Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI)

Circulation

Volumn 106, Issue 24, 2002, Pages 3009-3017

  Assmus, Birgit ^a   Schächinger, Volker ^a   Teupe, Claudius ^a   Britten, Martina ^a   Lehmann, Ralf ^a   Döbert, Natascha ^a   Grünwald, Frank ^a   Aicher, Alexandra ^a   Urbich, Carmen ^a   Martin, Hans ^a   Hoelzer, Dieter ^a   Dimmeler, Stefanie ^a   Zeiher, Andreas M ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Cells; Myocardial infarction; Remodeling; Transplantation

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; BLOOD CELL; BONE MARROW CELL; CELL REGENERATION; CELL TRANSPLANTATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRESSLER SYNDROME; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART VENTRICLE WALL MOTION; HUMAN; INFLAMMATION; INTRACORONARY INFUSION; ISCHEMIC HEART DISEASE; MALE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SAFETY; SCORING SYSTEM; STEM CELL; SYSTOLIC BLOOD PRESSURE;

CELLS, CULTURED; CORONARY ANGIOGRAPHY; CORONARY CIRCULATION; ECHOCARDIOGRAPHY; FEMALE; FLUORODEOXYGLUCOSE F18; FOLLOW-UP STUDIES; HEART; HUMANS; INFUSIONS, INTRA-ARTERIAL; MALE; MIDDLE AGED; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION; REGENERATION; STEM CELL TRANSPLANTATION; STEM CELLS; STROKE VOLUME; THERAPIES, INVESTIGATIONAL; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; VENTRICULAR REMODELING;

EID: 0037058848     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000043246.74879.CD     Document Type: Article

References (32)

1. Lange RA, Hillis LD. Reperfusion therapy in acute myocardial infarction. N Engl J Med. 2002;346:954-955.
2. Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction: Experimental observations and clinical implications. Circulation. 1990;81:1161-1172.
3. Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature. 2001;410:701-705.
4. Kocher AA, Schuster MD, Szabolcs MJ, et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med. 2001;7:430-436.
5. Kawamoto A, Gwon HC, Iwaguro H, et al. Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation. 2001;103:634-637.
6. Fuchs S, Baffour R, Zhou YF, et al. Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia. J Am Coll Cardiol. 2001;37:1726-1732.
7. Orlic D, Kajstura J, Chimenti S, et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci U S A. 2001;98:10344-10349.
8. Kalka C, Masuda H, Takahashi T, et al. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci U S A. 2000;97:3422-3427.
9. Dimmeler S, Aicher A, Vasa M, et al. HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J Clin Invest. 2001;108:391-397.
10. Vasa M, Fichtlscherer S, Adler K, et al. Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease. Circulation. 2001;103:2885-2890.
11. Vasa M, Fichtlscherer S, Aicher A, et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res. 2001;89:E1-E7.
12. Dodge HT, Sandler H, Ballew DW, et al. The use of biplane angiography for the measurement of left ventricular volume in man. Eur Heart J. 1960;60:762-776.
13. Sheehan FH, Bolson EL, Dodge HT, et al. Advantages and applications of the centerline method for characterizing regional ventricular function. Circulation. 1986;74:293-305.
14. Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation. 2000;101:1899-1906.
15. Pierard LA, De Landsheere CM, Berthe C, et al. Identification of viable myocardium by echocardiography during dobutamine infusion in patients with myocardial infarction after thrombolytic therapy: Comparison with positron emission tomography. J Am Coll Cardiol. 1990;15:1021-1031.
16. Schiller NB, Shah PM, Crawford M, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography: American Society of Echocardiography Committee on Standards, Subcommittee on Quantiration of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr. 1989; 2:358-367.
17. Melin JA, Becker LC. Quantitative relationship between global left ventricular thallium uptake and blood flow: Effects of propranolol, ouabain, dipyridamole, and coronary artery occlusion. J Nucl Med. 1986;27:641-652.
18. Bax JJ, Veening MA, Visser FC, et al. Optimal metabolic conditions during fluorine-18 fluorodeoxyglucose imaging; a comparative study using different protocols. Eur J Nucl Med. 1997;24:35-41.
19. Lewis P, Nunan T, Dynes A, et al. The use of low-dose intravenous insulin in clinical myocardial F-18 FDG PET scanning. Clin Nucl Med. 1996;21:15-18.
20. Rentrop KP, Cohen M, Blanke H, et al. Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. J Am Coll Cardiol. 1985;5:587-592.
21. Jackson KA, Majka SM, Wang H, et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest. 2001; 107:1395-1402.
22. Hirschi KK, Goodell MA. Hematopoietic, vascular and cardiac fates of bone marrow-derived stem cells. Gene Ther. 2002;9:648-652.
23. Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature. 2002;418:41-49.
24. Takahashi T, Kalka C, Masuda H, et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med. 1999;5:434-438.
25. Murohara T, Ikeda H, Duan J, et al. Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J Clin Invest. 2000;105:1527-1536.
26. Tateishi-Yuyama E, Matsubara H, Murohara T, et al. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone marrow cells: A pilot study and a randomized controlled trial. Lancet. 2002;360:427-435.
27. Strauer BE, Brehm M, Zeus T, et al. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation. 2002;106:online.
28. Kern MJ. Coronary physiology revisited: Practical insights from the cardiac catheterization laboratory. Circulation. 2000;101:1344-1351.
29. Menasche P, Hagege AA, Scorsin M, et al. Myoblast transplantation for heart failure. Lancet. 2001;357:279-280.
30. Pfeffer MA, Braunwald E, Moye LA, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: Results of the survival and ventricular enlargement trial: The SAVE Investigators. N Engl J Med. 1992;327:669-677.
31. Stone GW, Grines CL, Cox DA, et al. Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction. N Engl J Med. 2002;346:957-966.
32. Montalescot G, Barragan P, Wittenberg O, et al. Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction. N Engl J Med. 2001;344:1895-1903.