.2    Tamura, R.N.3
  • 10
    • 0001345614 scopus 로고
    • Pharmacokinetics of olanzapine in elderly and young
    • Bergstrom RF, Callaghan JT, Cerimele BJ, et al. Pharmacokinetics of olanzapine in elderly and young. Pharm Res 1995; 12 Suppl. 9: S-358
    • (1995) Pharm Res , vol.12 , Issue.SUPPL. 9
    • Bergstrom, R.F.1    Callaghan, J.T.2    Cerimele, B.J.3
  • 11
    • 0009702991 scopus 로고
    • Olanzapine: An initial assessment of the bioequivalence of capsules and tablet formulations
    • American Association of Pharmaceutical Scientists; Nov 5-9; Miami Beach (FL)
    • Nyhart Jr EH, Cerimele BJ, Kassahun K, et al. Olanzapine: an initial assessment of the bioequivalence of capsules and tablet formulations [abstract no. 8355]. 10th Annual Meeting and Exposition, American Association of Pharmaceutical Scientists; 1995 Nov 5-9; Miami Beach (FL)
    • (1995) 10th Annual Meeting and Exposition
    • Nyhart E.H., Jr.1    Cerimele, B.J.2    Kassahun, K.3
  • 12
    • 0009671356 scopus 로고    scopus 로고
    • Olazapine in subjects with and without renal failure
    • Eli Lilly und Co., (Data on file)
    • Bergstrom RF, Cerimele BJ, et al. Olazapine in subjects with and without renal failure. Lilly Laboratory for Clinical Research. Eli Lilly und Co., 1996. (Data on file)
    • (1996) Lilly Laboratory for Clinical Research
    • Bergstrom, R.F.1    Cerimele, B.J.2
  • 14
    • 0009747805 scopus 로고    scopus 로고
    • Oral olanzapine: Safety and pharmacokineticstudy in subjects with cirrhosis
    • Eli Lilly and Co., (Data on file)
    • Thomasson HR, Callaghan JT, Bergstrom RF, et al. Oral olanzapine: safety and pharmacokineticstudy in subjects with cirrhosis. Lilly Laboratory for Clinical Research. Eli Lilly and Co., 1996. (Data on file)
    • (1996) Lilly Laboratory for Clinical Research
    • Thomasson, H.R.1    Callaghan, J.T.2    Bergstrom, R.F.3
  • 16
    • 0009736565 scopus 로고
    • LY 170 053: Dose proportionality and effect of feeding on bioavailability
    • Eli Lilly and Co., (Data on file)
    • Henry DP, Nybart Jr EH. LY 170 053: dose proportionality and effect of feeding on bioavailability. Lilly Laboratory for Clinical Research. Eli Lilly and Co., 1995. (Data on file)
    • (1995) Lilly Laboratory for Clinical Research
    • Henry, D.P.1    Nybart E.H., Jr.2
  • 18
    • 0009667380 scopus 로고    scopus 로고
    • Olanzapine: Safety and pharmacokinetic studies on patients with cirrhosis - Olanzapine excretion addendum
    • Eli Lilly and Co., (Data on file)
    • Malituz EL, Cerimele BJ, Ptak L. Olanzapine: safety and pharmacokinetic studies on patients with cirrhosis - olanzapine excretion addendum. Lilly Laboratory for Clinical Research. Eli Lilly and Co., 1997. (Data on file)
    • (1997) Lilly Laboratory for Clinical Research
    • Malituz, E.L.1    Cerimele, B.J.2    Ptak, L.3
  • 19
    • 0031030609 scopus 로고    scopus 로고
    • Disposition and biotransformation of the antipsychotic agent olanzapine in humans
    • Kassahun K, Mattiuz E, Nyhart Jr E, et al. Disposition and biotransformation of the antipsychotic agent olanzapine in humans. Drug Metab Dispos 1997; 25 (1): 81-93
    • (1997) Drug Metab Dispos , vol.25 , Issue.1 , pp. 81-93
    • Kassahun, K.1    Mattiuz, E.2    Nyhart E., Jr.3
  • 20
    • 0030077735 scopus 로고    scopus 로고
    • Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine
    • Ring BJ, Catlow J, Lindsay TJ, et al. Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther 1996; 276: 658-66
