메뉴 건너뛰기




Volumn 45, Issue 4, 2011, Pages 667-674

Targeting eosinophil biology in asthma therapy

Author keywords

Asthma; CCR 3; Eosinophil; IL 5; Prostanoid receptor

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; BENRALIZUMAB; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR3 ANTAGONIST; CHEMOKINE RECEPTOR CCR3 ANTIBODY; CORTICOSTEROID; CYTOKINE ANTIBODY; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR ANTIBODY; GSK 766994; GW 701897B; IMMUNOLOGIC AGENT; INTERLEUKIN 3; INTERLEUKIN 3 ANTIBODY; INTERLEUKIN 5; INTERLEUKIN 5 ANTIBODY; INTERLEUKIN 5 RECEPTOR ALPHA; MEPOLIZUMAB; MONOCLONAL ANTIBODY; PIPERIDINE DERIVATIVE; PLACEBO; RECEPTOR ANTIBODY; RESLIZUMAB; TPI ASM8; UNCLASSIFIED DRUG; UNINDEXED DRUG; YM 344031; YM 344484; YM 355179;

EID: 80053644690     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0013TR     Document Type: Review
Times cited : (54)

References (115)
  • 2
    • 73149089686 scopus 로고    scopus 로고
    • Eosinophils and allergic airway disease: There is more to the story
    • Walsh ER, August A. Eosinophils and allergic airway disease: there is more to the story. Trends Immunol 2010;31:39-44.
    • (2010) Trends Immunol , vol.31 , pp. 39-44
    • Walsh, E.R.1    August, A.2
  • 9
    • 0030028768 scopus 로고    scopus 로고
    • Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
    • DOI 10.1084/jem.183.1.195
    • Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 1996;183:195-201. (Pubitemid 26028759)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.1 , pp. 195-201
    • Foster, P.S.1    Hogan, S.P.2    Ramsay, A.J.3    Matthaei, K.I.4    Young, I.G.5
  • 19
    • 77952737928 scopus 로고    scopus 로고
    • IL-5 pathway inhibition in the treatment of asthma and Churg-Strauss syndrome
    • Rosenwasser LJ, Rothenberg ME. IL-5 pathway inhibition in the treatment of asthma and Churg-Strauss syndrome. J Allergy Clin Immunol 2010;125:1245-1246.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 1245-1246
    • Rosenwasser, L.J.1    Rothenberg, M.E.2
  • 20
    • 77952683218 scopus 로고    scopus 로고
    • Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma
    • Busse WW, Katial R, Gossage D, Sari S, Wang B, Kolbeck R, Coyle AJ, Koike M, Spitalny GL, Kiener PA, et al. Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma. J Allergy Clin Immunol 2010;125:1237-1244.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 1237-1244
    • Busse, W.W.1    Katial, R.2    Gossage, D.3    Sari, S.4    Wang, B.5    Kolbeck, R.6    Coyle, A.J.7    Koike, M.8    Spitalny, G.L.9    Kiener, P.A.10
  • 21
    • 0025963596 scopus 로고
    • Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects
    • Kay AB, Ying S, Varney V, Gaga M, Durham SR, Moqbel R, Wardlaw AJ, Hamid Q. Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects. J Exp Med 1991;173:775-778.
    • (1991) J Exp Med , vol.173 , pp. 775-778
    • Kay, A.B.1    Ying, S.2    Varney, V.3    Gaga, M.4    Durham, S.R.5    Moqbel, R.6    Wardlaw, A.J.7    Hamid, Q.8
  • 22
    • 0026355491 scopus 로고
    • Control of granulocytes and macrophages: Molecular, cellular, and clinical aspects
    • Metcalf D. Control of granulocytes and macrophages: molecular, cellular, and clinical aspects. Science 1991;254:529-533. (Pubitemid 21917365)
    • (1991) Science , vol.254 , Issue.5031 , pp. 529-533
    • Metcalf, D.1
  • 23
    • 0031569468 scopus 로고    scopus 로고
    • Direct Demonstration of Delayed Eosinophil Apoptosis as a Mechanism Causing Tissue Eosinophilia
    • Simon HU, Yousefi S, Schranz C, Schapowal A, Bachert C, Blaser K. Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia. J Immunol 1997;158:3902-3908. (Pubitemid 127488750)
    • (1997) Journal of Immunology , vol.158 , Issue.8 , pp. 3902-3908
    • Simon, H.-U.1    Yousefi, S.2    Schranz, C.3    Schapowal, A.4    Bachert, C.5    Blaser, K.6
  • 24
    • 0028907399 scopus 로고
    • Eosinophil viability-enhancing activity in sputum from patients with bronchial asthma: Contributions of interleukin-5 and granulocyte/macrophage colony-stimulating factor
    • Adachi T, Motojima S, Hirata A, Fukuda T, Makino S. Eosinophil viability-enhancing activity in sputum from patients with bronchial asthma: contributions of interleukin-5 and granulocyte/macrophage colony-stimulating factor. Am J Respir Crit Care Med 1995;151:618-623.
