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Volumn 8, Issue 5, 2011, Pages 1446-1457

Genetic modification of stem cells for improved therapy of the infarcted myocardium

Author keywords

angiomyogenesis; gene therapy; heart; stem cells

Indexed keywords

CELL DIFFERENTIATION; CELL SURVIVAL; DNA MODIFICATION; EMBRYONIC STEM CELL; GENE DELIVERY SYSTEM; GENE EXPRESSION; HEART INFARCTION; HUMAN; NONHUMAN; PARACRINE SIGNALING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; SKELETAL MUSCLE; STEM CELL TRANSPLANTATION; TISSUE REGENERATION; TRANSGENICS;

EID: 80053475375     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp2001318     Document Type: Review
Times cited : (19)

References (142)
  • 1
    • 29244446484 scopus 로고    scopus 로고
    • AHA, Update
    • AHA (2009) Heart Disease and Stroke Statistics, 2009 Update. http://www.americanheart.org/downloadable/heart/ 123783441267009Heart%20and%20Stroke%20Update.pdf.
    • (2009) Heart Disease and Stroke Statistics, 2009
  • 3
    • 79955512050 scopus 로고    scopus 로고
    • Stem and progenitor cell-based therapy in ischaemic heart disease: Promise, uncertainties, and challenges
    • in press
    • Tongers, J.; Losordo, D. W.; Landmesser, U. Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges. Eur. Heart J. 2011, in press.
    • (2011) Eur. Heart J.
    • Tongers, J.1    Losordo, D.W.2    Landmesser, U.3
  • 6
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi, K.; Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 2006, 126, 663-676 (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 7
    • 77954605785 scopus 로고    scopus 로고
    • Recent stem cell advances: Induced pluripotent stem cells for disease modeling and stem cell-based regeneration
    • Yoshida, Y.; Yamanaka, S. Recent stem cell advances: induced pluripotent stem cells for disease modeling and stem cell-based regeneration Circulation 2010, 122, 80-87
    • (2010) Circulation , vol.122 , pp. 80-87
    • Yoshida, Y.1    Yamanaka, S.2
  • 8
    • 34548218373 scopus 로고    scopus 로고
    • MicroRNA with a macrofunction
    • Rane, S.; Sayed, D.; Abdellatif, M. MicroRNA with a MacroFunction Cell Cycle 2007, 6, 1850-1855 (Pubitemid 47327902)
    • (2007) Cell Cycle , vol.6 , Issue.15 , pp. 1850-1855
    • Rane, S.1    Sayed, D.2    Abdellatif, M.3
  • 9
    • 77955049511 scopus 로고    scopus 로고
    • Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells
    • Mallanna, S. K.; Rizzino, A. Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells Dev. Biol. 2010, 344, 16-25
    • (2010) Dev. Biol. , vol.344 , pp. 16-25
    • Mallanna, S.K.1    Rizzino, A.2
  • 12
    • 78651307763 scopus 로고    scopus 로고
    • Review article: Current status of myocardial regeneration: New cell sources and new strategies
    • Rangappa, S.; Makkar, R.; Forrester, J. Review article: current status of myocardial regeneration: new cell sources and new strategies J. Cardiovasc. Pharmacol Ther. 2011, 15, 338-343
    • (2011) J. Cardiovasc. Pharmacol Ther. , vol.15 , pp. 338-343
    • Rangappa, S.1    Makkar, R.2    Forrester, J.3
  • 18
    • 33646252939 scopus 로고    scopus 로고
    • Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement
    • DOI 10.1096/fj.05-5211com
    • Gnecchi, M.; He, H.; Noiseux, N.; Liang, O. D.; Zhang, L.; Morello, F.; Mu, H.; Melo, L. G.; Pratt, R. E.; Ingwall, J. S.; Dzau, V. J. Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement FASEB J. 2006, 20, 661-669 (Pubitemid 44933310)
    • (2006) FASEB Journal , vol.20 , Issue.6 , pp. 661-669
    • Gnecchi, M.1    He, H.2    Noiseux, N.3    Liang, O.D.4    Zhang, L.5    Morello, F.6    Mu, H.7    Melo, L.G.8    Pratt, R.E.9    Ingwall, J.S.10    Dzau, V.J.11
  • 19
    • 49049115952 scopus 로고    scopus 로고
    • Paracrine effects of cell transplantation: Modifying ventricular remodeling in the failing heart
    • Fedak, P. W. Paracrine effects of cell transplantation: modifying ventricular remodeling in the failing heart Semin. Thorac. Cardiovasc. Surg. 2008, 20, 87-93
    • (2008) Semin. Thorac. Cardiovasc. Surg. , vol.20 , pp. 87-93
    • Fedak, P.W.1
  • 22
    • 4644367092 scopus 로고    scopus 로고
    • Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: Phase i clinical study with 12 months of follow-up
    • DOI 10.1016/j.ahj.2004.03.043, PII S0002870304002017
    • Siminiak, T.; Kalawski, R.; Fiszer, D.; Jerzykowska, O.; Rzezniczak, J.; Rozwadowska, N.; Kurpisz, M. Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: phase I clinical study with 12 months of follow-up Am. Heart J. 2004, 148, 531-537 (Pubitemid 39265130)
    • (2004) American Heart Journal , vol.148 , Issue.3 , pp. 531-537
    • Siminiak, T.1    Kalawski, R.2    Fiszer, D.3    Jerzykowska, O.4    Rzezniczak, J.5    Rozwadowska, N.6    Kurpisz, M.7
  • 26
    • 25444444531 scopus 로고    scopus 로고
