-
1
-
-
78650462753
-
Alzheimer's disease: a general introduction and pathomechanism
-
Finder V.H. Alzheimer's disease: a general introduction and pathomechanism. J Alzheimers Dis 2010, 22(Suppl. 3):5-19.
-
(2010)
J Alzheimers Dis
, vol.22
, Issue.SUPPL. 3
, pp. 5-19
-
-
Finder, V.H.1
-
2
-
-
67349143998
-
Classification and basic pathology of Alzheimer disease
-
Duyckaerts C., Delatour B., Potier M.C. Classification and basic pathology of Alzheimer disease. Acta Neuropathol 2009, 118(July (1)):5-36.
-
(2009)
Acta Neuropathol
, vol.118
, Issue.JULY 1
, pp. 5-36
-
-
Duyckaerts, C.1
Delatour, B.2
Potier, M.C.3
-
3
-
-
77955089472
-
Convergence of amyloid-beta and tau pathologies on mitochondria in vivo
-
Eckert A., Schulz K.L., Rhein V., Gotz J. Convergence of amyloid-beta and tau pathologies on mitochondria in vivo. Mol Neurobiol 2010, 41(June (2-3)):107-114.
-
(2010)
Mol Neurobiol
, vol.41
, Issue.JUNE 23
, pp. 107-114
-
-
Eckert, A.1
Schulz, K.L.2
Rhein, V.3
Gotz, J.4
-
4
-
-
58849143335
-
Accumulated amyloid-beta peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease
-
Huang H.C., Jiang Z.F. Accumulated amyloid-beta peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease. J Alzheimers Dis 2009, 16(1):15-27.
-
(2009)
J Alzheimers Dis
, vol.16
, Issue.1
, pp. 15-27
-
-
Huang, H.C.1
Jiang, Z.F.2
-
5
-
-
77952556970
-
The biochemical study on the etiology of Alzheimer's disease
-
Imahori K. The biochemical study on the etiology of Alzheimer's disease. Proc Jpn Acad Ser B Phys Biol Sci 2010, 86(1):54-61.
-
(2010)
Proc Jpn Acad Ser B Phys Biol Sci
, vol.86
, Issue.1
, pp. 54-61
-
-
Imahori, K.1
-
6
-
-
77953499350
-
The revitalized tau hypothesis on Alzheimer's disease
-
Maccioni R.B., Farias G., Morales I., Navarrete L. The revitalized tau hypothesis on Alzheimer's disease. Arch Med Res 2010, 41(April (3)):226-231.
-
(2010)
Arch Med Res
, vol.41
, Issue.APRIL 3
, pp. 226-231
-
-
Maccioni, R.B.1
Farias, G.2
Morales, I.3
Navarrete, L.4
-
7
-
-
56349119351
-
Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis
-
Small S.A., Duff K. Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis. Neuron 2008, 60(November (4)):534-542.
-
(2008)
Neuron
, vol.60
, Issue.NOVEMBER 4
, pp. 534-542
-
-
Small, S.A.1
Duff, K.2
-
8
-
-
47949132196
-
Active and passive immunotherapy for neurodegenerative disorders
-
Brody D.L., Holtzman D.M. Active and passive immunotherapy for neurodegenerative disorders. Annu Rev Neurosci 2008, 31:175-193.
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 175-193
-
-
Brody, D.L.1
Holtzman, D.M.2
-
9
-
-
9644272528
-
Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease
-
Chauhan N.B., Siegel G.J. Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease. Expert Rev Vaccines 2004, 3(December (6)):717-725.
-
(2004)
Expert Rev Vaccines
, vol.3
, Issue.DECEMBER 6
, pp. 717-725
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
10
-
-
53749096936
-
Amyloid-beta vaccination for Alzheimer's dementia
-
author reply - 2
-
Holtzman J.L. Amyloid-beta vaccination for Alzheimer's dementia. Lancet 2008, 372(October (9647)):1381. author reply - 2.