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 618-623
    • Adachi, T.1    Motojima, S.2    Hirata, A.3    Fukuda, T.4    Makino, S.5
  • 25
    • 0028005446 scopus 로고
    • Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF
    • Woodcock JM, Zacharakis B, Plaetinck G, Bagley CJ, Qiyu S, Hercus TR, Tavernier J, Lopez AF. Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J 1994;13:5176-5185. (Pubitemid 24341099)
    • (1994) EMBO Journal , vol.13 , Issue.21 , pp. 5176-5185
    • Woodcock, J.M.1    Zacharakis, B.2    Plaetinck, G.3    Bagley, C.J.4    Qiyu, S.5    Hercus, T.R.6    Tavernier, J.7    Lopez, A.F.8
  • 26
    • 0029860206 scopus 로고    scopus 로고
    • A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL- 5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all three ligands
    • DOI 10.1074/jbc.271.42.25999
    • Woodcock JM, Bagley CJ, Zacharakis B, Lopez AF. A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all three ligands. J Biol Chem 1996;271:25999-26006. (Pubitemid 26347437)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.42 , pp. 25999-26006
    • Woodcock, J.M.1    Bagley, C.J.2    Zacharakis, B.3    Lopez, A.F.4
  • 27
    • 0029881372 scopus 로고    scopus 로고
    • Functional inactivation in mice of the gene for the interleukin-3 (IL-3)-specific receptor beta-chain: Implications for IL-3 function and the mechanism of receptor transmodulation in hematopoietic cells
    • Nicola NA, Robb L, Metcalf D, Cary D, Drinkwater CC, Begley CG. Functional inactivation in mice of the gene for the interleukin-3 (IL-3)-specific receptor beta-chain: implications for IL-3 function and the mechanism of receptor transmodulation in hematopoietic cells. Blood 1996;87:2665-2674.
    • (1996) Blood , vol.87 , pp. 2665-2674
    • Nicola, N.A.1    Robb, L.2    Metcalf, D.3    Cary, D.4    Drinkwater, C.C.5    Begley, C.G.6
  • 28
    • 0033565287 scopus 로고    scopus 로고
    • A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation
    • Adachi T, Stafford S, Sur S, Alam R. A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation. J Immunol 1999;163:939-946. (Pubitemid 29328105)
    • (1999) Journal of Immunology , vol.163 , Issue.2 , pp. 939-946
    • Adachi, T.1    Stafford, S.2    Sur, S.3    Alam, R.4
  • 29
    • 0033568467 scopus 로고    scopus 로고
    • Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony- stimulating factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine binding site of their receptors
    • Sun Q, Jones K, McClure B, Cambareri B, Zacharakis B, Iversen PO, Stomski F, Woodcock JM, Bagley CJ, D'Andrea R, et al. Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony-stimulating factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine binding site of their receptors. Blood 1999;94:1943-1951. (Pubitemid 29430410)
    • (1999) Blood , vol.94 , Issue.6 , pp. 1943-1951
    • Sun, Q.1    Jones, K.2    McClure, B.3    Cambareri, B.4    Zacharakis, B.5    Iversen, P.O.6    Stomski, F.7    Woodcock, J.M.8    Bagley, C.J.9    D'Andrea, R.10    Lopez, A.F.11
  • 30
    • 0036528907 scopus 로고    scopus 로고
    • Inhibition of antigen-induced eosinophilia and airway hyperresponsiveness by antisense oligonucleotides directed against the common beta chain of IL-3, IL-5, GM-CSF receptors in a rat model of allergic asthma
    • Allakhverdi Z, Allam M, Renzi PM. Inhibition of antigen-induced eosinophilia and airway hyperresponsiveness by antisense oligonucleotides directed against the common beta chain of IL-3, IL-5, GM-CSF receptors in a rat model of allergic asthma. Am J Respir Crit Care Med 2002;165:1015-1021. (Pubitemid 34774674)