    • Repair of ischemic heart disease with novel bone marrow-derived multipotent stem cells
    • Lee, N.; Thorne, T.; Losordo, D. W.; Yoon, Y. S. Repair of ischemic heart disease with novel bone marrow-derived multipotent stem cells Cell Cycle 2005, 4, 861-864 (Pubitemid 41359745)
    • (2005) Cell Cycle , vol.4 , Issue.7 , pp. 861-864
    • Lee, N.1    Thorne, T.2    Losordo, D.W.3    Yoon, Y.-S.4
  • 27
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain: Expression of neuronal phenotypes in adult mice
    • DOI 10.1126/science.290.5497.1775
    • Brazelton, T. R.; Rossi, F. M.; Keshet, G. I.; Blau, H. M. From marrow to brain: expression of neuronal phenotypes in adult mice Science 2000, 290, 1775-1779 (Pubitemid 32004810)
    • (2000) Science , vol.290 , Issue.5497 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.V.2    Keshet, G.I.3    Blau, H.M.4
  • 29
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • DOI 10.1073/pnas.96.19.10711
    • Kopen, G. C.; Prockop, D. J.; Phinney, D. G. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 10711-10716 (Pubitemid 29442209)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.19 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 33
    • 0033958372 scopus 로고    scopus 로고
    • Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation
    • Theise, N. D.; Badve, S.; Saxena, R.; Henegariu, O.; Sell, S.; Crawford, J. M.; Krause, D. S. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation Hepatology 2009, 31, 235-240
    • (2009) Hepatology , vol.31 , pp. 235-240
    • Theise, N.D.1    Badve, S.2    Saxena, R.3    Henegariu, O.4    Sell, S.5    Crawford, J.M.6    Krause, D.S.7
  • 34
    • 0035805055 scopus 로고    scopus 로고
    • Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell
    • DOI 10.1016/S0092-8674(01)00328-2
    • Krause, D. S.; Theise, N. D.; Collector, M. I.; Henegariu, O.; Hwang, S.; Gardner, R.; Neutzel, S.; Sharkis, S. J. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell Cell 2001, 105, 369-377 (Pubitemid 32455343)
    • (2001) Cell , vol.105 , Issue.3 , pp. 369-377
    • Krause, D.S.1    Theise, N.D.2    Collector, M.I.3    Henegariu, O.4    Hwang, S.5    Gardner, R.6    Neutzel, S.7    Sharkis, S.J.8
  • 37
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • DOI 10.1161/hc0102.101442
    • Toma, C.; Pittenger, M. F.; Cahill, K. S.; Byrne, B. J.; Kessler, P. D. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart Circulation 2002, 105, 93-98 (Pubitemid 34049148)
    • (2002) Circulation , vol.105 , Issue.1 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3    Byrne, B.J.4    Kessler, P.D.5
  • 43
    • 77949350922 scopus 로고    scopus 로고
    • Long-term effects of intracoronary bone marrow cell transfer on diastolic function in patients after acute myocardial infarction: 5-year results from the randomized-controlled BOOST trial - An echocardiographic study
    • Schaefer, A.; Zwadlo, C.; Fuchs, M.; Meyer, G. P.; Lippolt, P.; Wollert, K. C.; Drexler, H. Long-term effects of intracoronary bone marrow cell transfer on diastolic function in patients after acute myocardial infarction: 5-year results from the randomized-controlled BOOST trial - an echocardiographic study Eur. J. Echocardiogr. 2010, 11, 165-171
    • (2010) Eur. J. Echocardiogr. , vol.11 , pp. 165-171
    • Schaefer, A.1    Zwadlo, C.2    Fuchs, M.3    Meyer, G.P.4    Lippolt, P.5    Wollert, K.C.6    Drexler, H.7
  • 44
    • 19344377947 scopus 로고    scopus 로고
    • Bone marrow stem cell transplantation for cardiac repair
    • Haider, H.; Ashraf, M. Bone marrow stem cell transplantation for cardiac repair Am. J. Physiol. 2005, 288, H2557-H2567
    • (2005) Am. J. Physiol. , vol.288
    • Haider, H.1    Ashraf, M.2
  • 46
    • 1942517003 scopus 로고    scopus 로고
    • R. C. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
    • Balsam
    • Balsam Wagers, L. B.; Christensen, A. J.; Kofidis, J. L.; Weissman, T.; Robbins, I. L. R. C. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium Nature 2004, 428, 668-673
    • (2004) Nature , vol.428 , pp. 668-673
    • Wagers, L.B.1    Christensen, A.J.2    Kofidis, J.L.3    Weissman, T.4    Robbins, I.L.5
  • 47
    • 4444274996 scopus 로고    scopus 로고
    • Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarction
    • Yoon, Y. S.; Park, J. S.; Tkebuchava, T.; Luedeman, C.; Losordo, D. W. Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarction Circulation 2004, 109, 3154-3157
    • (2004) Circulation , vol.109 , pp. 3154-3157
    • Yoon, Y.S.1    Park, J.S.2    Tkebuchava, T.3    Luedeman, C.4    Losordo, D.W.5
  • 48
    • 0035497343 scopus 로고    scopus 로고
    • The coronary delivery of marrow stromal cells for myocardial regeneration: Pathophysiologic and therapeutic implications
