-
1
-
-
0002503154
-
Beta-amyloid peptides as direct cholinergic neuromodulators: A missing link?
-
Auld DS, Kar S, Quirion R. 1998. Beta-amyloid peptides as direct cholinergic neuromodulators: a missing link? Trends Neurosci 21:43-49.
-
(1998)
Trends Neurosci
, vol.21
, pp. 43-49
-
-
Auld, D.S.1
Kar, S.2
Quirion, R.3
-
2
-
-
0036810329
-
Alzheimer's disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies
-
Auld DS, Kornecook TJ, Bastianetto S, Quirion R. 2002. Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies. Prog Neurobiol 68:209-245.
-
(2002)
Prog Neurobiol
, vol.68
, pp. 209-245
-
-
Auld, D.S.1
Kornecook, T.J.2
Bastianetto, S.3
Quirion, R.4
-
3
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer's disease
-
Bard F, Cannon C, Barbour R, Burke RL, Games D, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Lieberburg I, Motter R, Nguyen M, Soriano F, Vasquez N, Weiss K, Welch B, Seubert P, Schenk D, Yednock T. 2000. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer's disease. Nat Med 6:916-919.
-
(2000)
Nat Med
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, M.13
Lieberburg, I.14
Motter, R.15
Nguyen, M.16
Soriano, F.17
Vasquez, N.18
Weiss, K.19
Welch, B.20
Seubert, P.21
Schenk, D.22
Yednock, T.23
more..
-
4
-
-
0036905921
-
Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: Implications for neurodegeneration in Alzheimer's disease brain
-
Butterfield DA. 2002. Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. Free Radic Res 36:1307-1313.
-
(2002)
Free Radic Res
, vol.36
, pp. 1307-1313
-
-
Butterfield, D.A.1
-
5
-
-
0037115049
-
Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation
-
Buttini M, Yu GQ, Shockley K, Huang Y, Jones B, Masliah E, Mallory M, Yeo T, Longo FM, Mucke L. 2002. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation. J Neurosci 22:10539-10548.
-
(2002)
J Neurosci
, vol.22
, pp. 10539-10548
-
-
Buttini, M.1
Yu, G.Q.2
Shockley, K.3
Huang, Y.4
Jones, B.5
Masliah, E.6
Mallory, M.7
Yeo, T.8
Longo, F.M.9
Mucke, L.10
-
6
-
-
1542377619
-
Toxicity of amyloid beta peptide: Tales of calcium, mitochondria, and oxidative stress
-
Canevari L, Abramov AY, Duchen MR. 2004. Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress. Neurochem Res 29:637-650.
-
(2004)
Neurochem Res
, vol.29
, pp. 637-650
-
-
Canevari, L.1
Abramov, A.Y.2
Duchen, M.R.3
-
7
-
-
18244399344
-
Pathophysiologjcal roles of amyloidogenic carboxy-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease
-
Chang KA, Suh YH. 2005. Pathophysiologjcal roles of amyloidogenic carboxy-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease. J Pharmacol Sci 97:461-471.
-
(2005)
J Pharmacol Sci
, vol.97
, pp. 461-471
-
-
Chang, K.A.1
Suh, Y.H.2
-
8
-
-
0036644989
-
Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody
-
Chauhan NB, Siegel GJ. 2002. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. J Neurosci Res 69:10-23.
-
(2002)
J Neurosci Res
, vol.69
, pp. 10-23
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
9
-
-
0141758165
-
Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576
-
Chauhan NB, Siegel GJ. 2003a. Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576. J Neurosci Res 74:142-147.
-
(2003)
J Neurosci Res
, vol.74
, pp. 142-147
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
10
-
-
0037411794
-
Effect of PPF and ALCAR on the induction of NGF- and p75-mRNA and on APP processing in Tg2576 brain
-
Chauhan NB, Siegel GJ. 2003b. Effect of PPF and ALCAR on the induction of NGF- and p75-mRNA and on APP processing in Tg2576 brain. Neurochem Int 43:225-233.