    • (2002) American Journal of Respiratory and Critical Care Medicine , vol.165 , Issue.7 , pp. 1015-1021
    • Allakhverdi, Z.1    Allam, M.2    Renzi, P.M.3
  • 35
    • 0031445441 scopus 로고    scopus 로고
    • Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells
    • DOI 10.1002/eji.1830271252
    • Ying S, Robinson DS, Meng Q, Rottman J, Kennedy R, Ringler DJ, Mackay CR, Daugherty BL, Springer MS, Durham SR, et al. Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma: association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells. Eur J Immunol 1997;27:3507-3516. (Pubitemid 28018050)
    • (1997) European Journal of Immunology , vol.27 , Issue.12 , pp. 3507-3516
    • Ying, S.1    Robinson, D.S.2    Meng, Q.3    Rottman, J.4    Kennedy, R.5    Ringler, D.J.6    Mackay, C.R.7    Daugherty, B.L.8    Springer, M.S.9    Durham, S.R.10    Williams, T.J.11    Kay, A.B.12
  • 38
    • 0029148025 scopus 로고
    • Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo
    • Collins PD, Marleau S, Griffiths-Johnson DA, Jose PJ, Williams TJ. Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. J Exp Med 1995;182:1169-1174.
    • (1995) J Exp Med , vol.182 , pp. 1169-1174
    • Collins, P.D.1    Marleau, S.2    Griffiths-Johnson, D.A.3    Jose, P.J.4    Williams, T.J.5
  • 39
    • 0034651784 scopus 로고    scopus 로고
    • The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity
    • Mould AW, Ramsay AJ, Matthaei KI, Young IG, Rothenberg ME, Foster PS. The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity. J Immunol 2000;164:2142-2150. (Pubitemid 30108773)
    • (2000) Journal of Immunology , vol.164 , Issue.4 , pp. 2142-2150
    • Mould, A.W.1    Ramsay, A.J.2    Matthaei, K.I.3    Young, I.G.4    Rothenberg, M.E.5    Foster, P.S.6
  • 40
    • 26844435631 scopus 로고    scopus 로고
    • The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia
    • Pope SM, Zimmermann N, Stringer KF, Karow ML, Rothenberg ME. The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia. J Immunol 2005;175:5341-5350. (Pubitemid 41456420)
    • (2005) Journal of Immunology , vol.175 , Issue.8 , pp. 5341-5350
    • Pope, S.M.1    Zimmermann, N.2    Stringer, K.F.3    Karow, M.L.4    Rothenberg, M.E.5
  • 44
    • 49249085467 scopus 로고    scopus 로고
    • Treatment with anti-CC chemokine receptor 3 monoclonal antibody or dexamethasone inhibits the migration and differentiation of bone marrow CD34 progenitor cells in an allergic mouse model
    • Ben S, Li X, Xu F, Xu W, Li W, Wu Z, Huang H, Shi H, Shen H. Treatment with anti-CC chemokine receptor 3 monoclonal antibody or dexamethasone inhibits the migration and differentiation of bone marrow CD34 progenitor cells in an allergic mouse model. Allergy 2008;63:1164-1176.
    • (2008) Allergy , vol.63 , pp. 1164-1176
    • Ben, S.1    Li, X.2    Xu, F.3    Xu, W.4    Li, W.5    Wu, Z.6    Huang, H.7    Shi, H.8    Shen, H.9
  • 46
    • 67649425653 scopus 로고    scopus 로고
    • Chemokine receptor antagonists: Part 1
    • Pease JE, Horuk R. Chemokine receptor antagonists: part 1. Expert Opin Ther Pat 2009;19:39-58.
    • (2009) Expert Opin Ther Pat , vol.19 , pp. 39-58
    • Pease, J.E.1    Horuk, R.2
  • 47
    • 77957200201 scopus 로고    scopus 로고
    • Small molecule antagonists for chemokine CCR3 receptors
    • Willems LI, Ijzerman AP. Small molecule antagonists for chemokine CCR3 receptors. Med Res Rev 2010;30:778-817.