    • Wang, J. S.; Shum-Tim, D.; Chedrawy, E.; Chiu, R. C. The coronary delivery of marrow stromal cells for myocardial regeneration: pathophysiologic and therapeutic implications J. Thorac. Cardiovasc. Surg. 2001, 122, 699-705
    • (2001) J. Thorac. Cardiovasc. Surg. , vol.122 , pp. 699-705
    • Wang, J.S.1    Shum-Tim, D.2    Chedrawy, E.3    Chiu, R.C.4
  • 50
    • 40949164677 scopus 로고    scopus 로고
    • Cardioinductive network guiding stem cell differentiation revealed by proteomic cartography of tumor necrosis factor α-primed endodermal secretome
    • DOI 10.1634/stemcells.2007-0599
    • Arrell, D. K.; Niederlander, N. J.; Faustino, R. S.; Behfar, A.; Terzic, A. Cardioinductive network guiding stem cell differentiation revealed by proteomic cartography of tumor necrosis factor alpha-primed endodermal secretome Stem Cells 2008, 26, 387-400 (Pubitemid 351413599)
    • (2008) Stem Cells , vol.26 , Issue.2 , pp. 387-400
    • Arrell, D.K.1    Niederlander, N.J.2    Faustino, R.S.3    Behfar, A.4    Terzic, A.5
  • 51
    • 39849105758 scopus 로고    scopus 로고
    • Ventricular arrhythmias following intracoronary bone marrow stem cell transplantation
    • DOI 10.1093/europace/eum190
    • Villa, A.; Sanchez, P. L.; Fernandez-Aviles, F. Ventricular arrhythmias following intracoronary bone marrow stem cell transplantation Europace 2007, 9, 1222-1223 (Pubitemid 351773251)
    • (2007) Europace , vol.9 , Issue.12 , pp. 1222-1223
    • Villa, A.1    Sanchez, P.L.2    Fernandez-Aviles, F.3
  • 57
    • 0036487243 scopus 로고    scopus 로고
    • Skeletal muscle stem cells do not transdifferentiate into cardiomyocytes after cardiac grafting
    • DOI 10.1006/jmcc.2001.1507
    • Reinecke, H.; Poppa, V.; Murry, C. E. Skeletal muscle stem cells do not transdifferentiate into cardiomyocytes after cardiac grafting J. Mol. Cell. Cardiol. 2002, 34, 241-249 (Pubitemid 35222833)
    • (2002) Journal of Molecular and Cellular Cardiology , vol.34 , Issue.2 , pp. 241-249
    • Reinecke, H.1    Poppa, V.2    Murry, C.E.3
  • 62
    • 0038458986 scopus 로고    scopus 로고
    • New directions in strategies using cell therapy for heart disease
    • Itescu, S.; Schuster, M. D.; Kocher, A. A. New directions in strategies using cell therapy for heart disease J. Mol. Med. 2003, 81, 288-296 (Pubitemid 36718325)
    • (2003) Journal of Molecular Medicine , vol.81 , Issue.5 , pp. 288-296
    • Itescu, S.1    Schuster, M.D.2    Kocher, A.A.3
  • 63
    • 0842324789 scopus 로고    scopus 로고
    • Effectiveness of transient immunosuppression using cyclosporine for xenomyoblast transplantation for cardiac repair
    • DOI 10.1016/j.transproceed.2003.11.001
    • Haider, H.; Jiang, S. J.; Ye, L.; Aziz, S.; Law, P. K.; Sim, E. K. Effectiveness of transient immunosuppression using cyclosporine for xenomyoblast transplantation for cardiac repair Transplant Proc. 2004, 36, 232-235 (Pubitemid 38177241)
    • (2004) Transplantation Proceedings , vol.36 , Issue.1 , pp. 232-235
    • Haider, H.Kh.1    Jiang, S.J.2    Ye, L.3    Aziz, S.4    Law, P.K.5    Sim, E.K.W.6
  • 64
    • 4344674478 scopus 로고    scopus 로고
    • Angiomyogenesis for cardiac repair using human myoblasts as carriers of human vascular endothelial growth factor
    • DOI 10.1007/s00109-004-0546-z
    • Haider, H.; Ye, L.; Jiang, S.; Ge, R.; Law, P. K.; Chua, T.; Wong, P.; Sim, E. K. Angiomyogenesis for cardiac repair using human myoblasts as carriers of human vascular endothelial growth factor J. Mol. Med. 2004, 82, 539-549 (Pubitemid 39149863)
    • (2004) Journal of Molecular Medicine , vol.82 , Issue.8 , pp. 539-549
    • Haider, H.Kh.1    Ye, L.2    Jiang, S.3    Ge, R.4    Law, P.K.5    Chua, T.6    Wong, P.7    Sim, E.K.W.8
  • 68
    • 78649835433 scopus 로고    scopus 로고
    • Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair
    • Li, T. S.; Cheng, K.; Lee, S. T.; Matsushita, S.; Davis, D.; Malliaras, K.; Zhang, Y.; Matsushita, N.; Smith, R. R.; Marban, E. Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair Stem Cells 2010, 28, 2088-2098
    • (2010) Stem Cells , vol.28 , pp. 2088-2098
    • Li, T.S.1    Cheng, K.2    Lee, S.T.3    Matsushita, S.4    Davis, D.5    Malliaras, K.6    Zhang, Y.7    Matsushita, N.8    Smith, R.R.9    Marban, E.10
  • 76
    • 78650663606 scopus 로고    scopus 로고
    • Stem cells in cardiac repair
    • Henning, R. J. Stem cells in cardiac repair Future Cardiol. 2011, 7, 99-117
    • (2011) Future Cardiol. , vol.7 , pp. 99-117
    • Henning, R.J.1
  • 79
    • 34547857777 scopus 로고    scopus 로고
    • Transplanted embryonic stem cells following mouse myocardial infarction inhibit apoptosis and cardiac remodeling
    • Singla, D. K.; Lyons, G. E.; Kamp, T. J. Transplanted embryonic stem cells following mouse myocardial infarction inhibit apoptosis and cardiac remodeling Am. J. Physiol. 2007, 293, H1308-H1314
    • (2007) Am. J. Physiol. , vol.293