-
(2003)
Neurochem Int
, vol.43
, pp. 225-233
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
11
-
-
9644272528
-
Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease
-
Chauhan NB, Siegel GJ. 2004. Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease. Expert Rev Vaccines 3:717-725.
-
(2004)
Expert Rev Vaccines
, vol.3
, pp. 717-725
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
12
-
-
13444283725
-
Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8
-
Chauhan NB, Siegel GJ. 2005. Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8. Neurosci Lett 375:143-147.
-
(2005)
Neurosci Lett
, vol.375
, pp. 143-147
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
13
-
-
0035888264
-
Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain
-
Chauhan NB, Siegel GJ, Lichtor T. 2001. Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain. J Neurosci Res 66:231-235.
-
(2001)
J Neurosci Res
, vol.66
, pp. 231-235
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lichtor, T.3
-
14
-
-
9644305699
-
Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Abeta antibody into the third ventricle of TgCRND8 mice
-
Chauhan NB, Siegel GJ, Lichtor T. 2004a. Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Abeta antibody into the third ventricle of TgCRND8 mice. J Neurosci Res 78:732-741.
-
(2004)
J Neurosci Res
, vol.78
, pp. 732-741
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lichtor, T.3
-
15
-
-
4644308807
-
Effects of lovastatin and pravastatin on amyloid processing and cerebral inflammatory response in TgCRND8 brain
-
Chauhan NB, Siegel GJ, Feinstein DL. 2004b. Effects of lovastatin and pravastatin on amyloid processing and cerebral inflammatory response in TgCRND8 brain. Neurochem Res 29:1897-1911.
-
(2004)
Neurochem Res
, vol.29
, pp. 1897-1911
-
-
Chauhan, N.B.1
Siegel, G.J.2
Feinstein, D.L.3
-
16
-
-
0035877756
-
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
-
Chishti MA, Yang DS, Janus C, Phinney AL, Home P, Pearson J, Strome R, Zuker N, Loukides J, French J, Turner S, Lozza G, Grilli M, Kunicki S, Morissette C, Paquette J, Gervais F, Bergeron C, Fraser PE, Carlson GA, St. George-Hyslop P, Westaway D. 2001. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 276:21562-21570.
-
(2001)
J Biol Chem
, vol.276
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.S.2
Janus, C.3
Phinney, A.L.4
Home, P.5
Pearson, J.6
Strome, R.7
Zuker, N.8
Loukides, J.9
French, J.10
Turner, S.11
Lozza, G.12
Grilli, M.13
Kunicki, S.14
Morissette, C.15
Paquette, J.16
Gervais, F.17
Bergeron, C.18
Fraser, P.E.19
Carlson, G.A.20
St. George-Hyslop, P.21
Westaway, D.22
more..
-
17
-
-
5344272541
-
A focus on the synapse for neuroprotection in Alzheimer's disease and other dementias
-
Coleman P, Federoff H, Kurlan R. 2004. A focus on the synapse for neuroprotection in Alzheimer's disease and other dementias. Neurology 63:1155-1162.
-
(2004)
Neurology
, vol.63
, pp. 1155-1162
-
-
Coleman, P.1
Federoff, H.2
Kurlan, R.3
-
19
-
-
4644293577
-
Conformation-dependent antibodies target diseases of protein misfolding
-
Glabe CG. 2004. Conformation-dependent antibodies target diseases of protein misfolding. Trends Biochem Sci 29:542-547.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 542-547
-
-
Glabe, C.G.1
-
20
-
-
33644861975
-
Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis
-
Glabe CG, Kayed R. 2006. Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis. Neurology 66(Suppl 1):S74-S78.
