Therapeutic proteins: A comparison of chemical and biological properties of uricase conjugated to linear or branched poly(ethylene glycol) and poly(N- acryloylmorpholine)

Farmaco

Volumn 55, Issue 4, 2000, Pages 264-269

  Schiavon, O ^a   Caliceti, P ^a   Ferruti, P ^b   Veronese, F M ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Branched PEG; PEG; PEGylation; Poly(N acryloylmorpholine); Therapeutic proteins; Uricase

Indexed keywords

MACROGOL; MORPHOLINE DERIVATIVE; URATE OXIDASE;

ANIMAL EXPERIMENT; ARTICLE; BACILLUS; CONJUGATION; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME MODIFICATION; MALE; MOUSE; NONHUMAN;

ACRYLIC RESINS; ANIMALS; BACILLUS; ENZYME STABILITY; MALE; MICE; MICE, INBRED BALB C; POLYETHYLENE GLYCOLS; TRYPSIN; URATE OXIDASE;

EID: 0033841450     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(00)00031-8     Document Type: Article

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