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 658-666
    • Ring, B.J.1    Catlow, J.2    Lindsay, T.J.3
  • 23
    • 0029983702 scopus 로고
    • In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A
    • Ring BJ, Binkley SN, Vandenbranden M, et al. In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A. Br J Clin Pharmacol 1906; 41: 181-6
    • (1906) Br J Clin Pharmacol , vol.41 , pp. 181-186
    • Ring, B.J.1    Binkley, S.N.2    Vandenbranden, M.3
  • 26
    • 0031757721 scopus 로고    scopus 로고
    • Lack of an effect of olanzapine on the pharmacokinetics of a single aminophylline dose in healthy men
    • Macias WL, Bergstrom RF, Cerimele BJ, et al. Lack of an effect of olanzapine on the pharmacokinetics of a single aminophylline dose in healthy men. Pharmacotherapy 1998; 18 (6): 1237-48
    • (1998) Pharmacotherapy , vol.18 , Issue.6 , pp. 1237-1248
    • Macias, W.L.1    Bergstrom, R.F.2    Cerimele, B.J.3
  • 27
    • 0001440282 scopus 로고
    • Interaction between olanzapine and lithium in healthy male volunteers
    • Demmole D, Onkelinx C, Muller-Oerlinghausen B. Interaction between olanzapine and lithium in healthy male volunteers [abstract]. Therapie 1995; 50 Suppl.: 486
    • (1995) Therapie , vol.50 , Issue.SUPPL. , pp. 486
    • Demmole, D.1    Onkelinx, C.2    Muller-Oerlinghausen, B.3
  • 29
    • 0027406654 scopus 로고
    • Fluvoxamine is a potent inhibitor of cytochrome P4501A2
    • Brosen K, Skjelbo E, Rasmussen BB, et al. Fluvoxamine is a potent inhibitor of cytochrome P4501A2. Biochem Pharmacol 1993; 45 (6): 1211-4
    • (1993) Biochem Pharmacol , vol.45 , Issue.6 , pp. 1211-1214
    • Brosen, K.1    Skjelbo, E.2    Rasmussen, B.B.3
  • 30
    • 0028898044 scopus 로고
    • Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: Potent inhibition by fluvoxamine
    • Rasmussen BB, Maenpaa J, Pelkonen O, et al. Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine. Br J Clin Pharmacol 1995; 39 (2); 151-9
    • (1995) Br J Clin Pharmacol , vol.39 , Issue.2 , pp. 151-159
    • Rasmussen, B.B.1    Maenpaa, J.2    Pelkonen, O.3
  • 31
    • 14444283041 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic interactions between fluvoxamine and olanzapine
    • MäenpääJ, Wrighton S, Bergstrom R, Bergstrom R, et al. Pharmacokinetic and pharmacodynamic interactions between fluvoxamine and olanzapine [abstract]. Clin Pharmacol Ther 1997; 61 (2): 225
    • (1997) Clin Pharmacol Ther , vol.61 , Issue.2 , pp. 225
    • Mäenpää, J.1    Wrighton, S.2    Bergstrom, R.3    Bergstrom, R.4
  • 32
    • 0020446078 scopus 로고
    • Microsomal enzyme induction in children: The influence of carbamazepine treatment on antipyrine kinetics, 6-beta-hydroxycortisol excretion and plasma gamma-glutamyltransferase activity
    • Moreland TA, Park BK, Rylance GW. Microsomal enzyme induction in children: the influence of carbamazepine treatment on antipyrine kinetics, 6-beta-hydroxycortisol excretion and plasma gamma-glutamyltransferase activity. Br J Clin Pharmacol 1982; 14 (6): 861-5
    • (1982) Br J Clin Pharmacol , vol.14 , Issue.6 , pp. 861-865
    • Moreland, T.A.1    Park, B.K.2    Rylance, G.W.3
  • 33
    • 0027428427 scopus 로고
    • Anticpileptic drugs: A review of clinically significant drug interactions
    • Patsalos PN, Duncan JS. Anticpileptic drugs: a review of clinically significant drug interactions. Drug Saf 1993; 9 (3): 156-84
    • (1993) Drug Saf , vol.9 , Issue.3 , pp. 156-184
    • Patsalos, P.N.1    Duncan, J.S.2
