Comparison of strong anion-exchangers for the purification of a PEGylated protein

Journal of Chromatography A

Volumn 1147, Issue 2, 2007, Pages 172-182

  Pabst, Timothy M ^a,b   Buckley, John J ^a   Ramasubramanyan, Natraj ^a   Hunter, Alan K ^a  

^a PFIZER INC   (United States)

^b University of Virginia   (United States)

Author keywords

Chromatography; Ion exchange; PEGylation; Protein; Purification

Indexed keywords

ION EXCHANGE; NEGATIVE IONS; POLYETHYLENE GLYCOLS; PURIFICATION; SIZE EXCLUSION CHROMATOGRAPHY;

DYNAMIC BINDING; FRONTAL ANALYSIS; PEGYLATION;

PROTEINS;

AGAROSE; BOVINE SERUM ALBUMIN; CYSTEINE; MACROGOL; MALEIMIDE; PROTEIN; THIOL DERIVATIVE;

ANALYTIC METHOD; ANION EXCHANGE; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONJUGATE; ELECTRICITY; ELUTION; GEL PERMEATION CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; POROSITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; QUANTUM YIELD; REACTION ANALYSIS;

ANION EXCHANGE RESINS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; POLYETHYLENE GLYCOLS; PROTEINS;

BOVINAE;

EID: 33947502313     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.02.051     Document Type: Article

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