-
(2008)
Lancet
, vol.372
, Issue.OCTOBER 9647
, pp. 1381
-
-
Holtzman, J.L.1
-
11
-
-
34548685847
-
Novel Abeta immunogens: is shorter better?
-
Lemere C.A., Maier M., Peng Y., Jiang L., Seabrook T.J. Novel Abeta immunogens: is shorter better?. Curr Alzheimer Res 2007, 4(September (4)):427-436.
-
(2007)
Curr Alzheimer Res
, vol.4
, Issue.SEPTEMBER 4
, pp. 427-436
-
-
Lemere, C.A.1
Maier, M.2
Peng, Y.3
Jiang, L.4
Seabrook, T.J.5
-
12
-
-
53749108464
-
Amyloid-beta vaccination for Alzheimer's dementia
-
author reply - 2
-
McGeer P.L. Amyloid-beta vaccination for Alzheimer's dementia. Lancet 2008, 372(October (9647)):1381. author reply - 2.
-
(2008)
Lancet
, vol.372
, Issue.OCTOBER 9647
, pp. 1381
-
-
McGeer, P.L.1
-
13
-
-
33744471433
-
A beta immunotherapy: lessons learned for potential treatment of Alzheimer's disease
-
Schenk D.B., Seubert P., Grundman M., Black R. A beta immunotherapy: lessons learned for potential treatment of Alzheimer's disease. Neurodegener Dis 2005, 2(5):255-260.
-
(2005)
Neurodegener Dis
, vol.2
, Issue.5
, pp. 255-260
-
-
Schenk, D.B.1
Seubert, P.2
Grundman, M.3
Black, R.4
-
14
-
-
48949085739
-
Amyloid-beta immunisation for Alzheimer's disease
-
Wisniewski T., Konietzko U. Amyloid-beta immunisation for Alzheimer's disease. Lancet Neurol 2008, 7(September (9)):805-811.
-
(2008)
Lancet Neurol
, vol.7
, Issue.SEPTEMBER 9
, pp. 805-811
-
-
Wisniewski, T.1
Konietzko, U.2
-
15
-
-
57649134261
-
Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease
-
Hanson L.R., Frey W.H. Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease. BMC Neurosci 2008, 9(Suppl. 3):S5.
-
(2008)
BMC Neurosci
, vol.9
, Issue.SUPPL. 3
-
-
Hanson, L.R.1
Frey, W.H.2
-
16
-
-
0037459005
-
Nasal drug delivery - possibilities, problems and solutions
-
Illum L. Nasal drug delivery - possibilities, problems and solutions. J Control Release 2003, 87(February (1-3)):187-198.
-
(2003)
J Control Release
, vol.87
, Issue.FEBRUARY 13
, pp. 187-198
-
-
Illum, L.1
-
17
-
-
0035984813
-
Drug transport into the mammalian brain: the nasal pathway and its specific metabolic barrier
-
Minn A., Leclerc S., Heydel J.M., Minn A.L., Denizcot C., Cattarelli M., et al. Drug transport into the mammalian brain: the nasal pathway and its specific metabolic barrier. J Drug Target 2002, 10(June (4)):285-296.
-
(2002)
J Drug Target
, vol.10
, Issue.JUNE 4
, pp. 285-296
-
-
Minn, A.1
Leclerc, S.2
Heydel, J.M.3
Minn, A.L.4
Denizcot, C.5
Cattarelli, M.6
-
18
-
-
3542998669
-
Nasal route and drug delivery systems
-
Turker S., Onur E., Ozer Y. Nasal route and drug delivery systems. Pharm World Sci 2004, 26(June (3)):137-142.
-
(2004)
Pharm World Sci
, vol.26
, Issue.JUNE 3
, pp. 137-142
-
-
Turker, S.1
Onur, E.2
Ozer, Y.3
-
19
-
-
3242740239
-
Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration
-
Thorne R.G., Pronk G.J., Padmanabhan V., Frey W.H. Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration. Neuroscience 2004, 127(2):481-496.