    • (2010) Med Res Rev , vol.30 , pp. 778-817
    • Willems, L.I.1    Ijzerman, A.P.2
  • 54
    • 29144506755 scopus 로고    scopus 로고
    • The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells
    • Bachelet I, Munitz A, Moretta A, Moretta L, Levi-Schaffer F. The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells. J Immunol 2005;175:7989-7995. (Pubitemid 41798360)
    • (2005) Journal of Immunology , vol.175 , Issue.12 , pp. 7989-7995
    • Bachelet, I.1    Munitz, A.2    Moretta, A.3    Moretta, L.4    Levi-Schaffer, F.5
  • 55
    • 33750507499 scopus 로고    scopus 로고
    • Reversal of airway inflammation and remodeling in asthma by a bispecific antibody fragment linking CCR3 to CD300a
    • DOI 10.1016/j.jaci.2006.07.041, PII S0091674906015934
    • Munitz A, Bachelet I, Levi-Schaffer F. Reversal of airway inflammation and remodeling in asthma by a bispecific antibody fragment linking CCR3 to CD300a. J Allergy Clin Immunol 2006;118:1082-1089. (Pubitemid 44666985)
    • (2006) Journal of Allergy and Clinical Immunology , vol.118 , Issue.5 , pp. 1082-1089
    • Munitz, A.1    Bachelet, I.2    Levi-Schaffer, F.3
  • 59
    • 0029134144 scopus 로고
    • Molecular cloning and characterization of the human prostanoid DP receptor
    • Boie Y, Sawyer N, Slipetz DM, Metters KM, Abramovitz M. Molecular cloning and characterization of the human prostanoid DP receptor. J Biol Chem 1995;270:18910-18916.
    • (1995) J Biol Chem , vol.270 , pp. 18910-18916
    • Boie, Y.1    Sawyer, N.2    Slipetz, D.M.3    Metters, K.M.4    Abramovitz, M.5
  • 61
    • 0022388825 scopus 로고
    • Role of human basophils and mast cells in the pathogenesis of allergic diseases
    • DOI 10.1016/0091-6749(85)90656-6
    • Schleimer RP, Fox CC, Naclerio RM, Plaut M, Creticos PS, Togias AG, Warner JA, Kagey-Sobotka A, Lichtenstein LM. Role of human basophils and mast cells in the pathogenesis of allergic diseases. J Allergy Clin Immunol 1985;76:369-374. (Pubitemid 16247832)
    • (1985) Journal of Allergy and Clinical Immunology , vol.76 , Issue.SUPPL. 2II , pp. 369-374
    • Schleimer, R.P.1    Fox, C.C.2    Naclerio, R.M.3
  • 62
    • 0035883174 scopus 로고    scopus 로고
    • Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor
    • Monneret G, Gravel S, Diamond M, Rokach J, Powell WS. Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor. Blood 2001;200:1942-1948.
    • (2001) Blood , vol.200 , pp. 1942-1948
    • Monneret, G.1    Gravel, S.2    Diamond, M.3    Rokach, J.4    Powell, W.S.5
  • 65
    • 10744227854 scopus 로고    scopus 로고
    • 2, a Stable Thromboxane Metabolite, Is a Full Agonist of Chemoattractant Receptor-homologous Molecule Expressed on TH2 Cells (CRTH2) in Human Eosinophils and Basophils
    • DOI 10.1074/jbc.M310270200
    • Böhm E, Sturm GJ, Weiglhofer I, Sandig H, Shichijo M, McNamee A, Pease JE, Kollroser M, Peskar BA, Heinemann A. 11-Dehydrothromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. J Biol Chem 2004;279:7663-7670. (Pubitemid 38294647)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.9 , pp. 7663-7670
    • Bohm, E.1    Sturm, G.J.2    Weiglhofer, I.3    Sandig, H.4    Shichijo, M.5    McNamee, A.6    Pease, J.E.7    Kollroser, M.8    Peskar, B.A.9    Heinemann, A.10
  • 67
    • 0141920622 scopus 로고    scopus 로고
    • Genetic reprogramming of primary human T cells reveals functional plasticity in Th cell differentiation
    • Sundrud MS, Grill SM, Ni D, Nagata K, Alkan SS, Subramaniam A, Unutmaz D. Genetic reprogramming of primary human T cells reveals functional plasticity in Th cell differentiation. J Immunol 2003;171:3542-3549. (Pubitemid 37254556)
    • (2003) Journal of Immunology , vol.171 , Issue.7 , pp. 3542-3549