-
(2006)
Neurology
, vol.66
, Issue.SUPPL. 1
-
-
Glabe, C.G.1
Kayed, R.2
-
21
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy JA, Higgins GA. 1992. Alzheimer's disease: the amyloid cascade hypothesis. Science 256:184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
22
-
-
0037135111
-
-
Hardy J, Selkoe DJ. 2002. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 297:353-356 [erratum in Science 297:2209, 2002].
-
Hardy J, Selkoe DJ. 2002. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 297:353-356 [erratum in Science 297:2209, 2002].
-
-
-
-
23
-
-
0033740610
-
Mechanisms of beta-amyloid neurotoxicity: Perspectives of pharmacotherapy
-
Harkany T, Abraham I, Konya C, Nyakas C, Zarandi M, Penke B, Luiten PG. 2000. Mechanisms of beta-amyloid neurotoxicity: perspectives of pharmacotherapy. Rev Neurosci 11:329-382.
-
(2000)
Rev Neurosci
, vol.11
, pp. 329-382
-
-
Harkany, T.1
Abraham, I.2
Konya, C.3
Nyakas, C.4
Zarandi, M.5
Penke, B.6
Luiten, P.G.7
-
24
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia AY, Masliah E, McConlogue L, Yu GQ, Tatsuno G, Hu K, Kholodenko D, Malenka RC, Nicoll RA, Mucke L. 1999. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci U S A 96:3228-3233.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
25
-
-
0034677660
-
Structural studies of soluble oligomers of the Alzheimer beta-amyloid peptide
-
Huang TH, Yang DS, Plaskos NP, Go S, Yip CM, Fraser PE, Chakrabartty A. 2000. Structural studies of soluble oligomers of the Alzheimer beta-amyloid peptide. J Mol Biol 297:73-87.
-
(2000)
J Mol Biol
, vol.297
, pp. 73-87
-
-
Huang, T.H.1
Yang, D.S.2
Plaskos, N.P.3
Go, S.4
Yip, C.M.5
Fraser, P.E.6
Chakrabartty, A.7
-
26
-
-
0034700471
-
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus C, Pearson J, McLaurin J, Mathews PM, Jiang Y, Schmidt SD, Chishti MA, Horne P, Heslin D, French J, Mount HT, Nixon RA, Mercken M, Bergeron C, Fraser PE, St. George-Hyslop P, Westaway D. 2000. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 408:979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
Mount, H.T.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
St. George-Hyslop, P.16
Westaway, D.17
-
27
-
-
0023905906
-
Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques
-
Katzman R, Terry R, DeTeresa R, Brown T, Davies P, Fuld P, Renbing X, Peck A. 1988. Clinical, pathological, and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques. Ann Neurol 23:138-144.
-
(1988)
Ann Neurol
, vol.23
, pp. 138-144
-
-
Katzman, R.1
Terry, R.2
DeTeresa, R.3
Brown, T.4
Davies, P.5
Fuld, P.6
Renbing, X.7
Peck, A.8
-
28
-
-
11144356498
-
Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease
-
Kawarabayashi T, Shoji M, Younkin LH, Wen-Lang L, Dickson DW, Murakami T, Matsubara E, Abe K, Ashe KH, Younkin SG. 2004. Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease. J Neurosci 24:3801-3809.
-
(2004)
J Neurosci
, vol.24
, pp. 3801-3809
-
-
Kawarabayashi, T.1
Shoji, M.2
Younkin, L.H.3
Wen-Lang, L.4
Dickson, D.W.5
Murakami, T.6
Matsubara, E.7
Abe, K.8
Ashe, K.H.9
Younkin, S.G.10
-
29
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. 2003. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300:486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
30
-
-
8744220663
-
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases
-
Kayed R, Sokolov Y, Edmonds B, Mclntire TM, Milton SC, Hall JE, Glabe CG. 2004. Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases. J Biol Chem 279:46363-46366.
