-
1
-
-
0037436022
-
Cerebral hemorrhage and amyloid-beta
-
Atwood CS, Perry G, Smith MA. 2003. Cerebral hemorrhage and amyloid-beta. Science 299:1014.
-
(2003)
Science
, vol.299
, pp. 1014
-
-
Atwood, C.S.1
Perry, G.2
Smith, M.A.3
-
2
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer's disease
-
Bard F, Cannon C, Barbour R, Burke RL, Games D, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Lieberburg I, Motter R, Nguyen M, Soriano F, Vasquez N, Weiss K, Welch B, Seubert P, Schenk D, Yednock T. 2000. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer's disease. Nat Med 6:916-919.
-
(2000)
Nat Med
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, M.13
Lieberburg, I.14
Motter, R.15
Nguyen, M.16
Soriano, F.17
Vasquez, N.18
Weiss, K.19
Welch, B.20
Seubert, P.21
Schenk, D.22
Yednock, T.23
more..
-
3
-
-
0036644989
-
Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody
-
Chauhan NB, Siegel GJ. 2002. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. J Neurosci Res 69:10-23.
-
(2002)
J Neurosci Res
, vol.69
, pp. 10-23
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
4
-
-
0035888264
-
Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain
-
Chauhan NB, Siegel GJ, Lichtor T. 2001. Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain. J Neurosci Res 66:231-235.
-
(2001)
J Neurosci Res
, vol.66
, pp. 231-235
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lichtor, T.3
-
5
-
-
0034746897
-
Reduced effectiveness of Aβ1-42 immunization in APP transgenic mice with significant amyloid deposition
-
Das P, Paul M, Murphy LH, Younkin S, Younkin G, Golde TE. 2001. Reduced effectiveness of Aβ1-42 immunization in APP transgenic mice with significant amyloid deposition. Neurobiol Aging 22:721-727.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 721-727
-
-
Das, P.1
Paul, M.2
Murphy, L.H.3
Younkin, S.4
Younkin, G.5
Golde, T.E.6
-
6
-
-
0035902619
-
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
-
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. 2001. Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 98:8850-8855.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8850-8855
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.C.4
Paul, S.M.5
Holtzman, D.M.6
-
7
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
-
Dodart JC, Bales KR, Gannon KS, Greene SJ, DeMattos RB, Mathis C, DeLong CA, Wu S, Wu X, Holtzman DM, Paul SM. 2002. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nat Neurosci 5:452-457.
-
(2002)
Nat Neurosci
, vol.5
, pp. 452-457
-
-
Dodart, J.C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
DeMattos, R.B.5
Mathis, C.6
DeLong, C.A.7
Wu, S.8
Wu, X.9
Holtzman, D.M.10
Paul, S.M.11
-
8
-
-
0034633632
-
Immunization against Alzheimer's β-amyloid plaques via EFRH phage administration
-
Frenkel D, Katz O, Solomon B. 2000. Immunization against Alzheimer's β-amyloid plaques via EFRH phage administration. Proc Natl Acad Sci USA 97:11455-11459.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11455-11459
-
-
Frenkel, D.1
Katz, O.2
Solomon, B.3
-
9
-
-
0037317234
-
Vaccination with amyloid-beta peptide induces autoimmune encephalomyelitis in C57/BL6 mice
-
Furlan R, Brambilla E, Sanvito F, Roccatagliata L, Olivieri S, Bergami A, Pluchino S, Uccelli A, Comi G, Martino G. 2003. Vaccination with amyloid-beta peptide induces autoimmune encephalomyelitis in C57/BL6 mice. Brain 126(Pt 2):285-291.
-
(2003)
Brain
, vol.126
, Issue.PART 2
, pp. 285-291
-
-
Furlan, R.1
Brambilla, E.2
Sanvito, F.3
Roccatagliata, L.4
Olivieri, S.5
Bergami, A.6
Pluchino, S.7
Uccelli, A.8
Comi, G.9
Martino, G.10
-
10
-
-
0026735070
-
Targeting of cell-surface beta-amyloid precursor protein to lysosomes: Alternative processing into amyloid-bearing fragments
-
Haass C, Koo EH, Mellon A, Hung AY, Selkoe DJ. 1992. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments. Nature 357:500-503.