    • Sundrud, M.S.1    Grill, S.M.2    Ni, D.3    Nagata, K.4    Alkan, S.S.5    Subramaniam, A.6    Unutmaz, D.7
  • 72
    • 0030060019 scopus 로고    scopus 로고
    • 2 antagonist, reduces bronchial hyperresponsiveness in asthmatics
    • Aizawa H, Shigyo M, Nogami H, Hirose T, Hara N. BAY u3405, a thromboxane A2 antagonist, reduces bronchial hyperresponsiveness in asthmatics. Chest 1996;109:338-342. (Pubitemid 26058585)
    • (1996) Chest , vol.109 , Issue.2 , pp. 338-342
    • Aizawa, H.1    Shigyo, M.2    Nogami, H.3    Hirose, T.4    Hara, N.5
  • 76
    • 0025372112 scopus 로고
    • IgE-dependent antigen focusing by human B lymphocytes is mediated by the low-affinity receptor for IgE
    • DOI 10.1002/eji.1830200721
    • Pirron U, Schlunck T, Prinz JC, Rieber EP. IgE-dependent antigen focusing by human B lymphocytes is mediated by the low-affinity receptor for IgE. Eur J Immunol 1990;20:1547-1551. (Pubitemid 20233791)
    • (1990) European Journal of Immunology , vol.20 , Issue.7 , pp. 1547-1551
    • Pirron, U.1    Schlunck, T.2    Prinz, J.C.3    Rieber, E.P.4
  • 77
    • 0030852770 scopus 로고    scopus 로고
    • Induction of B cell apoptosis by co-cross-linking CD23 and sIg involves aberrant regulation of c-myc and is inhibited by bcl-2
    • DOI 10.1093/intimm/9.8.1131
    • Campbell KA, Studer EJ, Kilmon MA, Lees A, Finkelman F, Conrad DH. Induction of B cell apoptosis by co-cross-linking CD23 and sIg involves aberrant regulation of c-myc and is inhibited by bcl-2. Int Immunol 1997;9:1131-1140. (Pubitemid 27361756)
    • (1997) International Immunology , vol.9 , Issue.8 , pp. 1131-1140
    • Campbell, K.A.1    Studer, E.J.2    Kilmon, M.A.3    Lees, A.4    Finkelman, F.5    Conrad, D.H.6
  • 78
    • 0028167681 scopus 로고
    • Involvement of Fc epsilon RII/CD23 and L-arginine dependent pathway in IgE-mediated activation of human eosinophils
    • Arock M, Le Goff L, Bécherel PA, Dugas B, Debré P, Mossalayi MD. Involvement of Fc epsilon RII/CD23 and L-arginine dependent pathway in IgE-mediated activation of human eosinophils. Biochem Biophys Res Commun 1994;203:265-271.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 265-271
    • Arock, M.1    Le Goff, L.2    Bécherel, P.A.3    Dugas, B.4    Debré, P.5    Mossalayi, M.D.6
  • 79
    • 0034526888 scopus 로고    scopus 로고
    • Stimulation of eosinophil IgE low-affinity receptor leads to increased adhesion molecule expression and cell migration
    • Lantero S, Alessandri G, Spallarossa D, Scarso L, Rossi GA. Stimulation of eosinophil IgE low-affinity receptor leads to increased adhesion molecule expression and cell migration. Eur Respir J 2000;16:94094-94096.
    • (2000) Eur Respir J , vol.16 , pp. 94094-94096
    • Lantero, S.1    Alessandri, G.2    Spallarossa, D.3    Scarso, L.4    Rossi, G.A.5
  • 80
    • 0141736287 scopus 로고    scopus 로고
    • Inhibition of eosinophil transepithelial migration and downregulation of adhesion molecule expression on eosinophils and airway epithelial cells induced by budesonide
    • DOI 10.1006/pupt.2000.0228
    • Gonzalez Rodriguez R, Silvestri M, Cordone A, Salami A, Rossi GA. Inhibition of eosinophil transepithelial migration and downregulation of adhesion molecule expression on eosinophils and airway epithelial cells induced by budesonide. Pulm Pharmacol Ther 2000;13:31-38. (Pubitemid 30179526)
    • (2000) Pulmonary Pharmacology and Therapeutics , vol.13 , Issue.1 , pp. 31-38
    • Gonzalez, R.R.1    Silvestri, M.2    Cordone, A.3    Salami, A.4    Rossi, G.A.5
  • 81
    • 0034995829 scopus 로고    scopus 로고
    • Pulmonary T cells and eosinophils: Coconspirators or independent triggers of allergic respiratory pathology?