-
(2004)
J Biol Chem
, vol.279
, pp. 46363-46366
-
-
Kayed, R.1
Sokolov, Y.2
Edmonds, B.3
Mclntire, T.M.4
Milton, S.C.5
Hall, J.E.6
Glabe, C.G.7
-
31
-
-
0035993237
-
Abeta toxicity in Alzheimer's disease: Globular oligomers (ADDLs) as new vaccine and drug targets
-
Klein WL. 2002. Abeta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets. Neurochem Int 41:345-352.
-
(2002)
Neurochem Int
, vol.41
, pp. 345-352
-
-
Klein, W.L.1
-
32
-
-
21044453723
-
Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo
-
Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, Spooner ET, Jiang L, Anwyl R, Selkoe DJ, Rowan MJ. 2005. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. Nat Med 11:556-561.
-
(2005)
Nat Med
, vol.11
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
Spooner, E.T.7
Jiang, L.8
Anwyl, R.9
Selkoe, D.J.10
Rowan, M.J.11
-
33
-
-
0029671451
-
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains
-
Kuo YM, Emmerling MR, Vigo-Pelfrey C, Kasunic TC, Kirkpatrick JB, Murdoch GH, Ball MJ, Roher AE. 1996. Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains. J Biol Chem 271:4077-4081.
-
(1996)
J Biol Chem
, vol.271
, pp. 4077-4081
-
-
Kuo, Y.M.1
Emmerling, M.R.2
Vigo-Pelfrey, C.3
Kasunic, T.C.4
Kirkpatrick, J.B.5
Murdoch, G.H.6
Ball, M.J.7
Roher, A.E.8
-
34
-
-
20844458090
-
Synaptic targeting by Alzheimer's-related amyloid beta oligomers
-
Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. 2004. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J Neurosci 24:10191-10200.
-
(2004)
J Neurosci
, vol.24
, pp. 10191-10200
-
-
Lacor, P.N.1
Buniel, M.C.2
Chang, L.3
Fernandez, S.J.4
Gong, Y.5
Viola, K.L.6
Lambert, M.P.7
Velasco, P.T.8
Bigio, E.H.9
Finch, C.E.10
Krafft, G.A.11
Klein, W.L.12
-
35
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M, Morgan TE, Rozovsky I, Trommer B, Viola KL, Wals P, Zhang C, Finch CE, Krafft GA, Klein WL. 1998. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci U S A 95:6448-6453.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
36
-
-
0035653328
-
Memory loss independent of plaque formation in Alzheimer's model
-
Love R. 2001. Memory loss independent of plaque formation in Alzheimer's model. Lancet 358:1879.
-
(2001)
Lancet
, vol.358
, pp. 1879
-
-
Love, R.1
-
37
-
-
0032888131
-
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
-
Lue LF, Kuo YM, Roher AE, Brachova L, Shen Y, Sue L, Beach T, Kurth JH, Rydel RE, Rogers J. 1999. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease. Am J Pathol 155:853-862.
-
(1999)
Am J Pathol
, vol.155
, pp. 853-862
-
-
Lue, L.F.1
Kuo, Y.M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
Beach, T.7
Kurth, J.H.8
Rydel, R.E.9
Rogers, J.10
-
38
-
-
31844439888
-
Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro
-
Ma QL, Lim GP, Harris-White ME, Yang F, Ambegaokar SS, Ubeda OJ, Glabe CG, Teter B, Frautschy SA, Cole GM. 2006. Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro. J Neurosci Res 83:374-384.
-
(2006)
J Neurosci Res
, vol.83
, pp. 374-384
-
-
Ma, Q.L.1
Lim, G.P.2
Harris-White, M.E.3
Yang, F.4
Ambegaokar, S.S.5
Ubeda, O.J.6
Glabe, C.G.7
Teter, B.8
Frautschy, S.A.9
Cole, G.M.10
-
39
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, Bush AI, Masters CL. 1999. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 46:860-866.
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
40
-
-
84984755327
-
-
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. 2000. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408:982-985 [erratum in Nature 412:660, 2001].
