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Volumn 78, Issue 5, 2004, Pages 732-741

Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Aβ antibody into the third ventricle of TgCRND8 mice

Author keywords

Alzheimer's disease; Anti A antibody; Cerebral amyloid angiopathy; Interleukin 1 ; Microglia; Passive immunization

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN ANTIBODY; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 9644305699     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20298     Document Type: Article
Times cited : (24)

References (31)
  • 1
    • 0035106780 scopus 로고    scopus 로고
    • Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
    • Bacskai BJ, Kajdasz ST, Christie RH, Carter C, Games D, Seubert P, Schenk D, Hyman BT. 2001. Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat Med 7:369-372.
    • (2001) Nat Med , vol.7 , pp. 369-372
    • Bacskai, B.J.1    Kajdasz, S.T.2    Christie, R.H.3    Carter, C.4    Games, D.5    Seubert, P.6    Schenk, D.7    Hyman, B.T.8
  • 3
    • 0036644989 scopus 로고    scopus 로고
    • Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody
    • Chauhan NB, Siegel GJ. 2002. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. J Neurosci Res 69:10-23.
    • (2002) J Neurosci Res , vol.69 , pp. 10-23
    • Chauhan, N.B.1    Siegel, G.J.2
  • 4
    • 0141758165 scopus 로고    scopus 로고
    • Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576
    • Chauhan NB, Siegel GJ. 2003. Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576. J Neurosci Res 74:142-147.
    • (2003) J Neurosci Res , vol.74 , pp. 142-147
    • Chauhan, N.B.1    Siegel, G.J.2
  • 5
    • 0035888264 scopus 로고    scopus 로고
    • Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain
    • Chauhan NB, Siegel GJ, Lichtor T. 2001. Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain. J Neurosci Res 66:231-235.
    • (2001) J Neurosci Res , vol.66 , pp. 231-235
    • Chauhan, N.B.1    Siegel, G.J.2    Lichtor, T.3
  • 7
    • 0034746897 scopus 로고    scopus 로고
    • Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition
    • Das P, Murphy MP, Younkin LH, Younkin SG, Golde TE. 2001. Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition. Neurobiol Aging 22:721-727.
    • (2001) Neurobiol Aging , vol.22 , pp. 721-727
    • Das, P.1    Murphy, M.P.2    Younkin, L.H.3    Younkin, S.G.4    Golde, T.E.5
  • 8
    • 0035902619 scopus 로고    scopus 로고
    • Peripheral anti-A beta antibody alters CNS and plasma A-beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
    • DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. 2001. Peripheral anti-A beta antibody alters CNS and plasma A-beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 98:8850-8855.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8850-8855
    • DeMattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Dodart, J.C.4    Paul, S.M.5    Holtzman, D.M.6
  • 10
    • 0037424110 scopus 로고    scopus 로고
    • Reduction of beta-amyloid plaques in brain of transgenic mouse model of Alzheimer's disease by EFRH-phage immunization
    • Frenkel D, Dewachter I, Van Leuven F, Solomon B. 2003. Reduction of beta-amyloid plaques in brain of transgenic mouse model of Alzheimer's disease by EFRH-phage immunization. Vaccine 21:1060-1065.
    • (2003) Vaccine , vol.21 , pp. 1060-1065
    • Frenkel, D.1    Dewachter, I.2    Van Leuven, F.3    Solomon, B.4
  • 15
    • 0034183020 scopus 로고    scopus 로고
    • Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease
    • Kuo YM, Crawford F, Mullan M, Kokjohn TA, Emmerling MR, Weller RO, Roher AE. 2000. Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease. Mol Med 6:430-439.
    • (2000) Mol Med , vol.6 , pp. 430-439
    • Kuo, Y.M.1    Crawford, F.2    Mullan, M.3    Kokjohn, T.A.4    Emmerling, M.R.5    Weller, R.O.6    Roher, A.E.7
  • 17
    • 0037031861 scopus 로고    scopus 로고
    • Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation
    • Mohajeri MH, Saini K, Schultz JG, Wollmer MA, Hock C, Nitsch RM. 2002. Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation. J Biol Chem 277:33012-33017.
    • (2002) J Biol Chem , vol.277 , pp. 33012-33017
    • Mohajeri, M.H.1    Saini, K.2    Schultz, J.G.3    Wollmer, M.A.4    Hock, C.5    Nitsch, R.M.6
  • 19
    • 84984755327 scopus 로고    scopus 로고
    • published erratum appears
    • Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. 2000. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408:982-985 [published erratum appears in Nature 412:660].
    • Nature , vol.412 , pp. 660
  • 20
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
    • Nicoll JA, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO. 2003. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med 9:448-452.
    • (2003) Nat Med , vol.9 , pp. 448-452
    • Nicoll, J.A.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 22
    • 0036780877 scopus 로고    scopus 로고
    • Amyloid-beta immunotherapy for Alzheimer's disease: The end of the beginning
    • Schenk D. 2002. Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning. Nat Rev Neurosci 3:824-828.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 824-828
    • Schenk, D.1
  • 24
    • 0028267440 scopus 로고
    • Normal and abnormal biology of the beta-amyloid precursor protein
    • Selkoe DJ. 1994. Normal and abnormal biology of the beta-amyloid precursor protein. Annu Rev Neurosci 17:489-517.
    • (1994) Annu Rev Neurosci , vol.17 , pp. 489-517
    • Selkoe, D.J.1
  • 25
    • 0034884382 scopus 로고    scopus 로고
    • Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
    • Sigurdsson EM, Scholtzova H, Mehta PD, Frangione B, Wisniewski T. 2001. Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am J Pathol 159:439-447.
    • (2001) Am J Pathol , vol.159 , pp. 439-447
    • Sigurdsson, E.M.1    Scholtzova, H.2    Mehta, P.D.3    Frangione, B.4    Wisniewski, T.5
  • 27
    • 0035695315 scopus 로고    scopus 로고
    • Imnumotherapeutic strategies for prevention and treatment of Alzheimer's disease
    • Solomon B. 2001. Imnumotherapeutic strategies for prevention and treatment of Alzheimer's disease. DNA Cell Biol 20:697-703.
    • (2001) DNA Cell Biol , vol.20 , pp. 697-703
    • Solomon, B.1
  • 28
    • 0036914592 scopus 로고    scopus 로고
    • Immunological approaches as therapy for Alzheimer's disease
    • Solomon B. 2002. Immunological approaches as therapy for Alzheimer's disease. Expert Opin Biol Ther 2:907-917.
    • (2002) Expert Opin Biol Ther , vol.2 , pp. 907-917
    • Solomon, B.1
  • 29
    • 0037180823 scopus 로고    scopus 로고
    • Inflammation and therapeutic vaccination in CNS diseases
    • Weiner HL, Selkoe DJ. 2002. Inflammation and therapeutic vaccination in CNS diseases. Nature 420:879-884.
    • (2002) Nature , vol.420 , pp. 879-884
    • Weiner, H.L.1    Selkoe, D.J.2
  • 31
    • 0037531198 scopus 로고    scopus 로고
    • Intracranially administered anti-Abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation
    • Wilcock DM, DiCarlo G, Henderson D, Jackson J, Clarke K, Ugen KE, Gordon MN, Morgan D. 2003. Intracranially administered anti-Abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation. J Neurosci 23:3745-3751.
    • (2003) J Neurosci , vol.23 , pp. 3745-3751
    • Wilcock, D.M.1    DiCarlo, G.2    Henderson, D.3    Jackson, J.4    Clarke, K.5    Ugen, K.E.6    Gordon, M.N.7    Morgan, D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.