    • DOI 10.1067/mai.2001.116002
    • Lee NA, Gelfand EW, Lee JJ. Pulmonary T cells and eosinophils: coconspirators or independent triggers of allergic respiratory pathology? J Allergy Clin Immunol 2001;107:945-957. (Pubitemid 32523332)
    • (2001) Journal of Allergy and Clinical Immunology , vol.107 , Issue.6 , pp. 945-957
    • Lee, N.A.1    Gelfand, E.W.2    Lee, J.J.3
  • 82
    • 0028892985 scopus 로고
    • A reduction in allergen-induced Fc epsilon R2/CD23 expression on peripheral B cells correlates with successful hyposensitization in grass pollinosis
    • Jung CM, Prinz JC, Rieber EP, Ring J. A reduction in allergen-induced Fc epsilon R2/CD23 expression on peripheral B cells correlates with successful hyposensitization in grass pollinosis. J Allergy Clin Immunol 1995;95:77-87.
    • (1995) J Allergy Clin Immunol , vol.95 , pp. 77-87
    • Jung, C.M.1    Prinz, J.C.2    Rieber, E.P.3    Ring, J.4
  • 83
    • 0034509523 scopus 로고    scopus 로고
    • Increased sensitivity to IL-4 in patients with allergic bronchopulmonary aspergillosis
    • DOI 10.1159/000053644
    • Khan S, McClellan JS, Knutsen AP. Increased sensitivity to IL-4 in patients with allergic bronchopulmonary aspergillosis. Int Arch Allergy Immunol 2000;123:319-326. (Pubitemid 32037611)
    • (2000) International Archives of Allergy and Immunology , vol.123 , Issue.4 , pp. 319-326
    • Khan, S.1    McClellan, J.S.2    Knutsen, A.P.3
  • 84
    • 0036234602 scopus 로고    scopus 로고
    • Wasp venom rush immunotherapy induces transient downregulation of B cell surface molecule expression
    • DOI 10.1159/000053867
    • Roever AC, Henz BM, Worm M. Wasp venom rush immunotherapy induces transient downregulation of B cell surface molecule expression. Int Arch Allergy Immunol 2002;127:226-233. (Pubitemid 34455092)
    • (2002) International Archives of Allergy and Immunology , vol.127 , Issue.3 , pp. 226-233
    • Roever, A.C.1    Henz, B.M.2    Worm, M.3
  • 88
    • 25844461664 scopus 로고    scopus 로고
    • Anti-CD23 monoclonal antibody, lumiliximab, inhibited allergen-induced responses in antigen-presenting cells and T cells from atopic subjects
    • DOI 10.1016/j.jaci.2005.07.007, PII S0091674905016441
    • Poole JA, Meng J, Reff M, Spellman MC, Rosenwasser LJ. Anti-CD23 monoclonal antibody, lumiliximab, inhibited allergen-induced responses in antigen-presenting cells and T cells from atopic subjects. J Allergy Clin Immunol 2005;116:780-788. (Pubitemid 41400542)
    • (2005) Journal of Allergy and Clinical Immunology , vol.116 , Issue.4 , pp. 780-788
    • Poole, J.A.1    Meng, J.2    Reff, M.3    Spellman, M.C.4    Rosenwasser, L.J.5
  • 89
    • 0042736310 scopus 로고    scopus 로고
    • Allergic asthma and an anti-CD23 mAb (IDEC-152): Results of a phase I, single-dose, dose-escalating clinical trial