-
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. 2000. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408:982-985 [erratum in Nature 412:660, 2001].
-
-
-
-
41
-
-
0034213718
-
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
-
Mucke L, Masliah E, Yu GQ, Mallory M, Rockenstein EM, Tatsuno G, Hu K, Kholodenko D, Johnson-Wood K, McConlogue L. 2000. High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J Neurosci 20:4050-4058.
-
(2000)
J Neurosci
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
Hu, K.7
Kholodenko, D.8
Johnson-Wood, K.9
McConlogue, L.10
-
42
-
-
0038117796
-
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
-
Naslund J, Haroutunian V, Mohs R, Davis KL, Davies P, Greengard P, Buxbaum JD. 2000. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA 283:1571-1577.
-
(2000)
JAMA
, vol.283
, pp. 1571-1577
-
-
Naslund, J.1
Haroutunian, V.2
Mohs, R.3
Davis, K.L.4
Davies, P.5
Greengard, P.6
Buxbaum, J.D.7
-
43
-
-
27144530643
-
Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice
-
Palop JJ, Chin J, Bien-Ly N, Massaro C, Yeung BZ, Yu GQ, Mucke L. 2005. Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice. J Neurosci 25:9686-9693.
-
(2005)
J Neurosci
, vol.25
, pp. 9686-9693
-
-
Palop, J.J.1
Chin, J.2
Bien-Ly, N.3
Massaro, C.4
Yeung, B.Z.5
Yu, G.Q.6
Mucke, L.7
-
44
-
-
23144463734
-
Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies
-
Pereira C, Agostinho P, Moreira PI, Cardoso SM, Oliveira CR. 2005. Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies. Curr Drug Targets CNS Neurol Disord 4:383-403.
-
(2005)
Curr Drug Targets CNS Neurol Disord
, vol.4
, pp. 383-403
-
-
Pereira, C.1
Agostinho, P.2
Moreira, P.I.3
Cardoso, S.M.4
Oliveira, C.R.5
-
45
-
-
9444245809
-
Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease
-
Roher AE, Chaney MO, Kuo YM, Webster SD, Stine WB, Haverkamp LJ, Woods AS, Cotter RJ, Tuohy JM, Krafit GA, Bonnell BS, Emmerling MR. 1996. Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease. J Biol Chem 271:20631-20635.
-
(1996)
J Biol Chem
, vol.271
, pp. 20631-20635
-
-
Roher, A.E.1
Chaney, M.O.2
Kuo, Y.M.3
Webster, S.D.4
Stine, W.B.5
Haverkamp, L.J.6
Woods, A.S.7
Cotter, R.J.8
Tuohy, J.M.9
Krafit, G.A.10
Bonnell, B.S.11
Emmerling, M.R.12
-
46
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Liao Z, Lieberburg I, Motter R, Mutter L, Soriano F, Shopp G, Vasquez N, Vandevert C, Walker S, Wogulis M, Yednock T, Games D, Seubert P. 1999. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400:173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
47
-
-
13344293701
-
Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome
-
Teller JK, Russo C, DeBusk LM, Angelini G, Zaccheo D, Dagna-Bricarelli F, Scartezzini P, Bertolini S, Mann DM, Tabaton M, Gambetti P. 1996. Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome. Nat Med 2:93-95.
-
(1996)
Nat Med
, vol.2
, pp. 93-95
-
-
Teller, J.K.1
Russo, C.2
DeBusk, L.M.3
Angelini, G.4
Zaccheo, D.5
Dagna-Bricarelli, F.6
Scartezzini, P.7
Bertolini, S.8
Mann, D.M.9
Tabaton, M.10
Gambetti, P.11
-
48
-
-
0028218871
-
Neuropathological changes in Alzheimer disease
-
Terry RD. 1994. Neuropathological changes in Alzheimer disease. Prog Brain Res 101:383-390.
