SCOPUS 정보 검색 플랫폼

Protein Purification: Principles, High Resolution Methods, and Applications: Third Edition

Volumn , Issue , 2011, Pages 339-362

Purification of PEGylated Proteins

(2) Fee, Conan J a Van Alstine, James M b

a UNIVERSITY OF CANTERBURY (New Zealand)

b GE Healthcare Bio Sciences AB (Sweden)

Author keywords

Ion exchange media, designed for PEG proteins with design considerations; PEGylated protein purification polymer modified pharmaceuticals, and growing family of pharmaceuticals; Selected separation methods, and separation on basis of molecular weight, size, and shape and separation on basis of solubility and hydrophobicity

Indexed keywords

ION EXCHANGE; PURIFICATION; SEPARATION;

DESIGN CONSIDERATIONS; PEGYLATED PROTEINS; POLYMER-MODIFIED; SEPARATION METHODS;

PROTEINS;

MACROGOL DERIVATIVE; PROTEIN;

ALGORITHM; CHEMICAL MODEL; CHEMISTRY; GEL CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METHODOLOGY; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVIEW; SOLUBILITY;

ALGORITHMS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MODELS, CHEMICAL; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; PROTEINS; SOLUBILITY;

EID: 80054826783 PISSN: None EISSN: None Source Type: Book
DOI: 10.1002/9780470939932.ch14 Document Type: Chapter

Times cited : (44)

References (99)

1
- 36549019051
- Issue Eds, Theme Issue on Peptide and Protein PEGylation III-Advances in Chemistry and Clinical Applications
- J.M. Harris, F.M. Veronese, Issue Eds, Theme Issue on Peptide and Protein PEGylation III-Advances in Chemistry and Clinical Applications, Adv. Drug Del. Rev. 60 (2008).
- (2008) Adv. Drug Del. Rev. , pp. 60
- Harris, J.M.¹ Veronese, F.M.²

2
- 75649099024
- S. Jevsevar, M. Kunstelj, V. Gaberic-Porekar, Biotech. J. 5, 113 (2010).
- (2010) Biotech. J. , vol.5 , pp. 113
- Jevsevar, S.¹ Kunstelj, M.² Gaberic-Porekar, V.³

3
- 27844515221
- C.J. Fee, J.M. Van Alstine, Chem. Eng. Sci. 61, 924 (2006).
- (2006) Chem. Eng. Sci. , vol.61 , pp. 924
- Fee, C.J.¹ Van Alstine, J.M.²

4
- 34547607522
- G. Pasut, F.M. Veronese, Prog. Polym. Sci. 32, 933 (2007).
- (2007) Prog. Polym. Sci. , vol.32 , pp. 933
- Pasut, G.¹ Veronese, F.M.²

5
- 70349988803
- G. Pasut, F.M. Veronese, Adv. Drug Del. Rev. 61, 1177 (2009).
- (2009) Adv. Drug Del. Rev. , vol.61 , pp. 1177
- Pasut, G.¹ Veronese, F.M.²

6
- 70349978292
- F. Greco, M.J. Vicent, Adv. Drug Del. Rev. 61, 1203 (2009).
- (2009) Adv. Drug Del. Rev. , vol.61 , pp. 1203
- Greco, F.¹ Vicent, M.J.²

7
- 0003472957
- Poly (ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
- Ed. Plenum Press: New Yorkz
- J.M. Harris, Ed., Poly (ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications, Plenum Press: New York, 1992.
- (1992)
- Harris, J.M.¹

8
- 0003472956
- Poly(ethylene Glycol): Chemistry and Biological Applications
- ACS Symposium Series 680, American Chemical Society, Washington, DC
- J.M. Harris, S. Zalipsky, Poly(ethylene Glycol): Chemistry and Biological Applications, ACS Symposium Series 680, American Chemical Society, Washington, DC, 1997.
- (1997)
- Harris, J.M.¹ Zalipsky, S.²

9
- 0037124506
- M.J. Roberts, M.D. Bently, J.M. Harris, Adv. Drug. Del. Rev. 54, 459 (2002).
- (2002) Adv. Drug. Del. Rev. , vol.54 , pp. 459
- Roberts, M.J.¹ Bently, M.D.² Harris, J.M.³

10
- 51549092094
- Biodrugs
- F.M. Veronese, A. Mero, Biodrugs 22, 315 (2008).
- (2008) , vol.22 , pp. 315
- Veronese, F.M.¹ Mero, A.²

11
- 0037124466
- A.P. Chapman, Adv. Drug Del. Rev. 54, 531 (2002).
- (2002) Adv. Drug Del. Rev. , vol.54 , pp. 531
- Chapman, A.P.¹