    • Rosenwasser LJ, Busse WW, Lizambri RG, Olejnik TA, Totoritis MC. Allergic asthma and an anti-CD23 mAb (IDEC-152): results of a phase I, single-dose, dose-escalating clinical trial. J Allergy Clin Immunol 2003;112:563-570.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 563-570
    • Rosenwasser, L.J.1    Busse, W.W.2    Lizambri, R.G.3    Olejnik, T.A.4    Totoritis, M.C.5
  • 90
    • 0031442143 scopus 로고    scopus 로고
    • Detection of a soluble form of the leukocyte surface antigen CD48 in plasma and its elevation in patients with lymphoid leukemias and arthritis
    • DOI 10.1023/A:1027327912204
    • Smith GM, Biggs J, Norris B, Anderson-Stewart P, Ward R. Detection of a soluble form of the leukocyte surface antigen CD48 in plasma and its elevation in patients with lymphoid leukemias and arthritis. J Clin Immunol 1997;17:502-509. (Pubitemid 28008109)
    • (1997) Journal of Clinical Immunology , vol.17 , Issue.6 , pp. 502-509
    • Smith, G.M.1    Biggs, J.2    Norris, B.3    Anderson-Stewart, P.4    Ward, R.5
  • 91
    • 0037207518 scopus 로고    scopus 로고
    • The dual-function CD 150 receptor subfamily: The viral attraction
    • DOI 10.1038/ni0103-19
    • Sidorenko SP, Clark EA. The dual-function CD150 receptor subfamily: the viral attraction. Nat Immunol 2003;4:19-24. (Pubitemid 36104703)
    • (2003) Nature Immunology , vol.4 , Issue.1 , pp. 19-24
    • Sidorenko, S.P.1    Clark, E.A.2
  • 92
    • 0032956398 scopus 로고    scopus 로고
    • Activating interactions in human NK cell recognition: The role of 2B4-CD48
    • DOI 10.1002/(SICI)1521-4141(199905)29:05<1676::AID-IMMU1676>3.0. CO;2-Y
    • Nakajima H, Cella M, Langen H, Friedlein A, Colonna M. Activating interactions in human NK cell recognition: the role of 2B4-CD48. Eur J Immunol 1999;29:1676-1683. (Pubitemid 29224473)
    • (1999) European Journal of Immunology , vol.29 , Issue.5 , pp. 1676-1683
    • Nakajima, H.1    Cella, M.2    Langen, H.3    Friedlein, A.4    Colonna, M.5
  • 97
    • 80053627653 scopus 로고    scopus 로고
    • Cytotoxic activity of CD48 monoclonal antibodies against human lymphoma cells
    • Wei J, Chin DY, Mahler SM. Cytotoxic activity of CD48 monoclonal antibodies against human lymphoma cells. Open Biotechnol J 2008;2:219-223.
    • (2008) Open Biotechnol J , vol.2 , pp. 219-223
    • Wei, J.1    Chin, D.Y.2    Mahler, S.M.3
  • 98
    • 0032956758 scopus 로고    scopus 로고
    • CD147 monoclonal antibodies induce homotypic cell aggregation of monocytic cell line U937 via LFA-1/ICAM-1 pathway
    • Kasinrerk W, Tokrasinwit N, Phunpae P. CD147 monoclonal antibodies induce homotypic cell aggregation of monocytic cell line U937 via LFA-1/ICAM-1 pathway. Immunology 1999;96:1841-1892.
    • (1999) Immunology , vol.96 , pp. 1841-1892
    • Kasinrerk, W.1    Tokrasinwit, N.2    Phunpae, P.3
  • 100
    • 33645064275 scopus 로고    scopus 로고
    • Dealing with the family: CD147 interactions with cyclophilins
    • Yurchenko V, Constant S, Bukrinsky M. Dealing with the family: CD147 interactions with cyclophilins. Immunology 2006;117:301-309.