-
(1992)
Nature
, vol.357
, pp. 500-503
-
-
Haass, C.1
Koo, E.H.2
Mellon, A.3
Hung, A.Y.4
Selkoe, D.J.5
-
11
-
-
0034700471
-
A beta peptide immunization reduces behavioral impairment and plaques in a model of Alzheimer's disease
-
Janus C, Pearson J, McLaurin J, Mathews PM, Jiang Y, Schmidt SD, Chishti MA, Home P, Heslin D, French J, Mount HT, Nixon, RA, Mercken M, Bergeron C, Fraser PE, St. George-Hyslop P, Westaway D. 2000. A beta peptide immunization reduces behavioral impairment and plaques in a model of Alzheimer's disease. Nature 408:979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Home, P.8
Heslin, D.9
French, J.10
Mount, H.T.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
St. George-Hyslop, P.16
Westaway, D.17
-
12
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Muller-Hill B. 1987. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325:733-736.
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
13
-
-
0001804233
-
Neuroanatomical and neuropathological changes during aging and dementia
-
Albert ML, Knoefel JE, editors. New York: Oxford University Press
-
Kemper TL. 1994. Neuroanatomical and neuropathological changes during aging and dementia. In: Albert ML, Knoefel JE, editors. Clinical neurology of aging, 2nd ed. New York: Oxford University Press. p 3-67.
-
(1994)
Clinical Neurology of Aging, 2nd Ed.
, pp. 3-67
-
-
Kemper, T.L.1
-
14
-
-
0034183020
-
Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease
-
Kuo YM, Crawford F, Mullan M, Kokjohn TA, Emmerling MR, Weller RO, Roher AE. 2000. Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease. Mol Med 6:430-439.
-
(2000)
Mol Med
, vol.6
, pp. 430-439
-
-
Kuo, Y.M.1
Crawford, F.2
Mullan, M.3
Kokjohn, T.A.4
Emmerling, M.R.5
Weller, R.O.6
Roher, A.E.7
-
15
-
-
0026743208
-
Amyloid precursor protein is localized in growing neurites of neonatal rat brain
-
Masliah E, Mallory M, Ge N, Saitoh T. 1992. Amyloid precursor protein is localized in growing neurites of neonatal rat brain. Brain Res 593:323-328.
-
(1992)
Brain Res
, vol.593
, pp. 323-328
-
-
Masliah, E.1
Mallory, M.2
Ge, N.3
Saitoh, T.4
-
16
-
-
0037405981
-
Is there a future for vaccination as a treatment for Alzheimer's disease?
-
McGeer PL, McGeer E. 2003. Is there a future for vaccination as a treatment for Alzheimer's disease? Neurobiol Aging 24:391-395.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 391-395
-
-
McGeer, P.L.1
McGeer, E.2
-
17
-
-
0032960305
-
Regulation of amyloid precursor protein cleavage
-
Mills J, Reiner PB. 1999. Regulation of amyloid precursor protein cleavage. J Neurochem 72:443-460.
-
(1999)
J Neurochem
, vol.72
, pp. 443-460
-
-
Mills, J.1
Reiner, P.B.2
-
18
-
-
0037031861
-
Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation
-
Mohajeri MH, Saini K, Schultz JG, Wollmer MA, Hock C, Nitsch RM. 2002. Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation. J Biol Chem 277:33012-33017.
-
(2002)
J Biol Chem
, vol.277
, pp. 33012-33017
-
-
Mohajeri, M.H.1
Saini, K.2
Schultz, J.G.3
Wollmer, M.A.4
Hock, C.5
Nitsch, R.M.6
-
19
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. 2000. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408:982-985.