12
- 10744227326
- K. Yang, A. Basu, M. Wang, R. Chintala, M.-C. Hsieh, S. Liu, J. Hua, Z. Zhang, J. Zhou, M. Li, H. Phyu, G. Petti, M. Mendez, H. Janjua, P. Peng, C. Longley, V. Borowski, M. Mehlig, D. Filpula, Protein Eng. 16, 761 (2003).
- (2003) Protein Eng. , vol.16 , pp. 761
- Yang, K.¹ Basu, A.² Wang, M.³ Chintala, R.⁴ Hsieh, M.-C.⁵ Liu, S.⁶ Hua, J.⁷ Zhang, Z.⁸ Zhou, J.⁹ Li, M.¹⁰ Phyu, H.¹¹ Petti, G.¹² Mendez, M.¹³ Janjua, H.¹⁴ Peng, P.¹⁵ Longley, C.¹⁶ Borowski, V.¹⁷ Mehlig, M.¹⁸ Filpula, D.¹⁹

13
- 0026438972
- C. Delgado, G.E. Francis, D. Fisher, Crit. Rev. Ther. Drug Carrier Sys. 9, 249 (1992).
- (1992) Crit. Rev. Ther. Drug Carrier Sys. , vol.9 , pp. 249
- Delgado, C.¹ Francis, G.E.² Fisher, D.³

14
- 0001966352
- Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
- Ch. 14, In J.M. Harris, Ed., Plenum Press: New York
- E.W. Merrill, Ch. 14, In Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications, J.M. Harris, Ed., Plenum Press: New York, 1992.
- (1992)
- Merrill, E.W.¹

15
- 84954125630
- Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
- Ch. 10, In J.M. Harris, Ed., Plenum Press: New York
- A. Sehon, Ch. 10, In Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications, J.M. Harris, Ed., Plenum Press: New York, 1992.
- (1992)
- Sehon, A.¹

16
- 0011951522
- Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
- Ch. 5, In J.M. Harris, Ed., Plenum Press: New York
- G. Johansson, Ch. 5, In Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications, J.M. Harris, Ed., Plenum Press: New York, 1992.
- (1992)
- Johansson, G.¹

17
- 0017388651
- A. Abuchowski, J.R. McCoy, N.C. Palczuk, T. Van Es, F.F. Davis, J. Biol. Chem. 252, 3582 (1977).
- (1977) J. Biol. Chem. , vol.252 , pp. 3582
- Abuchowski, A.¹ McCoy, J.R.² Palczuk, N.C.³ Van Es, T.⁴ Davis, F.F.⁵

18
- 84954089307
- Oral Presentation, 4th International Partitioning Meeting
- Lund, August
- D. Fisher, Oral Presentation, 4th International Partitioning Meeting, Lund, August 1985.
- (1985)
- Fisher, D.¹

19
- 9244221679
- C.J. Fee, J.M. Van Alstine, Bioconj. Chem. 15, 1304 (2004).
- (2004) Bioconj. Chem. , vol.15 , pp. 1304
- Fee, C.J.¹ Van Alstine, J.M.²

20
- 0028955368
- T.-D. Brumeanu, H. Zaghouani, C. Bona, J. Chromatogr. A 696, 219 (1995).
- (1995) J. Chromatogr. A , vol.696 , pp. 219
- Brumeanu, T.-D.¹ Zaghouani, H.² Bona, C.³

21
- 0032868653
- A.P. Chapman, P. Antoniw, M. Spitali, S. West, S. Stephens, D.J. King, Nature Biotechnol. 17, 780 (1999).
- (1999) Nature Biotechnol. , vol.17 , pp. 780
- Chapman, A.P.¹ Antoniw, P.² Spitali, M.³ West, S.⁴ Stephens, S.⁵ King, D.J.⁶

22
- 0034732059
- I.L. Koumenis, Z. Shahrokh, S. Leong, V. Hsei, L. Deforge, G. Zapata, Int. J. Pharmaceut. 198, 83 (2002).
- (2002) Int. J. Pharmaceut. , vol.198 , pp. 83
- Koumenis, I.L.¹ Shahrokh, Z.² Leong, S.³ Hsei, V.⁴ Deforge, L.⁵ Zapata, G.⁶

23
- 0345504113
- L.S. Lee, C. Conover, C. Shi, M. Whitlow, D. Filpula, Bioconj. Chem. 10, 973 (1999).
- (1999) Bioconj. Chem. , vol.10 , pp. 973
- Lee, L.S.¹ Conover, C.² Shi, C.³ Whitlow, M.⁴ Filpula, D.⁵

24
- 0002938723
- Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
- Ch. 21, In J.M. Harris, Ed., Plenum Press: New York
- S. Zalipsky, C. Lee, Ch. 21, In Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications, J.M. Harris, Ed., Plenum Press: New York, 1992.
- (1992)
- Zalipsky, S.¹ Lee, C.²

25
- 0035816168
- R.B. Greenwald, J. Control. Rel. 74, 159 (2001).
- (2001) J. Control. Rel. , vol.74 , pp. 159
- Greenwald, R.B.¹