    • (2006) Immunology , vol.117 , pp. 301-309
    • Yurchenko, V.1    Constant, S.2    Bukrinsky, M.3
  • 102
    • 0030936121 scopus 로고    scopus 로고
    • Presence of cyclophilin A in synovial fluids of patients with rheumatoid arthritis
    • DOI 10.1084/jem.185.5.975
    • Billich A, Winkler G, Aschauer H, Rot A, Peichl P. Presence of cyclophilin A in synovial fluids of patients with rheumatoid arthritis. J Exp Med 1997;185:975-980. (Pubitemid 27119882)
    • (1997) Journal of Experimental Medicine , vol.185 , Issue.5 , pp. 975-980
    • Billich, A.1    Winkler, G.2    Aschauer, H.3    Rot, A.4    Peichl, P.5
  • 105
    • 33947602811 scopus 로고    scopus 로고
    • Siglecs and their roles in the immune system
    • DOI 10.1038/nri2056, PII NRI2056
    • Crocker PR, Paulson JC, Varki A. Siglecs and their roles in the immune system. Nat Rev Immunol 2007;7:255-266. (Pubitemid 46480955)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.4 , pp. 255-266
    • Crocker, P.R.1    Paulson, J.C.2    Varki, A.3
  • 106
    • 0141992021 scopus 로고    scopus 로고
    • Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: Identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G)
    • DOI 10.1016/S0888-7543(03)00171-X
    • Aizawa H, Zimmermann N, Carrigan PE, Lee JJ, Rothenberg ME, Bochner BS. Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G). Genomics 2003;82:521-530. (Pubitemid 37239028)
    • (2003) Genomics , vol.82 , Issue.5 , pp. 521-530
    • Aizawa, H.1    Zimmermann, N.2    Carrigan, P.E.3    Lee, J.J.4    Rothenberg, M.E.5    Bochner, B.S.6
  • 107
    • 27944460432 scopus 로고    scopus 로고
    • Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6′-sulfo- sialyl Lewis X as a preferred glycan ligand
    • DOI 10.1093/glycob/cwi097
    • Tateno H, Crocker PR, Paulson JC. Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6′-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology 2005;15:1125-1135. (Pubitemid 41662639)
    • (2005) Glycobiology , vol.15 , Issue.11 , pp. 1125-1135
    • Tateno, H.1    Crocker, P.R.2    Paulson, J.C.3
  • 109
    • 0034613151 scopus 로고    scopus 로고
    • Immune inhibitory receptors
    • Ravetch JV, Lanier LL. Immune inhibitory receptors. Science 2000;290:84-89.
    • (2000) Science , vol.290 , pp. 84-89
    • Ravetch, J.V.1    Lanier, L.L.2
  • 110
    • 9144241714 scopus 로고    scopus 로고
    • The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by siglecs-7 and -9, CD33-related siglecs expressed on human monocytes and NK cells
    • Avril T, Floyd H, Lopez F, Vivier E, Crocker PR. The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by Siglecs-7 and -9, CD33-related Siglecs expressed on human monocytes and NK cells. J Immunol 2004;173:6841-6849. (Pubitemid 39541070)
    • (2004) Journal of Immunology , vol.173 , Issue.11 , pp. 6841-6849
    • Avril, T.1    Floyd, H.2    Lopez, F.3    Vivier, E.4    Crocker, P.R.5
  • 111
    • 0038044928 scopus 로고    scopus 로고
    • Ligation of Siglec-8: A selective mechanism for induction of human eosinophil apoptosis
    • Nutku E, Aizawa H, Hudson SA, Bochner BS. Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis. Blood 2003;101:5014-5020. (Pubitemid 36857767)
    • (2003) Blood , vol.101 , Issue.12 , pp. 5014-5020
    • Nutku, E.1    Aizawa, H.2    Hudson, S.A.3    Bochner, B.S.4
  • 112
    • 21644476233 scopus 로고    scopus 로고
    • Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment
    • DOI 10.1182/blood-2004-10-4112
    • von Gunten S, Yousefi S, Seitz M, Jakob SM, Schaffner T, Seger R, Takala J, Villiger PM, Simon HU. Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment. Blood 2005;106:1423-1431. (Pubitemid 41129611)
    • (2005) Blood , vol.106 , Issue.4 , pp. 1423-1431
    • Von Gunten, S.1    Yousefi, S.2    Seitz, M.3    Jakob, S.M.4    Schaffner, T.5    Seger, R.6    Takala, J.7    Villiger, P.M.8    Simon, H.-U.9
  • 113
    • 34248376987 scopus 로고    scopus 로고
    • Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils
    • DOI 10.1182/blood-2006-08-039255
    • Zhang M, Angata T, Cho JY, Miller M, Broide DH, Varki A. Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils. Blood 2007;109:4280-4287. (Pubitemid 46743394)
    • (2007) Blood , vol.109 , Issue.10 , pp. 4280-4287
    • Zhang, M.1    Angata, T.2    Jae, Y.C.3    Miller, M.4    Broide, D.H.5    Varki, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.