-
(1994)
Prog Brain Res
, vol.101
, pp. 383-390
-
-
Terry, R.D.1
-
49
-
-
0002080057
-
The neuropathology of Alzheimer's disease and the structural basis of its cognitive alterations
-
Terry RD, Katzman R, Bick KL, Sisodia SS, editors, Philadelphia: Lippincott Williams and Wilkins. p
-
Terry RD. 1999. The neuropathology of Alzheimer's disease and the structural basis of its cognitive alterations. In: Terry RD, Katzman R, Bick KL, Sisodia SS, editors. Alzheimer's disease. Philadelphia: Lippincott Williams and Wilkins. p 187-206.
-
(1999)
Alzheimer's disease
, pp. 187-206
-
-
Terry, R.D.1
-
50
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, Hansen LA, Katzman R. 1991. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30:572-580.
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
DeTeresa, R.5
Hill, R.6
Hansen, L.A.7
Katzman, R.8
-
51
-
-
0037266894
-
Age-dependent cognitive decline in the APP23 model precedes amyloid deposition
-
Van Dam D, D'Hooge R, Staufenbiel M, Van Ginneken C, Van Meir F, De Deyn PP. 2003. Age-dependent cognitive decline in the APP23 model precedes amyloid deposition. Eur J Neurosci 17:388-396.
-
(2003)
Eur J Neurosci
, vol.17
, pp. 388-396
-
-
Van Dam, D.1
D'Hooge, R.2
Staufenbiel, M.3
Van Ginneken, C.4
Van Meir, F.5
De Deyn, P.P.6
-
52
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
Walsh DM, Selkoe DJ. 2004. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 44:181-193.
-
(2004)
Neuron
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
53
-
-
0036669881
-
Amyloid-beta oligomers: Their production, toxicity and therapeutic inhibition
-
Walsh DM, Klyubin I, Fadeeva JV, Rowan MJ, Selkoe DJ. 2002a. Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition. Biochem Soc Trans 30:552-557.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 552-557
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Rowan, M.J.4
Selkoe, D.J.5
-
54
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ, Selkoe DJ. 2002b. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416:535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
55
-
-
29044443820
-
Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease
-
Watson D, Castano E, Kokjohn TA, Kuo YM, Lyubchenko Y, Pinsky D, Connolly ES Jr, Esh C, Luehrs DC, Stine WB, Rowse LM, Emmerling MR, Roher AE. 2005. Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease. Neurol Res 27:869-881.
-
(2005)
Neurol Res
, vol.27
, pp. 869-881
-
-
Watson, D.1
Castano, E.2
Kokjohn, T.A.3
Kuo, Y.M.4
Lyubchenko, Y.5
Pinsky, D.6
Connolly Jr, E.S.7
Esh, C.8
Luehrs, D.C.9
Stine, W.B.10
Rowse, L.M.11
Emmerling, M.R.12
Roher, A.E.13
-
56
-
-
0032521111
-
Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo
-
Weldon DT, Rogers SD, Ghilardi JR, Finke MP, Cleary JP, O'Hare E, Esler WP, Maggio JE, Mantyh PW. 1998. Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo. J Neurosci 18:2161-2173.
-
(1998)
J Neurosci
, vol.18
, pp. 2161-2173
-
-
Weldon, D.T.1
Rogers, S.D.2
Ghilardi, J.R.3
Finke, M.P.4
Cleary, J.P.5
O'Hare, E.6
Esler, W.P.7
Maggio, J.E.8
Mantyh, P.W.9
-
57
-
-
18944407388
-
Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death
-
Wogulis M, Wright S, Cunningham D, Chilcote T, Powell K, Rydel RE. 2005. Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death. J Neurosci 25:1071-1080.
-
(2005)
J Neurosci
, vol.25
, pp. 1071-1080
-
-
Wogulis, M.1
Wright, S.2
Cunningham, D.3
Chilcote, T.4
Powell, K.5
Rydel, R.E.6
|