  • 34
    • 0031594230 scopus 로고    scopus 로고
    • Induction of CYP1A2 activity by carbamazepine in children using the caffeine breath test
    • Choonara I, Parker AC, Preston T, et al. Induction of CYP1A2 activity by carbamazepine in children using the caffeine breath test. Br J Clin Pharmacol 1998; 45 (2): 176-8
    • (1998) Br J Clin Pharmacol , vol.45 , Issue.2 , pp. 176-178
    • Choonara, I.1    Parker, A.C.2    Preston, T.3
  • 35
    • 0031770968 scopus 로고    scopus 로고
    • A pharmacokinetic interaction between carbamazepine and olanzapine: Observations on possible mechanisms
    • Oct
    • Lucas RA, Gilfillan DJ, Bergstrom RF. A pharmacokinetic interaction between carbamazepine and olanzapine: observations on possible mechanisms. Eur J Clin Pharmacol 1998 Oct; 54 (8): 639-43
    • (1998) Eur J Clin Pharmacol , vol.54 , Issue.8 , pp. 639-643
    • Lucas, R.A.1    Gilfillan, D.J.2    Bergstrom, R.F.3
  • 36
    • 0021289398 scopus 로고
    • Human cylochromes P-450
    • Boobis AR, Davies DS. Human cylochromes P-450. Xenobiotica 1984; 14 (1-2): 151-85
    • (1984) Xenobiotica , vol.14 , Issue.1-2 , pp. 151-185
    • Boobis, A.R.1    Davies, D.S.2
  • 37
    • 0025969276 scopus 로고
    • Caffeine as a metabolite probe: Exploration of the enzyme-inducing effect of cigarette smoking
    • Kalow W, Tang BK. Caffeine as a metabolite probe: exploration of the enzyme-inducing effect of cigarette smoking. Clin Pharmacol Ther 1991; 49 (1): 44-8
    • (1991) Clin Pharmacol Ther , vol.49 , Issue.1 , pp. 44-48
    • Kalow, W.1    Tang, B.K.2
  • 38
    • 0023687412 scopus 로고
    • A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking
    • Sesardic D, Boobis AR, Edwards RJ, et al. A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking. Br J Clin Pharmacol 1988; 26 (4): 363-72
    • (1988) Br J Clin Pharmacol , vol.26 , Issue.4 , pp. 363-372
    • Sesardic, D.1    Boobis, A.R.2    Edwards, R.J.3
  • 42
    • 0031014718 scopus 로고    scopus 로고
    • A PET study of 5-HT2 and D2 dopamine receptor occupancy induced by olanzapine in healthy subjects
    • Nyberg S, Farde L, Halldin C. A PET study of 5-HT2 and D2 dopamine receptor occupancy induced by olanzapine in healthy subjects. Neuropsychopharmacology 1997; 16 (1): 1-7
    • (1997) Neuropsychopharmacology , vol.16 , Issue.1 , pp. 1-7
    • Nyberg, S.1    Farde, L.2    Halldin, C.3
  • 43
    • 0027341624 scopus 로고
    • 2 receptor occupancy in clozapine treated patients demonstrated by PET
    • 2 receptor occupancy in clozapine treated patients demonstrated by PET. Psychopharmacology 1993; 110: 365-7
    • (1993) Psychopharmacology , vol.110 , pp. 365-367
    • Nordstrom, A.-L.1    Farde, L.2    Halldin, C.3
  • 44
    • 0028991822 scopus 로고
    • 2 receptor occupancy in relation to clozapine serum concentration: A PET study of schizophrenic patients
    • 2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients. Am J Psychiatry 1995; 152 (10): 1444-9
    • (1995) Am J Psychiatry , vol.152 , Issue.10 , pp. 1444-1449
    • Nordstrom, A.-L.1    Farde, L.2    Nyberg, S.3
  • 45
    • 0030817163 scopus 로고    scopus 로고
    • The acute and long-term effect of olanzapine compared with placcbo and haloperidol on serum prolactin concentrations
    • Crawford AM, Beasley CM, Tollefson GD. The acute and long-term effect of olanzapine compared with placcbo and haloperidol on serum prolactin concentrations. Schizophrenia Res 1997; 26: 41-54