26
- 0023750391
- P. Pasta, S. Riva, G. Carrea, FEBS Lett. 236, 329 (1988).
- (1988) FEBS Lett. , vol.236 , pp. 329
- Pasta, P.¹ Riva, S.² Carrea, G.³

27
- 0032295673
- Y. Kodera, A. Matsushima, M. Hiroto, H. Nishimura, A. Ishii, T. Ueno, Y. Inada, Prog. Polym. Sci. 23, 1233 (1998).
- (1998) Prog. Polym. Sci. , vol.23 , pp. 1233
- Kodera, Y.¹ Matsushima, A.² Hiroto, M.³ Nishimura, H.⁴ Ishii, A.⁵ Ueno, T.⁶ Inada, Y.⁷

28
- 0036288833
- H. Lee, T.G. Park, Pharm. Res. 19, 845 (2002).
- (2002) Pharm. Res. , vol.19 , pp. 845
- Lee, H.¹ Park, T.G.²

29
- 0037223763
- H. Lee, T.G. Park, J. Pharm. Sci. 92, 97 (2002).
- (2002) J. Pharm. Sci. , vol.92 , pp. 97
- Lee, H.¹ Park, T.G.²

30
- 84954142627
- Presentation at Bioseparation 2004
- Uminonakamichi, Japan, October 15-17
- C.J. Fee, S. Mason, Presentation at Bioseparation 2004, Uminonakamichi, Japan, October 15-17 (2004).
- (2004)
- Fee, C.J.¹ Mason, S.²

31
- 0037124398
- Y.-S.Wang, S. Youngster, M. Grace, J. Bausch, R. Bordens, D.F. Wyss, Adv. Drug Del. Rev. 54, 547 (2002).
- (2002) Adv. Drug Del. Rev. , vol.54 , pp. 547
- Wang, Y.-S.¹ Youngster, S.² Grace, M.³ Bausch, J.⁴ Bordens, R.⁵ Wyss, D.F.⁶

32
- 0031001543
- C. Delgado, M. Malmsten, J.M. Van Alstine, J. Chromatogr. B 692, 263 (1997).
- (1997) J. Chromatogr. B , vol.692 , pp. 263
- Delgado, C.¹ Malmsten, M.² Van Alstine, J.M.³

33
- 84954121557
- available from GE Healthcare at
- MacroCap SP Data File 28-4005-84AA and Application Note 28-4094-65AA (2006) available from GE Healthcare at www.gelifesciences.com.
- (2006)

34
- 84954114204
- Protein Purification
- In 2nd Edn, J.-C. Jansson, L. Ryden, Eds, Wiley: New York
- L. Hagel, Gel Filtration, In Protein Purification, 2nd Edn, J.-C. Jansson, L. Ryden, Eds, Wiley: New York, 1998.
- (1998) Gel Filtration
- Hagel, L.¹

35
- 84954121931
- L. Hagel, A. Hartmann, K. Lund, J. Chromatogr. 641, 63 (1996).
- (1996) J. Chromatogr. , vol.641 , pp. 63
- Hagel, L.¹ Hartmann, A.² Lund, K.³

36
- 0031758396
- H. Holdaas, A. Hartmann, K.J. Berg, K. Lund, P. Fauchald, Nephrol. Dialy. Transplant 13, 3096 (1998).
- (1998) Nephrol. Dialy. Transplant , vol.13 , pp. 3096
- Holdaas, H.¹ Hartmann, A.² Berg, K.J.³ Lund, K.⁴ Fauchald, P.⁵

37
- 0023257807
- M. Potschka, Anal. Biochem. 162, 47 (1987).
- (1987) Anal. Biochem. , vol.162 , pp. 47
- Potschka, M.¹

38
- 0032469056
- P. Christakopoulos, E. Kourentzi, D.G. Hatzinikolaou, M. Claeyssens, D. Ketos, B.J. Macris, Carbohydrate Res. 314, 95 (1998).
- (1998) Carbohydrate Res. , vol.314 , pp. 95
- Christakopoulos, P.¹ Kourentzi, E.² Hatzinikolaou, D.G.³ Claeyssens, M.⁴ Ketos, D.⁵ Macris, B.J.⁶

39
- 0000409865
- G. Fortier, M. Laliberte, Biotechnol. Appl. Biochem. 17, 115 (1993).
- (1993) Biotechnol. Appl. Biochem. , vol.17 , pp. 115
- Fortier, G.¹ Laliberte, M.²

40
- 0023786636
- P. McGoff, A.C. Baziotis, R. Masckiewicz, Chem. Pharm. Bull. 36, 3079 (1988).
- (1988) Chem. Pharm. Bull. , vol.36 , pp. 3079
- McGoff, P.¹ Baziotis, A.C.² Masckiewicz, R.³