-
(2004)
Neuroscience
, vol.127
, Issue.2
, pp. 481-496
-
-
Thorne, R.G.1
Pronk, G.J.2
Padmanabhan, V.3
Frey, W.H.4
-
20
-
-
0035693963
-
Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations
-
Thorne R.G., Frey W.H. Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations. Clin Pharmacokinet 2001, 40(12):907-946.
-
(2001)
Clin Pharmacokinet
, vol.40
, Issue.12
, pp. 907-946
-
-
Thorne, R.G.1
Frey, W.H.2
-
21
-
-
33846848061
-
Strategies for intranasal delivery of therapeutics for the prevention and treatment of neuroAIDS
-
Hanson L.R., Frey W.H. Strategies for intranasal delivery of therapeutics for the prevention and treatment of neuroAIDS. J Neuroimmune Pharmacol 2007, 2(March (1)):81-86.
-
(2007)
J Neuroimmune Pharmacol
, vol.2
, Issue.MARCH 1
, pp. 81-86
-
-
Hanson, L.R.1
Frey, W.H.2
-
22
-
-
34547655840
-
Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration
-
Gao X., Wu B., Zhang Q., Chen J., Zhu J., Zhang W., et al. Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration. J Control Release 2007, 121(August (3)):156-167.
-
(2007)
J Control Release
, vol.121
, Issue.AUGUST 3
, pp. 156-167
-
-
Gao, X.1
Wu, B.2
Zhang, Q.3
Chen, J.4
Zhu, J.5
Zhang, W.6
-
23
-
-
0031964794
-
Prophylactic administration of a complementarity-determining region derived from a neutralizing monoclonal antibody is effective against respiratory syncytial virus infection in BALB/c mice
-
Bourgeois C., Bour J.B., Aho L.S., Pothier P. Prophylactic administration of a complementarity-determining region derived from a neutralizing monoclonal antibody is effective against respiratory syncytial virus infection in BALB/c mice. J Virol 1998, 72(January (1)):807-810.
-
(1998)
J Virol
, vol.72
, Issue.JANUARY 1
, pp. 807-810
-
-
Bourgeois, C.1
Bour, J.B.2
Aho, L.S.3
Pothier, P.4
-
24
-
-
0036178014
-
Passive intranasal monoclonal antibody prophylaxis against murine Pneumocystis carinii pneumonia
-
Gigliotti F., Haidaris C.G., Wright T.W., Harmsen A.G. Passive intranasal monoclonal antibody prophylaxis against murine Pneumocystis carinii pneumonia. Infect Immun 2002, 70(March (3)):1069-1074.
-
(2002)
Infect Immun
, vol.70
, Issue.MARCH 3
, pp. 1069-1074
-
-
Gigliotti, F.1
Haidaris, C.G.2
Wright, T.W.3
Harmsen, A.G.4
-
25
-
-
33645013856
-
Lectin-conjugated PEG-PLA nanoparticles: preparation and brain delivery after intranasal administration
-
Gao X., Tao W., Lu W., Zhang Q., Zhang Y., Jiang X., et al. Lectin-conjugated PEG-PLA nanoparticles: preparation and brain delivery after intranasal administration. Biomaterials 2006, 27(June (18)):3482-3490.
-
(2006)
Biomaterials
, vol.27
, Issue.JUNE 18
, pp. 3482-3490
-
-
Gao, X.1
Tao, W.2
Lu, W.3
Zhang, Q.4
Zhang, Y.5
Jiang, X.6
-
26
-
-
0029026040
-
Quantitative analysis of the olfactory pathway for drug delivery to the brain
-
Thorne R.G., Emory C.R., Ala T.A., Frey W.H. Quantitative analysis of the olfactory pathway for drug delivery to the brain. Brain Res 1995, 692(September (1-2)):278-282.
-
(1995)
Brain Res
, vol.692
, Issue.SEPTEMBER 12
, pp. 278-282
-
-
Thorne, R.G.1
Emory, C.R.2
Ala, T.A.3
Frey, W.H.4
-
27
-
-
33749521100
-
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation
-
Oakley H., Cole S.L., Logan S., Maus E., Shao P., Craft J., et al. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J Neurosci 2006, 26(October (40)):10129-10140.