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
Duff, K.7
Jantzen, P.8
DiCarlo, G.9
Wilcock, D.10
Connor, K.11
Hatcher, J.12
Hope, C.13
Gordon, M.14
Arendash, G.W.15
-
20
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
-
epub ahead of print
-
Nicoll JA, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO. 2003. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med [epub ahead of print].
-
(2003)
Nat Med
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
21
-
-
0037112201
-
Cerebral hemorrhage after passive anti-Abeta immunotherapy
-
Pfeifer M, Boncristiano S, Bondolfi L, Stalder A, Deller T, Staufenbiel M, Mathews PM, Jucker M. 2002. Cerebral hemorrhage after passive anti-Abeta immunotherapy. Science 298:1379.
-
(2002)
Science
, vol.298
, pp. 1379
-
-
Pfeifer, M.1
Boncristiano, S.2
Bondolfi, L.3
Stalder, A.4
Deller, T.5
Staufenbiel, M.6
Mathews, P.M.7
Jucker, M.8
-
22
-
-
0034767469
-
Management of hydrocephalus in pediatric patients with posterior fossa tumors: The role of endoscopic third ventriculostomy
-
Sainte-Rose C, Cinalli G, Roux FE, Maixner R, Chumas PD, Mansour M, Carpentier A, Bourgeois M, Zerah M, Pierre-Kahn A, Renier D. 2001. Management of hydrocephalus in pediatric patients with posterior fossa tumors: the role of endoscopic third ventriculostomy. J Neurosurg 95:791-797.
-
(2001)
J Neurosurg
, vol.95
, pp. 791-797
-
-
Sainte-Rose, C.1
Cinalli, G.2
Roux, F.E.3
Maixner, R.4
Chumas, P.D.5
Mansour, M.6
Carpentier, A.7
Bourgeois, M.8
Zerah, M.9
Pierre-Kahn, A.10
Renier, D.11
-
23
-
-
0036780877
-
Amyloid-beta immunotherapy for Alzheimer's disease: The end of the beginning
-
Schenk D. 2002. Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning. Nat Rev Neurosci 3:824-828.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 824-828
-
-
Schenk, D.1
-
24
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee, M, Liao Z, Lieberburg I, Motter R, Mutter L, Soriano F, Shopp G, Vasquez N, Vandevert C, Walker S, Wogulis M, Yednock T, Games D, Seubert P. 1999. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400:173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
25
-
-
0028267440
-
Normal and abnormal biology of the beta-amyloid precursor protein
-
Selkoe DJ. 1994. Normal and abnormal biology of the beta-amyloid precursor protein. Annu Rev Neurosci 17:489-517.
-
(1994)
Annu Rev Neurosci
, vol.17
, pp. 489-517
-
-
Selkoe, D.J.1
-
26
-
-
0029784838
-
Amyloid beta-protein and the genetics of Alzheimer's disease
-
Selkoe DJ. 1996. Amyloid beta-protein and the genetics of Alzheimer's disease. J Biol Chem 271:18295-18298.
-
(1996)
J Biol Chem
, vol.271
, pp. 18295-18298
-
-
Selkoe, D.J.1
-
27
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
-
Seubert P, Vigo-Pelfrey C, Esch F, Lee M, Dovey H, Davis D, Sinha S, Schlossmacher M, Whaley J, Swindlehurst C, McCormak R, Wolfert R, Selkoe D, Lieberberg I, Schenk D. 1992. Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature 359:325-327.
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
Sinha, S.7
Schlossmacher, M.8
Whaley, J.9
Swindlehurst, C.10
McCormak, R.11
Wolfert, R.12
Selkoe, D.13
Lieberberg, I.14
Schenk, D.15
-
28
-
-
0034884382
-
Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
-
Sigurdsson EM, Scholtzova H, Mehta PD, Frangione B, Wisniewski T. 2001. Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am J Pathol 159:439-447.
-
(2001)
Am J Pathol
, vol.159
, pp. 439-447
-
-
Sigurdsson, E.M.1
Scholtzova, H.2
Mehta, P.D.3
Frangione, B.4
Wisniewski, T.5
-
30
-
-
0035949755
-
Cholesterol and Alzheimer's disease: Is there a link?