41
- 0035284411
- Biomaterials
- F.M. Veronese, Biomaterials 22, 405 (2001).
- (2001) , vol.22 , pp. 405
- Veronese, F.M.¹

42
- 0000901087
- H. Benoit, Z. Gallot-Grubisic, P. Rempp, D. Decker, J.G. Zilliox, J. Chimie Physique 63, 1507 (1966).
- (1966) J. Chimie Physique , vol.63 , pp. 1507
- Benoit, H.¹ Gallot-Grubisic, Z.² Rempp, P.³ Decker, D.⁴ Zilliox, J.G.⁵

43
- 0000576265
- S. Kuga, J. Chromatogr. 206, 449 (1981).
- (1981) J. Chromatogr. , vol.206 , pp. 449
- Kuga, S.¹

44
- 0023058254
- L.J. Karr, S.G. Shafer, J.M. Harris, J.M. Van Alstine, R.S. Snyder, J. Chromatogr. 354, 269 (1986).
- (1986) J. Chromatogr. , vol.354 , pp. 269
- Karr, L.J.¹ Shafer, S.G.² Harris, J.M.³ Van Alstine, J.M.⁴ Snyder, R.S.⁵

45
- 0024290499
- L.J. Karr, J.M. Van Alstine, R.S. Snyder, S.G. Shafer, J.M. Harris, J. Chromatogr. 442, 219 (1988).
- (1988) J. Chromatogr. , vol.442 , pp. 219
- Karr, L.J.¹ Van Alstine, J.M.² Snyder, R.S.³ Shafer, S.G.⁴ Harris, J.M.⁵

46
- 33947502313
- T.M. Pabst, J.J. Buckley, N. Ramasubramanyan, A.K. Hunter, J. Chromatogr. A 1147, 172 (2007).
- (2007) J. Chromatogr. A , vol.1147 , pp. 172
- Pabst, T.M.¹ Buckley, J.J.² Ramasubramanyan, N.³ Hunter, A.K.⁴

47
- 84954192206
- US Patent
- J.M. Van Alstine, US Patent 5, 108, 568 (1992).
- (1992) , vol.108 , pp. 568
- Van Alstine, J.M.¹

48
- 0026536995
- M.M. Kurfurst, Anal. Biochem. 200, 244 (1992).
- (1992) Anal. Biochem. , vol.200 , pp. 244
- Kurfurst, M.M.¹

49
- 15644362966
- D.K. Pettit, T.P. Bonnert, J. Eisenman, S. Srinivasan, R. Paxton, C. Beers, D. Lynch, B. Miller, J. Yost, K.H. Grabstein, W.R. Gombotz, J. Biol. Chem. 272, 2312 (1996).
- (1996) J. Biol. Chem. , vol.272 , pp. 2312
- Pettit, D.K.¹ Bonnert, T.P.² Eisenman, J.³ Srinivasan, S.⁴ Paxton, R.⁵ Beers, C.⁶ Lynch, D.⁷ Miller, B.⁸ Yost, J.⁹ Grabstein, K.H.¹⁰ Gombotz, W.R.¹¹

50
- 2942534489
- P. Calceti, S. Salmaso, G. Walker, A. Bernkop-Schnurch, Eur. J. Pharm. Sci. 22, 315 (2004).
- (2004) Eur. J. Pharm. Sci. , vol.22 , pp. 315
- Calceti, P.¹ Salmaso, S.² Walker, G.³ Bernkop-Schnurch, A.⁴

51
- 0028395406
- S.C. Chamow, T.P. Kogan, M. Venuti, T. Gadek, R.J. Harris, D.H. Peers, J. Mordenti, S. Shak, A. Ashkenazi, Bioconj. Chem. 5, 133 (1994).
- (1994) Bioconj. Chem. , vol.5 , pp. 133
- Chamow, S.C.¹ Kogan, T.P.² Venuti, M.³ Gadek, T.⁴ Harris, R.J.⁵ Peers, D.H.⁶ Mordenti, J.⁷ Shak, S.⁸ Ashkenazi, A.⁹

52
- 0345283166
- P. Esposito, L. Barbero, P. Caccia, P. Caliceti, M. D'Antonio, G. Piquet, F.M. Veronese, Adv. Drug Del. Rev. 55, 1279 (2003).
- (2003) Adv. Drug Del. Rev. , vol.55 , pp. 1279
- Esposito, P.¹ Barbero, L.² Caccia, P.³ Caliceti, P.⁴ D'Antonio, M.⁵ Piquet, G.⁶ Veronese, F.M.⁷

53
- 84954128089
- Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
- In J.M. Harris, Ed., Plenum Press: New York
- H. Maeda, M. Kimura, I. Sasaki, Y. Hirose, T. Konno, In Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications, J.M. Harris, Ed., Plenum Press: New York, 1992.
- , vol.1992
- Maeda, H.¹ Kimura, M.² Sasaki, I.³ Hirose, Y.⁴ Konno, T.⁵