-
(2006)
J Neurosci
, vol.26
, Issue.OCTOBER 40
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
Logan, S.3
Maus, E.4
Shao, P.5
Craft, J.6
-
28
-
-
0035888264
-
Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain
-
Chauhan N.B., Siegel G.J., Lichtor T. Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain. J Neurosci Res 2001, 66(October (2)):231-235.
-
(2001)
J Neurosci Res
, vol.66
, Issue.OCTOBER 2
, pp. 231-235
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lichtor, T.3
-
29
-
-
45249108473
-
Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses
-
Cerpa W., Dinamarca M.C., Inestrosa N.C. Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses. Curr Alzheimer Res 2008, 5(June (3)):233-243.
-
(2008)
Curr Alzheimer Res
, vol.5
, Issue.JUNE 3
, pp. 233-243
-
-
Cerpa, W.1
Dinamarca, M.C.2
Inestrosa, N.C.3
-
30
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R., Bennett B.D., Babu-Khan S., Kahn S., Mendiaz E.A., Denis P., et al. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 1999, 286(October (5440)):735-741.
-
(1999)
Science
, vol.286
, Issue.OCTOBER 5440
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
-
31
-
-
0035979234
-
Presenilin-dependent gamma-secretase activity modulates thymocyte development
-
Doerfler P., Shearman M.S., Perlmutter R.M. Presenilin-dependent gamma-secretase activity modulates thymocyte development. Proc Natl Acad Sci U S A 2001, 98(July (16)):9312-9317.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.JULY 16
, pp. 9312-9317
-
-
Doerfler, P.1
Shearman, M.S.2
Perlmutter, R.M.3
-
32
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity
-
Weggen S., Eriksen J.L., Das P., Sagi S.A., Wang R., Pietrzik C.U., et al. A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature 2001, 414(November (6860)):212-216.
-
(2001)
Nature
, vol.414
, Issue.NOVEMBER 6860
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.L.2
Das, P.3
Sagi, S.A.4
Wang, R.5
Pietrzik, C.U.6
-
33
-
-
0042970733
-
Role of acetylcholinesterase inhibitors in the metabolism of amyloid precursor protein
-
Pakaski M., Kasa P. Role of acetylcholinesterase inhibitors in the metabolism of amyloid precursor protein. Curr Drug Targets CNS Neurol Disord 2003, 2(June (3)):163-171.
-
(2003)
Curr Drug Targets CNS Neurol Disord
, vol.2
, Issue.JUNE 3
, pp. 163-171
-
-
Pakaski, M.1
Kasa, P.2
-
34
-
-
12444313989
-
Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease
-
Hock C., Maddalena A., Raschig A., Muller-Spahn F., Eschweiler G., Hager K., et al. Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease. Amyloid 2003, 10(March (1)):1-6.
-
(2003)
Amyloid
, vol.10
, Issue.MARCH 1
, pp. 1-6
-
-
Hock, C.1
Maddalena, A.2
Raschig, A.3
Muller-Spahn, F.4
Eschweiler, G.5
Hager, K.6
-
35
-
-
0037390039
-
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo
-
Farris W., Mansourian S., Chang Y., Lindsley L., Eckman E.A., Frosch M.P., et al. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc Natl Acad Sci U S A 2003, 100(April (7)):4162-4167.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.APRIL 7
, pp. 4162-4167
-
-
Farris, W.1
Mansourian, S.2
Chang, Y.3
Lindsley, L.4
Eckman, E.A.5
Frosch, M.P.6
-
36
-
-
0037462769
-
Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme
-
Eckman E.A., Watson M., Marlow L., Sambamurti K., Eckman C.B. Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme. J Biol Chem 2003, 278(January (4)):2081-2084.
-
(2003)
J Biol Chem
, vol.278
, Issue.JANUARY 4
, pp. 2081-2084
-
-
Eckman, E.A.1
Watson, M.2
Marlow, L.3
Sambamurti, K.4
Eckman, C.B.5
-
37
-
-
18544410708
-
The plasmin system is induced by and degrades amyloid-beta aggregates
-
Tucker H.M., Kihiko M., Caldwell J.N., Wright S., Kawarabayashi T., Price D., et al. The plasmin system is induced by and degrades amyloid-beta aggregates. J Neurosci 2000, 20(June (11)):3937-3946.
