The pre-hydrolysis state of p21(ras) in complex with GTP: New insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins

Structure

Volumn 7, Issue 11, 1999, Pages 1311-1324

  Scheidig, Axel J ^a   Burmester, Christoph ^a   Goody, Roger S ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

Crystal structure; Freeze trapping; GTP binding protein; Hydrolysis mechanism; Reaction intermediate

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; PROTEIN P21; WATER;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HYDROLYSIS; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTON TRANSPORT; REACTION ANALYSIS; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

EID: 0033571343     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)80021-0     Document Type: Article

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