    • Singla, D.K.1    Lyons, G.E.2    Kamp, T.J.3
  • 82
    • 57049181418 scopus 로고    scopus 로고
    • Embryonic stem cells attenuate myocardial dysfunction and inflammation after surgical global ischemia via paracrine actions
    • Crisostomo, P. R.; Abarbanell, A. M.; Wang, M.; Lahm, T.; Wang, Y.; Meldrum, D. R. Embryonic stem cells attenuate myocardial dysfunction and inflammation after surgical global ischemia via paracrine actions Am. J. Physiol. 2008, 295, H1726-H1735
    • (2008) Am. J. Physiol. , vol.295
    • Crisostomo, P.R.1    Abarbanell, A.M.2    Wang, M.3    Lahm, T.4    Wang, Y.5    Meldrum, D.R.6
  • 83
    • 78149334458 scopus 로고    scopus 로고
    • Factors Released from Embryonic Stem Cells Stimulate c-kit-FLK-1(+ve) Progenitor Cells and Enhance Neovascularization
    • Fatma, S.; Selby, D. E.; Singla, R. D.; Singla, D. K. Factors Released from Embryonic Stem Cells Stimulate c-kit-FLK-1(+ve) Progenitor Cells and Enhance Neovascularization Antioxid. Redox Signaling 2010, 13, 1857-1865
    • (2010) Antioxid. Redox Signaling , vol.13 , pp. 1857-1865
    • Fatma, S.1    Selby, D.E.2    Singla, R.D.3    Singla, D.K.4
  • 84
    • 79955060751 scopus 로고    scopus 로고
    • TGF-{beta}2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium
    • Singla, D. K.; Singla, R. D.; Lamm, S.; Glass, C. TGF-{beta}2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium Am. J. Physiol. 2010, 300, H1442-H1450
    • (2010) Am. J. Physiol. , vol.300
    • Singla, D.K.1    Singla, R.D.2    Lamm, S.3    Glass, C.4
  • 85
    • 34247647982 scopus 로고    scopus 로고
    • Transplantation of undifferentiated murine embryonic stem cells in the heart: Teratoma formation and immune response
    • DOI 10.1096/fj.06-6769com
    • Nussbaum, J.; Minami, E.; Laflamme, M. A.; Virag, J. A.; Ware, C. B.; Masino, A.; Muskheli, V.; Pabon, L.; Reinecke, H.; Murry, C. E. Transplantation of undifferentiated murine embryonic stem cells in the heart: teratoma formation and immune response FASEB J. 2007, 21, 1345-1357 (Pubitemid 46684837)
    • (2007) FASEB Journal , vol.21 , Issue.7 , pp. 1345-1357
    • Nussbaum, J.1    Minami, E.2    Laflamme, M.A.3    Virag, J.A.I.4    Ware, C.B.5    Masino, A.6    Muskheli, V.7    Pabon, L.8    Reinecke, H.9    Murry, C.E.10
  • 86
    • 0037238687 scopus 로고    scopus 로고
    • Embryonic stem cells injected into the mouse knee joint form teratomas and subsequently destroy the joint
    • DOI 10.1093/rheumatology/keg024
    • Wakitani, S.; Takaoka, K.; Hattori, T.; Miyazawa, N.; Iwanaga, T.; Takeda, S.; Watanabe, T. K.; Tanigami, A. Embryonic stem cells injected into the mouse knee joint form teratomas and subsequently destroy the joint Rheumatology (Oxford) 2003, 42, 162-165 (Pubitemid 36131582)
    • (2003) Rheumatology , vol.42 , Issue.1 , pp. 162-165
    • Wakitani, S.1    Takaoka, K.2    Hattori, T.3    Miyazawa, N.4    Iwanaga, T.5    Takeda, S.6    Watanabe, T.K.7    Tanigami, A.8
  • 88
    • 79952614332 scopus 로고    scopus 로고
    • Cardiac tumorgenic potential of induced pluripotent stem cells in an immunocompetent host with myocardial infarction
    • Ahmed, R. P.; Ashraf, M.; Buccini, S.; Shujia, J.; Haider, H. Cardiac tumorgenic potential of induced pluripotent stem cells in an immunocompetent host with myocardial infarction Regener. Med. 2011, 6, 171-178
    • (2011) Regener. Med. , vol.6 , pp. 171-178
    • Ahmed, R.P.1    Ashraf, M.2    Buccini, S.3    Shujia, J.4    Haider, H.5
  • 89
    • 70350605496 scopus 로고    scopus 로고
    • Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts
    • Gai, H.; Leung, E. L.; Costantino, P. D.; Aguila, J. R.; Nguyen, D. M.; Fink, L. M.; Ward, D. C.; Ma, Y. Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts Cell Biol. Int. 2009, 33, 1184-1193
    • (2009) Cell Biol. Int. , vol.33 , pp. 1184-1193
    • Gai, H.1    Leung, E.L.2    Costantino, P.D.3    Aguila, J.R.4    Nguyen, D.M.5    Fink, L.M.6    Ward, D.C.7    Ma, Y.8
  • 92
    • 68249094138 scopus 로고    scopus 로고
    • Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells
    • Nelson, T. J.; Martinez-Fernandez, A.; Yamada, S.; Perez-Terzic, C.; Ikeda, Y.; Terzic, A. Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells Circulation 2009, 120, 408-416
    • (2009) Circulation , vol.120 , pp. 408-416
    • Nelson, T.J.1    Martinez-Fernandez, A.2    Yamada, S.3    Perez-Terzic, C.4    Ikeda, Y.5    Terzic, A.6
  • 93
    • 79960011550 scopus 로고    scopus 로고
    • Reprogramming of skeletal myoblasts for induction of pluripotency for tumor free cardiomyogenesis in the infarcted heart
    • Ahmed, R. P.; Ashraf, M.; Buccini, S.; Shujia, J.; Haider, H. Reprogramming of skeletal myoblasts for induction of pluripotency for tumor free cardiomyogenesis in the infarcted heart. Circ. Res. 2011.
    • (2011) Circ. Res.