-
(2000)
J Neurosci
, vol.20
, Issue.JUNE 11
, pp. 3937-3946
-
-
Tucker, H.M.1
Kihiko, M.2
Caldwell, J.N.3
Wright, S.4
Kawarabayashi, T.5
Price, D.6
-
38
-
-
0035947207
-
Metabolic regulation of brain Abeta by neprilysin
-
Iwata N., Tsubuki S., Takaki Y., Shirotani K., Lu B., Gerard N.P., et al. Metabolic regulation of brain Abeta by neprilysin. Science 2001, 292(May (5521)):1550-1552.
-
(2001)
Science
, vol.292
, Issue.MAY 5521
, pp. 1550-1552
-
-
Iwata, N.1
Tsubuki, S.2
Takaki, Y.3
Shirotani, K.4
Lu, B.5
Gerard, N.P.6
-
39
-
-
0027980901
-
Rapid induction of Alzheimer A beta amyloid formation by zinc
-
Bush A.I., Pettingell W.H., Multhaup G., d Paradis M., Vonsattel J.P., Gusella J.F., et al. Rapid induction of Alzheimer A beta amyloid formation by zinc. Science 1994, 265(September (5177)):1464-1467.
-
(1994)
Science
, vol.265
, Issue.SEPTEMBER 5177
, pp. 1464-1467
-
-
Bush, A.I.1
Pettingell, W.H.2
Multhaup, G.3
d Paradis, M.4
Vonsattel, J.P.5
Gusella, J.F.6
-
40
-
-
0034964390
-
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice
-
Cherny R.A., Atwood C.S., Xilinas M.E., Gray D.N., Jones W.D., McLean C.A., et al. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron 2001, 30(June (3)):665-676.
-
(2001)
Neuron
, vol.30
, Issue.JUNE 3
, pp. 665-676
-
-
Cherny, R.A.1
Atwood, C.S.2
Xilinas, M.E.3
Gray, D.N.4
Jones, W.D.5
McLean, C.A.6
-
41
-
-
10744224267
-
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial
-
Ritchie C.W., Bush A.I., Mackinnon A., Macfarlane S., Mastwyk M., MacGregor L., et al. Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch Neurol 2003, 60(December (12)):1685-1691.
-
(2003)
Arch Neurol
, vol.60
, Issue.DECEMBER 12
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
Mackinnon, A.3
Macfarlane, S.4
Mastwyk, M.5
MacGregor, L.6
-
42
-
-
33746649088
-
Anti-amyloidogenic therapies: strategies for prevention and treatment of Alzheimer's disease
-
Hamaguchi T., Ono K., Yamada M. Anti-amyloidogenic therapies: strategies for prevention and treatment of Alzheimer's disease. Cell Mol Life Sci 2006, 63(July (13)):1538-1552.
-
(2006)
Cell Mol Life Sci
, vol.63
, Issue.JULY 13
, pp. 1538-1552
-
-
Hamaguchi, T.1
Ono, K.2
Yamada, M.3
-
43
-
-
0036780877
-
Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning
-
Schenk D. Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning. Nat Rev Neurosci 2002, 3(October (10)):824-828.
-
(2002)
Nat Rev Neurosci
, vol.3
, Issue.OCTOBER 10
, pp. 824-828
-
-
Schenk, D.1
-
44
-
-
31544482664
-
[Abeta vaccine therapy for Alzheimer's disease]
-
Hara H. [Abeta vaccine therapy for Alzheimer's disease]. Rinsho Shinkeigaku 2005, 45(November (11)):867-869.
-
(2005)
Rinsho Shinkeigaku
, vol.45
, Issue.NOVEMBER 11
, pp. 867-869
-
-
Hara, H.1
-
45
-
-
0033801852
-
Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease
-
Weiner H.L., Lemere C.A., Maron R., Spooner E.T., Grenfell T.J., Mori C., et al. Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease. Ann Neurol 2000, 48(October (4)):567-579.