54
- 0032211606
- P. Bailon, W. Berthold, Pharm. Sci. Technol. Today 1, 352 (1998).
- (1998) Pharm. Sci. Technol. Today , vol.1 , pp. 352
- Bailon, P.¹ Berthold, W.²

55
- 0032007236
- Y. Tan, X. Sun, M. Xu, Z. An, X. Tan, X. Tan, Q. Han, D.A. Miljkovic, M. Yang, R.M. Hoffman, Prot. Expr. Purif. 12, 45 (1998).
- (1998) Prot. Expr. Purif. , vol.12 , pp. 45
- Tan, Y.¹ Sun, X.² Xu, M.³ An, Z.⁴ Tan, X.⁵ Tan, X.⁶ Han, Q.⁷ Miljkovic, D.A.⁸ Yang, M.⁹ Hoffman, R.M.¹⁰

56
- 0344851745
- C.K. Edwards, S.W. Martin, J. Seely, O. Kinstler, S. Buckel, A.M. Bendele, M.E. Cosenza, U. Feige, T. Kohno, Adv. Drug Del. Rev. 55, 1315 (2003).
- (2003) Adv. Drug Del. Rev. , vol.55 , pp. 1315
- Edwards, C.K.¹ Martin, S.W.² Seely, J.³ Kinstler, O.⁴ Buckel, S.⁵ Bendele, A.M.⁶ Cosenza, M.E.⁷ Feige, U.⁸ Kohno, T.⁹

57
- 33749369528
- J.R. Molek, A.L. Zydney, Biotech. Bioeng. 95, 474 (2006).
- (2006) Biotech. Bioeng. , vol.95 , pp. 474
- Molek, J.R.¹ Zydney, A.L.²

58
- 37149047514
- J.R. Molek, A.L. Zydney, Biotechnol. Prog. 23, 1417 (2007).
- (2007) Biotechnol. Prog. , vol.23 , pp. 1417
- Molek, J.R.¹ Zydney, A.L.²

59
- 44249102502
- B. Kwon, J.R. Molek, A.L. Zydney, J. Memb. Sci. 319, 206 (2008).
- (2008) J. Memb. Sci. , vol.319 , pp. 206
- Kwon, B.¹ Molek, J.R.² Zydney, A.L.³

60
- 0032526793
- M. Malmsten, K. Emoto, J.M. Van Alstine, J. Colloid Interf. Sci. 202, 507 (1998).
- (1998) J. Colloid Interf. Sci. , vol.202 , pp. 507
- Malmsten, M.¹ Emoto, K.² Van Alstine, J.M.³

61
- 84954177481
- Use of Differential Solubilities for Purification of Polymer Modified Proteins and other Substances
- IP.com publication 000157698D, Use of Differential Solubilities for Purification of Polymer Modified Proteins and other Substances, www.ip.com (2008).
- (2008)

62
- 0035951339
- J.E. Seely, C.W. Richey, J. Chromatogr. A 908, 235 (2001).
- (2001) J. Chromatogr. A , vol.908 , pp. 235
- Seely, J.E.¹ Richey, C.W.²

63
- 77953706804
- R. Clark, K. Olson, G. Fuh, M. Marian, D. Mortensen, G. Teshima, S. Chang, H. Chu, V. Mukku, E. Canova-Davis, T. Somers, M. Cronin, M. Winkler, J.A. Wells, J. Biol. Chem. 271, 969 (1996).
- (1996) J. Biol. Chem. , vol.271 , pp. 969
- Clark, R.¹ Olson, K.² Fuh, G.³ Marian, M.⁴ Mortensen, D.⁵ Teshima, G.⁶ Chang, S.⁷ Chu, H.⁸ Mukku, V.⁹ Canova-Davis, E.¹⁰ Somers, T.¹¹ Cronin, M.¹² Winkler, M.¹³ Wells, J.A.¹⁴

64
- 0031553986
- M. Nijs, M. Azarkan, N. Smolders, J. Brygier, J. Vincentelli, G.M.P.-d Vries, J. Duchateau, Y. Looze, Biotechnol. Bioeng. 54, 40 (1997).
- (1997) Biotechnol. Bioeng. , vol.54 , pp. 40
- Nijs, M.¹ Azarkan, M.² Smolders, N.³ Brygier, J.⁴ Vincentelli, J.⁵ Vries, G.M.P.-D.⁶ Duchateau, J.⁷ Looze, Y.⁸

65
- 0032932234
- J. Vincentelli, C. Paul, M. Azarkan, C. Guermant, A. El Moussaoui, Y. Looze, Int. J. Pharm. 176, 241 (1999).
- (1999) Int. J. Pharm. , vol.176 , pp. 241
- Vincentelli, J.¹ Paul, C.² Azarkan, M.³ Guermant, C.⁴ El Moussaoui, A.⁵ Looze, Y.⁶