    • Ahmed, R.P.1    Ashraf, M.2    Buccini, S.3    Shujia, J.4    Haider, H.5
  • 94
    • 33749334628 scopus 로고    scopus 로고
    • Supportive interaction between cell survival signaling and angiocompetent factors enhances donor cell survival and promotes angiomyogenesis for cardiac repair
    • DOI 10.1161/01.RES.0000244687.97719.4f, PII 0000301220060929000015
    • Jiang, S.; Haider, H.; Idris, N. M.; Salim, A.; Ashraf, M. Supportive interaction between cell survival signaling and angiocompetent factors enhances donor cell survival and promotes angiomyogenesis for cardiac repair Circ. Res. 2006, 99, 776-784 (Pubitemid 44498311)
    • (2006) Circulation Research , vol.99 , Issue.7 , pp. 776-784
    • Jiang, S.1    Haider, H.Kh.2    Idris, N.M.3    Salim, A.4    Ashraf, M.5
  • 95
    • 33846353976 scopus 로고    scopus 로고
    • Effects of Cell-Based Angiogenic Gene Therapy at 6 Months: Persistent Angiogenesis and Absence of Oncogenicity
    • DOI 10.1016/j.athoracsur.2006.09.044, PII S0003497506018388
    • Kim, C.; Li, R. K.; Li, G.; Zhang, Y.; Weisel, R. D.; Yau, T. M. Effects of cell-based angiogenic gene therapy at 6 months: persistent angiogenesis and absence of oncogenicity Ann. Thorac. Surg. 2007, 83, 640-646 (Pubitemid 46156925)
    • (2007) Annals of Thoracic Surgery , vol.83 , Issue.2 , pp. 640-646
    • Kim, C.1    Li, R.-K.2    Li, G.3    Zhang, Y.4    Weisel, R.D.5    Yau, T.M.6
  • 96
    • 0035908979 scopus 로고    scopus 로고
    • Cell transplantation for the treatment of acute myocardial infarction using vascular endothelial growth factor-expressing skeletal myoblasts
    • Suzuki, K.; Murtuza, B.; Smolenski, R. T.; Sammut, I. A.; Suzuki, N.; Kaneda, Y.; Yacoub, M. H. Cell transplantation for the treatment of acute myocardial infarction using vascular endothelial growth factor-expressing skeletal myoblasts Circulation 2001, 104, I207-212
    • (2001) Circulation , vol.104 , pp. 207-212
    • Suzuki, K.1    Murtuza, B.2    Smolenski, R.T.3    Sammut, I.A.4    Suzuki, N.5    Kaneda, Y.6    Yacoub, M.H.7
  • 97
    • 0141796313 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
    • DOI 10.1038/nm912
    • Mangi, A. A.; Noiseux, N.; Kong, D.; He, H.; Rezvani, M.; Ingwall, J. S.; Dzau, V. J. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts Nat. Med. 2003, 9, 1195-1201 (Pubitemid 37173705)
    • (2003) Nature Medicine , vol.9 , Issue.9 , pp. 1195-1201
    • Mangi, A.A.1    Noiseux, N.2    Kong, D.3    He, H.4    Rezvani, M.5    Ingwall, J.S.6    Dzau, V.J.7
  • 98
    • 40149090942 scopus 로고    scopus 로고
    • Angiomyogenesis using liposome based vascular endothelial growth factor-165 transfection with skeletal myoblast for cardiac repair
    • Ye, L.; Haider, H.; Tan, R.; Su, L.; Law, P. K.; Zhang, W.; Sim, E. K. Angiomyogenesis using liposome based vascular endothelial growth factor-165 transfection with skeletal myoblast for cardiac repair Biomaterials 2008, 29, 2125-2137
    • (2008) Biomaterials , vol.29 , pp. 2125-2137
    • Ye, L.1    Haider, H.2    Tan, R.3    Su, L.4    Law, P.K.5    Zhang, W.6    Sim, E.K.7
  • 99
    • 34147168698 scopus 로고    scopus 로고
    • Angiopoietin-1 for myocardial angiogenesis: A comparison between delivery strategies
    • DOI 10.1016/j.ejheart.2006.10.022, PII S1388984206003783
    • Ye, L.; Haider, H.; Jiang, S.; Tan, R. S.; Toh, W. C.; Ge, R.; Sim, E. K. Angiopoietin-1 for myocardial angiogenesis: a comparison between delivery strategies Eur. J. Heart Failure 2007, 9, 458-465 (Pubitemid 46562589)
    • (2007) European Journal of Heart Failure , vol.9 , Issue.5 , pp. 458-465
    • Ye, L.1    Haider, H.K.2    Jiang, S.3    Tan, R.S.4    Toh, W.C.5    Ge, R.6    Sim, E.K.W.7
  • 100
    • 77649161196 scopus 로고    scopus 로고
    • Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway
    • Ahmed, R. P.; Haider, K. H.; Shujia, J.; Afzal, M. R.; Ashraf, M. Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway PLoS One 2010, 5, e8576
    • (2010) PLoS One , vol.5 , pp. 8576
    • Ahmed, R.P.1    Haider, K.H.2    Shujia, J.3    Afzal, M.R.4    Ashraf, M.5
  • 103
    • 0037099209 scopus 로고    scopus 로고
    • Retroviral delivery of transforming growth factor-β1 to myeloid dendritic cells: Inhibition of T-cell priming ability and influence on allograft survival
    • Takayama, T.; Kaneko, K.; Morelli, A. E.; Li, W.; Tahara, H.; Thomson, A. W. Retroviral delivery of transforming growth factor-beta1 to myeloid dendritic cells: inhibition of T-cell priming ability and influence on allograft survival Transplantation 2002, 74, 112-119 (Pubitemid 34779220)
    • (2002) Transplantation , vol.74 , Issue.1 , pp. 112-119
    • Takayama, T.1    Kaneko, K.2    Morelli, A.E.3    Li, W.4    Tahara, H.5    Thomson, A.W.6
  • 104
    • 33646887376 scopus 로고    scopus 로고
    • Genotoxicity of Retroviral Integration in Hematopoietic Cells
    • DOI 10.1016/j.ymthe.2006.03.001, PII S1525001606000785