-
(2000)
Ann Neurol
, vol.48
, Issue.OCTOBER 4
, pp. 567-579
-
-
Weiner, H.L.1
Lemere, C.A.2
Maron, R.3
Spooner, E.T.4
Grenfell, T.J.5
Mori, C.6
-
46
-
-
0034700471
-
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus C., Pearson J., McLaurin J., Mathews P.M., Jiang Y., Schmidt S.D., et al. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 2000, 408(December (6815)):979-982.
-
(2000)
Nature
, vol.408
, Issue.DECEMBER 6815
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
-
47
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D., Diamond D.M., Gottschall P.E., Ugen K.E., Dickey C., Hardy J., et al. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 2000, 408(December (6815)):982-985.
-
(2000)
Nature
, vol.408
, Issue.DECEMBER 6815
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
-
48
-
-
0034746897
-
Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition
-
Das P., Murphy M.P., Younkin L.H., Younkin S.G., Golde T.E. Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition. Neurobiol Aging 2001, 22(September-October (5)):721-727.
-
(2001)
Neurobiol Aging
, vol.22
, Issue.SEPTEMBER OCTOBER 5
, pp. 721-727
-
-
Das, P.1
Murphy, M.P.2
Younkin, L.H.3
Younkin, S.G.4
Golde, T.E.5
-
49
-
-
0034884382
-
Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
-
Sigurdsson E.M., Scholtzova H., Mehta P.D., Frangione B., Wisniewski T. Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am J Pathol 2001, 159(August (2)):439-447.
-
(2001)
Am J Pathol
, vol.159
, Issue.AUGUST 2
, pp. 439-447
-
-
Sigurdsson, E.M.1
Scholtzova, H.2
Mehta, P.D.3
Frangione, B.4
Wisniewski, T.5
-
50
-
-
0034633632
-
Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administration
-
Frenkel D., Katz O., Solomon B. Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administration. Proc Natl Acad Sci U S A 2000, 97(October (21)):11455-11459.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.OCTOBER 21
, pp. 11455-11459
-
-
Frenkel, D.1
Katz, O.2
Solomon, B.3
-
51
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F., Cannon C., Barbour R., Burke R.L., Games D., Grajeda H., et al. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med 2000, 6(August (8)):916-919.
-
(2000)
Nat Med
, vol.6
, Issue.AUGUST 8
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
-
52
-
-
0035902619
-
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
-
DeMattos R.B., Bales K.R., Cummins D.J., Dodart J.C., Paul S.M., Holtzman D.M. Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 2001, 98(July (15)):8850-8855.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.JULY 15
, pp. 8850-8855
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.C.4
Paul, S.M.5
Holtzman, D.M.6
-
53
-
-
0036914592
-
Immunological approaches as therapy for Alzheimer's disease
-
Solomon B. Immunological approaches as therapy for Alzheimer's disease. Expert Opin Biol Ther 2002, 2(December (8)):907-917.
-
(2002)
Expert Opin Biol Ther
, vol.2
, Issue.DECEMBER 8
, pp. 907-917
-
-
Solomon, B.1
-
54
-
-
0035695315
-
Immunotherapeutic strategies for prevention and treatment of Alzheimer's disease
-
Solomon B. Immunotherapeutic strategies for prevention and treatment of Alzheimer's disease. DNA Cell Biol 2001, 20(November (11)):697-703.
-
(2001)
DNA Cell Biol
, vol.20
, Issue.NOVEMBER 11
, pp. 697-703
-
-
Solomon, B.1
-
55
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
-
Dodart J.C., Bales K.R., Gannon K.S., Greene S.J., DeMattos R.B., Mathis C., et al. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nat Neurosci 2002, 5(May (5)):452-457.