66
- 0030592490
- M. Azarkan, D. Maes, J. Bouckaert, M.-H.D. Thi, L. Wyns, Y. Looze, J. Chromatogr. A 749, 69 (1996).
- (1996) J. Chromatogr. A , vol.749 , pp. 69
- Azarkan, M.¹ Maes, D.² Bouckaert, J.³ Thi, M.-H.D.⁴ Wyns, L.⁵ Looze, Y.⁶

67
- 0038739364
- M. Azarkan, A. El Moussaoui, D. Van Wuytswinkel, G. Dehon, Y. Looze, J. Chromatogr. B 790, 229 (2003).
- (2003) J. Chromatogr. B , vol.790 , pp. 229
- Azarkan, M.¹ El Moussaoui, A.² Van Wuytswinkel, D.³ Dehon, G.⁴ Looze, Y.⁵

68
- 0033055121
- K.C. Lee, S.C. Moon, M.O. Park, J.T. Lee, D.H. Na, S.D. Yoo, H.S. Lee, P.P. DeLuca, Pharm. Res. 16, 813 (1999).
- (1999) Pharm. Res. , vol.16 , pp. 813
- Lee, K.C.¹ Moon, S.C.² Park, M.O.³ Lee, J.T.⁴ Na, D.H.⁵ Yoo, S.D.⁶ Lee, H.S.⁷ DeLuca, P.P.⁸

69
- 0042564651
- C. Johnson, M. Royal, R. Moreadith, F. Bedu-Addo, S. Advant, M. Wan, G. Conn, Biomed. Chromatogr. 17, 335 (2003).
- (2003) Biomed. Chromatogr. , vol.17 , pp. 335
- Johnson, C.¹ Royal, M.² Moreadith, R.³ Bedu-Addo, F.⁴ Advant, S.⁵ Wan, M.⁶ Conn, G.⁷

70
- 0003472957
- Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
- In J.M. Harris, Ed., Plenum Press: New York
- F.M. Veronese, P. Calceti, O. Schiavon, L. Sartore, In Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications, J.M. Harris, Ed., Plenum Press: New York, 1992.
- (1992)
- Veronese, F.M.¹ Calceti, P.² Schiavon, O.³ Sartore, L.⁴

71
- 0037124508
- K.R. Reddy, M. Modi, S. Pedder, Adv. Drug Del. Rev. 54, 571 (2002).
- (2002) Adv. Drug Del. Rev. , vol.54 , pp. 571
- Reddy, K.R.¹ Modi, M.² Pedder, S.³

72
- 0345283158
- R. Moreadith, D. Collen, Adv. Drug Del. Rev. 55, 1337 (2003).
- (2003) Adv. Drug Del. Rev. , vol.55 , pp. 1337
- Moreadith, R.¹ Collen, D.²

73
- 12444305299
- Y. Yamamoto, Y. Tsutsumi, Y. Yoshioka, T. Nishibata, K. Kobayashi, T. Okamoto, Y. Mukai, T. Shimizu, S. Nakagawa, S. Nagata, T. Mayumi, Nature Biotechnol. 21, 546 (2003).
- (2003) Nature Biotechnol. , vol.21 , pp. 546
- Yamamoto, Y.¹ Tsutsumi, Y.² Yoshioka, Y.³ Nishibata, T.⁴ Kobayashi, K.⁵ Okamoto, T.⁶ Mukai, Y.⁷ Shimizu, T.⁸ Nakagawa, S.⁹ Nagata, S.¹⁰ Mayumi, T.¹¹

74
- 84954183612
- Solid-Phase, N-Terminus-Specific, Mono-PEGylation of Recombinant lnterferon-Alpha-2a: Purification, Characterization, and Bioactivity
- In International Symposium on the Separation of Proteins, Peptides, and Polynucleotides, Aachen, Federal Republic of Germany, October 19-22
- E.K. Lee, J.D. Lee, In Solid-Phase, N-Terminus-Specific, Mono-PEGylation of Recombinant lnterferon-Alpha-2a: Purification, Characterization, and Bioactivity, International Symposium on the Separation of Proteins, Peptides, and Polynucleotides, Aachen, Federal Republic of Germany, October 19-22, 2004.
- (2004)
- Lee, E.K.¹ Lee, J.D.²

75
- 12144290746
- R.M. Arduini, Z. Li, A. Rapoza, R. Gronke, D.M. Hess, D. Wen, K. Miatkowski, C. Coots, A. Kaffashan, N. Viseux, Protein Expr. Purif. 34, 229 (2004).
- (2004) Protein Expr. Purif. , vol.34 , pp. 229
- Arduini, R.M.¹ Li, Z.² Rapoza, A.³ Gronke, R.⁴ Hess, D.M.⁵ Wen, D.⁶ Miatkowski, K.⁷ Coots, C.⁸ Kaffashan, A.⁹ Viseux, N.¹⁰