-
Simons M, Keller P, Dichgans J, Schulz JB. 2001. Cholesterol and Alzheimer's disease: is there a link? Neurology 57:1089-1093.
-
(2001)
Neurology
, vol.57
, pp. 1089-1093
-
-
Simons, M.1
Keller, P.2
Dichgans, J.3
Schulz, J.B.4
-
31
-
-
0036713813
-
Endoscopic third ventriculostomy in patients with cerebrospinal fluid infection and/or hemorrhage
-
Siomin V, Cinalli G, Grotenhuis A, Golash A, Oi S, Kothbauer K, Weiner H, Roth J, Beni-Adani L, Pierre-Kahn A, Takahashi Y, Mallucci C, Abbott R, Wisoff J, Constantini S. 2002. Endoscopic third ventriculostomy in patients with cerebrospinal fluid infection and/or hemorrhage. J Neurosurg 97:519-524.
-
(2002)
J Neurosurg
, vol.97
, pp. 519-524
-
-
Siomin, V.1
Cinalli, G.2
Grotenhuis, A.3
Golash, A.4
Oi, S.5
Kothbauer, K.6
Weiner, H.7
Roth, J.8
Beni-Adani, L.9
Pierre-Kahn, A.10
Takahashi, Y.11
Mallucci, C.12
Abbott, R.13
Wisoff, J.14
Constantini, S.15
-
33
-
-
0035695315
-
Immunotherapeutic strategies for prevention and treatment of Alzheimer's disease
-
Solomon B. 2001. Immunotherapeutic strategies for prevention and treatment of Alzheimer's disease. DNA Cell Biol 20:697-703.
-
(2001)
DNA Cell Biol
, vol.20
, pp. 697-703
-
-
Solomon, B.1
-
34
-
-
0036484536
-
Towards Alzheimer's disease vaccination
-
Solomon B. 2002. Towards Alzheimer's disease vaccination. Mini Rev. Med Chem 2:85-92.
-
(2002)
Mini Rev Med Chem
, vol.2
, pp. 85-92
-
-
Solomon, B.1
-
35
-
-
0030058382
-
Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide
-
Solomon B, Koppel R, Hanan E, Katzav T. 1996. Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide. Proc Natl Acad Sci USA 93:452-455.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 452-455
-
-
Solomon, B.1
Koppel, R.2
Hanan, E.3
Katzav, T.4
-
37
-
-
0037180823
-
Inflammation and therapeutic vaccination in CNS diseases
-
Weiner HL, Selkoe DJ. 2002. Inflammation and therapeutic vaccination in CNS diseases. Nature 420:879-884.
-
(2002)
Nature
, vol.420
, pp. 879-884
-
-
Weiner, H.L.1
Selkoe, D.J.2
-
38
-
-
0033801852
-
Nasal administration of amyloid-b peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease
-
Weiner HL, Lemere CA, Maron R, Spooner ET, Grenfell TJ, Mori C, Issazadeh S, Hancock WW, Selkoe DJ. 2000. Nasal administration of amyloid-b peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease. Ann Neurol 48:567-579.
-
(2000)
Ann Neurol
, vol.48
, pp. 567-579
-
-
Weiner, H.L.1
Lemere, C.A.2
Maron, R.3
Spooner, E.T.4
Grenfell, T.J.5
Mori, C.6
Issazadeh, S.7
Hancock, W.W.8
Selkoe, D.J.9
-
39
-
-
0037531198
-
Intracranially administered anti-abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation
-
Wilcock DM, DiCarlo G, Henderson D, Jackson J, Clarke K, Ugen KE, Gordon MN, Morgan D. 2003. Intracranially administered anti-abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation. J Neurosci 23:3745-3751.
-
(2003)
J Neurosci
, vol.23
, pp. 3745-3751
-
-
Wilcock, D.M.1
DiCarlo, G.2
Henderson, D.3
Jackson, J.4
Clarke, K.5
Ugen, K.E.6
Gordon, M.N.7
Morgan, D.8
|