-
(2002)
Nat Neurosci
, vol.5
, Issue.MAY 5
, pp. 452-457
-
-
Dodart, J.C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
DeMattos, R.B.5
Mathis, C.6
-
56
-
-
0037031861
-
Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation
-
Mohajeri M.H., Saini K., Schultz J.G., Wollmer M.A., Hock C., Nitsch R.M. Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation. J Biol Chem 2002, 277(September (36)):33012-33017.
-
(2002)
J Biol Chem
, vol.277
, Issue.SEPTEMBER 36
, pp. 33012-33017
-
-
Mohajeri, M.H.1
Saini, K.2
Schultz, J.G.3
Wollmer, M.A.4
Hock, C.5
Nitsch, R.M.6
-
57
-
-
0038100154
-
Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease
-
Hock C., Konietzko U., Streffer J.R., Tracy J., Signorell A., Muller-Tillmanns B., et al. Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease. Neuron 2003, 38(May (4)):547-554.
-
(2003)
Neuron
, vol.38
, Issue.MAY 4
, pp. 547-554
-
-
Hock, C.1
Konietzko, U.2
Streffer, J.R.3
Tracy, J.4
Signorell, A.5
Muller-Tillmanns, B.6
-
58
-
-
0037112201
-
Cerebral hemorrhage after passive anti-Abeta immunotherapy
-
Pfeifer M., Boncristiano S., Bondolfi L., Stalder A., Deller T., Staufenbiel M., et al. Cerebral hemorrhage after passive anti-Abeta immunotherapy. Science 2002, 298(November (5597)):1379.
-
(2002)
Science
, vol.298
, Issue.NOVEMBER 5597
, pp. 1379
-
-
Pfeifer, M.1
Boncristiano, S.2
Bondolfi, L.3
Stalder, A.4
Deller, T.5
Staufenbiel, M.6
-
59
-
-
77956229704
-
Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis
-
Boche D., Denham N., Holmes C., Nicoll J.A. Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis. Acta Neuropathol 2010, 120(September (3)):369-384.
-
(2010)
Acta Neuropathol
, vol.120
, Issue.SEPTEMBER 3
, pp. 369-384
-
-
Boche, D.1
Denham, N.2
Holmes, C.3
Nicoll, J.A.4
-
60
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report
-
Nicoll J.A., Wilkinson D., Holmes C., Steart P., Markham H., Weller R.O. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med 2003, 9(April (4)):448-452.
-
(2003)
Nat Med
, vol.9
, Issue.APRIL 4
, pp. 448-452
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
61
-
-
77951920630
-
Cerebral amyloid angiopathy and microhemorrhages after amyloid beta vaccination: case report and brief review
-
Uro-Coste E., Russano de Paiva G., Guilbeau-Frugier C., Sastre N., Ousset P.J., da Silva N.A., et al. Cerebral amyloid angiopathy and microhemorrhages after amyloid beta vaccination: case report and brief review. Clin Neuropathol 2010, 29(July-August (4)):209-216.
-
(2010)
Clin Neuropathol
, vol.29
, Issue.JULY AUGUST 4
, pp. 209-216
-
-
Uro-Coste, E.1
Russano de Paiva, G.2
Guilbeau-Frugier, C.3
Sastre, N.4
Ousset, P.J.5
da Silva, N.A.6
-
62
-
-
18144380723
-
Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis
-
Lee E.B., Leng L.Z., Lee V.M., Trojanowski J.Q. Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis. FEBS Lett 2005, 579(May (12)):2564-2568.
-
(2005)
FEBS Lett
, vol.579
, Issue.MAY 12
, pp. 2564-2568
-
-
Lee, E.B.1
Leng, L.Z.2
Lee, V.M.3
Trojanowski, J.Q.4
-
63
-
-
33744982670
-
Modulation of microglial activation state following passive immunization in amyloid depositing transgenic mice
-
Morgan D. Modulation of microglial activation state following passive immunization in amyloid depositing transgenic mice. Neurochem Int 2006, 49(July (2)):190-194.