76
- 0036079378
- S. Arpicco, F. Dosio, A. Bolognesi, C. Lubelli, P. Brusa, B. Stella, M. Ceruti, L. Cattel, Bioconj. Chem. 13, 757 (2002).
- (2002) Bioconj. Chem. , vol.13 , pp. 757
- Arpicco, S.¹ Dosio, F.² Bolognesi, A.³ Lubelli, C.⁴ Brusa, P.⁵ Stella, B.⁶ Ceruti, M.⁷ Cattel, L.⁸

77
- 0042830593
- E.T. Baran, N. Ozer, V. Hasirci, J. Chromatogr. B 794, 311 (2003).
- (2003) J. Chromatogr. B , vol.794 , pp. 311
- Baran, E.T.¹ Ozer, N.² Hasirci, V.³

78
- 0037457502
- C.J. Fee, Biotech. Bioeng. 82, 200 (2003).
- (2003) Biotech. Bioeng. , vol.82 , pp. 200
- Fee, C.J.¹

79
- 2942594025
- T. Hall, D.C. Wood, C.E. Smith, J. Chromatogr. A 1041, 87 (2004).
- (2004) J. Chromatogr. A , vol.1041 , pp. 87
- Hall, T.¹ Wood, D.C.² Smith, C.E.³

80
- 0033580768
- X.-H. He, P.-C. Shaw, S.-C. Tam, Life Sci. 65, 355 (1999).
- (1999) Life Sci. , vol.65 , pp. 355
- He, X.-H.¹ Shaw, P.-C.² Tam, S.-C.³

81
- 0037124501
- K.D. Hinds, S.W. Kim, Adv. Drug Del. Rev. 54, 505 (2002).
- (2002) Adv. Drug Del. Rev. , vol.54 , pp. 505
- Hinds, K.D.¹ Kim, S.W.²

82
- 0036128917
- Biomaterials
- T.H. Kim, H. Lee, T.G. Park, Biomaterials 23, 2311 (2002).
- (2002) , vol.23 , pp. 2311
- Kim, T.H.¹ Lee, H.² Park, T.G.³

83
- 0037124498
- O. Kinstler, G. Molineux, M. Treuheit, D. Ladd, C. Gegg, Adv. Drug Del. Rev. 54, 477 (2002).
- (2002) Adv. Drug Del. Rev. , vol.54 , pp. 477
- Kinstler, O.¹ Molineux, G.² Treuheit, M.³ Ladd, D.⁴ Gegg, C.⁵

84
- 0035808641
- W. Li, Y. Zhong, B. Lin, Z. Su, J. Chromatogr. A 905, 299 (2001).
- (2001) J. Chromatogr. A , vol.905 , pp. 299
- Li, W.¹ Zhong, Y.² Lin, B.³ Su, Z.⁴

85
- 0037343959
- B.N. Manjula, A. Tsai, R. Upadhya, K. Perumalsamy, P.K. Smith, A. Malavalli, K. Vandegriff, R.M. Winslow, M. Intaglietta, M. Prabhakaran, J.M. Friedman, A.S. Acharya, Bioconjug. Chem. 14, 464 (2003).
- (2003) Bioconjug. Chem. , vol.14 , pp. 464
- Manjula, B.N.¹ Tsai, A.² Upadhya, R.³ Perumalsamy, K.⁴ Smith, P.K.⁵ Malavalli, A.⁶ Vandegriff, K.⁷ Winslow, R.M.⁸ Intaglietta, M.⁹ Prabhakaran, M.¹⁰ Friedman, J.M.¹¹ Acharya, A.S.¹²

86
- 3242684181
- D.H. Na, K.C. Lee, Anal. Biochem. 331, 322 (2004).
- (2004) Anal. Biochem. , vol.331 , pp. 322
- Na, D.H.¹ Lee, K.C.²

87
- 0037168961
- G. Piquet, M. Gatti, L. Barbero, S. Traversa, P. Caccia, P. Esposito, J. Chromatogr. A 944, 141 (2002).
- (2002) J. Chromatogr. A , vol.944 , pp. 141
- Piquet, G.¹ Gatti, M.² Barbero, L.³ Traversa, S.⁴ Caccia, P.⁵ Esposito, P.⁶

88
- 0037124507
- H. Sato, Adv. Drug Del. Rev. 54, 487 (2002).
- (2002) Adv. Drug Del. Rev. , vol.54 , pp. 487
- Sato, H.¹

89
- 0033841450
- Il Farmaco
- O. Schiavon, P. Caliceti, P. Ferruti, F.M. Veronese, Il Farmaco 55, 264 (2000).
- (2000) , vol.55 , pp. 264
- Schiavon, O.¹ Caliceti, P.² Ferruti, P.³ Veronese, F.M.⁴