    • Nienhuis, A. W.; Dunbar, C. E.; Sorrentino, B. P. Genotoxicity of retroviral integration in hematopoietic cells Mol. Ther. 2006, 13, 1031-1049 (Pubitemid 43779188)
    • (2006) Molecular Therapy , vol.13 , Issue.6 , pp. 1031-1049
    • Nienhuis, A.W.1    Dunbar, C.E.2    Sorrentino, B.P.3
  • 105
    • 0034986027 scopus 로고    scopus 로고
    • Generation and characterization of E1/E2a/E3/E4-deficient adenoviral vectors encoding human factor VIII
    • DOI 10.1006/mthe.2001.0264
    • Andrews, J. L.; Kadan, M. J.; Gorziglia, M. I.; Kaleko, M.; Connelly, S. Generation and characterization of E1/E2a/E3/E4-deficient adenoviral vectors encoding human factor VIII Mol. Ther. 2001, 3, 329-336 (Pubitemid 32514649)
    • (2001) Molecular Therapy , vol.3 , Issue.3 , pp. 329-336
    • Andrews, J.L.1    Kadan, M.J.2    Gorziglia, M.I.3    Kaleko, M.4    Connelly, S.5
  • 106
    • 4243066440 scopus 로고    scopus 로고
    • Adenovirus-based vascular endothelial growth factor gene delivery to human pancreatic islets
    • DOI 10.1038/sj.gt.3302267
    • Cheng, K.; Fraga, D.; Zhang, C.; Kotb, M.; Gaber, A. O.; Guntaka, R. V.; Mahato, R. I. Adenovirus-based vascular endothelial growth factor gene delivery to human pancreatic islets Gene Ther. 2004, 11, 1105-1116 (Pubitemid 39117306)
    • (2004) Gene Therapy , vol.11 , Issue.14 , pp. 1105-1116
    • Cheng, K.1    Fraga, D.2    Zhang, C.3    Kotb, M.4    Gaber, A.O.5    Guntaka, R.V.6    Mahato, R.I.7
  • 107
    • 27544501923 scopus 로고    scopus 로고
    • Genetic modification of hematopoietic stem cells with nonviral systems: Past progress and future prospects
    • Papapetrou, E. P.; Zoumbos, N. C.; Athanassiadou, A. Genetic modification of hematopoietic stem cells with nonviral systems: past progress and future prospects Gene Ther. 2005, 12 (Suppl. 1) S118-130
    • (2005) Gene Ther. , vol.12 , Issue.SUPPL. 1 , pp. 118-130
    • Papapetrou, E.P.1    Zoumbos, N.C.2    Athanassiadou, A.3
  • 108
    • 33747625392 scopus 로고    scopus 로고
    • Genetic manipulation of human embryonic stem cells by transfection
    • Eiges, R. Genetic manipulation of human embryonic stem cells by transfection Methods Mol. Biol. 2006, 331, 221-239
    • (2006) Methods Mol. Biol. , vol.331 , pp. 221-239
    • Eiges, R.1
  • 109
    • 34250687696 scopus 로고    scopus 로고
    • Efficient transfection of primary cells relevant for cardiovascular research by nucleofection
    • Thiel, C.; Nix, M. Efficient transfection of primary cells relevant for cardiovascular research by nucleofection Methods Mol. Med. 2006, 129, 255-266
    • (2006) Methods Mol. Med. , vol.129 , pp. 255-266
    • Thiel, C.1    Nix, M.2
  • 110
    • 33745035887 scopus 로고    scopus 로고
    • Electroporation of human embryonic stem cells: Small and macromolecule loading and DNA transfection
    • DOI 10.1021/bp0600334
    • Mohr, J. C.; de Pablo, J. J.; Palecek, S. P. Electroporation of human embryonic stem cells: Small and macromolecule loading and DNA transfection Biotechnol. Prog. 2006, 22, 825-834 (Pubitemid 43877451)
    • (2006) Biotechnology Progress , vol.22 , Issue.3 , pp. 825-834
    • Mohr, J.C.1    De Pablo, J.J.2    Palecek, S.P.3
  • 111
    • 59949102798 scopus 로고    scopus 로고
    • Micro-electroporation of mesenchymal stem cells with alternating electrical current pulses
    • Ziv, R.; Steinhardt, Y.; Pelled, G.; Gazit, D.; Rubinsky, B. Micro-electroporation of mesenchymal stem cells with alternating electrical current pulses Biomed. Microdevices 2009, 11, 95-101
    • (2009) Biomed. Microdevices , vol.11 , pp. 95-101
    • Ziv, R.1    Steinhardt, Y.2    Pelled, G.3    Gazit, D.4    Rubinsky, B.5
  • 112
    • 70350324304 scopus 로고    scopus 로고
    • Non-viral gene delivery of DNA polyplexed with nanoparticles transfected into human mesenchymal stem cells
    • Park, J. S.; Na, K.; Woo, D. G.; Yang, H. N.; Kim, J. M.; Kim, J. H.; Chung, H. M.; Park, K. H. Non-viral gene delivery of DNA polyplexed with nanoparticles transfected into human mesenchymal stem cells Biomaterials 2010, 31, 124-132
    • (2010) Biomaterials , vol.31 , pp. 124-132
    • Park, J.S.1    Na, K.2    Woo, D.G.3    Yang, H.N.4    Kim, J.M.5    Kim, J.H.6    Chung, H.M.7    Park, K.H.8
  • 113
    • 34748917848 scopus 로고    scopus 로고
    • Transplantation of nanoparticle transfected skeletal myoblasts overexpressing vascular endothelial growth factor-165 for cardiac repair
    • Ye, L.; Haider, H.; Tan, R.; Toh, W.; Law, P. K.; Tan, W.; Su, L.; Zhang, W.; Ge, R.; Zhang, Y.; Lim, Y.; Sim, E. K. Transplantation of nanoparticle transfected skeletal myoblasts overexpressing vascular endothelial growth factor-165 for cardiac repair Circulation 2007, 116, I113-120
    • (2007) Circulation , vol.116 , pp. 113-120
    • Ye, L.1    Haider, H.2    Tan, R.3    Toh, W.4    Law, P.K.5    Tan, W.6    Su, L.7    Zhang, W.8    Ge, R.9    Zhang, Y.10    Lim, Y.11    Sim, E.K.12