-
(2006)
Neurochem Int
, vol.49
, Issue.JULY 2
, pp. 190-194
-
-
Morgan, D.1
-
64
-
-
77957167389
-
Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Abeta/amyloid burden in a transgenic mouse model of Alzheimer's disease
-
Minami S.S., Sidahmed E., Aid S., Shimoji M., Niikura T., Mocchetti I., et al. Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Abeta/amyloid burden in a transgenic mouse model of Alzheimer's disease. J Neuroinflamm 2010, 7:57.
-
(2010)
J Neuroinflamm
, vol.7
, pp. 57
-
-
Minami, S.S.1
Sidahmed, E.2
Aid, S.3
Shimoji, M.4
Niikura, T.5
Mocchetti, I.6
-
65
-
-
0036644989
-
Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody
-
Chauhan N.B., Siegel G.J. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. J Neurosci Res 2002, 69(July (1)):10-23.
-
(2002)
J Neurosci Res
, vol.69
, Issue.JULY 1
, pp. 10-23
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
66
-
-
0141758165
-
Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576
-
Chauhan N.B., Siegel G.J. Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576. J Neurosci Res 2003, 74(October (1)):142-147.
-
(2003)
J Neurosci Res
, vol.74
, Issue.OCTOBER 1
, pp. 142-147
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
67
-
-
9644305699
-
Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Abeta antibody into the third ventricle of TgCRND8 mice
-
Chauhan N.B., Siegel G.J., Lichtor T. Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Abeta antibody into the third ventricle of TgCRND8 mice. J Neurosci Res 2004, 78(December (5)):732-741.
-
(2004)
J Neurosci Res
, vol.78
, Issue.DECEMBER 5
, pp. 732-741
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lichtor, T.3
-
68
-
-
0035106780
-
Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
-
Bacskai B.J., Kajdasz S.T., Christie R.H., Carter C., Games D., Seubert P., et al. Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat Med 2001, 7(March (3)):369-372.
-
(2001)
Nat Med
, vol.7
, Issue.MARCH 3
, pp. 369-372
-
-
Bacskai, B.J.1
Kajdasz, S.T.2
Christie, R.H.3
Carter, C.4
Games, D.5
Seubert, P.6
-
69
-
-
0036484536
-
Towards Alzheimer's disease vaccination
-
Solomon B. Towards Alzheimer's disease vaccination. Mini Rev Med Chem 2002, 2(February (1)):85-92.
-
(2002)
Mini Rev Med Chem
, vol.2
, Issue.FEBRUARY 1
, pp. 85-92
-
-
Solomon, B.1
-
70
-
-
14844327972
-
Generation of anti-beta-amyloid antibodies via phage display technology towards Alzheimer's disease vaccination
-
Solomon B. Generation of anti-beta-amyloid antibodies via phage display technology towards Alzheimer's disease vaccination. Vaccine 2005, 23(March (17-18)):2327-2330.
-
(2005)
Vaccine
, vol.23
, Issue.MARCH 1718
, pp. 2327-2330
-
-
Solomon, B.1
-
71
-
-
84880189661
-
Alzheimer's disease immunotherapy: from in vitro amyloid immunomodulation to in vivo vaccination
-
Solomon B. Alzheimer's disease immunotherapy: from in vitro amyloid immunomodulation to in vivo vaccination. J Alzheimers Dis 2006, 9(Suppl. 3):433-438.
-
(2006)
J Alzheimers Dis
, vol.9
, Issue.SUPPL. 3
, pp. 433-438
-
-
Solomon, B.1
-
72
-
-
13444283725
-
Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8
-
Chauhan N.B., Siegel G.J. Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8. Neurosci Lett 2005, 375(March (3)):143-147.
-
(2005)
Neurosci Lett
, vol.375
, Issue.MARCH 3
, pp. 143-147
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
73
-
-
33846861744
-
Intracerebroventricular passive immunization with anti-oligoAbeta antibody in TgCRND8
-
Chauhan N.B. Intracerebroventricular passive immunization with anti-oligoAbeta antibody in TgCRND8. J Neurosci Res 2007, 85(February (2)):451-463.
-
(2007)
J Neurosci Res
, vol.85
, Issue.FEBRUARY 2
, pp. 451-463
-
-
Chauhan, N.B.1
|