90
- 4344569316
- M.R. Stoner, N. Fischer, L. Nixon, S. Buckel, M. Benke, F. Austin, T.W. Randolph, B.S. Kendrick, J. Pharm. Sci. 93, 2332 (2004).
- (2004) J. Pharm. Sci. , vol.93 , pp. 2332
- Stoner, M.R.¹ Fischer, N.² Nixon, L.³ Buckel, S.⁴ Benke, M.⁵ Austin, F.⁶ Randolph, T.W.⁷ Kendrick, B.S.⁸

91
- 0035141781
- F.M. Veronese, B. Sacca, P.P.-d. Laureto, M. Sergi, P. Caliceti, O. Schiavon, P. Orsolini, Bioconj. Chem. 12, 62 (2001).
- (2001) Bioconj. Chem. , vol.12 , pp. 62
- Veronese, F.M.¹ Sacca, B.² Laureto, P.P.-D.³ Sergi, M.⁴ Caliceti, P.⁵ Schiavon, O.⁶ Orsolini, P.⁷

92
- 0034848092
- D.C. Wylie, M. Voloch, S. Lee, Y.-H. Liu, S. Cannon-Carlson, A. Cutler, B. Pramanik, Pharm. Res. 18, 1354 (2001).
- (2001) Pharm. Res. , vol.18 , pp. 1354
- Wylie, D.C.¹ Voloch, M.² Lee, S.³ Liu, Y.-H.⁴ Cannon-Carlson, S.⁵ Cutler, A.⁶ Pramanik, B.⁷

93
- 35348946448
- S. Yamamoto, F. Sachie, N. Noriko Yoshimoto, P. Akbarzadehlaleh, J. Biotechnol. 132, 196 (2007).
- (2007) J. Biotechnol. , vol.132 , pp. 196
- Yamamoto, S.¹ Sachie, F.² Noriko Yoshimoto, N.³ Akbarzadehlaleh, P.⁴

94
- 0030202039
- Prep. Biochem. Biotechnol.
- R. Hecht, T. Tressel, V. Goldshteyn, D. Winters, J. Wilson, T. Boone, M. Daniels, Prep. Biochem. Biotechnol. 26 (3-4), 201 (1996).
- (1996) , vol.26 , Issue.3-4 , pp. 201
- Hecht, R.¹ Tressel, T.² Goldshteyn, V.³ Winters, D.⁴ Wilson, J.⁵ Boone, T.⁶ Daniels, M.⁷

95
- 0029759584
- O.B. Kinstler, D.N. Brems, S.L. Lauren, A.G. Paige, J.B. Hamburger, M.J. Treuheit, Pharm. Res. 13, 996 (1996).
- (1996) Pharm. Res. , vol.13 , pp. 996
- Kinstler, O.B.¹ Brems, D.N.² Lauren, S.L.³ Paige, A.G.⁴ Hamburger, J.B.⁵ Treuheit, M.J.⁶

96
- 39449114209
- D.L. Lee, I. Sharif, S. Kodijalli, D.I.H. Stewart, V. Tsvetnitsky, J. Interferon Cytokine Res. 28, 101 (2008).
- (2008) J. Interferon Cytokine Res. , vol.28 , pp. 101
- Lee, D.L.¹ Sharif, I.² Kodijalli, S.³ Stewart, D.I.H.⁴ Tsvetnitsky, V.⁵

97
- 0003472956
- Poly(ethylene Glycol): Chemistry and Biological Applications
- In J.M. Harris, S. Zalipsky, Eds, American Chemical Society: Washington DC
- M.R. Sherman, L.D. Williams, M.G.P. Saifer, J.A. French, L.W. Kwak, J.J. Oppenheim, In Poly(ethylene Glycol): Chemistry and Biological Applications, J.M. Harris, S. Zalipsky, Eds, American Chemical Society: Washington DC, 1997.
- (1997)
- Sherman, M.R.¹ Williams, L.D.² Saifer, M.G.P.³ French, J.A.⁴ Kwak, L.W.⁵ Oppenheim, J.J.⁶

98
- 0003472956
- Poly(ethylene Glycol): Chemistry and Biological Applications
- In J.M. Harris, S. Zalipsky, Eds, American Chemical Society: Washington DC
- K. Olson, R. Gehant, V. Mukku, K. O'Connell, B. Tomlinson, K. Totpal, M. Winkler, In Poly(ethylene Glycol): Chemistry and Biological Applications, J.M. Harris, S. Zalipsky, Eds, American Chemical Society: Washington DC, 1997.
- (1997)
- Olson, K.¹ Gehant, R.² Mukku, V.³ O'Connell, K.⁴ Tomlinson, B.⁵ Totpal, K.⁶ Winkler, M.⁷

99
- 0030200252
- Biomaterials
- P. Turbill, T. Beugeling, A.A. Poot, Biomaterials 17, 1279 (1996).
- (1996) , vol.17 , pp. 1279
- Turbill, P.¹ Beugeling, T.² Poot, A.A.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.