  • 115
    • 73849086119 scopus 로고    scopus 로고
    • PiggyBac transposon-based inducible gene expression in vivo after somatic cell gene transfer
    • Saridey, S. K.; Liu, L.; Doherty, J. E.; Kaja, A.; Galvan, D. L.; Fletcher, B. S.; Wilson, M. H. PiggyBac transposon-based inducible gene expression in vivo after somatic cell gene transfer Mol. Ther. 2009, 17, 2115-2120
    • (2009) Mol. Ther. , vol.17 , pp. 2115-2120
    • Saridey, S.K.1    Liu, L.2    Doherty, J.E.3    Kaja, A.4    Galvan, D.L.5    Fletcher, B.S.6    Wilson, M.H.7
  • 117
    • 66349117300 scopus 로고    scopus 로고
    • Sca-1+ stem cell survival and engraftment in the infarcted heart: Dual role for preconditioning-induced connexin-43
    • Lu, G.; Haider, H. K.; Jiang, S.; Ashraf, M. Sca-1+ stem cell survival and engraftment in the infarcted heart: dual role for preconditioning-induced connexin-43 Circulation 2009, 119, 2587-2596
    • (2009) Circulation , vol.119 , pp. 2587-2596
    • Lu, G.1    Haider, H.K.2    Jiang, S.3    Ashraf, M.4
  • 118
    • 70450240736 scopus 로고    scopus 로고
    • Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2
    • Kim, H. W.; Haider, H. K.; Jiang, S.; Ashraf, M. Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2 J. Biol. Chem. 2009, 284, 33161-33168
    • (2009) J. Biol. Chem. , vol.284 , pp. 33161-33168
    • Kim, H.W.1    Haider, H.K.2    Jiang, S.3    Ashraf, M.4
  • 120
    • 79952068625 scopus 로고    scopus 로고
    • Myocardial Injection with GSK-3{beta}-Overexpressing Bone Marrow-Derived Mesenchymal Stem Cells Attenuates Cardiac Dysfunction after Myocardial Infarction
    • Cho, J.; Zhai, P.; Maejima, Y.; Sadoshima, J. Myocardial Injection With GSK-3{beta}-Overexpressing Bone Marrow-Derived Mesenchymal Stem Cells Attenuates Cardiac Dysfunction After Myocardial Infarction Circ. Res. 2010, 108, 478-489
    • (2010) Circ. Res. , vol.108 , pp. 478-489
    • Cho, J.1    Zhai, P.2    Maejima, Y.3    Sadoshima, J.4
  • 122
    • 38149000936 scopus 로고    scopus 로고
    • Bcl2 enhances induced hematopoietic differentiation of murine embryonic stem cells
    • Wang, Y. Y.; Deng, X.; Xu, L.; Gao, F.; Flagg, T.; May, W. S. Bcl2 enhances induced hematopoietic differentiation of murine embryonic stem cells Exp. Hematol. 2008, 36, 128-139
    • (2008) Exp. Hematol. , vol.36 , pp. 128-139
    • Wang, Y.Y.1    Deng, X.2    Xu, L.3    Gao, F.4    Flagg, T.5    May, W.S.6
  • 123
    • 38849108084 scopus 로고    scopus 로고
    • Stable therapeutic effects of mesenchymal stem cell-based multiple gene delivery for cardiac repair
    • DOI 10.1093/cvr/cvm077
    • Shujia, J.; Haider, H. K.; Idris, N. M.; Lu, G.; Ashraf, M. Stable therapeutic effects of mesenchymal stem cell-based multiple gene delivery for cardiac repair Cardiovasc. Res. 2008, 77, 525-533 (Pubitemid 351197668)
    • (2008) Cardiovascular Research , vol.77 , Issue.3 , pp. 525-533
    • Shujia, J.1    Haider, H.K.2    Idris, N.M.3    Lu, G.4    Ashraf, M.5
  • 124
    • 33745356932 scopus 로고    scopus 로고
    • Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling
    • DOI 10.1161/01.RES.0000225952.61196.39, PII 0000301220060609000012
    • Uemura, R.; Xu, M.; Ahmad, N.; Ashraf, M. Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling Circ. Res. 2006, 98, 1414-1421 (Pubitemid 43948066)
    • (2006) Circulation Research , vol.98 , Issue.11 , pp. 1414-1421
    • Uemura, R.1    Xu, M.2    Ahmad, N.3    Ashraf, M.4
  • 125
    • 33846102433 scopus 로고    scopus 로고
    • 165 and angiopoietin-1
    • DOI 10.1016/j.ejheart.2006.04.008, PII S1388984206001097
    • Ye, L.; Haider, H.; Jiang, S.; Tan, R. S.; Ge, R.; Law, P. K.; Sim, E. K. Improved angiogenic response in pig heart following ischaemic injury using human skeletal myoblast simultaneously expressing VEGF165 and angiopoietin-1 Eur. J. Heart Failure 2007, 9, 15-22 (Pubitemid 46074475)
    • (2007) European Journal of Heart Failure , vol.9 , Issue.1 , pp. 15-22
    • Ye, L.1    Haider, H.Kh.2    Jiang, S.3    Tan, R.S.4    Ge, R.5    Law, P.K.6    Sim, E.K.W.7
  • 126
    • 24644433273 scopus 로고    scopus 로고
    • Maximizing ventricular function with multimodal cell-based gene therapy
    • Yau, T. M.; Kim, C.; Li, G.; Zhang, Y.; Weisel, R. D.; Li, R. K. Maximizing ventricular function with multimodal cell-based gene therapy Circulation 2005, 112, I123-128
    • (2005) Circulation , vol.112 , pp. 123-128
    • Yau, T.M.1    Kim, C.2    Li, G.3    Zhang, Y.4    Weisel, R.D.5    Li, R.K.6
  • 127
    • 33847258744 scopus 로고    scopus 로고
    • Cell-Based VEGF Delivery Prevents Donor Cell Apoptosis after Transplantation
    • DOI 10.1016/j.athoracsur.2006.04.008, PII S0003497506006989
    • Ye, L.; Haider, H.; Guo, C.; Sim, E. K. Cell-based VEGF delivery prevents donor cell apoptosis after transplantation Ann. Thorac. Surg. 2007, 83, 1233-1234 (Pubitemid 46328773)
    • (2007) Annals of Thoracic Surgery , vol.83 , Issue.3 , pp. 1233-1234