    • (1997) Schizophrenia Res , vol.26 , pp. 41-54
    • Crawford, A.M.1    Beasley, C.M.2    Tollefson, G.D.3
  • 46
    • 0030770872 scopus 로고    scopus 로고
    • Double-blind comparison of olanzapine versus risperidone in the treatment of schizophrenia and other psychotic disorders
    • Tran PV, Hamilton SH, Kuntz AJ, et al. Double-blind comparison of olanzapine versus risperidone in the treatment of schizophrenia and other psychotic disorders. J Clin Psychopharmacol 1997; 17 (5): 407-18
    • (1997) J Clin Psychopharmacol , vol.17 , Issue.5 , pp. 407-418
    • Tran, P.V.1    Hamilton, S.H.2    Kuntz, A.J.3
  • 47
    • 0030993030 scopus 로고    scopus 로고
    • Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: Results of an international collaborative trial
    • Tollefson GD, Beasley CM, Tran PV, et al. Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. Am J Psychiatry 1997; 154 (4): 457-65
    • (1997) Am J Psychiatry , vol.154 , Issue.4 , pp. 457-465
    • Tollefson, G.D.1    Beasley, C.M.2    Tran, P.V.3
  • 48
    • 0030065502 scopus 로고    scopus 로고
    • Olanzapine versus placebo and haloperidol: Acute phase results of the North American double-blind olanzapine trial
    • Beasley CM, Tollefson G, Tran P, et al. Olanzapine versus placebo and haloperidol: acute phase results of the North American double-blind olanzapine trial. Neuropsychopharmacology 1996; 14 (2): 111-23
    • (1996) Neuropsychopharmacology , vol.14 , Issue.2 , pp. 111-123
    • Beasley, C.M.1    Tollefson, G.2    Tran, P.3
  • 49
    • 0031905314 scopus 로고    scopus 로고
    • Olanzapine versus placebo and haloperidol: Quality of life and efficacy results of the North American double-blind trial
    • Hamilton SH, Revicki DA, Genduso LA, et al. Olanzapine versus placebo and haloperidol: quality of life and efficacy results of the North American double-blind trial. Neuropsychopharmacology 1998; 18 (1): 41-9
    • (1998) Neuropsychopharmacology , vol.18 , Issue.1 , pp. 41-49
    • Hamilton, S.H.1    Revicki, D.A.2    Genduso, L.A.3
  • 50
    • 1842404208 scopus 로고    scopus 로고
    • Olanzapine in treatment-refractory schizophrenia: Results of an open-label study
    • Martin J, Gomez JC, Garcia-Bernardo E, et al. Olanzapine in treatment-refractory schizophrenia: results of an open-label study. J Clin Psychiatry 1997; 58 (11): 479-83
    • (1997) J Clin Psychiatry , vol.58 , Issue.11 , pp. 479-483
    • Martin, J.1    Gomez, J.C.2    Garcia-Bernardo, E.3
  • 51
    • 0029930337 scopus 로고    scopus 로고
    • Olanzapine versus placebo: Results of a double-blind, fixed-dose olanzapine trial
    • Beasley Jr CM, Sanger T, Satterlee W, et al. Olanzapine versus placebo; results of a double-blind, fixed-dose olanzapine trial. Psychopharmacology 1996; 124: 159-67
    • (1996) Psychopharmacology , vol.124 , pp. 159-167
    • Beasley C.M., Jr.1    Sanger, T.2    Satterlee, W.3
  • 54
    • 0014723449 scopus 로고
    • A rating scale for extrapyramidal side effects
    • Simpson GM. Angus JW. A rating scale for extrapyramidal side effects. Acta Psychiatr Scand 1970; 212 Suppl.: 11-9
    • (1970) Acta Psychiatr Scand , vol.212 , Issue.SUPPL. , pp. 11-19
    • Simpson, G.M.1    Angus, J.W.2
  • 55
    • 0024358369 scopus 로고
    • A rating scale for drug-induced akathesia
    • Barnes TR. A rating scale for drug-induced akathesia. Br J Psychiatry 1989; 154: 672-6
    • (1989) Br J Psychiatry , vol.154 , pp. 672-676
    • Barnes, T.R.1


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