    • Ye, L.1    Haider, H.Kh.2    Guo, C.3    Sim, E.K.W.4
  • 128
    • 58149345104 scopus 로고    scopus 로고
    • IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem
    • Haider, H.; Jiang, S.; Idris, N. M.; Ashraf, M. IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair Circ. Res. 2008, 103, 1300-1308
    • (2008) Circ. Res. , vol.103 , pp. 1300-1308
    • Haider, H.1    Jiang, S.2    Idris, N.M.3    Ashraf, M.4
  • 129
    • 34047130642 scopus 로고    scopus 로고
    • Ex vivo delivered stromal cell-derived factor-1α promotes stem cell homing and induces angiomyogenesis in the infarcted myocardium
    • DOI 10.1016/j.yjmcc.2007.02.001, PII S002228280700017X
    • Elmadbouh, I.; Haider, H.; Jiang, S.; Idris, N. M.; Lu, G.; Ashraf, M. Ex vivo delivered stromal cell-derived factor-1alpha promotes stem cell homing and induces angiomyogenesis in the infarcted myocardium J. Mol. Cell. Cardiol. 2007, 42, 792-803 (Pubitemid 46527603)
    • (2007) Journal of Molecular and Cellular Cardiology , vol.42 , Issue.4 , pp. 792-803
    • Elmadbouh, I.1    Haider, H.K.2    Jiang, S.3    Idris, N.M.4    Lu, G.5    Ashraf, M.6
  • 130
    • 80053495545 scopus 로고    scopus 로고
    • Activation of diverse signaling pathways by ex-vivo delivery of multiple cytokines to mobilize progenitor cells for cardiac repair
    • in press
    • Konoplyannikov, M.; Haider, H. Kh.; Lai, V. K.; Ahmed, P. H.; Jiang, S.; Ashraf, M. Activation of diverse signaling pathways by ex-vivo delivery of multiple cytokines to mobilize progenitor cells for cardiac repair. Cardiovasc. Res. 2011, in press.
    • (2011) Cardiovasc. Res.
    • Konoplyannikov, M.1    Haider, H.Kh.2    Lai, V.K.3    Ahmed, P.H.4    Jiang, S.5    Ashraf, M.6
  • 131
    • 79952114597 scopus 로고    scopus 로고
    • Small molecules in cellular reprogramming and differentiation
    • Yuan, X.; Li, W.; Ding, S. Small molecules in cellular reprogramming and differentiation Prog. Drug Res. 2010, 67, 253-266
    • (2010) Prog. Drug Res. , vol.67 , pp. 253-266
    • Yuan, X.1    Li, W.2    Ding, S.3
  • 134
    • 80053531606 scopus 로고    scopus 로고
    • Cardiac tumorgenic potential of induced pluripotent stem cells in immunocompetent host: A note of caution
    • Ahmed, R. P. H., A., M., Buccini, S., Jiang Shujia, J., Haider, H.Kh. Cardiac tumorgenic potential of induced pluripotent stem cells in immunocompetent host: a note of caution. Regener. Med. 2011.
    • (2011) Regener. Med.
    • Ahmed, R.P.H.1    Buccini, A.M.2    Jiang Shujia, S.3    Haider, J.4    Kh, H.5
  • 136
    • 66649127942 scopus 로고    scopus 로고
    • Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors
    • Takeuchi, J. K.; Bruneau, B. G. Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors Nature 2009, 459, 708-711
    • (2009) Nature , vol.459 , pp. 708-711
    • Takeuchi, J.K.1    Bruneau, B.G.2
  • 137
    • 79952273710 scopus 로고    scopus 로고
    • Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
    • Efe, J. A.; Hilcove, S.; Kim, J.; Zhou, H.; Ouyang, K.; Wang, G.; Chen, J.; Ding, S. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy Nat. Cell Biol. 2010, 13, 215-222
    • (2010) Nat. Cell Biol. , vol.13 , pp. 215-222
    • Efe, J.A.1    Hilcove, S.2    Kim, J.3    Zhou, H.4    Ouyang, K.5    Wang, G.6    Chen, J.7    Ding, S.8
  • 138
    • 78149403591 scopus 로고    scopus 로고
    • MacroRNA underdogs in a microRNA world: Evolutionary, regulatory, and biomedical significance of mammalian long non-protein-coding RNA
    • Lipovich, L.; Johnson, R.; Lin, C. Y. MacroRNA underdogs in a microRNA world: evolutionary, regulatory, and biomedical significance of mammalian long non-protein-coding RNA Biochim. Biophys. Acta 2010, 1799, 597-615
    • (2010) Biochim. Biophys. Acta , vol.1799 , pp. 597-615
    • Lipovich, L.1    Johnson, R.2    Lin, C.Y.3
  • 141
    • 77954697250 scopus 로고    scopus 로고
    • Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells
    • Doebele, C.; Bonauer, A.; Fischer, A.; Scholz, A.; Reiss, Y.; Urbich, C.; Hofmann, W. K.; Zeiher, A. M.; Dimmeler, S. Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells Blood 2010, 115, 4944-4950
    • (2010) Blood , vol.115 , pp. 4944-4950
    • Doebele, C.1    Bonauer, A.2    Fischer, A.3    Scholz, A.4    Reiss, Y.5    Urbich, C.6    Hofmann, W.K.7    Zeiher, A.M.8    Dimmeler, S.9
  • 142
    • 77958097322 scopus 로고    scopus 로고
    • Mitochondria-specific transgenic overexpression of connexin-43 simulates preconditioning-induced cytoprotection of stem cells
    • Lu, G.; Haider, H.; Porollo, A.; Ashraf, M. Mitochondria-specific transgenic overexpression of connexin-43 simulates preconditioning-induced cytoprotection of stem cells Cardiovasc. Res. 2011, 88, 277-286
    • (2011) Cardiovasc. Res. , vol.88 , pp. 277-286
    • Lu, G.1    Haider, H.2    Porollo, A.3    Ashraf, M.4


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